proline and Benign Neoplasms

proline has been researched along with Benign Neoplasms in 85 studies

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199014 (16.47)18.7374
1990's4 (4.71)18.2507
2000's23 (27.06)29.6817
2010's20 (23.53)24.3611
2020's24 (28.24)2.80

Authors

AuthorsStudies
AlKhazindar, M; Bojarska, J; El-Mowafi, SA; Elnagdy, S; Mieczkowski, A; Mohammed, EHM; Parang, K; Shalash, AO; Skwarczynski, M; Toth, I; Wolf, WM; Ziora, ZM1
Phang, JM4
Bridges, E; Cuozzo, F; Eales, KL; Escribano-Gonzalez, C; Eskla, KL; Harris, AL; Hodson, DJ; Lavery, GG; Luuk, H; Nixon, C; Rana, H; Roberts, J; Shaaban, A; Tennant, DA; Vellama, H; Vera-Siguenza, E; Vettore, LA; Walker, PD; Westbrook, RL1
Bersenev, A; Cao, H; Chen, S; Chow, RD; Clark, P; Dai, X; Dong, MB; Du, Y; Errami, Y; Guo, J; Kim, HR; Lam, SZ; Montgomery, RR; Park, JJ; Peng, L; Tang, E; Wang, G; Yang, Q; Ye, L; Zhang, Y1
Greenbaum, B; Hoyos, D; Levine, AJ1
Madrigal Perez, LA; Nava, GM1
Gao, Y; Li, L; Li, Y; Xiu, M1
Enyedy, ÉA; Kovács, H; May, NV; Nezafat Yazdi, Z; Özvegy-Laczka, C; Pivarcsik, T; Pósa, SP; Pósa, V; Spengler, G; Szakács, G; Szatmári, I; Tóth, S; Ugrai, I1
Blagih, J; Fendt, SM; Hennequart, M; Labuschagne, CF; Legrave, NM; Pilley, SE; Vandekeere, A; Vousden, KH1
Bodor, A; Ecsédi, P; Nyitray, L; Sebák, F1
Kay, EJ; Rufini, A; Zanivan, S1
Barber, LJ; Bassani-Sternberg, M; Choudhary, JS; Gerlinger, M; Newey, A; Yu, L1
Baszanowska, W; Huynh, TYL; Lewoniewska, S; Palka, J; Zareba, I1
Bai, C; Chen, C; Chu, Q; Cui, Y; Li, B; Liu, M; Ruan, Y; Wang, Y; Yang, C; Ying, G1
Gao, J; Mao, J; Tang, J; Wang, X; Zhang, H; Zhang, J1
Béhé, M; Berger, P; De Foresta, M; Deupi, X; Dobitz, S; Ritler, A; Romantini, N; Schibli, R; Walther, C; Wennemers, H; Wilhelm, P1
Armando, R; Cabrera, M; Chinestrad, P; Gomez, DE; Gómez, DLM; Maggio, J; Menna, PL; Pifano, M1
Chang, JF; Gan, ZX; Liu, KN; Liu, YZ; Sun, F; Sun, J; Yang, XM; Zhang, L; Zhang, W1
Bogner, AN; Stiers, KM; Tanner, JJ1
Borgatti, M; Forlani, G; Petrollino, D; Ragno, D; Sabbioni, G1
Bie, J; Li, Y; Liu, M; Luo, J; Song, C1
Liu, S; Liu, Y; Mao, C; Shi, Y; Tao, Y; Xiao, D1
Tennant, DA; Vettore, LA; Westbrook, RL1
Geng, P; Qin, W; Xu, G1
Burke, TR; Dyba, M; Hamazaki, J; Hymel, D; Liu, F; Lu, X; Murata, S; Nowicka, U; Randles, L; Sridharan, V; Tarasov, SG; Tarasova, NI; Walters, KJ; Zhao, XZ1
Chng, WJ; Chu-Farseeva, YY; Dymock, BW; Mustafa, N; Poulsen, A; Tan, EC; Yen, JJY1
Chen, S; Liu, B; Liu, L; Liu, M; Luo, J; Qi, H; Ren, M; Vucenik, I; Wang, Z; Yang, X; Yu, M; Zhu, WG; Zou, J1
Dahabreh, IJ; Lau, J; Murray, S; Schmid, CH; Trikalinos, TA; Varvarigou, V1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Gatter, KC; Harris, AL; Li, D; Masiero, M; McIntyre, A; Pezzella, F; Schofield, CJ; Snell, CE; Turley, H1
Amidon, GL; Dahan, A; Landowski, CP; Mittal, S; Wolk, O; Wu, Z; Yang, P1
Fischer, JW; Hancock, CN; Liu, W; Phang, JM1
Brimble, MA; Harris, PW1
Czyzewska, U; Kononczuk, J; Miltyk, W; Moczydlowska, J; Palka, J; Surażyński, A1
Abboud, MI; Cantrelle, FX; Chowdhury, R; Claridge, TD; Domene, C; Ge, W; Hardy, AP; Landrieu, I; Leung, IK; Pugh, CW; Ratcliffe, PJ; Schofield, CJ; Tian, YM1
Asara, JM; Chakraborty, AA; Cheng, JQ; Gan, W; Guo, J; Inuzuka, H; Kaelin, WG; Liu, P; Novak, J; Signoretti, S; Toker, A; Wang, B; Wei, W; Yuan, M; Zhang, J; Zhang, L; Zhang, Q; Zheng, X1
Chen, Y; Erber, L; Gao, Y; Liu, B; Ruan, HB; Zhou, T1
Allen, DW; Carolan, VA; Claude, E; Clench, MR; Djidja, MC; Scriven, P1
Liu, Y; Pandhare, J; Phang, JM1
Coenen, HH; Haas, R; Hamacher, K; Kobbe, G; Langen, KJ; Pauleit, D; Salber, D; Stoffels, G1
Jodoin, J; Laroche-Pierre, S; LeBlanc, AC1
Bastús, NG; Giralt, E; Kogan, MJ; López-Iglesias, C; Pereiro, E; Pujals, S; Puntes, VF1
Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y1
Abu-Zahra, H; Banerjee, S; Bergwitz, C; Jüppner, H; Kaji, H; Miyauchi, A; Sugimoto, T1
Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW1
Kaelin, WG1
Clark, BR; Fox, D; Leroy, J; Murphy, CD; O'Connor, S1
Liu, W; Phang, JM1
Bonner, JD; Boyd, J; Chong, G; De La Chapelle, A; Ellis, NA; Farber, D; Figer, A; Foulkes, WD; Friedman, E; Gaff, CL; Gebert, J; Gordon, PH; Greenwood, CM; Gregersen, PK; Gruber, SB; Hamel, N; Hampel, H; Horwitz, M; King, MC; Lee, C; MacNamara, E; Macrae, FA; Marcus, V; Markowitz, A; Nafa, K; Offit, K; Paillerets, BB; Rennert, G; Shia, J; Thiffault, I; Tomsho, L; Walsh, T; Weitzel, JN1
Della Pietra, AC; Dumont, P; George, DL; Leu, JI; Murphy, M1
Albright, CF; Arnone, M; Grafstrom, RH; Kendall, M; Pan, W; Seitz, SP; Wasserman, ZR1
Bojesen, SE; Nordestgaard, BG; Tybjaerg-Hansen, A1
HERMAN, C; HIWETT, J; VAN ROBERTSON, WB1
ERB, W; HEMPEL, K1
BAUER, JM; WU, C1
LORINCZ, AB; RYAN, WL1
Akaike, T; Fang, J; Greish, K; Maeda, H; Sawa, T1
Lu, KP1
Braunstein, I; Brosh, R; Erez, N; Ginsberg, D; Kogan, I; Milyavsky, M; Rotter, V; Shats, I; Stambolsky, P; Tang, X; Tzukerman, M1
Kentsis, A; Miller, F; Osman, R; Pan, ZQ1
Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C1
Krummel, KA; Lee, CJ; Liu, CW; Rodewald, LW; Tang, M; Toledo, F; Wahl, GM1
Fojo, T1
Krummel, KA; Lee, CJ; Liu, CW; Rodewald, LW; Toledo, F; Wahl, GM1
Baiula, M; Cardillo, G; Gentilucci, L; Spampinato, S; Sparta, A; Squassabia, F; Tolomelli, A1
Ishida, T; Kashima, T; Makino, K; Soemantri, A1
Ishibashi, M; Ohtsuki, T1
Donald, SP; Liu, Y; Pandhare, J; Phang, JM1
Hamacher, K; Herz, M; Schwaiger, M; Senekowitsch-Schmidtke, R; Stöcklin, G; Wester, HJ1
Jennes, L; Kakar, SS1
Bartholomew, B; Collard, MW; Huggenvik, JI; Michelson, RJ; Persinger, J; Ziemba, AJ1
Keshava, C; McCanlies, EC; Sharp, DS; Sun, Y; Weston, A1
Liou, YC; Lu, KP; Zhou, XZ1
Pees, HW1
Forman, D1
Jacob, J1
Keiser, HR; Sjoerdsma, A; Stein, HD1
Freytag, G; Grasedyck, K; Lindner, J1
Kimmig, J; Kreysel, HW1
Flowers, ES1
Stiller, KJ1
Hahn, K; Jesdinsky, HJ; Ladner, HA1

Reviews

23 review(s) available for proline and Benign Neoplasms

ArticleYear
Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.
    Biomolecules, 2021, 10-14, Volume: 11, Issue:10

    Topics: Diketopiperazines; Dipeptides; Drug Discovery; Humans; Neoplasms; Peptides, Cyclic; Proline

2021
The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein.
    Cell death and differentiation, 2022, Volume: 29, Issue:5

    Topics: Genotype; Humans; Mutation, Missense; Neoplasms; Phenotype; Proline; Tumor Suppressor Protein p53

2022
Metabolic profile of the Warburg effect as a tool for molecular prognosis and diagnosis of cancer.
    Expert review of molecular diagnostics, 2022, Volume: 22, Issue:4

    Topics: Amino Acids, Branched-Chain; Glucose; Glutamine; Humans; Metabolome; Neoplasms; Proline

2022
An update regarding the role of WNK kinases in cancer.
    Cell death & disease, 2022, 09-19, Volume: 13, Issue:9

    Topics: Alanine; Animals; Bicarbonates; Mammals; Neoplasms; Neovascularization, Pathologic; Proline; Serine; Sodium Chloride Symporters; Threonine

2022
Proline metabolism shapes the tumor microenvironment: from collagen deposition to immune evasion.
    Current opinion in biotechnology, 2023, Volume: 84

    Topics: Collagen; Extracellular Matrix; Humans; Immune Evasion; Neoplasms; Proline; Tumor Microenvironment

2023
Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy.
    Molecular and cellular biochemistry, 2020, Volume: 466, Issue:1-2

    Topics: Apoptosis; Autophagy; Humans; Neoplasm Proteins; Neoplasms; Proline; Proline Oxidase; Signal Transduction

2020
Structure, biochemistry, and gene expression patterns of the proline biosynthetic enzyme pyrroline-5-carboxylate reductase (PYCR), an emerging cancer therapy target.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Animals; Gene Expression; Humans; Neoplasms; Proline; Pyrroline Carboxylate Reductases; Up-Regulation

2021
PYCR, a key enzyme in proline metabolism, functions in tumorigenesis.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Animals; Carcinogenesis; Cell Cycle; Humans; Neoplasms; Oxidation-Reduction; Proline; Pyrroline Carboxylate Reductases

2021
Proline dehydrogenase in cancer: apoptosis, autophagy, nutrient dependency and cancer therapy.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Animals; Apoptosis; Autophagy; Cellular Senescence; Humans; Neoplasms; Proline; Proline Oxidase; Signal Transduction

2021
Proline metabolism and redox; maintaining a balance in health and disease.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Animals; Homeostasis; Humans; Neoplasms; Oxidation-Reduction; Proline; Protein Biosynthesis; Reactive Oxygen Species

2021
Proline metabolism in cancer.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Animals; Apoptosis; Cell Proliferation; Humans; Neoplasm Metastasis; Neoplasms; Proline

2021
Proline Metabolism in Cell Regulation and Cancer Biology: Recent Advances and Hypotheses.
    Antioxidants & redox signaling, 2019, 02-01, Volume: 30, Issue:4

    Topics: Humans; Neoplasms; Oxidation-Reduction; Proline; Proline Oxidase; Tumor Suppressor Protein p53

2019
Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer.
    American journal of epidemiology, 2013, Jun-15, Volume: 177, Issue:12

    Topics: Alleles; Bayes Theorem; Breast Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Female; Genes, p53; Genotyping Techniques; Humans; Loss of Heterozygosity; Lung Neoplasms; Neoplasms; Ovarian Neoplasms; Polymorphism, Genetic; Proline

2013
Proline metabolism and cancer: emerging links to glutamine and collagen.
    Current opinion in clinical nutrition and metabolic care, 2015, Volume: 18, Issue:1

    Topics: Animals; Collagen; Glutamine; Humans; Neoplasms; Proline; Proto-Oncogene Mas

2015
Proline Oxidase (POX) as A Target for Cancer Therapy.
    Current drug targets, 2015, Volume: 16, Issue:13

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Humans; Molecular Targeted Therapy; Neoplasms; Oxidative Stress; Proline; Proline Oxidase; Reactive Oxygen Species; Signal Transduction

2015
Proline metabolism and cancer.
    Frontiers in bioscience (Landmark edition), 2012, 01-01, Volume: 17, Issue:5

    Topics: Animals; Down-Regulation; Genes, Tumor Suppressor; Humans; Neoplasms; Proline; Proline Oxidase; Xenograft Model Antitumor Assays

2012
Pinning down cell signaling, cancer and Alzheimer's disease.
    Trends in biochemical sciences, 2004, Volume: 29, Issue:4

    Topics: Alzheimer Disease; CDC2-CDC28 Kinases; Cell Cycle; Cyclin-Dependent Kinase 2; Humans; Models, Biological; Models, Molecular; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Phosphoserine; Phosphothreonine; Proline; Proline-Directed Protein Kinases; Protein Structure, Tertiary; Signal Transduction

2004
Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis.
    Medicinal research reviews, 2008, Volume: 28, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benz(a)Anthracenes; Caspases; Drug Screening Assays, Antitumor; Humans; Isoflavones; Neoplasms; Proline; Protein Kinases; Receptors, Death Domain; Sesquiterpenes; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand

2008
The metabolism of proline, a stress substrate, modulates carcinogenic pathways.
    Amino acids, 2008, Volume: 35, Issue:4

    Topics: Adenosine Triphosphate; Apoptosis; Autophagy; Catalysis; Gene Expression Regulation, Enzymologic; Ligands; Models, Biological; Neoplasms; PPAR delta; Proline; Proline Oxidase; Protein Kinases; Thiazolidinediones; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53

2008
Pinning down proline-directed phosphorylation signaling.
    Trends in cell biology, 2002, Volume: 12, Issue:4

    Topics: Alzheimer Disease; Amino Acid Motifs; Animals; Humans; Models, Molecular; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Proline; Protein Conformation; Proteins; Signal Transduction

2002
The regulatory functions of proline and pyrroline-5-carboxylic acid.
    Current topics in cellular regulation, 1985, Volume: 25

    Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship

1985
Dietary exposure to N-nitroso compounds and the risk of human cancer.
    Cancer surveys, 1987, Volume: 6, Issue:4

    Topics: Diet; Environmental Exposure; Humans; Neoplasms; Nitrates; Nitrites; Nitrosamines; Nitroso Compounds; Proline

1987
The practice and application of electron microscope autoradiography.
    International review of cytology, 1971, Volume: 30

    Topics: Animals; Autoradiography; Bacillus subtilis; Carbohydrates; Carbon Isotopes; DNA; Emulsions; Escherichia coli; Guinea Pigs; Histocytochemistry; Histological Techniques; L Cells; Leucine; Lipids; Mathematics; Mice; Microscopy, Electron; Microtomy; Neoplasms; Pancreas; Paramecium; Photomicrography; Plants; Proline; Proteins; Radiation Effects; Radioisotopes; Rats; RNA; Staining and Labeling; Sulfur Isotopes; Thymidine; Thyroid Gland; Time Factors; Tritium; Triturus; Viruses; Xenopus

1971

Other Studies

62 other study(ies) available for proline and Benign Neoplasms

ArticleYear
Perspectives, past, present and future: the proline cycle/proline-collagen regulatory axis.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Collagen; Extracellular Matrix; Humans; Hydroxyproline; Neoplasms; Proline; Small Molecule Libraries

2021
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
    Cell reports, 2022, 02-01, Volume: 38, Issue:5

    Topics: Cell Proliferation; Citric Acid Cycle; delta-1-Pyrroline-5-Carboxylate Reductase; Humans; Mitochondria; Neoplasms; Oxygen; Proline; Pyrroline Carboxylate Reductases; Tumor Microenvironment

2022
A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy.
    Cell metabolism, 2022, 04-05, Volume: 34, Issue:4

    Topics: CD8-Positive T-Lymphocytes; Clustered Regularly Interspaced Short Palindromic Repeats; Gain of Function Mutation; Humans; Neoplasms; Proline; Receptors, Chimeric Antigen

2022
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
    International journal of molecular sciences, 2022, Dec-29, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Coordination Complexes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Ferric Compounds; Ferrous Compounds; Humans; Ions; Ligands; Neoplasms; Organometallic Compounds; Proline; Ruthenium; Solubility; Water

2022
Loss of attachment promotes proline accumulation and excretion in cancer cells.
    Science advances, 2023, 09-08, Volume: 9, Issue:36

    Topics: Amino Acids; Biological Transport; Extracellular Matrix; Macrophages; Neoplasms; Proline

2023
Assignment of the disordered, proline-rich N-terminal domain of the tumour suppressor p53 protein using
    Biomolecular NMR assignments, 2023, Volume: 17, Issue:2

    Topics: Humans; Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Proline; Protons; Tumor Suppressor Protein p53

2023
Multifactorial Remodeling of the Cancer Immunopeptidome by IFNγ.
    Cancer research communications, 2023, Nov-17, Volume: 3, Issue:11

    Topics: Antigens; Humans; Interferon-gamma; Neoplasms; Peptides; Proline; Proteomics

2023
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
    The Journal of experimental medicine, 2020, 03-02, Volume: 217, Issue:3

    Topics: A549 Cells; Animals; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Female; Glutamine; HeLa Cells; Hep G2 Cells; Humans; Lipogenesis; MCF-7 Cells; Metabolic Networks and Pathways; Mice; Mice, Nude; Neoplasms; Proline

2020
Design, synthesis, and biological evaluation of 4-phenoxybenzenesulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors.
    Bioscience trends, 2020, Jul-17, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Caffeic Acids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Enzyme Assays; Humans; Hydroxamic Acids; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Molecular Docking Simulation; Neoplasms; Proline; Rats; Recombinant Proteins; Sulfones

2020
Distance-Dependent Cellular Uptake of Oligoproline-Based Homobivalent Ligands Targeting GPCRs-An Experimental and Computational Analysis.
    Bioconjugate chemistry, 2020, 10-21, Volume: 31, Issue:10

    Topics: Animals; Cell Line, Tumor; Female; HEK293 Cells; Humans; Ligands; Mice, SCID; Molecular Dynamics Simulation; Neoplasms; Oligopeptides; Proline; Receptors, Bombesin; Receptors, Somatostatin

2020
Rational design of PIN1 inhibitors for cancer treatment based on conformational diversity analysis and docking based virtual screening.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:13

    Topics: Antineoplastic Agents; Early Detection of Cancer; Enzyme Inhibitors; Humans; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Phosphorylation; Proline

2022
Nucleotide variation in histone H2BL drives crossalk of histone modification and promotes tumour cell proliferation by upregulating c-Myc.
    Life sciences, 2021, Apr-15, Volume: 271

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Genetic Variation; HEK293 Cells; Histones; Humans; Lentivirus; Leucine; Mice; Mice, Nude; Mutation; Neoplasms; Nucleotides; Proline; Proto-Oncogene Proteins c-myc; Up-Regulation; Xenograft Model Antitumor Assays

2021
Phenyl-substituted aminomethylene-bisphosphonates inhibit human P5C reductase and show antiproliferative activity against proline-hyperproducing tumour cells.
    Journal of enzyme inhibition and medicinal chemistry, 2021, Volume: 36, Issue:1

    Topics: Cell Proliferation; delta-1-Pyrroline-5-Carboxylate Reductase; Diphosphonates; Humans; Neoplasms; Proline; Pyrroline Carboxylate Reductases

2021
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.
    Nature communications, 2017, 06-09, Volume: 8

    Topics: Antineoplastic Agents; Benzylidene Compounds; Biophysics; Drug Screening Assays, Antitumor; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; Hexosyltransferases; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Neoplasms; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Domains; Ubiquitin Thiolesterase

2017
Design and synthesis of potent dual inhibitors of JAK2 and HDAC based on fusing the pharmacophores of XL019 and vorinostat.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Antineoplastic Agents; Apoptosis; Drug Design; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Janus Kinase 2; Molecular Docking Simulation; Neoplasms; Proline; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship; Vorinostat

2018
SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism.
    Neoplasia (New York, N.Y.), 2019, Volume: 21, Issue:7

    Topics: Acetylation; Cell Proliferation; delta-1-Pyrroline-5-Carboxylate Reductase; Humans; MCF-7 Cells; Mitochondria; Neoplasms; Peptide Fragments; Proline; Pyrroline Carboxylate Reductases; Sialoglycoproteins; Sirtuin 3

2019
Effect of a nutrient mixture on matrix metalloproteinase-9 dimers in various human cancer cell lines.
    International journal of oncology, 2014, Volume: 44, Issue:3

    Topics: Antioxidants; Ascorbic Acid; Dimerization; Gelatinases; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Lysine; Matrix Metalloproteinase 9; Neoplasms; Proline; Urokinase-Type Plasminogen Activator

2014
Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Kaplan-Meier Estimate; MCF-7 Cells; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Procollagen-Proline Dioxygenase; Prognosis; Proline; Up-Regulation

2014
Dipeptidyl peptidase IV as a potential target for selective prodrug activation and chemotherapeutic action in cancers.
    Molecular pharmaceutics, 2014, Dec-01, Volume: 11, Issue:12

    Topics: Animals; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dipeptides; Dipeptidyl Peptidase 4; Humans; Melphalan; Neoplasms; Oligopeptides; Prodrugs; Proline; Swine

2014
Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.
    Biopolymers, 2015, Volume: 104, Issue:2

    Topics: Antigens, Neoplasm; Membrane Proteins; Neoplasms; Peptides; Proline; Thiazoles

2015
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
    Nature communications, 2016, 08-26, Volume: 7

    Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Fibroblasts; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoenzymes; Mice; Molecular Dynamics Simulation; Neoplasms; Oxygen; Polycythemia; Proline; Protein Binding; Protein Domains; Recombinant Proteins; Structure-Activity Relationship

2016
pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner.
    Science (New York, N.Y.), 2016, 08-26, Volume: 353, Issue:6302

    Topics: Cell Line, Tumor; Enzyme Activation; Humans; Hydroxylation; Hypoxia-Inducible Factor-Proline Dioxygenases; Mutation; Neoplasms; Phosphorylation; Proline; Proto-Oncogene Proteins c-akt; Tumor Hypoxia; Tumor Microenvironment; Von Hippel-Lindau Tumor Suppressor Protein

2016
Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Cell Cycle Proteins; Cell Hypoxia; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; HeLa Cells; Humans; Hydroxylation; Models, Molecular; Neoplasms; Nuclear Proteins; Proline; Protein Interaction Maps; Proteomics; Transcription Factors

2016
Antigen retrieval prior to on-tissue digestion of formalin-fixed paraffin-embedded tumour tissue sections yields oxidation of proline residues.
    Biochimica et biophysica acta. Proteins and proteomics, 2017, Volume: 1865, Issue:7

    Topics: Antigens; Formaldehyde; Humans; Neoplasms; Oxidation-Reduction; Paraffin; Peptides; Proline; Protein Processing, Post-Translational; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2017
The metabolism of proline as microenvironmental stress substrate.
    The Journal of nutrition, 2008, Volume: 138, Issue:10

    Topics: Collagen; delta-1-Pyrroline-5-Carboxylate Reductase; Dietary Proteins; Food; Homeostasis; Humans; Inflammation; Neoplasms; Proline; Proline Oxidase; Pyrroline Carboxylate Reductases; Stress, Physiological

2008
cis-4-[(18)F]-Fluoro-l-proline fails to detect peripheral tumors in humans.
    Nuclear medicine and biology, 2008, Volume: 35, Issue:8

    Topics: Adult; Aged; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Neoplasms; Proline; Radionuclide Imaging

2008
Helix 3 is necessary and sufficient for prion protein's anti-Bax function.
    Journal of neurochemistry, 2009, Volume: 108, Issue:4

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cells, Cultured; Cytoprotection; Humans; Mice; Neoplasms; Nerve Degeneration; Prion Diseases; Proline; Protein Structure, Secondary; PrPC Proteins

2009
Shuttling gold nanoparticles into tumoral cells with an amphipathic proline-rich peptide.
    Chembiochem : a European journal of chemical biology, 2009, Apr-17, Volume: 10, Issue:6

    Topics: Biological Transport; Gold; HeLa Cells; Humans; Metal Nanoparticles; Microscopy; Neoplasms; Peptides; Proline

2009
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors

2010
Defective O-glycosylation due to a novel homozygous S129P mutation is associated with lack of fibroblast growth factor 23 secretion and tumoral calcinosis.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calcinosis; Carrier State; Chlorocebus aethiops; Codon; COS Cells; DNA Primers; Exons; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glycosylation; Homozygote; Humans; Hypophosphatemia, Familial; Molecular Sequence Data; Neoplasms; Polymorphism, Single Nucleotide; Proline; Serine

2009
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
    Oncology reports, 2010, Volume: 24, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate

2010
New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein.
    Annals of the New York Academy of Sciences, 2010, Volume: 1210

    Topics: Chromosome Mapping; Chromosomes, Human, Pair 3; Germ-Line Mutation; Humans; Kidney Neoplasms; Mutation; Neoplasms; Procollagen-Proline Dioxygenase; Proline; Succinate Dehydrogenase; Von Hippel-Lindau Tumor Suppressor Protein

2010
Production of anticancer polyenes through precursor-directed biosynthesis.
    Organic & biomolecular chemistry, 2011, Sep-21, Volume: 9, Issue:18

    Topics: Antineoplastic Agents; Fungi; HeLa Cells; Humans; Inhibitory Concentration 50; Neoplasms; Polyenes; Proline; Pyrones; Pyrroles

2011
The founder mutation MSH2*1906G-->C is an important cause of hereditary nonpolyposis colorectal cancer in the Ashkenazi Jewish population.
    American journal of human genetics, 2002, Volume: 71, Issue:6

    Topics: Alanine; Case-Control Studies; Chromosomes, Human, Pair 2; Colorectal Neoplasms, Hereditary Nonpolyposis; Crystallography, X-Ray; DNA-Binding Proteins; Female; Founder Effect; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Heterozygote; Humans; Israel; Jews; Male; Microsatellite Repeats; Mutation, Missense; MutS Homolog 2 Protein; Neoplasms; Pedigree; Point Mutation; Polymorphism, Genetic; Proline; Protein Conformation; Proto-Oncogene Proteins

2002
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.
    Nature genetics, 2003, Volume: 33, Issue:3

    Topics: Apoptosis; Arginine; Cell Line; Chaperonin 60; Codon; Fatty Acids, Unsaturated; Genes, p53; Genetic Variation; HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Mitochondria; Neoplasms; Polymorphism, Genetic; Proline; Suppression, Genetic; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin

2003
Identification of peptide substrates for human MMP-11 (stromelysin-3) using phage display.
    The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30

    Topics: Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Extracellular Matrix; Genetic Vectors; Humans; Kinetics; Matrix Metalloproteinase 11; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Models, Molecular; Neoplasms; Peptide Library; Peptides; Proline; Protein Binding; Protein Structure, Tertiary; Substrate Specificity

2003
Integrin beta3 Leu33Pro homozygosity and risk of cancer.
    Journal of the National Cancer Institute, 2003, Aug-06, Volume: 95, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Animals; Cytosine; Denmark; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Integrin beta3; Leucine; Male; Middle Aged; Neoplasm Invasiveness; Neoplasms; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Proline; Proportional Hazards Models; Prospective Studies; Registries; Risk Assessment; Risk Factors; Thymine

2003
The relation of ascorbic acid to the conversion of proline to hydroxyproline in the synthesis of collagen in the carrageenan granuloma.
    The Journal of biological chemistry, 1959, Volume: 234, Issue:1

    Topics: Ascorbic Acid; Carrageenan; Collagen; Encephalomyelitis; Granuloma; Hydroxyproline; Neoplasms; Proline; Vitamins

1959
[Autoradiographic studies on protein and melanin metabolism in different cell types in melanoma in mice (Harding-Passey type)].
    Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1962, Volume: 58

    Topics: Animals; Autoradiography; Dihydroxyphenylalanine; Melanins; Melanoma; Mice; Neoplasms; Neoplasms, Experimental; Proline; Proteins; Tyrosine

1962
PEPITASE ACTIVITIES IN TISSUES OF TUMOR-BEARING RATS.
    Cancer research, 1963, Volume: 23

    Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Erythrocytes; Glycine; Leucine; Liver; Liver Neoplasms; Muscles; Neoplasms; Neoplasms, Experimental; Peptide Hydrolases; Peptides; Proline; Rats; Research; Sarcoma; Sarcoma, Experimental

1963
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
    The Nebraska state medical journal, 1964, Volume: 49

    Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine

1964
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
    International journal of cancer, 2004, Volume: 109, Issue:1

    Topics: Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Camptothecin; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Male; Metalloporphyrins; Mice; Mitomycin; Neoplasms; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Polyethylene Glycols; Proline; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2004
p53-dependent down-regulation of telomerase is mediated by p21waf1.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: Base Sequence; Blotting, Southern; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p21; DNA; DNA Mutational Analysis; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; E2F1 Transcription Factor; Genes, Reporter; Histone Deacetylases; Humans; Luciferases; Molecular Sequence Data; Mutation; Neoplasms; Plasmids; Point Mutation; Proline; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Telomerase; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53

2004
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9

    Topics: Actins; Anaphase-Promoting Complex-Cyclosome; Antibodies, Monoclonal; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine; Lysine; Models, Molecular; Mutation; Mutation, Missense; Neoplasms; Peptides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Time Factors; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein

2005
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
    Cell cycle (Georgetown, Tex.), 2005, Volume: 4, Issue:9

    Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection

2005
A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
    Cancer cell, 2006, Volume: 9, Issue:4

    Topics: Animals; Apoptosis; Cells, Cultured; DNA; DNA Damage; Gene Expression Regulation, Neoplastic; Mice; Mice, Transgenic; Mutation; Neoplasms; Proline; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases

2006
Can mutations in gamma-actin modulate the toxicity of microtubule targeting agents?
    Journal of the National Cancer Institute, 2006, Oct-04, Volume: 98, Issue:19

    Topics: Actins; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leucine; Microtubules; Mutation; Neoplasms; Proline; RNA, Small Interfering; Tubulin; Tubulin Modulators; Valine; Vincristine

2006
Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression.
    Molecular and cellular biology, 2007, Volume: 27, Issue:4

    Topics: Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Conserved Sequence; DNA Damage; Fibroblasts; Gene Targeting; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mutant Proteins; Neoplasms; Point Mutation; Proline; Protein Binding; Protein Structure, Tertiary; Recombination, Genetic; Structure-Activity Relationship; Transcriptional Activation; Tumor Suppressor Protein p53

2007
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics.
    Bioorganic & medicinal chemistry letters, 2007, Apr-15, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Fibronectins; Humans; Inhibitory Concentration 50; Molecular Mimicry; Molecular Structure; Neoplasms; Oligopeptides; Peptide Library; Proline; Protein Conformation; Structure-Activity Relationship

2007
TP53 codon 72 polymorphism in 12 populations of insular Southeast Asia and Oceania.
    Journal of human genetics, 2007, Volume: 52, Issue:8

    Topics: Amino Acid Substitution; Arginine; Asia, Southeastern; Codon; Gene Frequency; Genetic Predisposition to Disease; Humans; Neoplasms; Oceania; Polymorphism, Genetic; Population; Proline; Tumor Suppressor Protein p53

2007
Introduction to second proline symposium.
    Amino acids, 2008, Volume: 35, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Gene Expression Regulation, Neoplastic; Humans; Metabolism; Models, Biological; Neoplasms; Neurophysiology; Ornithine-Oxo-Acid Transaminase; Proline

2008
Preclinical evaluation of 4-[18F]fluoroprolines: diastereomeric effect on metabolism and uptake in mice.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:3

    Topics: Animals; Bone Neoplasms; Collagen; Fluorine Radioisotopes; Half-Life; Humans; Kidney; Liver; Mice; Neoplasms; Neoplasms, Experimental; Osteosarcoma; Proline; Radionuclide Imaging; Radiopharmaceuticals; Stereoisomerism; Tissue Distribution

1999
Molecular cloning and characterization of the tumor transforming gene (TUTR1): a novel gene in human tumorigenesis.
    Cytogenetics and cell genetics, 1999, Volume: 84, Issue:3-4

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cloning, Molecular; Expressed Sequence Tags; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Organ Specificity; Phosphoproteins; Proline; RNA, Messenger; Securin; Testis; Transfection; Tumor Cells, Cultured

1999
Nuclear DEAF-1-related (NUDR) protein contains a novel DNA binding domain and represses transcription of the heterogeneous nuclear ribonucleoprotein A2/B1 promoter.
    The Journal of biological chemistry, 1999, Oct-22, Volume: 274, Issue:43

    Topics: 5' Untranslated Regions; Base Sequence; Binding Sites; DNA-Binding Proteins; Gene Expression Regulation; Helix-Loop-Helix Motifs; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Proline; Promoter Regions, Genetic; Repressor Proteins; Thymidine Kinase; Transcription Factors; Transcription, Genetic

1999
DNA sequence variants of p53: cancer and aging.
    American journal of human genetics, 1999, Volume: 65, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline

1999
[The lymphocyte cytotoxicity test in tumor immunology (author's transl)].
    Klinische Wochenschrift, 1975, Volume: 53, Issue:1

    Topics: Animals; Antigens, Neoplasm; B-Lymphocytes; Cells, Cultured; Chromium Radioisotopes; Culture Media; Cytological Techniques; Cytotoxicity Tests, Immunologic; Epitopes; False Positive Reactions; Humans; Immunity, Cellular; Immunologic Techniques; Lymphocytes; Melanoma; Mice; Mitosis; Neoplasms; Proline; Rabbits; Rats; Surface Properties; T-Lymphocytes; Thymidine; Tritium; Urinary Bladder Neoplasms

1975
Proline-hydroxylase activity in human blood.
    Lancet (London, England), 1970, Jan-17, Volume: 1, Issue:7638

    Topics: Adolescent; Adult; Aged; Anesthesia; Bone Diseases; Child; Circadian Rhythm; Collagen; Collagen Diseases; Female; Humans; Liver Diseases; Male; Middle Aged; Mixed Function Oxygenases; Neoplasms; Proline; Surgical Procedures, Operative

1970
[Comparative autoradiographic and quantitative radiochemical studies on the same material].
    Acta histochemica, 1968

    Topics: Anabolic Agents; Animals; Arteriosclerosis; Autoradiography; Carbon Isotopes; Connective Tissue; Connective Tissue Cells; Cyclophosphamide; Fractures, Bone; Glycosaminoglycans; Hydrocortisone; Mice; Neoplasms; Proline; Radiochemistry; Radiometry; Rats; Regeneration; Sulfates; Sulfur Isotopes; Thymidine; Tritium; Wound Healing; Wounds and Injuries

1968
[Metabolism of glycosaminoglycane, collagen, and kidney function in dermatomyositis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1974, Volume: 25, Issue:7

    Topics: Autoradiography; Blood Proteins; Collagen; Dermatomyositis; Female; Glomerular Filtration Rate; Glucosamine; Glycosaminoglycans; Hexosamines; Histocytochemistry; Humans; Hydroxyproline; In Vitro Techniques; Kidney; Male; Neoplasms; Proline; Skin; Sulfates; Sulfur Radioisotopes; Tritium

1974
Relationship between exposure to asbestos, collagen formation, ferruginous bodies, and carcinoma.
    American Industrial Hygiene Association journal, 1974, Volume: 35, Issue:11

    Topics: Asbestos; Benzopyrenes; Carcinogens; Cell Membrane Permeability; Citric Acid Cycle; Collagen; Electron Transport; Energy Metabolism; Environmental Exposure; Humans; Hydroxylation; Iron; Ketoglutaric Acids; Macrophages; Magnesium; Metalloproteins; Neoplasms; Oxygen Consumption; Phagocytosis; Procollagen-Proline Dioxygenase; Proline; Protein Binding

1974
Problems of in-vitro incubation with radioactive precursors.
    Folia morphologica, 1973, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Agents; Cytidine; Humans; Neoplasms; Phenylalanine; Proline; Rats; Thymidine; Tritium

1973
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
    Strahlentherapie, 1972, Volume: 143, Issue:4

    Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine

1972