Compounds > proline

proline and Auricular Fibrillation

proline has been researched along with Auricular Fibrillation in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alimardanov, A; Butera, JA; Di, L; Hennan, JK; Huselton, C; Kerns, E; Larsen, BD; Liu, K; McDonald, L; Morgan, GA; Petersen, JS; Rossman, EI; Swillo, RE; Unwalla, R; Wang, Q1
Butera, J; Feldman, HS; Gardell, SJ; Gruver, M; Haugan, K; Hennan, JK; Kantrowitz, J; Krueger, JA; Liu, K; Morgan, GA; Petersen, JS; Rossman, EI; Swillo, RE1
Butera, JA; Di, L; Hennan, JK; Huselton, C; Larsen, BD; Morgan, GA; Piatnitski Chekler, EL; Rossman, EI; Swillo, RE1
Dorian, P; Hennan, JK; Hu, X; Laurent, G; Leong-Poi, H; Mangat, I; Moe, GW; Ramadeen, A; Rossman, EI; So, PP; Tarulli, E1

Other Studies

4 other study(ies) available for proline and Auricular Fibrillation

ArticleYear
Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.
    Journal of medicinal chemistry, 2009, Feb-26, Volume: 52, Issue:4

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzamides; Dipeptides; Disease Models, Animal; Drug Discovery; Gap Junctions; Mice; Peptide Library; Proline; Structure-Activity Relationship

2009
The gap junction modifier, GAP-134 [(2S,4R)-1-(2-aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic acid], improves conduction and reduces atrial fibrillation/flutter in the canine sterile pericarditis model.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Benzamides; Connexin 43; Dipeptides; Disease Models, Animal; Dogs; Electric Conductivity; Female; Gap Junctions; Heart Atria; Heart Conduction System; Male; Molecular Structure; Oligopeptides; Pericarditis; Postoperative Complications; Proline; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological

2009
Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Benzamides; Disease Models, Animal; Dogs; Drug Discovery; Gap Junctions; Mice; Proline; Rats; Structure-Activity Relationship; Tachycardia, Ventricular

2009
Effects of chronic gap junction conduction-enhancing antiarrhythmic peptide GAP-134 administration on experimental atrial fibrillation in dogs.
    Circulation. Arrhythmia and electrophysiology, 2009, Volume: 2, Issue:2

    Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzamides; Cardiac Pacing, Artificial; Connexin 43; Disease Models, Animal; Dogs; Fibrosis; Gap Junctions; Heart Atria; Heart Conduction System; Immunohistochemistry; Proline; Refractory Period, Electrophysiological

2009