proline has been researched along with Anoxemia in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (28.30) | 18.7374 |
| 1990's | 2 (3.77) | 18.2507 |
| 2000's | 19 (35.85) | 29.6817 |
| 2010's | 9 (16.98) | 24.3611 |
| 2020's | 8 (15.09) | 2.80 |
| Authors | Studies |
|---|---|
| Li, B; Li, L; Meng, J; Wang, T; Zhang, G | 1 |
| Germán-Acacio, JM; Gómez-Martín, D; Maravillas-Montero, JL; Mejía-Domínguez, NR; Páez-Franco, JC; Pérez-Fragoso, A; Ponce-de-León, A; Tamez-Torres, KM; Torres-Ruiz, J; Ulloa-Aguirre, A | 1 |
| Chen, T; Chu, Y; Fang, K; Leng, Z; Li, Z; Sun, M; Xu, A; Xu, M; Zhang, L; Zhang, Y; Zhang, Z; Zhao, Z | 1 |
| Babuta, M; Dai, X; Dang, F; Duan, LJ; Erickson, E; Fong, GH; Guan, D; Guo, R; Hu, J; Inuzuka, H; Jiang, C; Kaelin, WG; Karnoub, AE; Lee, YR; Lian, G; Liu, H; Liu, J; Liu, M; Lv, M; Meng, H; Miao, J; Pan, L; Shi, L; Szabo, G; Tu, Z; Wang, H; Wang, J; Wang, M; Wang, Y; Wei, W; Xie, X; Xu, D; Yan, P; Yu, W; Yuan, J; Zhang, T; Zhang, Z; Zhuang, Y | 1 |
| Liang, H; Song, K | 1 |
| Gao, Y; Guo, Y; Liu, Y; Lu, F; Piao, Y; Tan, S; Tang, Y | 1 |
| Hua, C; Lin, J; Lv, Q; Shen, Z; Song, Y; Wang, J; Wang, M; Xue, Z; Ying, H; Zhou, B | 1 |
| He, W; Hu, S; Wu, G | 1 |
| Al-Ejeh, F; Brennan, DJ; Casciello, F; Gannon, F; Hill, MM; Kelly, G; Lee, JS; Ngiow, SF; Smyth, MJ; Stoll, T; Windloch, K; Young, A | 1 |
| Clasen, SJ; Espenshade, PJ; Gu, H; Shao, W | 1 |
| Fang, C; Gao, P; Geng, P; Guo, L; Hu, C; Li, E; Liu, Y; Sun, M; Tang, L; Wang, C; Wang, J; Wang, Y; Xu, G; Yin, P; Yu, J; Zeng, J; Zhuang, Z | 1 |
| Cao, J; Li, X; Wang, J; Xiao, F | 1 |
| Catrina, SB; Chatzidionysiou, K; Ekberg, NR; Eliasson, S; Falhammar, H; Gu, HF; Li, YW; Zheng, X | 1 |
| Chesler, N; Hacker, T; Schreier, D; Song, G | 1 |
| Abboud, MI; Cantrelle, FX; Chowdhury, R; Claridge, TD; Domene, C; Ge, W; Hardy, AP; Landrieu, I; Leung, IK; Pugh, CW; Ratcliffe, PJ; Schofield, CJ; Tian, YM | 1 |
| Ahn, YS; Kim, CH; Kim, DG; Kim, HS; Kim, I; Lee, J; Seo, GH | 1 |
| Amadori, D; Bonafe, M; Brigliadori, G; Fabbri, F; Gusolfino, D; Massa, I; Passardi, A; Ricci, M; Rosetti, M; Sansone, P; Storci, G; Tesei, A; Ulivi, P; Vannini, I; Zoli, W | 1 |
| Chowdhury, R; Domene, C; Flashman, E; Hewitson, KS; Loenarz, C; McDonough, MA; Mecinović, J; Schofield, CJ | 1 |
| Kalamaki, MS; Kanellis, AK; Merkouropoulos, G | 1 |
| Du, L; Lin, R; Liu, Q; Meng, K; Pan, C; Wu, W; Zhao, L | 1 |
| Chen, P; Dong, Q; Feng, J; Lan, A; Wang, C; Wang, X; Yang, C; Yang, Z; Zeng, F; Zhang, M | 1 |
| Maxwell, PH; Mole, DR; Pugh, CW; Ratcliffe, PJ | 1 |
| Chan, DA; Denko, NC; Giaccia, AJ; Sutphin, PD | 1 |
| D'Angelo, G; Duplan, E; Frelin, C; Vigne, P | 1 |
| Gorman, JJ; Lando, D; Peet, DJ; Whitelaw, ML | 1 |
| Boyer, N; D'Angelo, G; Duplan, E; Frelin, C; Vigne, P | 1 |
| Günzler, V; Hirsilä, M; Kivirikko, KI; Koivunen, P; Myllyharju, J | 1 |
| Nikinmaa, M; Pursiheimo, S; Soitamo, AJ | 1 |
| Bruick, RK; Donald, SP; Kasprzak, KS; Phang, JM; Salnikow, K; Zhitkovich, A | 1 |
| Kentsis, A; Miller, F; Osman, R; Pan, ZQ | 1 |
| Hirota, K; Kasuno, K; Kimura, H; Kurooka, H; Li, X; Okada, T; Torii, K; Yokota, Y; Yoshida, H | 1 |
| Belinka, B; Lu, SE; Pachence, J; Poiani, GJ; Riley, DJ; Simon, PM; Tozzi, CA | 1 |
| Graf, AV; Krushinskaya, YV; Maklakova, AS; Sokolova, NA | 1 |
| Clancy, J; Klein, RM; McKenzie, JC | 1 |
| Catravas, JD; Gillis, CN | 1 |
| Herrig, JE; McWeeny, OJ; Robillard, JE; Weismann, DN | 1 |
| Kato, S; Kawai, H; Matsuoka, M; Mochizuki, J; Odagawa, A; Shindo, K | 1 |
| Burton, CJ; Combe, C; Dufourco, P; Harris, KP; Horsburgh, T; Walls, J; Weston, S | 1 |
| Asahara, T; Maulik, N; Otani, H; Ray, PS; Sasaki, H; Zhu, L | 1 |
| Chang, NS | 1 |
| Kaelin, WG | 1 |
| Hurych, J; Mirejovská, E; Mirejovský, P | 1 |
| Hurych, J; Mirejovská, E; Ostádal, B; Pelouch, V; Procházka, J | 1 |
| Anttinen, H; Kivirikko, KI; Oikarinen, A | 1 |
| Romen, W | 1 |
| Gregson, N; Hamberger, A; Lehninger, AL | 1 |
| Prockop, DJ; Uitto, J | 2 |
| Wajgt, A; Wender, M; Zgorzalewicz, B | 1 |
| Lindy, S; Pedersen, FB; Turto, H; Uitto, J | 1 |
| Beaty, C; Becker, B; Coben, LA; Cotlier, E | 1 |
| Baerlocher, KE; Mohyuddin, F; Scriver, CR | 1 |
| Chvapil, M; Hurych, J; Mirejovská, E | 1 |
4 review(s) available for proline and Anoxemia
| Article | Year |
|---|---|
Hydroxyproline in animal metabolism, nutrition, and cell signaling.
Topics: Animals; Collagen; Dietary Proteins; Hydroxyproline; Hypoxia; Proline; Signal Transduction | 2022 |
Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation.
Topics: Asparagine; Hydroxylation; Hypoxia; Oxygen; Proline; Transcription Factors | 2003 |
How oxygen makes its presence felt.
Topics: Animals; Asparagine; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Models, Biological; Nuclear Proteins; Oxygen; Proline; Protein Structure, Tertiary; Transcription Factors; Transcriptional Activation | 2002 |
[On the pathogenesis of the glomerulosclerosis ultrastructural and autoradiographic investigations on the rat kidney (author's transl)].
Topics: Aging; Animals; Autoradiography; Basement Membrane; Collagen; Hemostasis; Hypertension; Hypoxia; Kidney Glomerulus; Ligation; Male; Morpholines; Nephrectomy; Nitroso Compounds; Proline; Rats; Renal Veins | 1976 |
49 other study(ies) available for proline and Anoxemia
| Article | Year |
|---|---|
Oxygen sensing and transcriptional regulation under hypoxia exposure in the mollusk Crassostrea gigas.
Topics: Amino Acids; Animals; Crassostrea; Hypoxia; Oxygen; Phylogeny; Procollagen-Proline Dioxygenase; Proline; RNA, Messenger | 2022 |
Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology.
Topics: Amino Acids; COVID-19; Cystine; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Homeostasis; Humans; Hypoxia; Male; Oxidation-Reduction; Oxygen; Proline; Reactive Oxygen Species; SARS-CoV-2 | 2022 |
Targeting IGF1R signaling enhances the sensitivity of cisplatin by inhibiting proline and arginine metabolism in oesophageal squamous cell carcinoma under hypoxia.
Topics: Arginine; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Hypoxia; Oxygen; Proline; Receptor, IGF Type 1; Tumor Microenvironment | 2023 |
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Topics: Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Necroptosis; Proline; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I | 2023 |
Comprehensive metabolomics and transcriptomics analysis reveals protein and amino acid metabolic characteristics in liver tissue under chronic hypoxia.
Topics: Amino Acids; Animals; Hypoxia; Liver; Mice; Proline; Transcriptome | 2023 |
Metabolomic changes of blood plasma associated with two phases of rat OIR.
Topics: Animals; Animals, Newborn; Biomarkers; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutamine; Hyperoxia; Hypoxia; Metabolome; Metabolomics; Ornithine; Oxidative Stress; Oxygen; Proline; Rats; Rats, Sprague-Dawley; Retinal Neovascularization; Retinopathy of Prematurity | 2020 |
Metabolomic Analysis of the Ameliorative Effect of Enhanced Proline Metabolism on Hypoxia-Induced Injury in Cardiomyocytes.
Topics: Animals; Apoptosis; Hypoxia; Membrane Potential, Mitochondrial; Metabolomics; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Proline; Rats; Reactive Oxygen Species; Signal Transduction | 2020 |
G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease-Free Survival; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Hypoxia; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred C57BL; Prognosis; Proline; Protein Processing, Post-Translational; Recurrence; RNA, Small Interfering; Tumor Microenvironment | 2017 |
Prolyl dihydroxylation of unassembled uS12/Rps23 regulates fungal hypoxic adaptation.
Topics: Adaptation, Physiological; Gene Expression Regulation, Fungal; Hydroxylation; Hypoxia; Proline; Protein Binding; Protein Interaction Mapping; Schizosaccharomyces; Schizosaccharomyces pombe Proteins | 2017 |
Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Energy Metabolism; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Metabolome; Metabolomics; Phenotype; Proline; Sorafenib; Xenograft Model Antitumor Assays | 2018 |
Mechanisms of vascular endothelial cell injury in response to intermittent and/or continuous hypoxia exposure and protective effects of anti-inflammatory and anti-oxidant agents.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Coculture Techniques; Cyclic N-Oxides; Endothelial Cells; Humans; Hypoxia; Inflammation Mediators; Neutrophils; Oxidative Stress; Proline; Spin Labels; Thiocarbamates | 2019 |
Protective Effect of the
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Genotype; Glucose; HEK293 Cells; Humans; Hyperglycemia; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Proline; Risk Factors; Serine; Transcriptional Activation; Young Adult | 2019 |
The role of collagen synthesis in ventricular and vascular adaptation to hypoxic pulmonary hypertension.
Topics: Adaptation, Physiological; Air; Animals; Blood Gas Analysis; Blood Vessels; Collagen; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Mice; Mice, Inbred C57BL; Proline | 2013 |
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Fibroblasts; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia-Inducible Factor-Proline Dioxygenases; Isoenzymes; Mice; Molecular Dynamics Simulation; Neoplasms; Oxygen; Polycythemia; Proline; Protein Binding; Protein Domains; Recombinant Proteins; Structure-Activity Relationship | 2016 |
Inhibitory effect of zinc on hypoxic HIF-1 activation in astrocytes.
Topics: Antineoplastic Agents; Astrocytoma; Cell Line, Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Proline; Protein Transport; Thiocarbamates; Time Factors; Zinc Sulfate | 2008 |
Role of p53 codon 72 arginine allele in cell survival in vitro and in the clinical outcome of patients with advanced breast cancer.
Topics: Adult; Aged; Alleles; Arginine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Codon; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Kaplan-Meier Estimate; Middle Aged; Neoplasm Proteins; Polymorphism, Single Nucleotide; Proline; Transfection; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Topics: Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Humans; Hydroxylation; Hydroxyproline; Hypoxia; Hypoxia-Inducible Factor 1; Ketoglutaric Acids; Models, Molecular; Oxygen; Procollagen-Proline Dioxygenase; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Signal Transduction; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2009 |
Can ornithine accumulation modulate abiotic stress tolerance in Arabidopsis?
Topics: Adaptation, Physiological; Amino-Acid N-Acetyltransferase; Arabidopsis; Arginine; Gene Expression; Genes, Plant; Hypoxia; Ornithine; Oxygen; Plants, Genetically Modified; Polyamines; Proline; Solanum lycopersicum; Stress, Physiological | 2009 |
Hypoxia activates heparanase expression in an NF-kappaB dependent manner.
Topics: Antioxidants; Disease Progression; Enzyme Activation; Extracellular Matrix; Glucuronidase; Hypoxia; Matrix Metalloproteinase 9; Neoplasm Invasiveness; NF-kappa B; Oligonucleotides, Antisense; Oxygen; Proline; RNA, Messenger; Thiocarbamates; Time Factors | 2010 |
Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.
Topics: Blotting, Western; Cell Line, Tumor; Cell Survival; Cobalt; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Hydrogen Sulfide; Hypoxia; Interleukin-1beta; Interleukin-6; Interleukin-8; NF-kappa B; Nitrobenzenes; Proline; Reactive Oxygen Species; Signal Transduction; Sulfonamides; Thiocarbamates | 2011 |
Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cobalt; Dose-Response Relationship, Drug; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Ketoglutaric Acids; Ligases; Oxygen; Plasmids; Proline; Protein Biosynthesis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reticulocytes; Time Factors; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2002 |
Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.
Topics: Amino Acids, Dicarboxylic; Animals; Chelating Agents; Cobalt; Deferoxamine; Fibroblasts; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Iron; Luciferases; Mice; Mice, Knockout; Proline; Protein Binding; Transcription Factors; Transfection | 2002 |
Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation.
Topics: Adaptation, Physiological; Animals; Cyclosporine; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Procollagen-Proline Dioxygenase; Proline; Rats; Transcription Factors; Transcription, Genetic | 2003 |
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
Topics: Animals; Blotting, Northern; Blotting, Western; DNA-Binding Proteins; Down-Regulation; Feedback, Physiological; Glutathione Transferase; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Ketoglutaric Acids; Ligases; Molecular Sequence Data; Nuclear Proteins; Oxygen; Peptides; Procollagen-Proline Dioxygenase; Proline; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Succinic Acid; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein | 2003 |
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Topics: Animals; Binding Sites; Catalysis; Cell Line; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitory Concentration 50; Insecta; Ketoglutaric Acids; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Nuclear Proteins; Oxygen; Peptides; Procollagen-Proline Dioxygenase; Proline; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Repressor Proteins; Time Factors; Trans-Activators; Transcription Factors | 2004 |
Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells.
Topics: Acetylcysteine; Animals; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Cell Line; Cysteine; Dimerization; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Immunoprecipitation; Oncorhynchus mykiss; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Proline; Propyl Gallate; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; RNA; Time Factors; Transcription Factors; Transcriptional Activation | 2004 |
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
Topics: Ascorbic Acid; Blotting, Western; Carcinogens; Cell Line; Chromatography, High Pressure Liquid; Cobalt; Cysteine Endopeptidases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Ketoglutaric Acids; Models, Biological; Multienzyme Complexes; Mutation; Nickel; Nuclear Proteins; Oxygen; Plasmids; Procollagen-Proline Dioxygenase; Proline; Proteasome Endopeptidase Complex; Protein Structure, Tertiary; Time Factors; Transcription Factors; Transcription, Genetic; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein | 2004 |
Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
Topics: Actins; Anaphase-Promoting Complex-Cyclosome; Antibodies, Monoclonal; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Hydroxylation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leucine; Lysine; Models, Molecular; Mutation; Mutation, Missense; Neoplasms; Peptides; Plasmids; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Time Factors; Trans-Activators; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligase Complexes; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein | 2005 |
Synergistic effect of hypoxia and TNF-alpha on production of PAI-1 in human proximal renal tubular cells.
Topics: Antineoplastic Agents; Cell Nucleus; Cell Survival; Cells, Cultured; Drug Synergism; Gene Expression Regulation; Genistein; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Tubules, Proximal; NF-kappa B; Oxygen; Plasminogen Activator Inhibitor 1; Proline; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Signal Transduction; Thiocarbamates; Transcription Factors; Tumor Necrosis Factor-alpha | 2005 |
Prodrug of proline analogue reduces hypoxic pulmonary hypertension in rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hydroxyproline; Hypertension, Pulmonary; Hypoxia; Infusion Pumps; Injections, Intravenous; Injections, Spinal; Injections, Subcutaneous; Lysine; Male; Polyethylene Glycols; Prodrugs; Proline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome | 2006 |
Peptidergic correction of behavior in adult progeny of albino rats exposed to acute hypoxia during early organogenesis.
Topics: Animals; Female; Hypoxia; Male; Mental Disorders; Oligopeptides; Pregnancy; Prenatal Exposure Delayed Effects; Proline; Rats; Risk-Taking | 2006 |
Autoradiographic analysis of cell proliferation and protein synthesis in the pulmonary trunk of rats during the early development of hypoxia-induced pulmonary hypertension.
Topics: Animals; Autoradiography; Cardiomegaly; Cell Division; Hypertension, Pulmonary; Hypoxia; Male; Organ Size; Proline; Protein Biosynthesis; Pulmonary Artery; Rats; Rats, Inbred Strains; Tritium | 1984 |
Metabolism of [3H]benzoyl-phenylalanyl-alanyl-proline by pulmonary angiotensin converting enzyme in vivo: effects of bradykinin, SQ 14225 or acute hypoxia.
Topics: Animals; Bradykinin; Captopril; Dogs; Female; Hypoxia; In Vitro Techniques; Lung; Male; Oligopeptides; Peptidyl-Dipeptidase A; Proline; Rabbits | 1981 |
Organ tissue blood flow responses to hypoxemia in lambs: effect of angiotensin converting enzyme inhibitor.
Topics: Adrenal Glands; Animals; Blood Circulation; Blood Pressure; Captopril; Coronary Circulation; Heart Rate; Hypoxia; Intestine, Small; Liver Circulation; Muscles; Proline; Regional Blood Flow; Renin-Angiotensin System; Sheep; Spleen | 1983 |
Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties.
Topics: Animals; Brain; Fermentation; Hypoxia; Lipid Peroxidation; Male; Mice; Proline; Pyrroles; Rats; Rats, Wistar; Streptomyces | 1993 |
Hypoxia induces intercellular adhesion molecule-1 on cultured human tubular cells.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Cytokines; Humans; Hypoxia; Intercellular Adhesion Molecule-1; Kidney Tubules; Oxygen; Proline; Thiocarbamates | 1997 |
Hypoxia/reoxygenation promotes myocardial angiogenesis via an NF kappa B-dependent mechanism in a rat model of chronic myocardial infarction.
Topics: Animals; Antioxidants; Apoptosis; Arteries; Blood Pressure; Capillaries; Coronary Vessels; Dobutamine; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Hypoxia; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NF-kappa B; Oxidation-Reduction; Oxygen; Proline; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thiocarbamates; Time Factors | 2001 |
The non-ankyrin C terminus of Ikappa Balpha physically interacts with p53 in vivo and dissociates in response to apoptotic stress, hypoxia, DNA damage, and transforming growth factor-beta 1-mediated growth suppression.
Topics: Animals; Ankyrins; Apoptosis; Cell Division; Cell Line; Cell Nucleus; COS Cells; Cytosol; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Dominant; Humans; Hyaluronoglucosaminidase; Hypoxia; I-kappa B Proteins; Liver; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Spleen; Staurosporine; Threonine; Time Factors; Transfection; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 2002 |
Effect of hyperbarism on collagenous protein metabolism in granulation tissue.
Topics: Animals; Atmospheric Pressure; Collagen; Granulation Tissue; Hydroxyproline; Hyperbaric Oxygenation; Hypoxia; Proline; Protein Biosynthesis; Rats | 1975 |
Effect of intermittent high altitude hypoxia on the synthesis of collagenous and non-collagenous proteins of the right and left ventricular myocardium.
Topics: Altitude Sickness; Animals; Cardiomegaly; Collagen; Heart Ventricles; Hypoxia; Male; Myocardium; Proline; Protein Biosynthesis; Proteins; Rats | 1978 |
Further studies on the effect of the collagen triple-helix formation on the hydroxylation of lysine and the glycosylations of hydroxylysine in chick-embryo tendon and cartilage cells.
Topics: Animals; Cartilage; Chick Embryo; Collagen; Dithiothreitol; Hydroxylation; Hydroxylysine; Hydroxyproline; Hypoxia; Lysine; Proline; Tendons | 1977 |
The effect of acute exercise on amino acid incorporation into mitochondria of rabbit tissues.
Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; Aging; Amino Acids; Animals; Brain; Buffers; Carbon Isotopes; Centrifugation, Density Gradient; Hypoxia; Leucine; Male; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxygen; Physical Exertion; Proline; Protein Biosynthesis; Quaternary Ammonium Compounds; Rabbits; Swimming; Testosterone | 1969 |
Biosynthesis of cartilage procollagen. Influence of chain association and hydroxylation of prolyl residues on the folding of the polypeptides into the triple-helical conformation.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Cartilage; Chick Embryo; Chromatography, Gel; Collagen; Disulfides; Electrophoresis, Polyacrylamide Gel; Hydroxyproline; Hypoxia; Iodoacetates; Isotope Labeling; Kinetics; Microbial Collagenase; Proline; Protein Binding; Protein Conformation; Protein Precursors; Time Factors; Trypsin | 1974 |
Protein synthesis in vitro by the rat brain in course of experimental cyanide encephalopathy.
Topics: Animals; Brain; Brain Diseases; Cyanides; Demyelinating Diseases; Disease Models, Animal; Female; Hypoxia; Leucine; Male; Myelin Sheath; Nerve Tissue Proteins; Poisoning; Proline; Rats | 1974 |
Synthesis and secretion of under-hydroxylated procollagen at various temperatures by cells subject to temporary anoxia.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Chick Embryo; Chromatography, Gel; Collagen; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Hydroxylysine; Hypoxia; Isotope Labeling; Lysine; Mixed Function Oxygenases; Nitrogen; Proline; Protein Conformation; Protein Precursors; Temperature; Tendons; Time Factors | 1974 |
Lactate, lactate dehydrogenase and protocollagen proline hydroxylase in rat skin autograft.
Topics: Animals; Collagen; Hypoxia; L-Lactate Dehydrogenase; Lactates; Male; Mixed Function Oxygenases; Proline; Rats; RNA; Skin Transplantation; Transplantation, Autologous | 1971 |
Transport of amino acids by rabbit choroid plexus in vitro.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Carrier Proteins; Choroid Plexus; Cold Temperature; Cyanides; Diffusion; Dinitrophenols; Glycine; Hydrogen-Ion Concentration; Hypoxia; Mathematics; Organ Culture Techniques; Ouabain; Proline; Rabbits; Sodium | 1971 |
The ontogeny of amino acid transport in rat kidney. II. Kinetics of uptake and effect of anoxia.
Topics: Aminoisobutyric Acids; Animals; Animals, Newborn; Biological Transport; Carbon Isotopes; Cyanides; Depression, Chemical; Glycine; Hypoxia; Kidney; Kinetics; Proline; Rats; Stimulation, Chemical; Temperature | 1971 |
Effect of long-term hypoxia on protein synthesis in granuloma and in some organs in rats.
Topics: Animals; Carbon Isotopes; Collagen; Female; Granuloma; Hydroxyproline; Hypoxia; Intestine, Small; Liver; Lung; Myocardium; Proline; Protein Biosynthesis; Rats | 1970 |