proline and Alloxan Diabetes

proline has been researched along with Alloxan Diabetes in 46 studies

Research

Studies (46)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (71.74)	18.7374
1990's	6 (13.04)	18.2507
2000's	4 (8.70)	29.6817
2010's	1 (2.17)	24.3611
2020's	2 (4.35)	2.80

Authors

Authors	Studies
Chen, F; Liao, J; Lu, Q; Niu, C; Wang, H; Wang, S; Yu, Y	1
Mesgari-Abbasi, M; Mirzakhani, N; Vahdatpour, T; Valizadeh, H	1
Gudascheva, TA; Ivanova, EA; Kapitsa, IG; Ostrovskaya, RU; Ozerova, IV; Seredenin, SB; Voronina, TA	1
Arai, T; Hara, K; Kameno, M; Kishi, M; Kurohara, M; Moriyama, H; Nagata, M; Okumachi, Y; Yamada, K; Yasuda, H; Yokono, K	1
Larkin, D; Merfert, MG; Moon, SE; Perone, P; Stevens, MJ; Varani, J	1
BEGIN, N; SCHOLEFIELD, PG	1
EICHHORN, JH; SNIFFEN, RC	1
CASTLES, JJ; MOYER, AN; WOOL, IG	1
Gilbert, RE; Kelly, DJ; Mifsud, S; Pollock, CA; Qi, W; Wilkinson-Berka, JL; Zhang, Y	1
Mayer, JH; McLean, WG; Tomlinson, DR	1
Gechter, F; Hasslacher, C; Reichenbacher, R; Timpl, R	1
Cohen, MP; Surma, ML; Wu, VY	1
Bürklin, E; Gechter, F; Hasslacher, C; Kopischke, HG; Reichenbacher, R	1
Cohen, MP; Dasmahapatra, A; Wu, VY	1
Modrak, J	1
Biber, J; Hsiao, SC; Kempson, SA; Murer, H; Seifert, SA	1
Han, DC; Hoffman, BB; Isono, M; Mogyorósi, A; Ziyadeh, FN	1
Hilf, R; Hissin, PJ	2
Bowersox, J; Edlin-Folz, E; Golub, L; Murray, J; Ramamurthy, N; Schneir, M; Yavelow, J	1
Brownlee, M; Spiro, RG	1
Kern, P; Moczar, M; Robert, L	1
Arquilla, ER; Nakajo, M; Weringer, EJ	1
Anderson, S; Brenner, BM; Rennke, HG	1
Golub, LM; Ramamurthy, NS; Sasaki, T; Yu, Z	1
Golub, LM; Ramamurthy, NS; Sasaki, T	2
Golub, LM; Kaneko, H; Ramamurthy, NS; Sasaki, T	1
Jakobsen, J; Sidenius, P	1
Reddi, AS	3
Spanheimer, RG; Umpierrez, GE; Zlatev, T	1
Goldstein, S; Phillips, LS; Spanheimer, RG; Umpierrez, GE	1
Golub, L; Imberman, M; Ramamurthy, N; Schneir, M	2
Delbridge, L; Marsh, M; McLennan, S; Reeve, T; Spaliviero, J; Swanson, B; Turtle, JR; Yue, DK	1
Ofulue, AF; Thurlbeck, WM	1
Debnam, ES; Karasov, WH; Thompson, CS	1
Folkes, GA; Golub, LM; Leung, MK; Ramamurthy, NS; Schneir, M	1
Golub, L; Ramamurthy, N; Schneir, M	1
Brown, RG; Liddy, EP	1
Lal, D; Schedl, HP	1
Inoue, H; Kasper, CB; Pitot, HC	1
Gullander, S; Rucker, RB; Yep, P	1
Fang, VS	1

Reviews

1 review(s) available for proline and Alloxan Diabetes

Article	Year
Axonal transport in experimental diabetes. Clinical physiology (Oxford, England), 1985, Volume: 5 Suppl 5 Topics: Acetylcholinesterase; Actins; Animals; Axonal Transport; Blood Glucose; Choline O-Acetyltransferase; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glycoproteins; Intermediate Filaments; Kinetics; Male; Proline; Rats; Rats, Inbred Strains; Tubulin	1985

Other Studies

45 other study(ies) available for proline and Alloxan Diabetes

Article	Year
Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats. Food & function, 2022, Jun-20, Volume: 13, Issue:12 Topics: Amino Sugars; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Metabolomics; Nucleotides; Proline; Quinazolines; Rats; Streptozocin; Tryptophan	2022
Protective effects of di- and tri-peptides containing proline, glycine, and leucine on liver enzymology and histopathology of diabetic mice. Archives of physiology and biochemistry, 2022, Volume: 128, Issue:1 Topics: Amino Acid Sequence; Animals; Diabetes Mellitus, Experimental; Glycine; Leucine; Liver; Mice; Peptides; Proline	2022
Comparative activity of proline-containing dipeptide noopept and inhibitor of dipeptidyl peptidase-4 sitagliptin in a rat model of developing diabetes. Bulletin of experimental biology and medicine, 2014, Volume: 156, Issue:3 Topics: Animals; Diabetes Mellitus, Experimental; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Proline; Pyrazines; Rats; Rats, Wistar; Sitagliptin Phosphate; Triazoles	2014
One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide. Biochemical and biophysical research communications, 2008, Sep-26, Volume: 374, Issue:3 Topics: Amino Acid Sequence; Animals; CD4 Antigens; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Immunoglobulin G; Immunosuppression Therapy; Injections, Intravenous; Insulin; Mice; Mice, Inbred NOD; Peptide Fragments; Proline; Serine; T-Lymphocytes, Regulatory; Th1 Cells	2008
All-trans retinoic acid improves structure and function of diabetic rat skin in organ culture. Diabetes, 2002, Volume: 51, Issue:12 Topics: Animals; Blood Glucose; Cell Division; Collagen; Diabetes Mellitus, Experimental; Fibroblasts; Keratolytic Agents; Male; Matrix Metalloproteinases; Organ Culture Techniques; Proline; Rats; Rats, Wistar; Reference Values; Skin; Tretinoin	2002
THE UPTAKE OF AMINO ACIDS BY MOUSE PANCREAS IN VITRO. I. GENERAL CHARACTERISTICS. Biochimica et biophysica acta, 1964, Jul-15, Volume: 90 Topics: Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cycloparaffins; Diabetes Mellitus, Experimental; Glycine; In Vitro Techniques; Mice; Ouabain; Pancreas; Pharmacology; Proline; Research; Sodium Chloride; Toxicology	1964
INFLUENCE OF CORTISOL AND INSULIN ON IN VITRO INCORPORATION OF AMINO ACIDS INTO PROTEIN OF GRANULOMA TISSUE. Endocrinology, 1964, Volume: 75 Topics: Adrenalectomy; Amino Acids; Animals; Carbon Isotopes; Diabetes Mellitus, Experimental; DNA; Glycine; Granuloma; Hydrocortisone; Hypophysectomy; In Vitro Techniques; Insulin; Pathology; Pharmacology; Proline; Proteins; Rats; Research; Tryptophan	1964
THE EFFECT OF DIABETES ON AMINO ACID ACCUMULATION AND PROTEIN SYNTHESIS IN ISOLATED RAT DIAPHRAGM. Biochimica et biophysica acta, 1965, May-04, Volume: 100 Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Diabetes Mellitus, Experimental; Diaphragm; Insulin Antibodies; Inulin; Muscles; Pancreatectomy; Proline; Protein Biosynthesis; Proteins; Rats; Research; Toxicology	1965
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy. Nephron. Physiology, 2003, Volume: 95, Issue:4 Topics: Albuminuria; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Atrophy; Blotting, Western; Cells, Cultured; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Fibroblasts; Fibronectins; Fibrosis; Humans; Immunohistochemistry; Kidney; Mice; ortho-Aminobenzoates; Proline; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Time Factors; Transforming Growth Factor beta; Tritium	2003
Slow orthograde axonal transport of radiolabelled protein in sciatic motoneurones of rats with short-term experimental diabetes: effects of treatment with an aldose reductase inhibitor or myo-inositol. Journal of neurochemistry, 1984, Volume: 43, Issue:5 Topics: Aldehyde Reductase; Animals; Axonal Transport; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Inositol; Male; Motor Neurons; Phthalazines; Proline; Rats; Rats, Inbred Strains; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases	1984
Glomerular basement membrane synthesis and serum concentration of type IV collagen in streptozotocin-diabetic rats. Diabetologia, 1984, Volume: 26, Issue:2 Topics: Age Factors; Animals; Basement Membrane; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Hydroxyproline; Kidney Glomerulus; Male; Proline; Radioimmunoassay; Rats; Rats, Inbred Strains; Time Factors	1984
In vivo biosynthesis and turnover of glomerular basement membrane in diabetic rats. The American journal of physiology, 1982, Volume: 242, Issue:4 Topics: Animals; Basement Membrane; Blood Glucose; Diabetes Mellitus, Experimental; Kidney Cortex; Kidney Glomerulus; Kinetics; Male; Proline; Proteins; Radioisotope Dilution Technique; Rats; Tritium	1982
In vivo studies on basement membrane synthesis in diabetic and nondiabetic rats. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1982, Volume: 181, Issue:3 Topics: Animals; Basement Membrane; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Glycine; Hydroxylysine; Hydroxyproline; Kidney Glomerulus; Male; Proline; Rats; Rats, Inbred Strains	1982
Deposition of basement membrane in vitro by normal and diabetic rat renal glomeruli. Nephron, 1981, Volume: 27, Issue:3 Topics: Animals; Basement Membrane; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydroxyproline; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Male; Membrane Proteins; Proline; Rats	1981
Collagen metabolism in the myocardium from streptozotocin-diabetic rats. Diabetes, 1980, Volume: 29, Issue:7 Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Glycosuria; Hydroxyproline; Male; Myocardium; Proline; Rats	1980
Renal endosomal phosphate (Pi) transport in normal and diabetic rats and response to chronic Pi deprivation. Cell biochemistry and function, 1997, Volume: 15, Issue:1 Topics: Animals; Biological Transport; Blotting, Western; Diabetes Mellitus, Experimental; Endosomes; Hypoglycemic Agents; Insulin; Male; Microvilli; Phosphates; Phosphorus; Phosphorus, Dietary; Proline; Rats; Rats, Sprague-Dawley; Sodium; Urine	1997
Stimulation of TGF-beta type II receptor by high glucose in mouse mesangial cells and in diabetic kidney. American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:5 Topics: Animals; Cells, Cultured; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Gene Expression; Glomerular Mesangium; Glucose; Mice; Mice, Inbred C57BL; Proline; Promoter Regions, Genetic; Receptors, Transforming Growth Factor beta; RNA Stability; RNA, Messenger; Transfection; Transforming Growth Factor beta	2000
Effects of estrogen to alter amino acid transport in R3230AC mammary carcinomas and its relationship to insulin action. Cancer research, 1979, Volume: 39, Issue:9 Topics: Adenocarcinoma; Amino Acids; Animals; Biological Transport; Castration; Cell Line; Diabetes Mellitus, Experimental; Estradiol; Estrogens; Female; In Vitro Techniques; Insulin; Insulin Antagonists; Leucine; Mammary Neoplasms, Experimental; Proline; Rats; RNA, Neoplasm; Streptozocin; Substrate Specificity; Time Factors	1979
Response of rat connective tissues to streptozotocin-diabetes. Tissue-specific effects on collagen metabolism. Biochimica et biophysica acta, 1979, Feb-19, Volume: 583, Issue:1 Topics: Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Hydroxyproline; Intestinal Mucosa; Male; Organ Size; Proline; Rats; Skin	1979
Glomerular basement membrane metabolism in the diabetic rat. In vivo studies. Diabetes, 1979, Volume: 28, Issue:2 Topics: Animals; Basement Membrane; Diabetes Mellitus, Experimental; Hydroxyproline; Kidney Glomerulus; Male; Proline; Rats	1979
Biosynthesis of skin collagens in normal and diabetic mice. The Biochemical journal, 1979, Aug-15, Volume: 182, Issue:2 Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Male; Mice; Organ Culture Techniques; Proline; Skin	1979
Effects of insulin in vivo and in vitro on amino acid transport into cells from the R3230AC mammary adenocarcinoma and their relationship to tumor growth. Cancer research, 1978, Volume: 38, Issue:11 Pt 1 Topics: Adenocarcinoma; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Insulin; Kinetics; Leucine; Mammary Neoplasms, Experimental; Proline; Rats; Sodium	1978
Wound healing: a model for the study of diabetic angiopathy. Diabetes, 1976, Volume: 25, Issue:2 SUPPL Topics: Animals; Capillaries; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; DNA; DNA Replication; Ear; Fibroblasts; Mice; Microscopy, Electron; Proline; Thymidine; Wound Healing	1976
Nifedipine versus fosinopril in uninephrectomized diabetic rats. Kidney international, 1992, Volume: 41, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Fosinopril; Hemodynamics; Longitudinal Studies; Nephrectomy; Nifedipine; Proline; Rats; Rats, Inbred Strains; Renal Circulation	1992
Tetracycline administration increases protein (presumably procollagen) synthesis and secretion in periodontal ligament fibroblasts of streptozotocin-induced diabetic rats. Journal of periodontal research, 1992, Volume: 27, Issue:6 Topics: Animals; Autoradiography; Diabetes Mellitus, Experimental; Fibroblasts; Male; Microscopy, Electron; Minocycline; Periodontal Ligament; Procollagen; Proline; Rats; Rats, Sprague-Dawley; Streptozocin; Tetracycline	1992
Tetracycline administration increases collagen synthesis in osteoblasts of streptozotocin-induced diabetic rats: a quantitative autoradiographic study. Calcified tissue international, 1992, Volume: 50, Issue:5 Topics: Animals; Autoradiography; Collagen; Diabetes Mellitus, Experimental; Male; Microscopy, Electron; Osteoblasts; Osteoporosis; Procollagen; Proline; Rats; Rats, Inbred Strains; Streptozocin; Tetracycline; Tritium	1992
Tetracycline administration restores osteoblast structure and function during experimental diabetes. The Anatomical record, 1991, Volume: 231, Issue:1 Topics: Alkaline Phosphatase; Animals; Calcium-Transporting ATPases; Diabetes Mellitus, Experimental; Disease Models, Animal; Humerus; Male; Minocycline; Osteoblasts; Osteoporosis; Proline; Rats; Rats, Inbred Strains; Tetracyclines	1991
Insulin-deficient diabetes impairs osteoblast and periodontal ligament fibroblast metabolism but does not affect ameloblasts and odontoblasts: response to tetracycline(s) administration. Journal de biologie buccale, 1990, Volume: 18, Issue:3 Topics: Ameloblasts; Animals; Autoradiography; Bone Matrix; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fibroblasts; Male; Odontoblasts; Osteoblasts; Periodontal Ligament; Periosteum; Proline; Rats; Rats, Inbred Strains; Streptozocin; Tetracycline; Tritium	1990
Metabolism of glomerular basement membrane in short- and long-term streptozotocin diabetic rats. Archives internationales de physiologie et de biochimie, 1986, Volume: 94, Issue:3 Topics: Animals; Basement Membrane; Collagen; Diabetes Mellitus, Experimental; Hydroxyproline; Kidney Glomerulus; Male; Proline; Proteins; Rats; Time Factors	1986
Correction of altered collagen metabolism in diabetic animals with insulin therapy. Matrix (Stuttgart, Germany), 1989, Volume: 9, Issue:4 Topics: Animals; Bone and Bones; Cartilage, Articular; Collagen; Diabetes Mellitus, Experimental; Insulin; Kinetics; Male; Proline; Rats; Rats, Inbred Strains	1989
Nutritional and hormonal regulation of articular collagen production in diabetic animals. Diabetes, 1989, Volume: 38, Issue:6 Topics: Animals; Cartilage, Articular; Collagen; Diabetes Mellitus, Experimental; Diet, Diabetic; Kinetics; Male; Nutritional Physiological Phenomena; Proline; Rats; Rats, Inbred Strains; Reference Values	1989
Metabolism of glomerular basement membrane in normal, hypophysectomized, and growth-hormone-treated diabetic rats. Experimental and molecular pathology, 1985, Volume: 43, Issue:2 Topics: Acetylglucosaminidase; Animals; Basement Membrane; Collagen; Diabetes Mellitus, Experimental; Glucosyltransferases; Growth Hormone; Hydroxyproline; Hypophysectomy; Kidney Glomerulus; Male; Proline; Rats	1985
Collagen metabolism in the retina of normal and diabetic rats. Experimental eye research, 1985, Volume: 41, Issue:3 Topics: Animals; Basement Membrane; Body Weight; Collagen; Diabetes Mellitus, Experimental; Glucosyltransferases; Hydroxyproline; Male; Microscopy, Electron; Proline; Rats; Rats, Inbred Strains; Retina; Retinal Vessels; Time Factors	1985
The in vivo fractional rate of gingival collagen production in non-diabetic and diabetic rats. Application of a novel approach for quantification-pool expansion. Journal of periodontal research, 1986, Volume: 21, Issue:1 Topics: Animals; Body Weight; Collagen; Diabetes Mellitus, Experimental; Gingiva; Hydroxyproline; Male; Proline; Rats; Rats, Inbred Strains; Tritium	1986
Abnormalities of granulation tissue and collagen formation in experimental diabetes, uraemia and malnutrition. Diabetic medicine : a journal of the British Diabetic Association, 1986, Volume: 3, Issue:3 Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Experimental; Granulation Tissue; Hydroxylation; Hydroxyproline; Imidazoles; Imidazolidines; Male; Nutrition Disorders; Proline; Rats; Rats, Inbred Strains; Uremia; Wound Healing	1986
Experimental diabetes and the lung. II. In vivo connective tissue metabolism. The American review of respiratory disease, 1988, Volume: 138, Issue:2 Topics: Animals; Collagen; Connective Tissue; Diabetes Mellitus, Experimental; DNA; Elastin; Hydroxyproline; Insulin; Lung; Male; Nutrition Disorders; Proline; Protein Biosynthesis; Rats; Rats, Inbred Strains; Thymidine	1988
Streptozotocin-induced diabetes and the rat periodontium: decreased relative collagen production. Collagen and related research, 1988, Volume: 8, Issue:3 Topics: Animals; Collagen; Diabetes Mellitus, Experimental; Male; Periodontium; Proline; Rats; Rats, Inbred Strains; Skin	1988
Nutrient uptake by rat enterocytes during diabetes mellitus; evidence for an increased sodium electrochemical gradient. The Journal of physiology, 1988, Volume: 397 Topics: Animals; Diabetes Mellitus, Experimental; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Membrane Potentials; Microvilli; Proline; Rats; Rats, Inbred Strains; Sodium	1988
Diabetes stimulates procollagen degradation in rat tendon in vitro. Biochimica et biophysica acta, 1986, Feb-19, Volume: 880, Issue:2-3 Topics: Animals; Connective Tissue; Densitometry; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Male; Photofluorography; Procollagen; Proline; Rats; Rats, Inbred Strains; Tendons	1986
Dietary ascorbic acid normalizes diabetes-induced underhydroxylation of nascent type I collagen molecules. Collagen and related research, 1985, Volume: 5, Issue:5 Topics: Animals; Ascorbic Acid; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Diet; Hydroxylation; Macromolecular Substances; Male; Proline; Rats; Rats, Inbred Strains; Skin; Tritium	1985
C14-proline metabolism in alloxan treated rats. Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1970, Volume: 34, Issue:3 Topics: Animals; Carbon Isotopes; Diabetes Mellitus, Experimental; Hydroxyproline; Peptides; Proline; Rats	1970
Intestinal adaptation in diabetes: amino acid absorption. The American journal of physiology, 1974, Volume: 227, Issue:4 Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Chromatography, Paper; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glycine; Intestinal Absorption; Intestinal Mucosa; Leucine; Lysine; Male; Organ Size; Proline; Rats; Serous Membrane; Streptozocin; Time Factors	1974
Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase. The Journal of biological chemistry, 1971, Apr-25, Volume: 246, Issue:8 Topics: Adrenal Glands; Adrenalectomy; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chromatography, DEAE-Cellulose; Cortisone; Crystallization; Diabetes Mellitus, Experimental; Electrophoresis, Disc; Enzyme Induction; Glucagon; Hydro-Lyases; Immune Sera; Immunodiffusion; Isoenzymes; L-Serine Dehydratase; Leucine; Liver; Lysine; Male; Molecular Weight; Phosphates; Proline; Pyridoxal Phosphate; Rats; Spectrophotometry; Tritium; Ultraviolet Rays	1971
The effect of alloxan diabetes on skin collagen metabolism. Experientia, 1972, May-15, Volume: 28, Issue:5 Topics: Animals; Carbon Isotopes; Collagen; Diabetes Mellitus, Experimental; Lysine; Male; Proline; Rats; Rats, Inbred Strains; Skin; Wound Healing	1972
Correlation between the antilipolytic and hypoglycemic actions of some salicylate structural congeners in normal and alloxan-diabetic rats. Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 178, Issue:2 Topics: Animals; Anti-Bacterial Agents; Benzoates; Blood Glucose; Coumarins; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Furans; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Nicotinic Acids; ortho-Aminobenzoates; Proline; Rats; Salicylates; Thiophenes	1969