proline and Aging

proline has been researched along with Aging in 172 studies

Research

Studies (172)

TimeframeStudies, this research(%)All Research%
pre-1990102 (59.30)18.7374
1990's42 (24.42)18.2507
2000's20 (11.63)29.6817
2010's7 (4.07)24.3611
2020's1 (0.58)2.80

Authors

AuthorsStudies
Chen, Y; Deng, S; Luo, H; Tian, Y; Wang, Q; Wang, S1
Julku, UH; Kilpeläinen, T; Myöhänen, TT; Svarcbahs, R1
Gonzalez-Añover, P; Gonzalez-Bulnes, A1
Li, B; Song, H; Zhang, L; Zhang, S1
Jamie, J; Kwan, AH; Lyons, B; Truscott, RJ1
Cummins, I; Johnson, SM; Knight, MR; Lim, FL; Slabas, AR1
Iida, M; Kato, M; Kumasaka, MY; Li, X; Ohgami, N; Oshino, R; Yajima, I1
Lowel, S; Schmidt, KE; Singer, W1
Gureviciene, I; Gurevicius, K; Tanila, H1
Druga, R; Folbergrová, J; Haugvicová, R; Otáhal, J; Tsenov, G1
Bonfigli, AR; Fazioli, F; Franceschi, C; Invidia, L; Lanari, L; Marcheselli, F; Marra, M; Olivieri, F; Pierini, M; Recchioni, R; Salvioli, S; Sirolla, C; Testa, I; Testa, R1
Chi, H; Kitaoka, N; Kodama, H; Liu, G; Lu, J; Nakayama, K; Tong, J; Yamashita, K1
Delwing, D; Ferreira, AG; Kolling, J; Lima, DD; Mackedanz, V; Schuck, PF; Tagliari, B; Wajner, M; Wyse, AT1
Cappellin, E; De Palo, EF; Gatti, R; Lancerin, F; Sartorio, A; Spinella, P1
Bader, DL; Berry, CC; Cacou, C; Lee, DA; Shelton, JC1
Berenson, GS; Boerwinkle, E; Chen, W; Li, S; Srinivasan, SR1
CHVAPIL, M2
MURRAY, DH; RING, JR; WATTS, WR1
BERTELSEN, S1
CLAUSEN, B1
BIELECKI, B1
CHVAPIL, M; KOBRLE, V2
Bernhart, T; Frickey, N; Knolle, E; Oehmke, HJ; Oehmke, MJ; Schramm, CR1
Bialek, P; Hong, N; Justice, MJ; Karsenty, G; Kern, B; Olson, EN; Ornitz, DM; Schrock, M; Sosic, D; Wu, H; Yang, X; Yu, K1
Gonzalez, FJ; Inoue, Y; Kamiya, A; Kodama, T1
Buschmann, MD; Henderson, JE; Hoemann, CD; McKee, MD; Tran-Khanh, N1
Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C1
El-Assar, M; Nevado, J; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF; Vallejo, S1
Beamer, B; Cummings, SR; Harris, T; Hsueh, WC; Kanaya, AM; Li, R; Lindquist, K; Newman, A; Rosano, C; Yaffe, K1
D'Souza, M; Frisina, RD; Tadros, SF; Waxmonsky, NC; Zettel, ML; Zhu, X1
Nakagawa, T; Sugiura, Y1
Bavetta, LA; Deshmukh, K; Nimni, ME1
Aurell, M; Jodal, U; Sigström, L1
Silberbauer, K; Stanek, B1
Adinolfi, AM; Cospito, JA; Levine, MS1
Dixon, PG; Pearson, LJ; Sanderson, KJ1
Bouissou, H; Julian, M; Maurel, E; Pieraggi, MT1
Ayres, NA; Gomez, RA; Lawton, WJ; Robillard, JE; VanOrden, DE; Weismann, DN1
Asiedu, S; Stahl, SS; Tonna, EA1
Herskovits, MS; Singh, IJ1
Blow, AJ; Ershler, WB; Gamelli, RL; Hacker, MP; Moore, AL1
Imai, K; Kato, T; Kumegawa, M; Maeda, N; Nagatsu, T; Yajima, T1
Baum, BJ; Kousvelari, EE; Oppenheim, FG1
Bailey, AJ; Etherington, DJ1
Davison, PF; Lee, RE1
Specht, SC1
Ahrens, FA; Rodolfo-Sioson, SA1
Knabe, DA; Wu, G1
Campa, JS; Laurent, GJ; Mays, PK; McAnulty, RJ2
Nakamura, T; Pichel, JG; Westphal, H; Williams-Simons, L1
Münzel-Pedrazzoli, S; Schroeder, HE1
Higuchi, K; Naiki, H; Nakakuki, K; Shimada, A; Takeda, T1
Lipkowitz, MS; Medow, MS1
Arola, LI; Salvadó, MJ1
Livne, E; Weiss, A1
Arai, T; Hasegawa, M; Ihara, Y; Kosik, KS; Morishima-Kawashima, M; Suzuki, M; Takio, K; Titani, K; Watanabe, A1
Chen, AC; Grodzinsky, AJ; Sah, RL; Trippel, SB1
Atkinson, JC; Baum, BJ; Fox, PC; Ship, JA; Wu, AJ1
Kocsis, JD; Lim, JY; Sakatani, K; Utzschneider, DA1
Ferraris, RP; Vinnakota, RR1
Hawkins, RL; Inoue, M; Mori, M; Torii, K1
Burrill, MJ; D'Avis, P; Fedarko, NS; Fergusson, V; Frazier, CR; Shapiro, JR; Sponseller, PD; Tayback, M1
Bosch, A; Estivill, X; Ferrer, I; Fuentes, JJ; Planas, AM; Pritchard, MA1
Jacob, JM1
Nagy, IZ1
Baldwin, RL; Jesse, BW; Wang, L1
Gonzalez, E; Vinardell, MP1
Ayala, A; Cutler, RG1
Flynn, NE; Flynn, SP; Knabe, DA; Wu, G; Yan, W1
Belagaje, R; Burnett, JP; Johnson, BG; Mayne, NG; Monn, JA; Salhoff, CR; Schoepp, DD; Wright, RA; Wu, S1
Rosenthal, AK; Ryan, LM1
Flynn, NE; Wu, G1
Wu, G1
Baker, GE; Ruthazer, ES; Stryker, MP1
Ashworth, JL; Kielty, CM; Murphy, G; Rock, MJ; Shapiro, SD; Sherratt, MJ; Shuttleworth, CA1
Beaver, CJ; Daw, NW; Ji, Q1
Keshava, C; McCanlies, EC; Sharp, DS; Sun, Y; Weston, A1
Koike, K; Li, Y; Sakurada, I; Seo, M; Tezuka, K; Uchikawa, K; Uchikura, K1
Buddington, RK; Elnif, J; Malo, C; Sangild, PT1
Cao, QX; Ferraris, RP; Prabhakaram, S1
Beilby, JP; Chapman, CM; Hung, J; McQuillan, BM; Swarbrick, MM; Thompson, PL1
Ali, M; Ruiz-Torres, A1
McClure, WO; McLane, JA1
Miller, SA; Nakamoto, T1
Stahl, SS; Tonna, EA1
Wohlrab, H1
Carsten, AL; Skougaard, MR1
Kameyama, Y; Uyeno, K1
Hirschmann, PN; Shuttleworth, CA; Ward, JL1
Blumen, G1
Hama, T; Kato, T; Kuzuya, H; Nagatsu, T; Sakakibara, S1
Kumar, N1
Hoyer, JR; Spiro, RG1
Miyahara, T; Murai, A; Shiozawa, S1
Romen, W1
Ito, K; Nakano, H; Nomoto, S; Ohnishi, S1
Kunz, J1
Lee, I; Rucker, RB; Yau, C1
Granger, AS; Kowaloff, EM; Phang, JM1
Bondy, SC; Purdy, JL1
Tonna, EA4
Forrest, L; Shuttleworth, CA1
Roy, D; Spector, A; Stauffer, J1
Reynolds, RA; Segal, S1
Löwel, S; Singer, W1
Buddington, RK; Puchal, AA; Vega, YM1
Hergueta, S; Lemire, M; Repérant, J; Rio, JP; Ward, R1
Atherton, J; Cortes, P; Dumler, F; Tilley, BC; Zhao, X1
Jeanson, SE; Kellogg, TF1
Amat, C; Buddington, RK; Moretó, M; Planas, JM; Puchal, A1
Laurent, GJ; Mays, PK; McAnulty, RJ1
Bar-Shira-Maymon, B; Coleman, R; Reznick, A; Silbermann, M; Steinhagen-Thiessen, E; von der Mark, H; von der Mark, K; Weisman, Y1
Czudek, C; Reynolds, GP1
Diamond, JM; Toloza, EM2
Hendriks, T; Martens, MF1
Cariola, CM; Fenstermacher, EA; Hsu, BY; McNamara, PD; Rea, CT; Reynolds, RA; Segal, S1
Acton, KS; Ball, RO; Samuels, SE1
Price, DJ; Zumbroich, TJ1
Kato, H; Naito, H; Nam, TJ; Noguchi, T1
Avioli, LV; Bigazzi, S; Civitelli, R; Gennari, C; Gonnelli, S; Vattimo, A; Zacchei, F1
Albini, A; Allavena, G; Mensing, H; Müller, PK; Pontz, B; Pulz, M1
Fómez-Pinilla, F; Hovda, DA; Sonnier, BJ; Villablanca, JR1
Bikle, DD; Cone, CM; Globus, RK; Halloran, BP; Morey-Holton, E1
Kador, PF; Kinoshita, JH; Shiono, T1
Dubick, MA; Gerriets, JE; Last, JA; Myers, BA; Reiser, KM; Rucker, RB1
Giacobini, E; Gutierrez, MD1
Gibson, J; Laurent, GJ; McAnulty, RJ1
Robert, AM; Robert, B; Robert, L1
O'Brien, SJ; Shimada, Y1
Ferguson, JL; Fink, CW; Smiley, JD1
Carney, SA; Lawrence, JC; McConkey, B; Ricketts, CR; Walton, KW1
Ebel, A1
Kadar, A; Robert, B; Robert, L1
De Hesse, C; Houck, JC; Jacob, R1
Angrist, AA; Brodie, SS; Oka, M1
Gregson, N; Hamberger, A; Lehninger, AL1
Hruza, Z; Jolma, VH1
Angrist, A; Nakao, K; Oka, M1
Asboe-Hansen, G; Blumenkrantz, N1
Boross, M; Pénzes, L1
Platt, D; Rühl, W1
Bulos, B; Sacktor, B; Shukla, S1
De Loecker, W; Stas, ML1
Lapiere, CM; Nusgens, B2
De Luca, F; Macaione, S; Ruggeri, P; Tucci, G1
Seyer, JM; Vinson, WC1
Bartter, FC; Henneman, DH; Lifschitz, MD; Pak, CY; Sanzenbacher, L1
Aalto, M; Heikkinen, E; Kulonen, E; Vihersaari, T1
Walker, DG1
Baerlocher, KE; Mohyuddin, F; Scriver, CR1
Pavelec, M; Tonna, EA1
Nemetschek, T1
Halme, J; Hannuksela, M; Kivirikko, KI; Peltokallio, P; Uitto, J1
Jackson, DS1
Uitto, J1
Ohuchi, K; Tsurufuji, S1
De Angelis, V1
Brown, DD; Goldberg, B; Green, H; Schwartz, M1
Flanagan, B; Nichols, G1
Batt, ER; Schachter, D1
Fukushi, S; Spiro, RG1
Hanzlik, J1
Fritz, RR; Rappoport, DA; Yamagami, S1

Reviews

6 review(s) available for proline and Aging

ArticleYear
On the possible role of nootropica in geriatric prevention and therapy.
    Annals of the New York Academy of Sciences, 1996, Jun-15, Volume: 786

    Topics: Aging; Free Radical Scavengers; Humans; Nootropic Agents; Piracetam; Proline; Selegiline

1996
[On the pathogenesis of the glomerulosclerosis ultrastructural and autoradiographic investigations on the rat kidney (author's transl)].
    Veroffentlichungen aus der Pathologie, 1976, Issue:102

    Topics: Aging; Animals; Autoradiography; Basement Membrane; Collagen; Hemostasis; Hypertension; Hypoxia; Kidney Glomerulus; Ligation; Male; Morpholines; Nephrectomy; Nitroso Compounds; Proline; Rats; Renal Veins

1976
Molecular biology of elastin as related to aging and atherosclerosis.
    Experimental gerontology, 1970, Volume: 5, Issue:4

    Topics: Aging; Animals; Antibody Formation; Arteriosclerosis; Calorimetry; Carbon Isotopes; Cattle; Elastin; Fluorescent Antibody Technique; gamma-Globulins; Glycoproteins; Hexosamines; Hexoses; Humans; Immunochemistry; Krypton; Molecular Biology; Neuraminic Acids; Proline; Protein Denaturation; Rabbits; Solvents; Surface Properties; Swine

1970
[The amount and biochemistry of vascular collagen].
    Angiologica, 1969, Volume: 6, Issue:2

    Topics: Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Vessels; Brachiocephalic Trunk; Carotid Arteries; Collagen; Connective Tissue; Connective Tissue Cells; Dogs; Elasticity; Glycosaminoglycans; Histocytochemistry; Humans; Iliac Artery; Models, Chemical; Proline; Pulmonary Artery; Rabbits; Thoracic Arteries

1969
The macromolecules of the intercellular matrix of the arterial wall: collagen, elastin, proteoglycans, and glycoproteins.
    Advances in experimental medicine and biology, 1974, Volume: 43, Issue:0

    Topics: Age Factors; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Carbon Radioisotopes; Chickens; Collagen; Connective Tissue; Connective Tissue Cells; Elastin; Endothelium; Female; Glycoproteins; Glycosaminoglycans; Humans; Hydroxyproline; Hypertension; In Vitro Techniques; Lysine; Male; Microscopy, Electron; Muscle, Smooth; Proline; Rabbits; Rats; Swine

1974
[Cellular kinetics of bone and aging (report) (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1974, Volume: 58

    Topics: Aging; Animals; Bone and Bones; Bone Development; Cell Movement; Femoral Fractures; Femur; Mice; Periosteum; Proline; Tritium

1974

Trials

1 trial(s) available for proline and Aging

ArticleYear
Maternal age modulates the effects of early-pregnancy L-proline supplementation on the birth-weight of piglets.
    Animal reproduction science, 2017, Volume: 181

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Birth Weight; Diet; Dietary Supplements; Female; Humans; Litter Size; Pregnancy; Pregnancy, Animal; Prenatal Nutritional Physiological Phenomena; Proline; Swine

2017

Other Studies

165 other study(ies) available for proline and Aging

ArticleYear
Mechanisms of the ethanol extract of
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Adenine; Aging; Amino Acids; Animals; Antioxidants; Catalase; Cholic Acid; Drosophila; Ethanol; Free Radicals; Glutamates; Lipids; Male; Malondialdehyde; Methanol; Niacin; Plant Extracts; Proline; Rhodophyta; Sugars; Superoxide Dismutase

2022
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
    Scientific reports, 2019, 11-22, Volume: 9, Issue:1

    Topics: Aging; Alanine; alpha-Synuclein; Amino Acid Substitution; Animals; Behavior, Animal; Disease Models, Animal; Dopaminergic Neurons; Humans; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Parkinson Disease; Proline; Threonine

2019
Effect of Orally Administered Collagen Peptides from Bovine Bone on Skin Aging in Chronologically Aged Mice.
    Nutrients, 2017, Nov-03, Volume: 9, Issue:11

    Topics: Administration, Oral; Age Factors; Aging; Animals; Antioxidants; Cattle; Collagen; Collagenases; Elasticity; Female; Mice; Peptide Fragments; Proline; Skin; Skin Aging; Subtilisins; Time Factors

2017
Age-dependent modification of proteins: N-terminal racemization.
    The FEBS journal, 2013, Volume: 280, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; alpha-Crystallin B Chain; Amino Acid Sequence; Aquaporins; Eye Proteins; Humans; Isomerism; Lens, Crystalline; Methionine; Peptide Fragments; Proline; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Tandem Mass Spectrometry

2013
Transcriptomic analysis comparing stay-green and senescent Sorghum bicolor lines identifies a role for proline biosynthesis in the stay-green trait.
    Journal of experimental botany, 2015, Volume: 66, Issue:22

    Topics: Aging; Base Sequence; DNA, Plant; Droughts; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Microarray Analysis; Molecular Sequence Data; Phenotype; Polymorphism, Single Nucleotide; Proline; Sorghum

2015
Manganese-mediated acceleration of age-related hearing loss in mice.
    Scientific reports, 2016, 11-08, Volume: 6

    Topics: Aging; Animals; Disease Models, Animal; Hearing Loss; Hydroxylation; Hypoxia-Inducible Factor 1, alpha Subunit; Manganese; Mice; Mice, Transgenic; Nerve Degeneration; Phosphorylation; Proline; Proto-Oncogene Proteins c-ret; Spiral Ganglion; Up-Regulation

2016
Binocular phasic coactivation does not prevent ocular dominance segregation.
    Frontiers in bioscience : a journal and virtual library, 2008, May-01, Volume: 13

    Topics: Aging; Animals; Autoradiography; Carbon Radioisotopes; Cats; Deoxyglucose; Dominance, Ocular; Neurons; Proline; Retina; Tritium; Vision, Binocular; Vision, Ocular

2008
Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:1

    Topics: Aging; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Dentate Gyrus; Electric Stimulation; Escape Reaction; Excitatory Postsynaptic Potentials; Humans; Locomotion; Mice; Mice, Transgenic; Mutation; Neuronal Plasticity; Perforant Pathway; Proline; Reaction Time; Synapses; Time Factors

2009
Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats.
    Brain research, 2009, Jun-01, Volume: 1273

    Topics: Aging; Animals; Brain; Convulsants; Cytoprotection; Drug Administration Schedule; Drug Interactions; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; Homocysteine; Male; Nerve Degeneration; Neuroprotective Agents; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus; Treatment Outcome

2009
The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing.
    Mechanisms of ageing and development, 2009, Volume: 130, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Codon; Female; Genes, p53; Genotype; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Proline; Tumor Suppressor Protein p53

2009
Activity of prolidase isoenzymes in the rat brain: subcellular and regional distribution during development.
    Brain research, 2009, Dec-15, Volume: 1303

    Topics: Aging; Animals; Brain; Brain Chemistry; Chromatography, DEAE-Cellulose; Dipeptidases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Male; Prolidase Deficiency; Proline; Rabbits; Rats; Rats, Wistar

2009
Proline impairs energy metabolism in cerebral cortex of young rats.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Brain Diseases, Metabolic; Cerebral Cortex; Disease Models, Animal; Drug Synergism; Energy Metabolism; Lipid Peroxidation; Oxidative Stress; Proline; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

2010
The measurement of insulin-like growth factor-I (IGF-I) concentration in random urine samples.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Aging; Body Height; Body Weight; C-Peptide; Child; Creatinine; Electrophoresis, Polyacrylamide Gel; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Proline; Radioimmunoassay; Random Allocation; Reference Values; Regression Analysis; Sampling Studies; Spectrophotometry

2002
Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner.
    Biorheology, 2003, Volume: 40, Issue:1-3

    Topics: Adult; Aging; Cell Culture Techniques; Cell Division; Cell Line; Cell Size; Cell Survival; Collagen; Fibroblasts; Humans; Infant, Newborn; Mechanotransduction, Cellular; Physical Stimulation; Proline; Skin; Stress, Mechanical; Thymidine

2003
The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study.
    Diabetes, 2003, Volume: 52, Issue:5

    Topics: Adult; Aging; Alanine; Amino Acid Substitution; Blood Glucose; Child; Genotype; Homeostasis; Humans; Insulin; Insulin Resistance; Mutation, Missense; Polymorphism, Single Nucleotide; Proline; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2003
[Studies on fibroplasia. III. Hydroxyproline in scleroproteins in the lungs in ontogenesis in rats].
    Ceskoslovenska fysiologie, 1956, Volume: 5, Issue:4

    Topics: Aging; Animals; Fibrosis; Hydroxyproline; Lung; Proline; Proteins; Rats; Scleroproteins

1956
A study of fibroplasia. III. Hydroxyproline content of scleroproteins in the lungs of rats during ontogeny.
    Physiologia bohemoslovenica, 1956, Volume: 5, Issue:4

    Topics: Aging; Animals; Fibrosis; Hydroxyproline; Lung; Proline; Proteins; Rats; Scleroproteins

1956
Hexosamine and hydroxyproline concentrations in skin and buccal mucosa of an aging rat population.
    Journal of gerontology, 1961, Volume: 16

    Topics: Aging; Amino Sugars; Animals; Hexosamines; Hydroxyproline; Mouth Mucosa; Proline; Rats; Skin

1961
Hexosamine, hydroxyproline, and calcium levels in the intima of the human aorta as related to age and atherosclerotic changes.
    Journal of gerontology, 1962, Volume: 17

    Topics: Aging; Amino Sugars; Aorta; Arteriosclerosis; Calcium; Hexosamines; Hydroxyproline; Proline; Tunica Intima

1962
Influence of age on connective tissue. Hexosamine and hydroxyproline in human aorta, myocardium, and skin.
    Laboratory investigation; a journal of technical methods and pathology, 1962, Volume: 11

    Topics: Aging; Amino Sugars; Aorta; Connective Tissue; Hexosamines; Hydroxyproline; Myocardium; Proline; Skin

1962
[BEHAVIOR OF THE COMPONENTS OF THE CONNECTIVE TISSUE OF THE WALL OF THE AORTA AND CORONARY ARTERIES IN VARIOUS AGES].
    Polskie Archiwum Medycyny Wewnetrznej, 1963, Volume: 33

    Topics: Adolescent; Aging; Aorta; Calcium; Child; Collagen; Connective Tissue; Coronary Vessels; Geriatrics; Glycine; Hexosamines; Histocytochemistry; Humans; Hydroxyproline; Infant; Proline

1963
Changes of ultrafiltrable hydroxyproline in blood serum during development of carrageenin granuloma and during aging of rats and guinea-pigs.
    Experientia, 1961, Nov-15, Volume: 17

    Topics: Aging; Animals; Carrageenan; Granuloma; Guinea Pigs; Hydroxyproline; Plants; Proline; Rats; Serum

1961
The amount of ultrafiltrable and collagen-bound hydroxyproline in different organs of the rat during aging.
    Physiologia bohemoslovenica, 1962, Volume: 11

    Topics: Aging; Animals; Biophysical Phenomena; Collagen; Hydroxyproline; Proline; Rats; Ultrafiltration

1962
Age-dependent changes of the periodontal ligament in rats.
    Microscopy research and technique, 2004, Mar-01, Volume: 63, Issue:4

    Topics: Aging; Animals; Autoradiography; Collagen; Image Processing, Computer-Assisted; Male; Molar; Periodontal Ligament; Proline; Rats; Rats, Wistar

2004
A twist code determines the onset of osteoblast differentiation.
    Developmental cell, 2004, Volume: 6, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Cell Differentiation; Cells, Cultured; Chlorocebus aethiops; Core Binding Factor Alpha 1 Subunit; DNA Mutational Analysis; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Gene Expression Regulation; Heterozygote; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myogenic Regulatory Factors; Neoplasm Proteins; Nuclear Proteins; Osteoblasts; Osteogenesis; Precipitin Tests; Proline; Protein Structure, Tertiary; Rats; Repressor Proteins; RNA; Serine; Skeleton; Staining and Labeling; Transcription Factors; Transcriptional Activation; Transfection; Twist-Related Protein 1

2004
Hepatocyte nuclear factors 1alpha and 4alpha control expression of proline oxidase in adult liver.
    FEBS letters, 2004, Dec-03, Volume: 578, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Base Sequence; Binding Sites; Consensus Sequence; DNA-Binding Proteins; Embryo, Mammalian; Gene Expression Regulation, Enzymologic; Genes, Reporter; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 4; Liver; Mice; Mice, Knockout; Molecular Sequence Data; Nuclear Proteins; Phosphoproteins; Proline; Proline Oxidase; Promoter Regions, Genetic; Transcription Factors

2004
Aged bovine chondrocytes display a diminished capacity to produce a collagen-rich, mechanically functional cartilage extracellular matrix.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:6

    Topics: Aging; Animals; Biomechanical Phenomena; Cartilage, Articular; Cattle; Cell Count; Chondrocytes; Collagen; Extracellular Matrix Proteins; Glycosaminoglycans; Proline; Sulfates

2005
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
    Cell cycle (Georgetown, Tex.), 2005, Volume: 4, Issue:9

    Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection

2005
Changes in the human peritoneal mesothelial cells during aging.
    Kidney international, 2006, Volume: 69, Issue:2

    Topics: Adult; Aged; Aging; Cytokines; Epithelial Cells; Female; Humans; Indomethacin; Inflammation; Male; Middle Aged; NF-kappa B; Nitric Oxide Synthase; Peritoneal Cavity; Proline; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Thiocarbamates

2006
PPAR-gamma Pro12Ala genotype and risk of cognitive decline in elders.
    Neurobiology of aging, 2008, Volume: 29, Issue:1

    Topics: Aged; Aging; Alanine; Black People; Cognition Disorders; Female; Genotype; Humans; Longitudinal Studies; Male; Mental Status Schedule; Neuropsychological Tests; PPAR gamma; Proline; Retrospective Studies; Risk; White People

2008
Glutamate-related gene expression changes with age in the mouse auditory midbrain.
    Brain research, 2007, Jan-05, Volume: 1127, Issue:1

    Topics: Aging; Animals; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Female; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Inferior Colliculi; Male; Mice; Mice, Inbred CBA; Neurotoxins; Oligonucleotide Array Sequence Analysis; Ornithine-Oxo-Acid Transaminase; Presbycusis; Proline; Up-Regulation

2007
[Joint study on leg equalization. I. Basic study of the bone growth].
    Nihon Seikeigeka Gakkai zasshi, 1966, Volume: 40, Issue:5

    Topics: Aging; Animals; Bone Development; Chick Embryo; Collagen; Female; Guinea Pigs; Hexosamines; Humans; Male; Proline; Rabbits; Rats

1966
Turnover and age distribution of a collagen fraction extractable from rat skin by mercaptoethylamine.
    Archives of biochemistry and biophysics, 1967, Volume: 122, Issue:2

    Topics: Aging; Animals; Carbon Isotopes; Centrifugation, Zonal; Chemical Phenomena; Chemistry, Physical; Collagen; Cysteamine; Electrophoresis, Disc; Male; Mercaptoethylamines; Proline; Rats; Skin; Solubility

1967
Angiotensin converting enzyme inhibitor treatment of hypertension in infancy and childhood.
    Scandinavian journal of urology and nephrology. Supplementum, 1984, Volume: 79

    Topics: Adolescent; Aging; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Male; Proline; Renin

1984
[Age dependence of the response of blood pressure, heart rate and plasma renin activity to captopril in essential hypertension].
    Acta medica Austriaca, 1984, Volume: 11, Issue:3-4

    Topics: Adult; Aged; Aging; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Proline; Renin

1984
Organization of developing precruciate corticostriate projections in kittens.
    Experimental neurology, 1980, Volume: 67, Issue:2

    Topics: Aging; Animals; Axonal Transport; Brain; Cats; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Leucine; Proline; Putamen

1980
Postnatal development of retinal projections in the brushtailed possum, Trichosurus vulpecula.
    Brain research, 1982, Volume: 281, Issue:2

    Topics: Aging; Animals; Axonal Transport; Body Weight; Brain; Female; Geniculate Bodies; Opossums; Organ Size; Proline; Retina; Superior Colliculi

1982
Age dependent biochemical changes in dermal connective tissue. Relationship to histological and ultrastructural observations.
    Connective tissue research, 1980, Volume: 8, Issue:1

    Topics: Adult; Aged; Aging; Biopsy; Collagen; Glucosamine; Humans; Microbial Collagenase; Middle Aged; Pancreatic Elastase; Proline; Proteins; Skin

1980
Renal and adrenal responses to converting-enzyme inhibition in fetal and newborn life.
    The American journal of physiology, 1983, Volume: 244, Issue:2

    Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Captopril; Fetal Blood; Kidney; Proline; Sheep

1983
A study of the reformation of severed gingival fibers in aging mice using 3H-proline autoradiography.
    Journal of periodontal research, 1980, Volume: 15, Issue:1

    Topics: Aging; Animals; Autoradiography; Bone Matrix; Female; Gingiva; Male; Mice; Proline; Wound Healing

1980
Effect of guanethidine-induced sympathectomy on osteoblastic activity in the rat femur evaluated by 3H-proline autoradiography.
    Acta anatomica, 1984, Volume: 120, Issue:3

    Topics: Aging; Animals; Autoradiography; Female; Femur; Guanethidine; Male; Osteoblasts; Proline; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Tritium

1984
Experimental tumors and aging: local factors that may account for the observed age advantage in the B16 murine melanoma model.
    Experimental gerontology, 1984, Volume: 19, Issue:6

    Topics: Aging; Animals; Collagen; Male; Melanoma; Mice; Mice, Inbred C57BL; Proline; Wound Healing

1984
Developmental changes in the activities of prolinase and prolidase in rat salivary glands, and the effect of thyroxine administration.
    Molecular and cellular biochemistry, 1982, Jan-16, Volume: 42, Issue:1

    Topics: Aging; Animals; Brain; Dipeptidases; Kinetics; Male; Proline; Rats; Rats, Inbred Strains; Salivary Glands; Substrate Specificity; Thyroxine; Tissue Distribution

1982
Exocrine protein secretion from human parotid glands during aging: stable release of the acidic proline-rich proteins.
    Journal of gerontology, 1982, Volume: 37, Issue:4

    Topics: Adult; Aged; Aging; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Parotid Gland; Peptides; Proline; Proline-Rich Protein Domains; Salivary Proteins and Peptides

1982
Metabolism of rat skin collagen: the effect of arrested development and subsequent catch-up growth on the stability of the connective tissue fibers.
    Collagen and related research, 1982, Volume: 2, Issue:6

    Topics: Aging; Animals; Collagen; Connective Tissue; Growth Disorders; Male; Proline; Protein Deficiency; Rats; Rats, Inbred Strains; Skin

1982
Collagen composition and turnover in ocular tissues of the rabbit.
    Experimental eye research, 1981, Volume: 32, Issue:6

    Topics: Aging; Animals; Collagen; Cornea; Eye; Eyelids; Half-Life; Proline; Rabbits; Sclera

1981
Transneuronal transfer of radioactive substances during postnatal development of the hamster visual system.
    Experimental neurology, 1980, Volume: 69, Issue:2

    Topics: Aging; Animals; Cricetinae; Female; Fucose; Geniculate Bodies; Male; Neurons; Optic Nerve; Proline; Tritium; Visual Cortex; Visual Pathways

1980
The effects of lead on collagen biosynthesis in neonatal rats.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Collagen; Female; Hydroxyproline; Lead; Pregnancy; Proline; Rats; Skin

1980
Arginine synthesis in enterocytes of neonatal pigs.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Body Fluids; Citrulline; DNA; Glutamine; Jejunum; Kidney; Ornithine; Osmolar Concentration; Proline; Swine

1995
Age-related alterations in collagen and total protein metabolism determined in cultured rat dermal fibroblasts: age-related trends parallel those observed in rat skin in vivo.
    The international journal of biochemistry & cell biology, 1995, Volume: 27, Issue:9

    Topics: Aging; Animals; Cell Line; Collagen; Fibroblasts; Hydroxyproline; Proline; Rats; Skin

1995
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-20, Volume: 92, Issue:13

    Topics: Aging; Alanine; Alleles; Animals; Apoptosis; Arginine; Cell Differentiation; Codon; Epithelial Cells; Gene Expression; Genes, p53; Genetic Therapy; Humans; Lens, Crystalline; Mice; Mice, Transgenic; Microphthalmos; Point Mutation; Proline; Tumor Suppressor Protein p53; Valine

1995
[Attrition, dentin apposition and protein synthesis in the pulp and desmodont of young and old rats].
    Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 1994, Volume: 104, Issue:6

    Topics: Aging; Animals; Autoradiography; Dental Pulp Cavity; Dentinogenesis; Molar; Periodontal Ligament; Proline; Protein Biosynthesis; Rats; Tooth Abrasion; Tritium

1994
Genetic analysis of murine senile amyloidosis.
    Laboratory investigation; a journal of technical methods and pathology, 1993, Volume: 68, Issue:3

    Topics: Aging; Amyloidosis; Animals; Dementia; DNA; Genotype; Glutamine; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proline; Protein Precursors; Serum Amyloid A Protein; Spectrometry, Fluorescence

1993
Developmental changes of renal brushborder membrane ionic permeability.
    Biochimica et biophysica acta, 1994, Apr-20, Volume: 1191, Issue:1

    Topics: Aging; Animals; Anions; Biological Transport; Cations, Monovalent; Cell Membrane Permeability; Female; Fluorescence Polarization; Glucose; Kidney; Liposomes; Male; Membrane Fluidity; Microvilli; Potassium Chloride; Proline; Rats; Rats, Sprague-Dawley

1994
Glutamine force-feeding effect on plasma amino-acid concentrations in growing rats fed a cafeteria diet.
    Reproduction, nutrition, development, 1994, Volume: 34, Issue:2

    Topics: Aging; Amino Acids; Animals; Cysteine; Diet; Glutamine; Ornithine; Proline; Rats; Rats, Wistar; Threonine; Tyrosine

1994
In vitro effect of hormones and growth factors on the incorporation of [3H]leucine, [35S]sulfate and [3H]proline by chondrocytes of aging mice.
    Mechanisms of ageing and development, 1993, Dec-31, Volume: 72, Issue:3

    Topics: Aging; Animals; Autoradiography; Cartilage, Articular; Collagen; Dose-Response Relationship, Drug; Glycosaminoglycans; Growth Substances; Hormones; Leucine; Male; Mice; Mice, Inbred ICR; Proline; Proteins; Sulfates; Sulfur Radioisotopes; Time Factors; Tritium

1993
In vivo phosphorylation sites in fetal and adult rat tau.
    The Journal of biological chemistry, 1993, Dec-05, Volume: 268, Issue:34

    Topics: Aging; Amino Acid Sequence; Animals; Brain; Cyanogen Bromide; Endopeptidases; Fetus; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Proline; Rats; tau Proteins

1993
Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Aging; Cartilage, Articular; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblast Growth Factor 2; Hydroxyproline; Insulin-Like Growth Factor I; Kinetics; Mitosis; Organ Culture Techniques; Proline; Proteoglycans; Sulfates; Sulfur Radioisotopes; Tritium

1994
Cross-sectional and longitudinal analyses of stimulated parotid salivary constituents in healthy, different-aged subjects.
    Journal of gerontology, 1993, Volume: 48, Issue:5

    Topics: Adult; Aged; Aging; Analysis of Variance; Cross-Sectional Studies; Female; Humans; Lactoferrin; Longitudinal Studies; Male; Middle Aged; Parotid Gland; Potassium; Proline; Proteins; Saliva; Sodium

1993
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve.
    Brain research. Developmental brain research, 1993, Mar-19, Volume: 72, Issue:1

    Topics: Action Potentials; Aging; Animals; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Myelin Sheath; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Mutant Strains; Receptors, GABA-A; Reference Values

1993
Regulation of intestinal nutrient transport is impaired in aged mice.
    The Journal of nutrition, 1993, Volume: 123, Issue:3

    Topics: Aging; Amino Acids; Animals; Aspartic Acid; Biological Transport; Dietary Carbohydrates; Dietary Proteins; Fructose; Glucose; Intestinal Absorption; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Organ Size; Phlorhizin; Proline

1993
Proline, ascorbic acid, or thioredoxin affect jaundice and mortality in Long Evans cinnamon rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: Aging; Animals; Antioxidants; Ascorbic Acid; Copper; Diet; Infusion Pumps, Implantable; Jaundice; Male; Proline; Rats; Rats, Inbred Strains; Thioredoxins

1995
Cell proliferation of human fibroblasts and osteoblasts in osteogenesis imperfecta: influence of age.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:11

    Topics: Aging; Cell Division; Cells, Cultured; Collagen; Humans; Osteoblasts; Osteoclasts; Osteogenesis Imperfecta; Proline; Protein Biosynthesis

1995
A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart.
    Human molecular genetics, 1995, Volume: 4, Issue:10

    Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Brain; Chromosome Mapping; Chromosomes, Artificial, Yeast; Chromosomes, Human, Pair 21; Cloning, Molecular; DNA Primers; DNA-Binding Proteins; Down Syndrome; Exons; Gene Expression; Gene Expression Regulation; Genetic Markers; Heart; Heart Defects, Congenital; Humans; Intellectual Disability; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Muscle Proteins; Myocardium; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Proteins; Rats; Restriction Mapping; Sequence Homology, Amino Acid; Signal Transduction; Transcription, Genetic

1995
Fast axonal transport rates are unchanged in 6- and 24-month F344 rats.
    Brain research, 1995, Nov-13, Volume: 699, Issue:1

    Topics: Age Factors; Aging; Animals; Axons; Male; Proline; Rats; Rats, Inbred F344; Sciatic Nerve; Time Factors

1995
Identification of two cDNA clones encoding small proline-rich proteins expressed in sheep ruminal epithelium.
    The Biochemical journal, 1996, Jul-01, Volume: 317 ( Pt 1)

    Topics: Aging; Amino Acid Sequence; Animals; Animals, Newborn; Base Sequence; Cloning, Molecular; Cornified Envelope Proline-Rich Proteins; DNA, Complementary; Epithelium; Gene Expression; In Situ Hybridization; Membrane Proteins; Molecular Sequence Data; Proline; Proteins; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Rumen; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sheep; Species Specificity; Tissue Distribution

1996
Ontogenetic development of proline intestinal transport in the domestic fowl.
    British poultry science, 1996, Volume: 37, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Biological Transport, Active; Body Weight; Chickens; Ileum; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Jejunum; Kinetics; Leucine; Male; Mercuric Chloride; Proline

1996
Comparison of 5-hydroxy-2-amino valeric acid with carbonyl group content as a marker of oxidized protein in human and mouse liver tissues.
    Free radical biology & medicine, 1996, Volume: 21, Issue:4

    Topics: Aging; Amino Acids; Animals; Arginine; Biomarkers; Carboxylic Acids; Cytosol; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Proline; Proteins; Regression Analysis; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion

1996
Arginine degradation in developing porcine enterocytes.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Aging; Animals; Animals, Newborn; Animals, Suckling; Arginine; Cells, Cultured; Citrulline; Cyclohexanecarboxylic Acids; Intestinal Mucosa; Jejunum; Nitric Oxide Synthase; Nitroarginine; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Swine; Valine; Weaning

1996
The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: evidence for a synergistic interaction between group 1 and group 2 receptors.
    Neuropharmacology, 1996, Volume: 35, Issue:12

    Topics: Aging; Animals; Animals, Newborn; Brain; Cloning, Molecular; Colforsin; Cyclic AMP; Cycloleucine; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Humans; Inositol; Kinetics; Neuroprotective Agents; Phosphatidylinositols; Proline; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Resorcinols; Second Messenger Systems

1996
Ageing increases growth factor-induced inorganic pyrophosphate elaboration by articular cartilage.
    Mechanisms of ageing and development, 1994, Volume: 75, Issue:1

    Topics: Aging; Animals; Cartilage, Articular; Culture Media; Diphosphates; Epidermal Growth Factor; Growth Substances; Proline; Pyrophosphatases; Swine; Thymidine; Transforming Growth Factor beta

1994
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
    The Journal of nutrition, 1997, Volume: 127, Issue:5

    Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning

1997
Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Arginine; Carbon Radioisotopes; Citrulline; Female; Intestinal Mucosa; Male; Mitochondria; Models, Biological; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Radioisotope Dilution Technique; Rats; Swine

1997
Development and organization of ocular dominance bands in primary visual cortex of the sable ferret.
    The Journal of comparative neurology, 1999, May-03, Volume: 407, Issue:2

    Topics: Aging; Animals; Axonal Transport; Dominance, Cerebral; Ferrets; Functional Laterality; Proline; Thalamus; Tritium; Vision, Ocular; Visual Cortex; Visual Pathways; Visual Perception; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate

1999
Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling.
    The Biochemical journal, 1999, May-15, Volume: 340 ( Pt 1)

    Topics: Aging; Amino Acid Substitution; Binding Sites; Calcium; Connective Tissue; Ectopia Lentis; Endoplasmic Reticulum; Exons; Extracellular Matrix Proteins; Fibrillin-1; Fibrillins; Humans; Metalloendopeptidases; Microfilament Proteins; Microscopy, Electron; Molecular Weight; Peptide Fragments; Polymers; Proline; Protein Processing, Post-Translational; Recombinant Proteins

1999
Effect of the group II metabotropic glutamate agonist, 2R,4R-APDC, varies with age, layer, and visual experience in the visual cortex.
    Journal of neurophysiology, 1999, Volume: 82, Issue:1

    Topics: Aging; Animals; Cats; Darkness; Excitatory Amino Acid Agonists; Light; Neurons; Proline; Reaction Time; Receptors, Metabotropic Glutamate; Visual Cortex; Visual Perception

1999
DNA sequence variants of p53: cancer and aging.
    American journal of human genetics, 1999, Volume: 65, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline

1999
Free 4-hydroxyproline content in serum of bedridden aged people is elevated due to fracture.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Bed Rest; Bone Density; Bone Resorption; Calibration; Female; Fractures, Bone; Humans; Hydroxyproline; Immobilization; Luminescent Measurements; Male; Middle Aged; Proline

2000
Intestinal transport of monosaccharides and amino acids during postnatal development of mink.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:6

    Topics: Aging; Amino Acids; Animals; Aspartic Acid; Body Weight; Female; Fructose; Glucose; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Lysine; Male; Methionine; Microvilli; Mink; Monosaccharides; Proline

2000
Chronic but not acute energy restriction increases intestinal nutrient transport in mice.
    The Journal of nutrition, 2001, Volume: 131, Issue:3

    Topics: Adaptation, Biological; Aging; Analysis of Variance; Animals; Biological Transport; Diet, Reducing; Energy Intake; Food Deprivation; Fructose; Glucose; Intestinal Absorption; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Organ Size; Proline; Time Factors

2001
A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity.
    European journal of endocrinology, 2001, Volume: 144, Issue:3

    Topics: Aging; Alanine; Alleles; Amino Acid Substitution; Anthropometry; Australia; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Genotype; Humans; Hyperlipidemias; Male; Middle Aged; Obesity; Odds Ratio; Polymorphism, Genetic; Proline; Receptors, Cytoplasmic and Nuclear; Sex Characteristics; Smoking; Thinness; Transcription Factors; Triglycerides; White People

2001
[Hydroxylation of skin collagen in relation to age: analyses of the human skin].
    Aktuelle Gerontologie, 1977, Volume: 7, Issue:5

    Topics: Adult; Age Factors; Aging; Collagen; Female; Humans; Hydrolysis; Hydroxylation; Hydroxylysine; Hydroxyproline; Lysine; Middle Aged; Proline; Skin

1977
Rapid axoplasmic transport in dystrophic mice.
    Journal of neurochemistry, 1977, Volume: 29, Issue:5

    Topics: Aging; Animals; Axonal Transport; Female; In Vitro Techniques; Methionine; Mice; Muscular Dystrophy, Animal; Nerve Tissue Proteins; Proline; Sciatic Nerve; Species Specificity; Spinal Cord

1977
The effect of protein-energy malnutrition on the development of bones in newborn rats.
    The Journal of nutrition, 1979, Volume: 109, Issue:8

    Topics: Aging; Animals; Animals, Newborn; Bone and Bones; Bone Development; Calcium; Collagen; Female; Hydroxyproline; Male; Mandible; Proline; Protein-Energy Malnutrition; Rats

1979
H3-proline study of aging periodontal ligament matrix formation: comparison between matrices adjacent to either cemental or bone surfaces.
    Journal of periodontal research, 1977, Volume: 12, Issue:4

    Topics: Aging; Animals; Bone Matrix; Fibroblasts; Maxilla; Mice; Periodontal Ligament; Proline

1977
Age-related changes in the flight muscle mitochondria from the blowfly Sarcophaga bullata.
    Journal of gerontology, 1976, Volume: 31, Issue:3

    Topics: Aging; Animals; Cytochromes; Diptera; Energy Metabolism; Female; Glycerophosphates; Hydrogen Peroxide; Male; Mitochondria, Muscle; Mitochondrial Swelling; NAD; Oxygen Consumption; Proline; Pyruvates

1976
Collagen metabolism in skin and periodontal ligament of rats: effect of aging and irradiation.
    Journal of dental research, 1978, Volume: 57, Issue:2

    Topics: Aging; Animals; Collagen; Fast Neutrons; Hydroxyproline; Male; Periodontal Ligament; Proline; Rats; Skin; Tritium

1978
Autoradiographic visualization of 3H-proline incorporation into the gingival epithelium of rats of different age groups.
    Aichi Gakuin Daigaku Shigakkai shi, 1977, Volume: 15, Issue:2

    Topics: Aging; Animals; Autoradiography; Epithelium; Gingiva; Proline; Rats; Tritium

1977
In-vivo incorporation of [3H]-proline into rabbit dental pulp collagen.
    Archives of oral biology, 1979, Volume: 24, Issue:8

    Topics: Aging; Animals; Collagen; Dental Pulp; Hydroxyproline; Incisor; Molar; Proline; Rabbits

1979
Preliminary autohistoradiographic studies about the possible participation of the secretory ameloblasts during the enamel maturation.
    Cellular and molecular biology, including cyto-enzymology, 1979, Volume: 24, Issue:2

    Topics: Aging; Ameloblasts; Animals; Autoradiography; Dental Enamel; Histocytochemistry; Incisor; Mice; Proline; Tritium

1979
Changes of X-prolyl dipeptidyl-aminopeptidase activity in developing rat brain.
    Experientia, 1979, Oct-15, Volume: 35, Issue:10

    Topics: Aging; Animals; Brain; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Proline; Rats; Substrate Specificity

1979
Unresponsiveness of cartilage to serum somatomedins--further observations.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:6

    Topics: Aging; Animals; Cartilage; Humans; Male; Proline; Rats; Ribs; Somatomedins

1979
Studies on the rat glomerular basement membrane: age-related changes in composition.
    Archives of biochemistry and biophysics, 1978, Jan-30, Volume: 185, Issue:2

    Topics: Aging; Amino Acids; Animals; Basement Membrane; Female; Glycine; Hydroxylysine; Hydroxyproline; Kidney Glomerulus; Lysine; Male; Proline; Rats; Sodium Dodecyl Sulfate

1978
The effect of age on amino acid composition of human skin collagen.
    Journal of gerontology, 1978, Volume: 33, Issue:4

    Topics: Adult; Age Factors; Aged; Aging; Aldehydes; Amino Acids; Child; Collagen; Cysteine; Female; Humans; Hydroxylysine; Hydroxyproline; Infant, Newborn; Lysine; Middle Aged; Proline; Skin

1978
Serum levels of proline imino-peptidase in normal adults and children.
    Clinica chimica acta; international journal of clinical chemistry, 1977, Dec-15, Volume: 81, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Aminopeptidases; Child; Child, Preschool; Female; Humans; Infant; Male; Middle Aged; Proline; Reference Values

1977
[On the metabolic heterogenity of the cartilage tissue (author's transl)].
    Zeitschrift fur Alternsforschung, 1976, Volume: 31, Issue:1

    Topics: Aging; Animals; Cartilage; Cartilage, Articular; DNA; Proline; Rabbits; Rats; Ribs; Sternum; Sulfates; Trachea

1976
Arterial elastin synthesis in the young chick.
    Biochimica et biophysica acta, 1976, Sep-06, Volume: 442, Issue:3

    Topics: Aging; Animals; Aorta, Thoracic; Chickens; DNA; Elastin; Molecular Weight; Muscles; Myocardium; Proline; Valine

1976
Alterations in proline metabolic enzymes with mammalian development.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:10

    Topics: Aging; Animals; Carboxylic Acids; Female; Kidney; Kinetics; Leucine; Liver; Mitochondria, Liver; Organ Specificity; Oxidoreductases; Oxygenases; Pregnancy; Proline; Pyrroles; Rats; Stereoisomerism; Valine

1976
Blood-brain barrier: selective changes during maturation.
    Neuroscience, 1976, Volume: 1, Issue:2

    Topics: Aging; Animals; Blood-Brain Barrier; Cerebellum; Cerebral Cortex; Chick Embryo; Chickens; Glucose; Inulin; Proline; Structure-Activity Relationship; Tectum Mesencephali; Tyrosine

1976
Topographic labelling methods using [3H]-proline autoradiography in assessment of ageing parodontal bone in the mouse.
    Archives of oral biology, 1976, Volume: 21, Issue:12

    Topics: Aging; Alveolar Process; Animals; Autoradiography; Collagen; Female; Male; Mice; Osteogenesis; Periosteum; Proline; Tritium

1976
Changes in guinea-pig dermal collagen during development.
    Biochemical Society transactions, 1975, Volume: 3, Issue:1

    Topics: Aging; Animals; Chromatography, Gel; Collagen; Female; Guinea Pigs; Mercaptoethanol; Molecular Weight; Osmolar Concentration; Pepsin A; Pregnancy; Proline; Skin

1975
Isolation and characterization of an age-dependent polypeptide from human lens with non-tryptophan fluorescence.
    Experimental eye research, 1975, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Amino Acids; Child; Child, Preschool; Chromatography, Ion Exchange; Crystallins; Electrophoresis, Paper; Fluorescence; Glycine; Humans; Hydrolysis; Infant; Middle Aged; Molecular Weight; Peptides; Proline; Spectrophotometry; Tryptophan

1975
Regulatory characteristics of amino acid transport in newborn rat renal cortex cells.
    Biochimica et biophysica acta, 1976, Mar-19, Volume: 426, Issue:3

    Topics: Aging; Amino Acids; Aminoisobutyric Acids; Anaerobiosis; Animals; Animals, Newborn; Biological Transport, Active; Cycloheximide; Cycloleucine; Dactinomycin; Dinitrophenols; Glycine; In Vitro Techniques; Kidney Cortex; Kinetics; Ouabain; Proline; Puromycin; Rats; Sodium

1976
Selection of intrinsic horizontal connections in the visual cortex by correlated neuronal activity.
    Science (New York, N.Y.), 1992, Jan-10, Volume: 255, Issue:5041

    Topics: Aging; Animals; Autoradiography; Axonal Transport; Carbon Radioisotopes; Cats; Deoxyglucose; Dominance, Cerebral; Neurons; Proline; Strabismus; Tritium; Visual Cortex

1992
Intestinal amino acid and monosaccharide transport in suckling pigs fed milk replacers with different sources of carbohydrate.
    The Journal of nutrition, 1992, Volume: 122, Issue:12

    Topics: Aging; Amino Acids; Animals; Animals, Suckling; Biological Transport; Dietary Carbohydrates; Female; Food, Formulated; Fructose; Galactose; Glucose; Intestinal Absorption; Intestinal Mucosa; Lactose; Leucine; Male; Milk; Monosaccharides; Polysaccharides; Proline; Sucrose; Swine; Weight Gain

1992
A reconsideration of the primary visual system of the turtle Emys orbicularis.
    Journal fur Hirnforschung, 1992, Volume: 33, Issue:4-5

    Topics: Afferent Pathways; Aging; Animals; Brain; Geniculate Bodies; Horseradish Peroxidase; Hypothalamus; Mesencephalon; Nerve Fibers; Proline; Retina; Superior Colliculi; Thalamus; Tritium; Turtles; Visual Pathways

1992
Age-related changes in glomerular volume and hydroxyproline content in rat and human.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:12

    Topics: Adolescent; Adult; Aged; Aging; Animals; Basement Membrane; Child; Child, Preschool; Humans; Hydroxyproline; Infant; Kidney Glomerulus; Male; Middle Aged; Proline; Rats; Rats, Inbred F344

1992
Ontogeny of taurocholate accumulation in the terminal ileal mucosal cells of young chicks.
    Poultry science, 1992, Volume: 71, Issue:2

    Topics: Aging; Animals; Azides; Bile Acids and Salts; Biological Transport, Active; Chickens; Cholestyramine Resin; Culture Techniques; Dinitrophenols; Duodenum; Ileum; Indicators and Reagents; Intestinal Absorption; Intestinal Mucosa; Male; Proline; Sodium Azide; Taurocholic Acid

1992
Transport of L-proline and alpha-methyl-D-glucoside by chicken proximal cecum during development.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 1

    Topics: Aging; Animals; Biological Transport; Cecum; Chickens; In Vitro Techniques; Intestinal Absorption; Kinetics; Male; Mannitol; Methylglucosides; Muscle Development; Muscle, Smooth; Proline

1991
Age-related changes in rates of protein synthesis and degradation in rat tissues.
    Mechanisms of ageing and development, 1991, Jun-28, Volume: 59, Issue:3

    Topics: Aging; Animals; Body Weight; Male; Organ Size; Proline; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Lew

1991
Age-related changes in collagen synthesis and degradation in rat tissues. Importance of degradation of newly synthesized collagen in regulating collagen production.
    The Biochemical journal, 1991, Jun-01, Volume: 276 ( Pt 2)

    Topics: Aging; Animals; Carbon Radioisotopes; Collagen; Heart; Hydroxyproline; Lung; Male; Muscle Development; Proline; Rats; Rats, Inbred Lew; Skin

1991
Long-term physical exercise retards trabecular bone loss in lumbar vertebrae of aging female mice.
    Calcified tissue international, 1990, Volume: 46, Issue:2

    Topics: Acid Phosphatase; Aging; Alkaline Phosphatase; Animals; Autoradiography; Bone Diseases, Metabolic; Calcium; Corticosterone; Female; Lumbar Vertebrae; Mice; Osteoporosis; Physical Conditioning, Animal; Proline; Time Factors; Tritium

1990
[3H]nipecotic acid binding to gamma-aminobutyric acid uptake sites in postmortem human brain.
    Journal of neurochemistry, 1990, Volume: 55, Issue:1

    Topics: Aged; Aging; Binding Sites; Brain; Cadaver; Female; gamma-Aminobutyric Acid; Hippocampus; Humans; Huntington Disease; Male; Middle Aged; Nipecotic Acids; Postmortem Changes; Proline; Sodium; Tritium

1990
Ontogenetic development of nutrient transporters in bullfrog intestine.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Aging; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Colon; Glucose; Intestinal Mucosa; Intestine, Small; Metamorphosis, Biological; Microvilli; Monosaccharide Transport Proteins; Proline; Rana catesbeiana; Species Specificity

1990
Ontogenetic development of transporter regulation in bullfrog intestine.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: Aging; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Colon; Glucose; Intestine, Small; Kinetics; Metamorphosis, Biological; Monosaccharide Transport Proteins; Proline; Rana catesbeiana

1990
Collagen synthesis in explants from rat intestine.
    Biochimica et biophysica acta, 1989, Dec-08, Volume: 993, Issue:2-3

    Topics: Aging; Animals; Biological Transport; Collagen; Colon; Ileum; Intestinal Mucosa; Kinetics; Male; Microbial Collagenase; Proline; Rats; Rats, Inbred Strains

1989
Characteristics of L-proline and sodium transport in renal brush border membranes isolated from 7-day-old and adult rats.
    Bioscience reports, 1989, Volume: 9, Issue:6

    Topics: Aging; Animals; Biological Transport; Cell Fractionation; In Vitro Techniques; Kidney; Male; Microvilli; Osmosis; Proline; Rats; Rats, Inbred Strains; Sodium

1989
Pyrroline-5-carboxylate reductase and proline oxidase activity in the neonatal pig.
    The Journal of nutrition, 1989, Volume: 119, Issue:12

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Muscles; Nutritional Requirements; Oxidoreductases Acting on CH-NH Group Donors; Proline; Proline Oxidase; Pyrroline Carboxylate Reductases; Swine; Temperature; Weaning

1989
Postnatal development of corticocortical efferents from area 17 in the cat's visual cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Cats; Efferent Pathways; Geniculate Bodies; Proline; Tritium; Visual Cortex

1989
Further studies on the nutritional factors affecting the urinary excretion of acid-soluble peptides in rats.
    The British journal of nutrition, 1988, Volume: 60, Issue:2

    Topics: Aging; Amino Acids; Animals; Caseins; Dietary Proteins; Leucine; Lysine; Male; Methylhistidines; Nitrogen; Peptides; Proline; Rats; Rats, Inbred Strains; Tryptophan; Valine

1988
Bone turnover in postmenopausal osteoporosis. Effect of calcitonin treatment.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:4

    Topics: Aging; Biomarkers; Bone Resorption; Calcitonin; Calcium-Binding Proteins; Female; Humans; Hydroxyproline; Menopause; Middle Aged; Minerals; Osteocalcin; Osteoporosis; Proline

1988
Decline of fibroblast chemotaxis with age of donor and cell passage number.
    Collagen and related research, 1988, Volume: 8, Issue:1

    Topics: Aged; Aging; Cell Division; Cell Survival; Cells, Cultured; Chemotaxis; Child, Preschool; Collagen; Female; Fibroblasts; Fibronectins; Fluorescent Antibody Technique; Humans; Infant; Laminin; Male; Progeria; Proline; Protein Biosynthesis; Thymidine

1988
Bilateral pericruciate cortical innervation of the red nucleus in cats with adult or neonatal cerebral hemispherectomy.
    Brain research, 1988, Jun-21, Volume: 453, Issue:1-2

    Topics: Aging; Animals; Autoradiography; Cats; Cerebral Cortex; Cerebral Decortication; Female; Leucine; Male; Neural Pathways; Neuronal Plasticity; Proline; Red Nucleus

1988
The effects of simulated weightlessness on bone maturation.
    Endocrinology, 1987, Volume: 120, Issue:2

    Topics: Aging; Animals; Bone and Bones; Bone Development; Calcium; Male; Organ Size; Proline; Rats; Rats, Inbred Strains; Weightlessness

1987
Stimulation of the hexose monophosphate pathway by pyrroline-5-carboxylate reductase in the lens.
    Experimental eye research, 1985, Volume: 41, Issue:6

    Topics: Aging; Animals; Female; Glucose; Glutamine; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains

1985
Lung collagen and elastin after ozone exposure in vitamin B-6-deficient rats.
    Toxicology letters, 1986, Volume: 30, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Collagen; Connective Tissue; Elastin; Female; Lactation; Lung; Male; Organ Size; Ozone; Pregnancy; Proline; Rats; Rats, Inbred Strains; Vitamin B 6 Deficiency

1986
Identification and characterization of pipecolic acid binding sites in mouse brain.
    Neurochemical research, 1985, Volume: 10, Issue:5

    Topics: Aging; Animals; Binding Sites; Brain; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Pipecolic Acids; Proline; Sodium; Sodium Chloride; Tissue Distribution

1985
Changes in collagen synthesis and degradation during skeletal muscle growth.
    The American journal of physiology, 1985, Volume: 249, Issue:3 Pt 1

    Topics: Aging; Animals; Chickens; Collagen; Hydroxyproline; Hypertrophy; Male; Muscle Development; Muscles; Proline; Tritium

1985
The alpha-glycerophosphate cycle in Drosophila melanogaster. IV. Metabolic, ultrastructural, and adaptive consequences of alphaGpdh-l "null" mutations.
    The Journal of cell biology, 1974, Volume: 63, Issue:3

    Topics: Adaptation, Biological; Aging; Alleles; Aneuploidy; Chromosome Mapping; Drosophila melanogaster; Genes; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycerolphosphate Dehydrogenase; Glycerophosphates; Heterozygote; Homozygote; L-Lactate Dehydrogenase; Malate Dehydrogenase; Microscopy, Electron; Mitochondria; Muscles; Mutation; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Phenotype; Proline; Pyruvates

1974
Effect of hyperthyroidism and hypothyroidism on collagen metabolism.
    The Journal of laboratory and clinical medicine, 1967, Volume: 69, Issue:6

    Topics: Aging; Animals; Antithyroid Agents; Bone and Bones; Carbon Isotopes; Collagen; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Proline; Rats; Skin; Thyroxine

1967
Significance of the occurrence of transparent skin. A study of histological characteristics and biosynthesis of dermal collagen.
    Annals of the rheumatic diseases, 1967, Volume: 26, Issue:3

    Topics: Aging; Carbon Isotopes; Collagen; Glycosaminoglycans; Humans; Injections, Intradermal; Proline; Skin Diseases

1967
Hydroxyproline and collagen metabolism. Clinical implications.
    Annals of internal medicine, 1965, Volume: 63, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Blood Proteins; Child; Child, Preschool; Collagen; Female; Gelatin; Humans; Hydroxyproline; Hyperparathyroidism; Hyperthyroidism; Infant; Infant, Newborn; Male; Marfan Syndrome; Microbial Collagenase; Middle Aged; Myxedema; Proline; Psoriasis; Scleroderma, Systemic; Triiodothyronine; Urine

1965
The effect of ageing upon collagen metabolism.
    Symposia of the Society for Experimental Biology, 1967, Volume: 21

    Topics: Aging; Animals; Body Weight; Burns; Citrates; Collagen; Cycloheximide; Desoxycorticosterone; Glycine; Hydrocortisone; Hydroxyproline; Liver Glycogen; Male; Microbial Collagenase; Peptide Hydrolases; Phenytoin; Prednisolone; Proline; Puromycin; Rats; Skin; Sodium Chloride; Tissue Extracts

1967
Sex-dependent vascular changes in young, adult, aged, and hypertensive rats.
    The American journal of pathology, 1968, Volume: 53, Issue:1

    Topics: Adenosine Triphosphatases; Aging; Alkaline Phosphatase; Animals; Aorta; Arteries; Arteriosclerosis; Collagen; Female; Histocytochemistry; Hypertension; Male; NAD; Nucleotidases; Proline; Rats; Sex Factors; Tritium

1968
The effect of acute exercise on amino acid incorporation into mitochondria of rabbit tissues.
    Biochimica et biophysica acta, 1969, Aug-20, Volume: 186, Issue:2

    Topics: Adenosine Triphosphate; Adrenocorticotropic Hormone; Aging; Amino Acids; Animals; Brain; Buffers; Carbon Isotopes; Centrifugation, Density Gradient; Hypoxia; Leucine; Male; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxygen; Physical Exertion; Proline; Protein Biosynthesis; Quaternary Ammonium Compounds; Rabbits; Swimming; Testosterone

1969
Differences in properties of newly formed collagen during aging and parabiosis.
    Journal of gerontology, 1972, Volume: 27, Issue:2

    Topics: Aging; Amino Acids; Animals; Blood Proteins; Carbon Isotopes; Chemical Phenomena; Chemistry; Collagen; Connective Tissue; DNA; Fibroblasts; Liver; Male; Microbial Collagenase; Parabiosis; Pepsin A; Proline; Proteins; Rats

1972
Interstitial edema in valvular endocarditis.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Adult; Aged; Aging; Animals; Autoradiography; Collagen; Edema; Endocarditis; Female; Glycosaminoglycans; Heart Valve Diseases; Heart Valves; Humans; Male; Microscopy, Electron; Mitral Valve; Phosphoric Monoester Hydrolases; Proline; Rats; Sulfur Isotopes; Tritium

1969
Biosynthesis of collagen (14C)hydroxyproline and (14C)hydroxylysine during maturation of chick embryos.
    Mechanisms of ageing and development, 1973, Volume: 1, Issue:5

    Topics: Aging; Animals; Carbon Isotopes; Chick Embryo; Collagen; Glutamates; Hydroxylation; Hydroxylysine; Hydroxyproline; Microbial Collagenase; Peptides; Proline; Tibia

1973
Intestinal absorption of some heterocyclic and aromatic amino acids from the ageing gut.
    Experimental gerontology, 1974, Volume: 9, Issue:5-6

    Topics: Aging; Animals; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver; Organ Size; Phenylalanine; Proline; Rats; Tryptophan

1974
An age-dependent determination of lysosomal enzyme activities, as well as the measurements on the incorporation of 14-C-proline and 14-C-glucosamine in a subcutaneously implanted polyether sponge.
    Gerontologia, 1972, Volume: 18, Issue:2

    Topics: Age Factors; Aging; Animals; Carbon Isotopes; Cathepsins; Ethers; Glucosamine; Glucuronidase; Granulation Tissue; Granuloma; Hexosaminidases; Lysosomes; Male; Proline; Rats; Time Factors; Wound Healing

1972
Bioenergetic properties of mitochondria from flight muscle of aging blowflies.
    Archives of biochemistry and biophysics, 1972, Volume: 149, Issue:2

    Topics: Adenosine Diphosphate; Aging; Animals; Cattle; Female; Insecta; Kinetics; Microscopy, Electron; Mitochondria, Muscle; Muscles; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Proline; Pyruvates; Serum Albumin, Bovine

1972
Effect of cortisol treatment on free amino acid levels in rats.
    The Journal of endocrinology, 1973, Volume: 59, Issue:1

    Topics: Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Glycine; Hydrocortisone; Liver; Male; Muscle Proteins; Muscles; Proline; Rats; Serine

1973
The relationship between proline and hydroxyproline urinary excretion in human as an index of collagen catabolism.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Oct-12, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Aging; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Diet; Female; Gelatin; Humans; Hydroxyproline; Infant; Male; Marfan Syndrome; Middle Aged; Paraplegia; Peptides; Proline; Psoriasis; Scleroderma, Systemic

1973
Free amino acids in developing rat retina.
    Journal of neurochemistry, 1974, Volume: 22, Issue:6

    Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine

1974
Synthesis of type I and type II collagen by embryonic chick cartilage.
    Biochemical and biophysical research communications, 1974, May-07, Volume: 58, Issue:1

    Topics: Aging; Animals; Autoradiography; Carbon Radioisotopes; Cartilage; Cartilage, Articular; Chick Embryo; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Collagen; Hydroxylation; Lysine; Proline; Thymidine; Time Factors; Tritium; Uridine

1974
The solubility and synthetic rate of bone collagen in idiopathic osteoporosis.
    Clinical orthopaedics and related research, 1972, Volume: 88

    Topics: Adolescent; Adult; Aging; Bone and Bones; Bone Matrix; Carbon Isotopes; Climacteric; Collagen; DNA; Female; Glucose; Humans; Hydroxyproline; Hyperparathyroidism; Lactates; Male; Middle Aged; Nitrogen; Osteoporosis; Proline; Solubility

1972
Age factor in the formation and metabolism of experimental granulation tissue.
    Journal of gerontology, 1971, Volume: 26, Issue:3

    Topics: Aging; Animals; Cellulose; Collagen; DNA; Granulation Tissue; Hydroxyproline; Irritants; L-Lactate Dehydrogenase; Male; Nitrogen; Oxygen Consumption; Proline; Protein Biosynthesis; Rats; RNA; Tritium

1971
The induction of osteopetrotic changes in hypophysectomized, thyroparathyroidectomized and intact rats of various ages.
    Endocrinology, 1971, Volume: 89, Issue:6

    Topics: Aging; Animals; Body Weight; Bone Development; Calcium; Calcium, Dietary; Epithelium; Growth Hormone; Hematocrit; Hypercalcemia; Hypophysectomy; Male; Osteopetrosis; Parathyroid Glands; Parathyroid Hormone; Pituitary Gland; Proline; Rats; Skull; Thyroid Gland; Thyroxine; Tritium

1971
The ontogeny of amino acid transport in rat kidney. I. Effect on distribution ratios and intracellular metabolism of proline and glycine.
    Biochimica et biophysica acta, 1971, Dec-03, Volume: 249, Issue:2

    Topics: Aging; Aminoisobutyric Acids; Animals; Animals, Newborn; Biological Transport; Carbon Dioxide; Carbon Isotopes; Glycine; Hydrogen-Ion Concentration; Hydroxyproline; Kidney; Kinetics; Proline; Rats; Temperature

1971
An autoradiographic study of H 3 -proline utilization by aging mouse skeletel tissues. II. Cartilage cell compartments.
    Experimental gerontology, 1971, Volume: 6, Issue:6

    Topics: Aging; Animals; Autoradiography; Cartilage; Cartilage, Articular; Epiphyses; Femur; Mice; Proline; Radiography; Tritium

1971
An autoradiographic study of He-proline utilization by aging mouse skeletal tissues. I. Bone cell compartments.
    Journal of gerontology, 1971, Volume: 26, Issue:3

    Topics: Aging; Animals; Autoradiography; Bone and Bones; Computers; Femur; Mice; Osteoblasts; Periosteum; Proline; Statistics as Topic; Tritium

1971
An autoradiographic study of 3 H-proline utilization by aging mouse skeletal tissues. 3. Estimation and comparison of the turnover times of different cell compartments.
    Gerontologia, 1971, Volume: 17, Issue:5

    Topics: Aging; Animals; Autoradiography; Bone and Bones; Female; Kinetics; Mice; Mice, Inbred Strains; Osteoblasts; Proline; Tritium

1971
[Aging processes in collagen (author's transl)].
    Altern und Entwicklung. Aging and development, 1971, Volume: 3

    Topics: Aging; Animals; Collagen; Connective Tissue; Connective Tissue Cells; Densitometry; Glycine; Humans; Male; Microscopy, Electron; Muscles; Peptides; Proline; Rabbits; Rats; Temperature

1971
Protocollagen proline hydroxylase activity in the skin of normal human subjects and of patients with scleroderma.
    Scandinavian journal of clinical and laboratory investigation, 1969, Volume: 23, Issue:3

    Topics: Adult; Aging; Animals; Biopsy; Carbon Isotopes; Chick Embryo; Collagen; Fetus; Humans; Infant, Newborn; Middle Aged; Mixed Function Oxygenases; Proline; Rats; Scleroderma, Systemic; Skin

1969
Biosynthesis of collagen fibres.
    Clinical science, 1970, Volume: 38, Issue:2

    Topics: Aging; Aspartic Acid; Collagen; Galactose; Glucose; Glutamates; Glycoproteins; Lysine; Proline

1970
A method for studying collagen biosynthesis in human skin biopsies in vitro.
    Biochimica et biophysica acta, 1970, Mar-24, Volume: 201, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Ampicillin; Ascorbic Acid; Biopsy; Buffers; Carbon Isotopes; Child; Child, Preschool; Collagen; Glucose; Humans; Hydrogen-Ion Concentration; Hydroxyproline; In Vitro Techniques; Iron; Kinetics; Methods; Middle Aged; Mixed Function Oxygenases; Nitrogen; Oxygen; Phosphates; Proline; Skin; Time Factors

1970
Degradation and turnover of collagen in the mouse skin and the effect of whole body x-irradiation.
    Biochimica et biophysica acta, 1970, Volume: 208, Issue:3

    Topics: Aging; Animals; Collagen; Injections, Intraperitoneal; Male; Metabolism; Mice; Proline; Radiation Effects; Skin; Sodium Chloride; Solubility; Time Factors; Tritium

1970
Bone collagen metabolism in aging rats.
    Israel journal of medical sciences, 1971, Volume: 7, Issue:3

    Topics: Aging; Animals; Bone and Bones; Calcification, Physiologic; Collagen; Proline; Rats; Tritium

1971
Autoradiographic investigation of calvarial growth in the rat.
    The American journal of anatomy, 1968, Volume: 123, Issue:2

    Topics: Aging; Animals; Autoradiography; Bone Resorption; Male; Methods; Osteogenesis; Proline; Rats; Skull; Tibia; Tritium

1968
The synthesis of collagen during the development of Xenopus laevis.
    Developmental biology, 1968, Volume: 18, Issue:4

    Topics: Age Factors; Aging; Animals; Anura; Collagen; Embryo, Nonmammalian; Fibroblasts; Hydroxyproline; Mixed Function Oxygenases; Peptide Biosynthesis; Proline; Protein Biosynthesis; Tritium

1968
The quantitative measurement of bone resorption and balance in vitro by analysis of hydroxyproline metabolism.
    Calcified tissue research, 1968

    Topics: Aging; Animals; Biological Transport; Bone and Bones; Bone Resorption; Carbon Isotopes; Collagen; Culture Techniques; Hydroxyproline; Proline; Rats

1968
Developmental pattern of some intestinal transport mechanisms in newborns rats and mice.
    The American journal of physiology, 1969, Volume: 216, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Isotopes; Colon; Glucose; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Mice; Proline; Rats

1969
The lens capsule. Sugar and amino acid composition.
    The Journal of biological chemistry, 1969, Apr-25, Volume: 244, Issue:8

    Topics: Aging; Amino Acids; Animals; Carbohydrates; Cattle; Collagen; Fucose; Galactose; Glucosamine; Glucose; Glycine; Hexosamines; Hydrogen-Ion Concentration; Hydroxyproline; Kidney Glomerulus; Lens, Crystalline; Lysine; Mannose; Membranes; Neuraminic Acids; Peptides; Proline; Solubility; Uronic Acids; Vibration

1969
[Studies on the chemical composition of vascular wall. I. Collagen, proline and hydroxyproline of the aortic wall in the process of physiological aging].
    Polskie Archiwum Medycyny Wewnetrznej, 1965, Volume: 35, Issue:6

    Topics: Aging; Animals; Aorta; Chemical Phenomena; Chemistry; Collagen; Hydroxyproline; Proline; Rats

1965
Biochemistry of the developing rat brain. 8. Changes in the ribosomal system and nuclear RNA's.
    Biochimica et biophysica acta, 1966, Dec-21, Volume: 129, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell Nucleus; Hydrogen-Ion Concentration; Lysine; Phenylalanine; Proline; Protein Biosynthesis; Rats; Ribosomes; RNA; RNA, Messenger; Ultracentrifugation; Ultraviolet Rays

1966