proglumide has been researched along with Pain, Postoperative in 5 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients who reported mild postoperative pain, we evoked a nocebo response, a phenomenon equal but opposite to placebo." | 2.68 | Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide. ( Amanzio, M; Benedetti, F; Casadio, C; Maggi, G; Oliaro, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benedetti, F | 2 |
| Amanzio, M | 2 |
| Maggi, G | 2 |
| Casadio, C | 1 |
| Oliaro, A | 1 |
| Lehmann, KA | 1 |
| Schlüsener, M | 1 |
| Arabatsis, P | 1 |
| Lavigne, GJ | 1 |
| Hargreaves, KM | 1 |
| Schmidt, EA | 1 |
| Dionne, RA | 1 |
| Pagnoni, B | 1 |
| Ortalli, G | 1 |
| Rovati, LC | 1 |
| Tiengo, M | 1 |
4 trials available for proglumide and Pain, Postoperative
| Article | Year |
|---|---|
Potentiation of placebo analgesia by proglumide.
Topics: Double-Blind Method; Drug Synergism; Female; Humans; Male; Middle Aged; Pain, Postoperative; Placebo | 1995 |
Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide.
Topics: Analgesics, Non-Narcotic; Cholecystokinin; Double-Blind Method; Female; Humans; Hyperalgesia; Male; | 1997 |
Failure of proglumide, a cholecystokinin antagonist, to potentiate clinical morphine analgesia. A randomized double-blind postoperative study using patient-controlled analgesia (PCA).
Topics: Adult; Cholecystokinin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Syner | 1989 |
Proglumide potentiates morphine analgesia for acute postsurgical pain.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Synergism; Female; Glutamine; Humans; Male; Molar, | 1989 |
1 other study available for proglumide and Pain, Postoperative
| Article | Year |
|---|---|
[Possible potentiation of morphine analgesia by proglumide].
Topics: Adolescent; Adult; Drug Synergism; Drug Therapy, Combination; Female; Glutamine; Humans; Middle Aged | 1988 |