Page last updated: 2024-11-03

proglumide and Obesity

proglumide has been researched along with Obesity in 4 studies

Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Loxiglumide was administered intravenously in a dose of 10 mg/kg ideal weight/h."2.68Satiety effects of the type A CCK receptor antagonist loxiglumide in lean and obese women. ( Jansen, JB; Lamers, CB; Lieverse, RJ; Masclee, AA; Rovati, LC, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Little, TJ1
Horowitz, M1
Feinle-Bisset, C1
Lieverse, RJ1
Masclee, AA1
Jansen, JB1
Rovati, LC1
Lamers, CB1
Niederau, C2
Meereis-Schwanke, K2
Klonowski-Stumpe, H2
Herberg, L2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute[NCT02808546]342 participants (Actual)Observational2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for proglumide and Obesity

ArticleYear
Role of cholecystokinin in appetite control and body weight regulation.
    Obesity reviews : an official journal of the International Association for the Study of Obesity, 2005, Volume: 6, Issue:4

    Topics: Animals; Appetite; Body Weight; Cholecystokinin; Digestive System Physiological Phenomena; Energy In

2005

Trials

1 trial available for proglumide and Obesity

ArticleYear
Satiety effects of the type A CCK receptor antagonist loxiglumide in lean and obese women.
    Biological psychiatry, 1995, Mar-01, Volume: 37, Issue:5

    Topics: Adult; Appetite; Double-Blind Method; Female; Humans; Hunger; Infusions, Intravenous; Middle Aged; O

1995

Other Studies

2 other studies available for proglumide and Obesity

ArticleYear
CCK-resistance in Zucker obese versus lean rats.
    Regulatory peptides, 1997, Jun-18, Volume: 70, Issue:2-3

    Topics: Amylases; Animals; Capsaicin; Cholecystokinin; Eating; Female; Injections, Subcutaneous; Male; Obesi

1997
Long-term effects of CCK-agonist and -antagonist on food intake and body weight in Zucker lean and obese rats.
    Peptides, 1998, Volume: 19, Issue:2

    Topics: Animals; Body Weight; Ceruletide; Cholecystokinin; Drug Resistance; Eating; Female; Male; Obesity; O

1998