proglumide has been researched along with Muscle Relaxation in 5 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 5.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 1.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| "New proglumide peptides were synthesized and their inhibitory activity against the cholecystokinin (CCK)-induced relaxation was tested in duodenal circular muscles of hogs in order to locate the active moiety." | 1.27 | Proglumide peptides and CCK antagonistic action in hog duodenal circular muscle. ( Kimura, I; Kimura, M; Kondoh, T, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kishimoto, S | 1 |
| Machino, H | 1 |
| Kobayashi, H | 1 |
| Haruma, K | 1 |
| Kajiyama, G | 1 |
| Miyoshi, A | 1 |
| Fujii, K | 1 |
| Mesquita, MA | 1 |
| Thompson, DG | 1 |
| Troncon, LE | 1 |
| D'Amato, M | 3 |
| Rovati, LC | 1 |
| Barlow, J | 1 |
| Clavé, P | 1 |
| González, A | 1 |
| Moreno, A | 1 |
| López, R | 1 |
| Farré, A | 1 |
| Cussó, X | 1 |
| Azpiroz, F | 1 |
| Lluís, F | 1 |
| Zerbib, F | 1 |
| Bruley Des Varannes, S | 1 |
| Scarpignato, C | 1 |
| Leray, V | 1 |
| Rozé, C | 1 |
| Galmiche, JP | 1 |
| Kimura, I | 1 |
| Kondoh, T | 1 |
| Kimura, M | 1 |
2 trials available for proglumide and Muscle Relaxation
| Article | Year |
|---|---|
Effect of cholecystokinin-A receptor blockade on lipid-induced gastric relaxation in humans.
Topics: Adult; Cross-Over Studies; Dietary Fats; Double-Blind Method; Fasting; Fat Emulsions, Intravenous; F | 1997 |
Endogenous cholecystokinin in postprandial lower esophageal sphincter function and fundic tone in humans.
Topics: Adult; Cholecystokinin; Duodenum; Eating; Enteral Nutrition; Esophagogastric Junction; Fasting; Fema | 1998 |
3 other studies available for proglumide and Muscle Relaxation
| Article | Year |
|---|---|
Inhibitory action of CCK-OP on rat proximal colon.
Topics: Acetylcholine; Animals; Atropine; Colon; Fasting; Hexamethonium; Hexamethonium Compounds; Muscle Con | 1994 |
Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors.
Topics: Adult; Cholecystokinin; Cholestyramine Resin; Eating; Electric Stimulation; Esophagogastric Junction | 1998 |
Proglumide peptides and CCK antagonistic action in hog duodenal circular muscle.
Topics: Animals; Cholecystokinin; Duodenum; Female; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; | 1987 |