proglumide has been researched along with Muscle Contraction in 57 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 5.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| "Release of [3H]-acetylcholine (3H-ACh) and muscle contractions in response to cholecystokinin (CCK) were measured and recorded simultaneously from isolated guinea-pig gallbladder." | 3.68 | Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladder. ( Mantovani, P; Milenov, K; Rakovska, A; Sgaragli, G; Valoti, M, 1993) |
| "Proglumide did not increase contractile activity of the omasum, abomasum and duodenum or the plasma concentration of immunoreactive cholecystokinin (CCK)." | 1.34 | Effect of intravenous infusion of proglumide on ruminal motility in conscious sheep (Ovis aries). ( Onaga, T, 2007) |
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 1.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| " Both antagonists caused a rightward shift of the dose-response curve for CCK-8s on the monkey iris sphincter." | 1.28 | Cholecystokinin contracts isolated human and monkey iris sphincters; a study with CCK receptor antagonists. ( Almegård, B; Bill, A; Stjernschantz, J, 1992) |
| "Oral treatment with loxiglumide increased stool weight 72% (P less than 0." | 1.28 | Role of CCK in regulation of pancreaticobiliary functions and GI motility in humans: effects of loxiglumide. ( Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Höcker, M; Nitsche, R; Nustede, R; Rovati, LC; Schleser, A; Schmidt, WE; Sostmann, H, 1991) |
| "Thus loxiglumide acts as a specific antagonist of the actions of CCK on small intestinal motor activity in the dog." | 1.28 | Effects of CCK receptor blockade on intestinal motor activity in conscious dogs. ( Karaus, M; Niederau, C, 1991) |
| "5 uM) caused a rightward shift of the dose-response curves of CCK-OP, with an increase of the ED50 from 8." | 1.28 | The effect of a novel CCK-antagonist (lorglumide) on human and guinea pig gallbladder strips: a tensiometric study. ( Brandonisio, R; Chiloiro, M; Di Ciaula, A; Maggi, V; Palasciano, G; Portincasa, P, 1990) |
| " The model was used to demonstrate a dose-response curve to bolus administration of exogenous cholecystokinin (0." | 1.28 | In vivo comparison of inhibition with proglumide and CR-1409 of cholecystokinin-induced pressure in the biliary tract of the guinea pig. ( Hashimoto, T; MacLellan, DG; Poston, GJ; Thompson, JC; Townsend, CM; Upp, JR, 1990) |
| "h of loxiglumide was able to prevent any postprandial emptying of the gallbladder." | 1.28 | Effect of loxiglumide on gallbladder contractile response to cerulein and food in humans. ( Bonato, C; De Fazio, C; Festorazzi, S; Malesci, A; Rovati, L; Setnikar, I; Tacconi, M; Valentini, A, 1990) |
| "Pretreatment with lorglumide caused a dose-dependent rightward shift of the dose-response curve, indicating competitive antagonism." | 1.28 | Cholecystokinin causes contraction of the pupillary sphincter in monkeys but not in cats, rabbits, rats and guinea-pigs: antagonism by lorglumide. ( Almegård, B; Andersson, SE; Bill, A, 1990) |
| " Close correlation between the decrease in gall bladder volume and the dosage of CCK or the increments in plasma CCK-bioactivity was observed." | 1.28 | CCK receptor antagonism by loxiglumide and gall bladder contractions in response to cholecystokinin, sham feeding and ordinary feeding in man. ( Bogdal, J; Konturek, JW; Konturek, SJ; Kurek, A; Oleksy, J; Rovati, L, 1989) |
| " Proglumide shifted the dose-response curves of the inhibitory as well as excitatory effects of CCK analogues to the right." | 1.27 | Structure-activity relationship of subtypes of cholecystokinin receptors in the cat lower esophageal sphincter. ( Goyal, RK; Rattan, S, 1986) |
| " The compounds are competitive and specific CCK-antagonists, causing a parallel right shift of the cumulative dose-response curve of the agonist." | 1.27 | New glutaramic acid derivatives with potent competitive and specific cholecystokinin-antagonistic activity. ( Bani, M; Chistè, R; Makovec, F; Pacini, MA; Rovati, LA; Setnikar, I, 1985) |
| " Inhibition by proglumide was competitive and resulted in a parallel rightward shift of the cholecystokinin dose-response curve." | 1.26 | Cholecystokinin-induced contraction of dispersed smooth muscle cells. ( Collins, SM; Gardner, JD, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (38.60) | 18.7374 |
| 1990's | 27 (47.37) | 18.2507 |
| 2000's | 7 (12.28) | 29.6817 |
| 2010's | 1 (1.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Makovec, F | 3 |
| Bani, M | 2 |
| Cereda, R | 1 |
| Chisté, R | 2 |
| Pacini, MA | 2 |
| Revel, L | 1 |
| Rovati, LA | 2 |
| Rovati, LC | 5 |
| Setnikar, I | 4 |
| Romański, KW | 1 |
| Onaga, T | 2 |
| Sugita, A | 1 |
| Wakaiki, R | 1 |
| Hara, I | 1 |
| Kagawa, K | 1 |
| Kirisawa, R | 1 |
| Hayashi, H | 1 |
| Lv, Y | 1 |
| Feng, M | 1 |
| Che, T | 1 |
| Sun, H | 1 |
| Luo, Y | 1 |
| Liu, K | 1 |
| Liu, C | 1 |
| Latorre, M | 1 |
| Bartolomé-Nebreda, JM | 1 |
| García-López, MT | 1 |
| González-Muñiz, R | 1 |
| Herranz, R | 1 |
| Del Río, J | 1 |
| Cenarruzabeitia, E | 1 |
| Liu, JF | 1 |
| Gao, LP | 1 |
| Wen, SW | 1 |
| Lu, HL | 1 |
| Zhang, J | 1 |
| Sun, J | 1 |
| Zhang, SW | 1 |
| Wang, QZ | 1 |
| Collins, SM | 2 |
| Gardner, JD | 2 |
| Kaplita, PV | 1 |
| Roebuck, BD | 1 |
| D'Amato, M | 3 |
| Kishimoto, S | 2 |
| Machino, H | 1 |
| Kobayashi, H | 1 |
| Haruma, K | 1 |
| Kajiyama, G | 1 |
| Miyoshi, A | 2 |
| Fujii, K | 2 |
| Wang, SX | 1 |
| Rakovska, A | 3 |
| Sgaragli, G | 1 |
| Mantovani, P | 3 |
| Valoti, M | 2 |
| Milenov, K | 2 |
| De Giorgio, R | 1 |
| Stanghellini, V | 1 |
| Ricci Maccarini, M | 1 |
| Morselli-Labate, AM | 1 |
| Barbara, G | 1 |
| Franzoso, L | 1 |
| Corinaldesi, R | 1 |
| Barbara, L | 1 |
| Go, VL | 1 |
| Brotschi, EA | 1 |
| Vaules, WA | 1 |
| Kahl, EA | 1 |
| Midis, NA | 1 |
| Hilbinger, CL | 1 |
| Taniguchi, H | 1 |
| Yazaki, N | 1 |
| Endo, T | 1 |
| Nagasaki, M | 1 |
| Rakowska, A | 1 |
| Adorni Ugolotti, MC | 1 |
| Liu, F | 1 |
| Naruse, S | 1 |
| Ozaki, T | 1 |
| Sazi, T | 1 |
| Kondo, T | 1 |
| Toda, Y | 1 |
| Parkman, HP | 1 |
| Pagano, AP | 1 |
| Ryan, JP | 1 |
| Hayashi, K | 1 |
| Kannbe, M | 1 |
| Clavé, P | 1 |
| González, A | 1 |
| Moreno, A | 1 |
| López, R | 1 |
| Farré, A | 1 |
| Cussó, X | 1 |
| Azpiroz, F | 1 |
| Lluís, F | 2 |
| Sterczer, A | 1 |
| Szénási, G | 1 |
| Vörös, K | 1 |
| Pap, A | 1 |
| Maselli, MA | 1 |
| Piepoli, AL | 1 |
| Pezzolla, F | 1 |
| Guerra, V | 1 |
| Caruso, ML | 1 |
| Mennuni, L | 1 |
| Lorusso, D | 1 |
| Harada, N | 1 |
| Chijiiwa, Y | 1 |
| Misawa, T | 1 |
| Yoshinaga, M | 1 |
| Nawata, H | 1 |
| Botella, A | 1 |
| Delvaux, M | 1 |
| Berry, P | 1 |
| Frexinos, J | 1 |
| Bueno, L | 1 |
| Almegård, B | 2 |
| Stjernschantz, J | 1 |
| Bill, A | 2 |
| Petkov, VV | 1 |
| De Castiglione, R | 1 |
| Schmidt, WE | 2 |
| Creutzfeldt, W | 2 |
| Schleser, A | 2 |
| Choudhury, AR | 2 |
| Nustede, R | 2 |
| Höcker, M | 2 |
| Nitsche, R | 2 |
| Sostmann, H | 1 |
| Fölsch, UR | 2 |
| Niederau, C | 1 |
| Karaus, M | 1 |
| Stamford, IF | 1 |
| Bennett, A | 1 |
| Portincasa, P | 1 |
| Brandonisio, R | 1 |
| Di Ciaula, A | 1 |
| Maggi, V | 1 |
| Chiloiro, M | 1 |
| Palasciano, G | 1 |
| Schafmayer, A | 1 |
| Corazziari, E | 1 |
| Ricci, R | 1 |
| Biliotti, D | 1 |
| Bontempo, I | 1 |
| De Medici, A | 1 |
| Pallotta, N | 1 |
| Torsoli, A | 1 |
| Poston, GJ | 1 |
| MacLellan, DG | 1 |
| Hashimoto, T | 1 |
| Upp, JR | 1 |
| Townsend, CM | 2 |
| Thompson, JC | 2 |
| Malesci, A | 1 |
| De Fazio, C | 1 |
| Festorazzi, S | 1 |
| Bonato, C | 1 |
| Valentini, A | 1 |
| Tacconi, M | 1 |
| Rovati, L | 2 |
| Baba, H | 1 |
| Fujimura, M | 2 |
| Toda, N | 1 |
| Andersson, SE | 1 |
| Severi, C | 1 |
| Grider, JR | 2 |
| Makhlouf, GM | 3 |
| Menozzi, D | 1 |
| Jensen, RT | 1 |
| Maton, PN | 1 |
| Moummi, C | 1 |
| Magous, R | 2 |
| Bali, JP | 2 |
| Kishimoto, M | 1 |
| Mitsukawa, T | 1 |
| Takemura, J | 1 |
| Nishizono, F | 1 |
| Nakatsuru, K | 1 |
| Ohgo, S | 1 |
| Matsukura, S | 1 |
| Ammor, S | 1 |
| Mingard, P | 1 |
| Combépine, G | 1 |
| Konturek, JW | 1 |
| Konturek, SJ | 1 |
| Kurek, A | 1 |
| Bogdal, J | 1 |
| Oleksy, J | 1 |
| Douglas, BR | 1 |
| Jebbink, MC | 1 |
| Tjon a Tham, RT | 1 |
| Jansen, JB | 1 |
| Lamers, CB | 1 |
| Bitar, KN | 1 |
| Harada, T | 1 |
| Katsuragi, T | 1 |
| Furukawa, T | 1 |
| Barone, FC | 1 |
| Bondinell, WE | 1 |
| Labosh, TJ | 1 |
| White, RF | 1 |
| Ormsbee, HS | 1 |
| Rattan, S | 1 |
| Goyal, RK | 1 |
| Rezvani, A | 1 |
| Stokes, KB | 1 |
| Rhoads, DL | 1 |
| Way, EL | 1 |
| Lonovics, J | 1 |
| Guo, YS | 1 |
| Gomez, G | 1 |
| Greeley, GH | 1 |
| Barthó, L | 1 |
| Holzer, P | 1 |
| Lembeck, F | 1 |
| Lippe, IT | 1 |
| Suzuki, T | 1 |
| Nakaya, M | 1 |
| Nakamura, T | 1 |
| Itoh, Z | 1 |
2 trials available for proglumide and Muscle Contraction
| Article | Year |
|---|---|
Cholecystokinin receptor antagonist loxiglumide: influence on bilio-pancreatic secretion and gastrointestinal hormones in man.
Topics: Adult; Cholecystokinin; Gallbladder; Humans; Male; Muscle Contraction; Muscle, Smooth; Pancreas; Pro | 1990 |
Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying.
Topics: Administration, Oral; Adult; Cholecystokinin; Double-Blind Method; Female; Food; Gallbladder; Gastri | 1990 |
55 other studies available for proglumide and Muscle Contraction
| Article | Year |
|---|---|
Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists.
Topics: Animals; Cholecystokinin; Dogs; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Mic | 1987 |
The effect of cholecystokinin peptides on ovine duodeno-jejunal slow waves with and without pretreatment with proglumide.
Topics: Animals; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Duodenum; Gastrointestinal A | 2007 |
Localization of CCK-1R in the omasum and role of CCK in the regulation of omasal contractions in sheep.
Topics: Animals; Atropine; Electromyography; Hormone Antagonists; In Vitro Techniques; Indoles; Meglumine; M | 2008 |
CCK mediated the inhibitory effect of oxytocin on the contraction of longitudinal muscle strips of duodenum in male rats.
Topics: Animals; Cholecystokinin; Duodenum; Gastrointestinal Motility; Male; Muscle Contraction; Myenteric P | 2010 |
Pharmacological study of IQM-97,423, a potent and selective CCK1 receptor antagonist with protective effect in experimental acute pancreatitis.
Topics: Acute Disease; alpha-Amylases; Animals; Binding, Competitive; Cerebral Cortex; Cholecystokinin; Deva | 2004 |
Effect of intravenous infusion of proglumide on ruminal motility in conscious sheep (Ovis aries).
Topics: Abomasum; Animals; Cholecystokinin; Duodenum; Gastrointestinal Motility; In Vitro Techniques; Infusi | 2007 |
Responses of human sling and clasp fibers to cholecystokinin (CCK) and gastrin through CCK receptors.
Topics: Adult; Benzodiazepines; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Esophagectomy | 2008 |
Cholecystokinin-induced contraction of dispersed smooth muscle cells.
Topics: Animals; Appetite Depressants; Biological Transport, Active; Calcimycin; Carbachol; Cholecystokinin; | 1982 |
Proglumide antagonizes the stimulation of rabbit gallbladder by cholecystokinin.
Topics: Acetylcholine; Animals; Cholecystokinin; Female; Gallbladder; Glutamine; In Vitro Techniques; Muscle | 1984 |
CCK-A antagonists: which and how.
Topics: Benzodiazepinones; Devazepide; Gallbladder; Humans; Muscle Contraction; Muscle, Smooth; Proglumide; | 1995 |
Inhibitory action of CCK-OP on rat proximal colon.
Topics: Acetylcholine; Animals; Atropine; Colon; Fasting; Hexamethonium; Hexamethonium Compounds; Muscle Con | 1994 |
[Effect of cholecystokinin and its antagonists lorglumide, devazepide, and L-365,260 on gastrointestinal motility in rats].
Topics: Animals; Benzodiazepinones; Devazepide; Gastric Emptying; Gastrointestinal Motility; Guinea Pigs; Il | 1993 |
Effect of loxiglumide (CR 1505) on CCK-induced contractions and 3H-acetylcholine release from guinea-pig gallbladder.
Topics: Acetylcholine; Animals; Cholecystokinin; Female; Gallbladder; Guinea Pigs; In Vitro Techniques; Male | 1993 |
Effects of dietary fat on postprandial gastrointestinal motility are inhibited by a cholecystokinin type A receptor antagonist.
Topics: Adult; Corn Oil; Dietary Fats; Duodenum; Eating; Female; Gastrointestinal Motility; Humans; Infusion | 1994 |
Neuronal receptors for caerulein in gallbladder.
Topics: Acetylcholine; Animals; Ceruletide; Gallbladder; Guinea Pigs; Muscle Contraction; Neurons; Proglumid | 1993 |
Luminal cholecystokinin and gastrin cause gallbladder contraction.
Topics: Animals; Bile; Cholecystokinin; Female; Gallbladder; Gastrins; Guinea Pigs; Hormone Antagonists; In | 1996 |
Pharmacological profile of T-0632, a novel potent and selective CCKA receptor antagonist, in vitro.
Topics: Amylases; Animals; Benzodiazepinones; Binding, Competitive; Brain; Cell Membrane; Devazepide; Gallbl | 1996 |
Ca2+ antagonists reveal a novel inhibitory effect of caerulein on guinea pig ileum.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Ceruletide; Dibutyryl Cyclic GMP; Electric Stimula | 1995 |
Effect of gastrin-releasing peptide (GRP) on guinea pig gallbladder contraction in vitro.
Topics: Acetylcholine; Animals; Atropine; Bombesin; Dose-Response Relationship, Drug; Gallbladder; Gastrin-R | 1995 |
Dual effects of PACAP on guinea pig gallbladder muscle via PACAP-preferring and VIP/PACAP-preferring receptors.
Topics: Animals; Atropine; Cholecystokinin; Gallbladder; Guinea Pigs; In Vitro Techniques; Kinetics; Muscle | 1997 |
Endogenous CCK inhibits colonic contractions in unrestrained conscious rats.
Topics: Animal Feed; Animals; Colon; Dose-Response Relationship, Drug; Duodenum; Eating; Fasting; Gastrointe | 1997 |
Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors.
Topics: Adult; Cholecystokinin; Cholestyramine Resin; Eating; Electric Stimulation; Esophagogastric Junction | 1998 |
Effects of lorglumide and atropine on MgSO(4)-induced gallbladder emptying in conscious dogs.
Topics: Animals; Atropine; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Femal | 2000 |
Effect of three nonpeptide cholecystokinin antagonists on human isolated gallbladder.
Topics: Cholecystokinin; Gallbladder; Hormone Antagonists; Humans; In Vitro Techniques; Muscle Contraction; | 2001 |
Direct contractile effect of motilin on isolated smooth muscle cells of guinea pig small intestine.
Topics: Animals; Atropine; Calcium; Cholecystokinin; Guinea Pigs; In Vitro Techniques; Intestine, Small; Mal | 1992 |
Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes.
Topics: Animals; Calcium; Cholecystokinin; Dose-Response Relationship, Drug; Gastrins; Ileum; In Vitro Techn | 1992 |
Cholecystokinin contracts isolated human and monkey iris sphincters; a study with CCK receptor antagonists.
Topics: Aged; Aged, 80 and over; Animals; Cholecystokinin; Female; Humans; In Vitro Techniques; Iris; Macaca | 1992 |
Caerulein receptors on the cholinergic neurons in guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniq | 1991 |
Role of CCK in regulation of pancreaticobiliary functions and GI motility in humans: effects of loxiglumide.
Topics: Adult; Bilirubin; Cholecystokinin; Eating; Feces; Gallbladder; Gastrointestinal Motility; Humans; Li | 1991 |
Effects of CCK receptor blockade on intestinal motor activity in conscious dogs.
Topics: Animals; Ceruletide; Cholecystokinin; Digestion; Dogs; Eating; Female; Gastrointestinal Motility; Ma | 1991 |
Studies of three non-peptide cholecystokinin antagonists (devazepide, lorglumide and loxiglumide) in human isolated alimentary muscle and guinea-pig ileum.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Digestive System; Digestive System Physiolo | 1991 |
The effect of a novel CCK-antagonist (lorglumide) on human and guinea pig gallbladder strips: a tensiometric study.
Topics: Adult; Aged; Animals; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs; Humans; Male; Midd | 1990 |
In vivo comparison of inhibition with proglumide and CR-1409 of cholecystokinin-induced pressure in the biliary tract of the guinea pig.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gallbladder; Glutamine; Guinea Pigs; Mal | 1990 |
Effect of loxiglumide on gallbladder contractile response to cerulein and food in humans.
Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Feeding Beh | 1990 |
Mechanism of inhibitory action of peptide YY on cholecystokinin-induced contractions of isolated dog ileum.
Topics: Animals; Cholecystokinin; Dogs; Female; Gallbladder; Glutamine; Ileum; Isometric Contraction; Male; | 1990 |
Cholecystokinin causes contraction of the pupillary sphincter in monkeys but not in cats, rabbits, rats and guinea-pigs: antagonism by lorglumide.
Topics: Animals; Cats; Cholecystokinin; Eye; Female; Guinea Pigs; Indomethacin; Macaca; Macaca fascicularis; | 1990 |
Calcium utilization by dispersed canine gastric smooth muscle cells.
Topics: Animals; Calcium; Carbachol; Dogs; Egtazic Acid; Female; Gastric Mucosa; Ion Channels; Male; Muscle | 1986 |
Identification of separate bombesin and substance P receptors on isolated muscle cells from canine gallbladder.
Topics: Animals; Atropine; Bombesin; Dogs; Gallbladder; Muscle Contraction; Muscles; Naloxone; Peptide Fragm | 1988 |
Properties of receptors for gastrin and CCK on gastric smooth muscle cells.
Topics: Amylases; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Gastrins; Guinea Pigs; Male; Musc | 1989 |
Gastrointestinal hormone receptors on isolated smooth muscle cells from gastric antrum of the rabbit.
Topics: Animals; Calcium; Cholecystokinin; Gastrins; In Vitro Techniques; Motilin; Muscle Contraction; Muscl | 1989 |
[Effect of CCK on the large intestine].
Topics: Animals; Cholecystokinin; Gastrointestinal Motility; Glutamine; Intestine, Large; Male; Muscle Contr | 1989 |
Effects of atropine, proglumide, and somatostatin analogue (SMS 201-995) on bombesin-induced gallbladder contraction and CCK secretion in humans.
Topics: Adult; Atropine; Bombesin; Cholecystokinin; Gallbladder; Glutamine; Humans; Male; Muscle Contraction | 1989 |
[Effects of anti-tissue immune sera on the contractile response of cells isolated from smooth muscle of the pyloric antrum].
Topics: Animals; Colon; Diencephalon; Dose-Response Relationship, Drug; Immune Sera; Muscle Contraction; Mus | 1989 |
CCK receptor antagonism by loxiglumide and gall bladder contractions in response to cholecystokinin, sham feeding and ordinary feeding in man.
Topics: Adolescent; Adult; Cholecystokinin; Food; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; | 1989 |
The effect of loxiglumide (CR-1505) on basal and bombesin-stimulated gallbladder volume in man.
Topics: Adult; Bombesin; Cholecystokinin; Female; Gallbladder; Humans; Male; Muscle Contraction; Muscle, Smo | 1989 |
Selective presence of opiate receptors on intestinal circular muscle cells.
Topics: Acetylcholine; Animals; Atropine; Benzomorphans; beta-Endorphin; Dose-Response Relationship, Drug; D | 1985 |
Release of acetylcholine mediated by cholecystokinin receptor from the guinea pig sphincter of Oddi.
Topics: Acetylcholine; Ampulla of Vater; Angiotensin II; Animals; Atropine; Bethanechol; Bethanechol Compoun | 1986 |
Cholecystokinin stimulates neuronal receptors to produce contraction of the canine colon.
Topics: Acetylcholine; Animals; Atropine; Cholecystokinin; Colon; Dibutyryl Cyclic GMP; Dogs; Dose-Response | 1989 |
Structure-activity relationship of subtypes of cholecystokinin receptors in the cat lower esophageal sphincter.
Topics: Animals; Cats; Cholecystokinin; Dose-Response Relationship, Drug; Esophagogastric Junction; Female; | 1986 |
Proglumide exhibits delta opioid agonist properties.
Topics: Animals; Binding, Competitive; Electric Stimulation; Enkephalin, Leucine; Enzyme Inhibitors; Glutami | 1987 |
Peptide YY and gallbladder contraction. Studies in vivo and in vitro.
Topics: Ampulla of Vater; Animals; Dogs; Female; Gallbladder; Gastrointestinal Hormones; In Vitro Techniques | 1988 |
Evaluation of a new and potent cholecystokinin antagonist on motor responses of the guinea-pig intestine.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Glutamine; | 1987 |
Regional and cellular heterogeneity of cholecystokinin receptors mediating muscle contraction in the gut.
Topics: Animals; Gallbladder; Gastric Fundus; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; | 1987 |
[Effect of proglumide on gastrointestinal motility and gastric secretion in the conscious state].
Topics: Animals; Dogs; Gastric Acid; Gastrointestinal Motility; Glutamine; Muscle Contraction; Pentagastrin; | 1985 |
New glutaramic acid derivatives with potent competitive and specific cholecystokinin-antagonistic activity.
Topics: Acetylcholine; Animals; Cholecystokinin; Gallbladder; Guinea Pigs; Histamine; In Vitro Techniques; I | 1985 |