proglumide has been researched along with Morphine Abuse in 2 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Proglumide both shifted the dose-response curve for morphine analgesia to the left and prolonged morphine's duration of action." | 1.28 | Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice. ( Bodnar, RJ; Pasternak, GW; Paul, D, 1990) |
| " Proglumide and benzotript were able to inhibit the shift to the right of the dose-response curve for morphine, i." | 1.27 | Dissociation of tolerance and dependence to morphine: a possible role for cholecystokinin. ( Cocco, E; Mantegazza, P; Panerai, AE; Rovati, LC; Sacerdote, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodnar, RJ | 1 |
| Paul, D | 1 |
| Pasternak, GW | 1 |
| Panerai, AE | 1 |
| Rovati, LC | 1 |
| Cocco, E | 1 |
| Sacerdote, P | 1 |
| Mantegazza, P | 1 |
2 other studies available for proglumide and Morphine Abuse
| Article | Year |
|---|---|
Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penici | 1990 |
Dissociation of tolerance and dependence to morphine: a possible role for cholecystokinin.
Topics: Animals; Benzamides; Central Nervous System; Cholecystokinin; Drug Interactions; Drug Tolerance; Mal | 1987 |