proglumide has been researched along with Local Neoplasm Recurrence in 3 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist." | 9.06 | A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990) |
| "Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist." | 5.06 | A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990) |
| " Clinical symptoms and physical signs, laboratory tests, and adverse reactions were checked every 6 weeks as efficacy/tolerability criteria." | 2.68 | Clinical evaluation and safety of loxiglumide (CCK-A receptor antagonist) in nonresectable pancreatic cancer patients. Italian Pancreatic Cancer Study Group. ( Di Prima, F; Militello, C; Pedrazzoli, S; Sperti, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kameyama, M | 1 |
| Nakamori, S | 1 |
| Imaoka, S | 1 |
| Yasuda, T | 1 |
| Nakano, H | 1 |
| Ohigashi, H | 1 |
| Hiratsuka, M | 1 |
| Sasaki, Y | 1 |
| Kabuto, T | 1 |
| Ishikawa, O | 1 |
| Militello, C | 1 |
| Sperti, C | 1 |
| Di Prima, F | 1 |
| Pedrazzoli, S | 1 |
| Morris, DL | 1 |
| Charnley, RM | 1 |
| Ballantyne, KC | 1 |
| Jones, J | 1 |
3 trials available for proglumide and Local Neoplasm Recurrence
| Article | Year |
|---|---|
[Adjuvant chemo-endocrine chemotherapy with gastrin antagonist after resection of liver metastasis in colorectal cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj | 1994 |
Clinical evaluation and safety of loxiglumide (CCK-A receptor antagonist) in nonresectable pancreatic cancer patients. Italian Pancreatic Cancer Study Group.
Topics: Double-Blind Method; Female; Hormone Antagonists; Humans; Male; Middle Aged; Neoplasm Recurrence, Lo | 1997 |
A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer.
Topics: Adenocarcinoma; Carcinoembryonic Antigen; Colorectal Neoplasms; Humans; Liver Neoplasms; Neoplasm Re | 1990 |