proglumide has been researched along with Hyperplasia in 4 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Long-term treatment with omeprazole induces hyperplasia of enterochromaffin-like cells, closely related to hypergastrinemia." | 7.68 | Effects of proglumide and enprostil on omeprazole-induced fundic endocrine cell hyperplasia in rats. ( Belaïche, J; Delwaide, J; Gast, P; Latour, P; Louis, E, 1993) |
| "Long-term treatment with omeprazole induces hyperplasia of enterochromaffin-like cells, closely related to hypergastrinemia." | 3.68 | Effects of proglumide and enprostil on omeprazole-induced fundic endocrine cell hyperplasia in rats. ( Belaïche, J; Delwaide, J; Gast, P; Latour, P; Louis, E, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsyriuk, OI | 1 |
| Delwaide, J | 1 |
| Latour, P | 1 |
| Gast, P | 1 |
| Louis, E | 1 |
| Belaïche, J | 1 |
| Rodríguez-Martín, E | 1 |
| Valencia, AM | 1 |
| Colás, B | 1 |
| García-Escribano, C | 1 |
| Rodríguez-Puyol, M | 1 |
| Susini, C | 1 |
| Arilla, E | 1 |
| Upp, JR | 1 |
| Poston, GJ | 1 |
| MacLellan, DG | 1 |
| Townsend, CM | 1 |
| Barranco, SC | 1 |
| Thompson, JC | 1 |
4 other studies available for proglumide and Hyperplasia
| Article | Year |
|---|---|
[Correction of negative influence of long-term hypergastrinemia on gastric acid secretion].
Topics: Animals; Anti-Ulcer Agents; Drug Therapy, Combination; Gastric Acid; Gastric Mucosa; Gastrins; Hyper | 2011 |
Effects of proglumide and enprostil on omeprazole-induced fundic endocrine cell hyperplasia in rats.
Topics: Animals; Cell Count; Depression, Chemical; Drug Combinations; Enprostil; Enterochromaffin Cells; Fem | 1993 |
Somatostatin binding capacity, guanylate cyclase and tyrosine phosphatase activities during pancreatic proliferation in the rat induced by gastrectomy.
Topics: Animals; Gastrectomy; Guanylate Cyclase; Hyperplasia; Male; Pancreas; Proglumide; Protein Tyrosine P | 1995 |
Mechanisms of the trophic actions of bombesin on the pancreas.
Topics: Animals; Bombesin; Cholecystokinin; DNA; Hyperplasia; Pancreas; Polyamines; Proglumide; Proteins; Pu | 1988 |