proglumide has been researched along with Helicobacter Infections in 4 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exogenous cholecystokinin (CCK) is known to effect gastric secretory and motor functions but its physiological role in the control of these functions in healthy subjects and duodenal ulcer (DU) patients is unknown." | 10.17 | Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori. ( Konturek, JW, 1994) |
| "Increased gastric emptying and defective action of endogenous cholecystokinin (CCK), that is known to inhibit this emptying, have been implicated in the pathogenesis of duodenal ulcer (DU)." | 9.09 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients. ( Domschke, W; Konturek, JW; Konturek, M; Konturek, SJ; Menzel, J; Stoll, R, 2001) |
| "Cholecystokinin (CCK) has been implicated in the feedback control of gastric acid secretion in healthy subjects but its contribution to secretory disorders in DU patients has been little examined." | 6.68 | Eradication of Helicobacter pylori and gastrin-somatostatin link in duodenal ulcer patients. ( Bielański, W; Domschke, W; Konturek, JW; Konturek, SJ, 1996) |
| "Exogenous cholecystokinin (CCK) is known to effect gastric secretory and motor functions but its physiological role in the control of these functions in healthy subjects and duodenal ulcer (DU) patients is unknown." | 6.17 | Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori. ( Konturek, JW, 1994) |
| "Cholecystokinin (CCK) has been implicated in the feedback control of gastrin release and gastric acid secretion in healthy subjects." | 5.29 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on postprandial gastrin release in duodenal ulcer patients. ( Domschke, W; Gillessen, A; Konturek, JW; Konturek, SJ, 1995) |
| "Increased gastric emptying and defective action of endogenous cholecystokinin (CCK), that is known to inhibit this emptying, have been implicated in the pathogenesis of duodenal ulcer (DU)." | 5.09 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients. ( Domschke, W; Konturek, JW; Konturek, M; Konturek, SJ; Menzel, J; Stoll, R, 2001) |
| "Cholecystokinin (CCK) has been implicated in the feedback control of gastric acid secretion in healthy subjects but its contribution to secretory disorders in DU patients has been little examined." | 2.68 | Eradication of Helicobacter pylori and gastrin-somatostatin link in duodenal ulcer patients. ( Bielański, W; Domschke, W; Konturek, JW; Konturek, SJ, 1996) |
| "Cholecystokinin (CCK) has been implicated in the feedback control of gastrin release and gastric acid secretion in healthy subjects." | 1.29 | Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on postprandial gastrin release in duodenal ulcer patients. ( Domschke, W; Gillessen, A; Konturek, JW; Konturek, SJ, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Konturek, JW | 4 |
| Gillessen, A | 1 |
| Konturek, SJ | 3 |
| Domschke, W | 3 |
| Bielański, W | 1 |
| Stoll, R | 1 |
| Menzel, J | 1 |
| Konturek, M | 1 |
1 review available for proglumide and Helicobacter Infections
| Article | Year |
|---|---|
Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.
Topics: Adult; Anti-Bacterial Agents; Cholecystokinin; Dietary Fats; Duodenal Ulcer; Eating; Gastric Acid; G | 1994 |
3 trials available for proglumide and Helicobacter Infections
| Article | Year |
|---|---|
Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.
Topics: Adult; Anti-Bacterial Agents; Cholecystokinin; Dietary Fats; Duodenal Ulcer; Eating; Gastric Acid; G | 1994 |
Eradication of Helicobacter pylori and gastrin-somatostatin link in duodenal ulcer patients.
Topics: Adult; Cholecystokinin; Duodenal Ulcer; Gastric Acid; Gastric Mucosa; Gastrins; Helicobacter Infecti | 1996 |
Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on gastric motility in duodenal ulcer patients.
Topics: Adolescent; Adult; Analysis of Variance; Cholecystokinin; Duodenal Ulcer; Follow-Up Studies; Gastric | 2001 |
1 other study available for proglumide and Helicobacter Infections
| Article | Year |
|---|---|
Eradication of Helicobacter pylori restores the inhibitory effect of cholecystokinin on postprandial gastrin release in duodenal ulcer patients.
Topics: Adult; Cholecystokinin; Duodenal Ulcer; Eating; Gastric Acid; Gastrins; Helicobacter Infections; Hel | 1995 |