proglumide has been researched along with Esophageal Reflux in 7 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 5.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| "Endogenous CCK enhances postprandial gastroesophageal reflux in humans by increasing the rate of TLESRs and reduces postprandial LES pressure." | 1.30 | Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. ( Azpiroz, F; Clavé, P; Cussó, X; D'Amato, M; Farré, A; González, A; Lluís, F; López, R; Moreno, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buéno, L | 1 |
| Hondé, C | 1 |
| Fioramonti, J | 1 |
| Boulant, J | 1 |
| Mathieu, S | 1 |
| D'Amato, M | 4 |
| Abergel, A | 1 |
| Dapoigny, M | 1 |
| Bommelaer, G | 1 |
| Clavé, P | 1 |
| González, A | 1 |
| Moreno, A | 1 |
| López, R | 1 |
| Farré, A | 1 |
| Cussó, X | 1 |
| Azpiroz, F | 1 |
| Lluís, F | 1 |
| Boeckxstaens, GE | 2 |
| Hirsch, DP | 2 |
| Fakhry, N | 1 |
| Holloway, RH | 1 |
| Tytgat, GN | 2 |
| Trudgill, NJ | 1 |
| Hussain, FN | 1 |
| Moustafa, M | 1 |
| Ajjan, R | 1 |
| Riley, SA | 1 |
| McCallum, RW | 1 |
1 review available for proglumide and Esophageal Reflux
| Article | Year |
|---|---|
Transient lower oesophageal sphincter relaxations--a pharmacological target for gastro-oesophageal reflux disease?
Topics: Atropine; Baclofen; Endoscopy, Gastrointestinal; Esophagogastric Junction; Fundoplication; GABA Agon | 2002 |
3 trials available for proglumide and Esophageal Reflux
| Article | Year |
|---|---|
Cholecystokinin in transient lower oesophageal sphincter relaxation due to gastric distension in humans.
Topics: Adult; Cholecystokinin; Double-Blind Method; Esophagogastric Junction; Female; Gastroesophageal Refl | 1997 |
Involvement of cholecystokininA receptors in transient lower esophageal sphincter relaxations triggered by gastric distension.
Topics: Adult; Deglutition; Double-Blind Method; Esophagogastric Junction; Female; Gastroesophageal Reflux; | 1998 |
The effect of cholecystokinin antagonism on postprandial lower oesophageal sphincter function in asymptomatic volunteers and patients with reflux disease.
Topics: Adult; Aged; Cholecystokinin; Cross-Over Studies; Double-Blind Method; Esophagogastric Junction; Fem | 2001 |
3 other studies available for proglumide and Esophageal Reflux
| Article | Year |
|---|---|
Proglumide: selective antagonism of the rumination but not gastric motor effects induced by pentagastrin in sheep.
Topics: Abomasum; Animals; Electromyography; Female; Gastroesophageal Reflux; Gastrointestinal Motility; Glu | 1984 |
Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors.
Topics: Adult; Cholecystokinin; Cholestyramine Resin; Eating; Electric Stimulation; Esophagogastric Junction | 1998 |
Review of the current status of prokinetic agents in gastroenterology.
Topics: Benzamides; Chemical Phenomena; Chemistry; Cisapride; Dexamethasone; Digestive System; Domperidone; | 1985 |