Page last updated: 2024-11-03

proglumide and Dyspepsia

proglumide has been researched along with Dyspepsia in 3 studies

Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"Cholecystokinin (CCK) is an established brain-gut peptide that plays an important regulatory role in gastrointestinal function."6.43Cholecystokinin hyperresponsiveness in functional dyspepsia. ( Chua, AS; Keeling, PW, 2006)
"Cholecystokinin (CCK) is an established brain-gut peptide that plays an important regulatory role in gastrointestinal function."2.43Cholecystokinin hyperresponsiveness in functional dyspepsia. ( Chua, AS; Keeling, PW, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chua, AS2
Keeling, PW2
Mazzone, O1
Monello, S1
Trovato, GM1
MandalĂ , ML1
Di Frazzio, S1
Bekkering, M1
Rovati, LC1

Reviews

1 review available for proglumide and Dyspepsia

ArticleYear
Cholecystokinin hyperresponsiveness in functional dyspepsia.
    World journal of gastroenterology, 2006, May-07, Volume: 12, Issue:17

    Topics: Atropine; Cholecystokinin; Dyspepsia; Efferent Pathways; Food Hypersensitivity; Gastrointestinal Mot

2006

Trials

1 trial available for proglumide and Dyspepsia

ArticleYear
Clinical efficacy and prokinetic effect of the CCK-A antagonist loxiglumide in nonulcer dyspepsia.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Adult; Analysis of Variance; Double-Blind Method; Dyspepsia; Female; Gastric Emptying; Humans; Male;

1994

Other Studies

1 other study available for proglumide and Dyspepsia

ArticleYear
[Effects of proglumide on gastric motility].
    La Clinica terapeutica, 1981, Jan-15, Volume: 96, Issue:1

    Topics: Adult; Aged; Dyspepsia; Female; Gastric Emptying; Gastric Juice; Gastrointestinal Motility; Glutamin

1981