Page last updated: 2024-11-03

proglumide and Colonic Diseases, Functional

proglumide has been researched along with Colonic Diseases, Functional in 4 studies

Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.

Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cann, PA1
Rovati, LC1
Smart, HL1
Spiller, RC1
Whorwell, PJ1
Scarpignato, C1
Pelosini, I1
Niederau, C1
Faber, S1
Karaus, M1
Chaussade, S1

Reviews

1 review available for proglumide and Colonic Diseases, Functional

ArticleYear
Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1999, Volume: 13 Suppl A

    Topics: Animals; Cisapride; Colonic Diseases, Functional; Erythromycin; Gastrointestinal Agents; Gastrointes

1999

Trials

2 trials available for proglumide and Colonic Diseases, Functional

ArticleYear
Loxiglumide, a CCK-A antagonist, in irritable bowel syndrome. A pilot multicenter clinical study.
    Annals of the New York Academy of Sciences, 1994, Mar-23, Volume: 713

    Topics: Administration, Oral; Colonic Diseases, Functional; Diarrhea; Dose-Response Relationship, Drug; Pilo

1994
Cholecystokinin's role in regulation of colonic motility in health and in irritable bowel syndrome.
    Gastroenterology, 1992, Volume: 102, Issue:6

    Topics: Adult; Ceruletide; Cholecystokinin; Colon; Colonic Diseases, Functional; Female; Gastrointestinal Mo

1992

Other Studies

1 other study available for proglumide and Colonic Diseases, Functional

ArticleYear
[Therapeutic perspectives in the irritable bowel syndrome].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:5 ( Pt 2)

    Topics: Abdominal Pain; Antidiarrheals; Benzodiazepines; Cholecystokinin; Colonic Diseases, Functional; Cons

1990