Page last updated: 2024-11-03

proglumide and Alloxan Diabetes

proglumide has been researched along with Alloxan Diabetes in 3 studies

Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.

Research Excerpts

ExcerptRelevanceReference
"Proglumide was ineffective by itself and it did not affect the antinociception induced by the cyclooxygenase inhibitors in non-diabetic rats."1.37Proglumide enhances the antinociceptive effect of cyclooxygenase inhibitors in diabetic rats in the formalin test. ( Aguilar-Mariscal, H; Bermúdez-Ocaña, DY; Blé-Castillo, JL; Díaz-Zagoya, JC; Flores-Murrieta, FJ; Frías, TR; Granados-Soto, V; Juárez-Rojop, IE, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bermúdez-Ocaña, DY1
Aguilar-Mariscal, H1
Frías, TR1
Blé-Castillo, JL1
Flores-Murrieta, FJ2
Díaz-Zagoya, JC2
Granados-Soto, V2
Juárez-Rojop, IE2
Torres-López, JE1
Ortíz-López, JU1
Cruz-Vera, J1
Parmar, NS1
Tariq, M1
Ageel, AM1

Other Studies

3 other studies available for proglumide and Alloxan Diabetes

ArticleYear
Proglumide enhances the antinociceptive effect of cyclooxygenase inhibitors in diabetic rats in the formalin test.
    European journal of pharmacology, 2011, Aug-16, Volume: 664, Issue:1-3

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclooxygenase Inhib

2011
Peripheral participation of cholecystokinin in the morphine-induced peripheral antinociceptive effect in non-diabetic and diabetic rats.
    Neuropharmacology, 2007, Volume: 52, Issue:3

    Topics: Animals; Area Under Curve; Cholecystokinin; Diabetes Mellitus, Experimental; Dose-Response Relations

2007
Proglumide, a cholecystokinin receptor antagonist, exacerbates alloxan-induced diabetes mellitus in Swiss mice.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:12

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glutamine; Insulin; Male; Mice; Proglumide;

1987