proglumide has been researched along with Allodynia in 4 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mechanical allodynia elicited by burn injury was partially reversed by meloxicam (5 mg/kg), gabapentin (100 mg/kg) and oxycodone (3 and 10 mg/kg), while thermal allodynia and gait abnormalities were only significantly improved by amitriptyline (3 mg/kg) and oxycodone (10 mg/kg)." | 3.83 | Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. ( Deuis, JR; Lewis, RJ; Vetter, I; Yin, K, 2016) |
| " Both nocebo hyperalgesia and HPA hyperactivity were antagonized by the benzodiazepine diazepam, suggesting that anxiety played a major role in these effects." | 3.73 | The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect. ( Amanzio, M; Asteggiano, G; Benedetti, F; Vighetti, S, 2006) |
| "In patients who reported mild postoperative pain, we evoked a nocebo response, a phenomenon equal but opposite to placebo." | 2.68 | Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide. ( Amanzio, M; Benedetti, F; Casadio, C; Maggi, G; Oliaro, A, 1997) |
| "Mustard oil hyperalgesia was also inhibited in animals that had received electrolytic lesions in the rostral ventromedial medulla (RVM)." | 1.29 | Participation of central descending nociceptive facilitatory systems in secondary hyperalgesia produced by mustard oil. ( Gebhart, GF; Jiang, MC; Urban, MO, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yin, K | 1 |
| Deuis, JR | 1 |
| Lewis, RJ | 1 |
| Vetter, I | 1 |
| Benedetti, F | 2 |
| Amanzio, M | 2 |
| Vighetti, S | 1 |
| Asteggiano, G | 1 |
| Urban, MO | 1 |
| Jiang, MC | 1 |
| Gebhart, GF | 1 |
| Casadio, C | 1 |
| Oliaro, A | 1 |
| Maggi, G | 1 |
1 trial available for proglumide and Allodynia
| Article | Year |
|---|---|
Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide.
Topics: Analgesics, Non-Narcotic; Cholecystokinin; Double-Blind Method; Female; Humans; Hyperalgesia; Male; | 1997 |
3 other studies available for proglumide and Allodynia
| Article | Year |
|---|---|
Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target.
Topics: Amines; Amitriptyline; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; Gai | 2016 |
The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Anxiety Agents; Anti-Ulcer Agents; Anxiety; Cholecystokinin | 2006 |
Participation of central descending nociceptive facilitatory systems in secondary hyperalgesia produced by mustard oil.
Topics: Animals; Anti-Ulcer Agents; Benzodiazepinones; Cholecystokinin; Denervation; Devazepide; Hormone Ant | 1996 |