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proglumide and Adenocarcinoma, Basal Cell

proglumide has been researched along with Adenocarcinoma, Basal Cell in 12 studies

Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.

Research Excerpts

ExcerptRelevanceReference
"We performed a randomized, controlled study of gastrin receptor antagonist proglumide in 301 patients with cardiac adenocarcinoma after proximal subtotal gastrectomy."9.11Long-term effects of proglumide on resection of cardiac adenocarcinoma. ( Chen, YP; Liu, DT; Yang, JS; Yang, WP, 2005)
"Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist."9.06A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990)
"Nude mice bearing SW-1990 pancreatic cancer xenografts were injected with CCK (5, 15, or 25 micrograms/kg) or vehicle twice daily for 20 days."5.28Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990. ( Bagheri, S; Kramer, S; Smith, JP; Solomon, TE, 1990)
"We performed a randomized, controlled study of gastrin receptor antagonist proglumide in 301 patients with cardiac adenocarcinoma after proximal subtotal gastrectomy."5.11Long-term effects of proglumide on resection of cardiac adenocarcinoma. ( Chen, YP; Liu, DT; Yang, JS; Yang, WP, 2005)
"Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist."5.06A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990)
" To evaluate the involvement of this hormone in the proliferation of gastric tumors, we studied the effects of gastrin/CCK-receptor antagonists (L365,260 and L364,718), proglumide and C terminal-specific gastrin antibodies on the human gastric adenocarcinoma cell line HGT-1."3.68Evidence for autocrine growth stimulation by a gastrin/CCK-like peptide of the gastric cancer HGT-1 cell line. ( Bali, JP; Chevillard, C; Laboisse, C; Laliberté, MF; Nonotte, I; Perrier-Meissonnier, S; Remy-Heintz, N, 1993)
"The effects of gastrin, proglumide (a gastrin receptor antagonist), and somatostatin on growth of human colon adenocarcinoma cell lines CX1, X56, and HT29 were examined in two experimental models."3.67Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer. ( Smith, JP; Solomon, TE, 1988)
"The incidence of pancreatic cancer appeared significantly (P < 0."1.29Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat. ( Alaggio, R; Behboo, R; Khajeturian, E; Militello, C; Pedrazzoli, S; Perasole, A; Rovati, L; Sperti, C, 1994)
"Nude mice bearing SW-1990 pancreatic cancer xenografts were injected with CCK (5, 15, or 25 micrograms/kg) or vehicle twice daily for 20 days."1.28Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990. ( Bagheri, S; Kramer, S; Smith, JP; Solomon, TE, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's7 (58.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mao, JD1
Wu, P1
Huang, JX1
Wu, J1
Yang, G1
Chen, YP1
Yang, JS1
Liu, DT1
Yang, WP1
Sperti, C1
Militello, C1
Rovati, L1
Behboo, R1
Khajeturian, E1
Perasole, A1
Alaggio, R1
Pedrazzoli, S1
Remy-Heintz, N1
Perrier-Meissonnier, S1
Nonotte, I1
Laliberté, MF1
Chevillard, C1
Laboisse, C1
Bali, JP1
Funakoshi, A1
Kono, A1
Yactayo, S1
Patrice, T1
Foultier, MT1
Berrada, A1
Xu, XN1
Morris, DL1
Charnley, RM1
Ballantyne, KC1
Jones, J1
Smith, JP2
Solomon, TE2
Bagheri, S1
Kramer, S1
Bershteĭn, LM1
Zabezhinskiĭ, MA1
Stukov, AN1
Kalikhevich, VN1
Mikheev, AM1
Schusdziarra, V1
Beauchamp, RD1
Townsend, CM1
Singh, P1
Glass, EJ1
Thompson, JC1

Trials

2 trials available for proglumide and Adenocarcinoma, Basal Cell

ArticleYear
Long-term effects of proglumide on resection of cardiac adenocarcinoma.
    World journal of gastroenterology, 2005, May-07, Volume: 11, Issue:17

    Topics: Adenocarcinoma; Anti-Ulcer Agents; Combined Modality Therapy; Female; Heart Neoplasms; Humans; Male;

2005
A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1990, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Carcinoembryonic Antigen; Colorectal Neoplasms; Humans; Liver Neoplasms; Neoplasm Re

1990

Other Studies

10 other studies available for proglumide and Adenocarcinoma, Basal Cell

ArticleYear
Role of ERK-MAPK signaling pathway in pentagastrin-regulated growth of large intestinal carcinoma.
    World journal of gastroenterology, 2014, Sep-21, Volume: 20, Issue:35

    Topics: Adenocarcinoma; Apoptosis; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug;

2014
Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat.
    Journal of surgical oncology, 1994, Volume: 57, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Ceruletide; Chi-Square Distr

1994
Evidence for autocrine growth stimulation by a gastrin/CCK-like peptide of the gastric cancer HGT-1 cell line.
    Molecular and cellular endocrinology, 1993, Volume: 93, Issue:1

    Topics: Adenocarcinoma; Antibodies; Benzodiazepinones; Cell Division; Devazepide; Gastrins; Growth Substance

1993
Growth inhibition of human pancreatic cancer cells by cholecystokinin receptor antagonist in tissue culture and in nude mice.
    Gastroenterologia Japonica, 1992, Volume: 27, Issue:1

    Topics: Adenocarcinoma; Animals; Ceruletide; Cholecystokinin; Humans; In Vitro Techniques; Liver Neoplasms;

1992
[Effect of gastrin and enprostil, a PGE2 analog, on colonic cancerous cell growth].
    Gastroenterologie clinique et biologique, 1991, Volume: 15, Issue:6-7

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Combinations; Enprostil; Gastri

1991
Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:11

    Topics: Adenocarcinoma; Animals; Cholecystokinin; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; M

1990
[The hormonal sensitivity of a transplantable adenocarcinoma of the large intestine].
    Eksperimental'naia onkologiia, 1990, Volume: 12, Issue:5

    Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Cell Line; Drug Resistance; Drug Screening Assays, Antit

1990
[Gastrointestinal hormones and cancers of the gastrointestinal tract].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Colonic Neoplasms; DNA Replication; Gastrins; Glu

1989
Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer.
    Gastroenterology, 1988, Volume: 95, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Gastrins; Glutamine; Humans; M

1988
Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice.
    Annals of surgery, 1985, Volume: 202, Issue:3

    Topics: Adenocarcinoma; Animals; Body Weight; Cell Division; Cell Line; Colon; Colonic Neoplasms; Gastric Fu

1985