proglumide has been researched along with Adenocarcinoma, Basal Cell in 12 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We performed a randomized, controlled study of gastrin receptor antagonist proglumide in 301 patients with cardiac adenocarcinoma after proximal subtotal gastrectomy." | 9.11 | Long-term effects of proglumide on resection of cardiac adenocarcinoma. ( Chen, YP; Liu, DT; Yang, JS; Yang, WP, 2005) |
| "Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist." | 9.06 | A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990) |
| "Nude mice bearing SW-1990 pancreatic cancer xenografts were injected with CCK (5, 15, or 25 micrograms/kg) or vehicle twice daily for 20 days." | 5.28 | Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990. ( Bagheri, S; Kramer, S; Smith, JP; Solomon, TE, 1990) |
| "We performed a randomized, controlled study of gastrin receptor antagonist proglumide in 301 patients with cardiac adenocarcinoma after proximal subtotal gastrectomy." | 5.11 | Long-term effects of proglumide on resection of cardiac adenocarcinoma. ( Chen, YP; Liu, DT; Yang, JS; Yang, WP, 2005) |
| "Forty-one patients with advanced colorectal cancer were entered into a randomized controlled trial of treatment with proglumide--a gastrin receptor antagonist." | 5.06 | A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer. ( Ballantyne, KC; Charnley, RM; Jones, J; Morris, DL, 1990) |
| " To evaluate the involvement of this hormone in the proliferation of gastric tumors, we studied the effects of gastrin/CCK-receptor antagonists (L365,260 and L364,718), proglumide and C terminal-specific gastrin antibodies on the human gastric adenocarcinoma cell line HGT-1." | 3.68 | Evidence for autocrine growth stimulation by a gastrin/CCK-like peptide of the gastric cancer HGT-1 cell line. ( Bali, JP; Chevillard, C; Laboisse, C; Laliberté, MF; Nonotte, I; Perrier-Meissonnier, S; Remy-Heintz, N, 1993) |
| "The effects of gastrin, proglumide (a gastrin receptor antagonist), and somatostatin on growth of human colon adenocarcinoma cell lines CX1, X56, and HT29 were examined in two experimental models." | 3.67 | Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer. ( Smith, JP; Solomon, TE, 1988) |
| "The incidence of pancreatic cancer appeared significantly (P < 0." | 1.29 | Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat. ( Alaggio, R; Behboo, R; Khajeturian, E; Militello, C; Pedrazzoli, S; Perasole, A; Rovati, L; Sperti, C, 1994) |
| "Nude mice bearing SW-1990 pancreatic cancer xenografts were injected with CCK (5, 15, or 25 micrograms/kg) or vehicle twice daily for 20 days." | 1.28 | Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990. ( Bagheri, S; Kramer, S; Smith, JP; Solomon, TE, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, JD | 1 |
| Wu, P | 1 |
| Huang, JX | 1 |
| Wu, J | 1 |
| Yang, G | 1 |
| Chen, YP | 1 |
| Yang, JS | 1 |
| Liu, DT | 1 |
| Yang, WP | 1 |
| Sperti, C | 1 |
| Militello, C | 1 |
| Rovati, L | 1 |
| Behboo, R | 1 |
| Khajeturian, E | 1 |
| Perasole, A | 1 |
| Alaggio, R | 1 |
| Pedrazzoli, S | 1 |
| Remy-Heintz, N | 1 |
| Perrier-Meissonnier, S | 1 |
| Nonotte, I | 1 |
| Laliberté, MF | 1 |
| Chevillard, C | 1 |
| Laboisse, C | 1 |
| Bali, JP | 1 |
| Funakoshi, A | 1 |
| Kono, A | 1 |
| Yactayo, S | 1 |
| Patrice, T | 1 |
| Foultier, MT | 1 |
| Berrada, A | 1 |
| Xu, XN | 1 |
| Morris, DL | 1 |
| Charnley, RM | 1 |
| Ballantyne, KC | 1 |
| Jones, J | 1 |
| Smith, JP | 2 |
| Solomon, TE | 2 |
| Bagheri, S | 1 |
| Kramer, S | 1 |
| Bershteĭn, LM | 1 |
| Zabezhinskiĭ, MA | 1 |
| Stukov, AN | 1 |
| Kalikhevich, VN | 1 |
| Mikheev, AM | 1 |
| Schusdziarra, V | 1 |
| Beauchamp, RD | 1 |
| Townsend, CM | 1 |
| Singh, P | 1 |
| Glass, EJ | 1 |
| Thompson, JC | 1 |
2 trials available for proglumide and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Long-term effects of proglumide on resection of cardiac adenocarcinoma.
Topics: Adenocarcinoma; Anti-Ulcer Agents; Combined Modality Therapy; Female; Heart Neoplasms; Humans; Male; | 2005 |
A pilot randomized control trial of proglumide (a gastrin receptor antagonist) in advanced colorectal cancer.
Topics: Adenocarcinoma; Carcinoembryonic Antigen; Colorectal Neoplasms; Humans; Liver Neoplasms; Neoplasm Re | 1990 |
10 other studies available for proglumide and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Role of ERK-MAPK signaling pathway in pentagastrin-regulated growth of large intestinal carcinoma.
Topics: Adenocarcinoma; Apoptosis; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; | 2014 |
Effect of cholecystokinin analogue caerulein and cholecystokinin antagonist lorglumide on pancreatic carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Ceruletide; Chi-Square Distr | 1994 |
Evidence for autocrine growth stimulation by a gastrin/CCK-like peptide of the gastric cancer HGT-1 cell line.
Topics: Adenocarcinoma; Antibodies; Benzodiazepinones; Cell Division; Devazepide; Gastrins; Growth Substance | 1993 |
Growth inhibition of human pancreatic cancer cells by cholecystokinin receptor antagonist in tissue culture and in nude mice.
Topics: Adenocarcinoma; Animals; Ceruletide; Cholecystokinin; Humans; In Vitro Techniques; Liver Neoplasms; | 1992 |
[Effect of gastrin and enprostil, a PGE2 analog, on colonic cancerous cell growth].
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Drug Combinations; Enprostil; Gastri | 1991 |
Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990.
Topics: Adenocarcinoma; Animals; Cholecystokinin; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; M | 1990 |
[The hormonal sensitivity of a transplantable adenocarcinoma of the large intestine].
Topics: Adenocarcinoma; Adenylyl Cyclases; Animals; Cell Line; Drug Resistance; Drug Screening Assays, Antit | 1990 |
[Gastrointestinal hormones and cancers of the gastrointestinal tract].
Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Colonic Neoplasms; DNA Replication; Gastrins; Glu | 1989 |
Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Gastrins; Glutamine; Humans; M | 1988 |
Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice.
Topics: Adenocarcinoma; Animals; Body Weight; Cell Division; Cell Line; Colon; Colonic Neoplasms; Gastric Fu | 1985 |