proglumetacin has been researched along with Rheumatism in 7 studies
proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-five patients with osteoarthritis, rheumatoid arthritis or spondyloarthritis, joint pain and other rheumatic-inflammatory disorders were treated with proglumetacin, at different doses, during 3-60 days." | 3.66 | [Proglumetacin: a flexible and broad-spectrum antirheumatic agent]. ( Fontanesi, G; Giancecchi, F; Rotini, R; Tartaglia, I, 1983) |
| "Proglumetacin was well-tolerated by all patients." | 1.26 | Proglumetacin (protacine): a promising new treatment of the rheumatic joint. ( Rivera, IC, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zanoli, S | 1 |
| Pace, N | 1 |
| Raffaelli, P | 1 |
| Floris, F | 1 |
| Fontanesi, G | 1 |
| Giancecchi, F | 1 |
| Rotini, R | 1 |
| Tartaglia, I | 1 |
| Benvenuti, M | 1 |
| Albanese, L | 1 |
| Pagliara, L | 1 |
| Rivera, IC | 1 |
| Branco do Amaral, A | 1 |
| Pipitone, V | 1 |
| Loizzi, P | 1 |
| Casula, PL | 1 |
| Bignamini, AA | 1 |
1 trial available for proglumetacin and Rheumatism
| Article | Year |
|---|---|
Double-blind clinical evaluation of a new anti-inflammatory drug, protacine, versus indomethacin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Humans | 1979 |
6 other studies available for proglumetacin and Rheumatism
| Article | Year |
|---|---|
[Short-term study of proglumetacin].
Topics: Adult; Aged; Back Pain; Brachial Plexus Neuritis; Drug Evaluation; Drug Tolerance; Female; Humans; I | 1983 |
[Proglumetacin: a flexible and safe anti-inflammatory agent for effective clinical practice].
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Drug Eval | 1983 |
[Proglumetacin: a flexible and broad-spectrum antirheumatic agent].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Drug Evaluation; Drug Tolerance; Female; Huma | 1983 |
[Clinico-statistical study on the anti-inflammatory activity of proglumetacin. Proglumetacin: at last a complete anti-inflammatory agent?].
Topics: Adult; Aged; Drug Evaluation; Drug Tolerance; Female; Gout; Humans; Indoleacetic Acids; Intervertebr | 1983 |
Proglumetacin (protacine): a promising new treatment of the rheumatic joint.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Humans; Indoleacetic Acids; Jo | 1982 |
Short-term and long-term open evaluation of the efficacy and tolerance of proglumetacin, a new antirheumatic agent.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Chronic Disease; Female; Humans; Indoleacetic Acids; Mal | 1982 |