proglumetacin has been researched along with Pain in 7 studies
proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An open, multicentre, outpatient study involving 77 Italian orthopaedic and rheumatology centres was conducted to evaluate the efficacy and tolerability of proglumetacin in the treatment of arthritis of the hip and of the knee." | 7.67 | Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study. ( Antonini, P; Carratelli, L; Messina, E; Pica, B, 1985) |
| "Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III." | 7.66 | [Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983) |
| "Thirty patients with articular pain had been treated with proglumetacin during average 12 days." | 7.66 | [Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983) |
| "An open, multicentre, outpatient study involving 77 Italian orthopaedic and rheumatology centres was conducted to evaluate the efficacy and tolerability of proglumetacin in the treatment of arthritis of the hip and of the knee." | 3.67 | Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study. ( Antonini, P; Carratelli, L; Messina, E; Pica, B, 1985) |
| "Fifty-five patients with osteoarthritis, rheumatoid arthritis or spondyloarthritis, joint pain and other rheumatic-inflammatory disorders were treated with proglumetacin, at different doses, during 3-60 days." | 3.66 | [Proglumetacin: a flexible and broad-spectrum antirheumatic agent]. ( Fontanesi, G; Giancecchi, F; Rotini, R; Tartaglia, I, 1983) |
| "Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III." | 3.66 | [Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983) |
| "Thirty patients with articular pain had been treated with proglumetacin during average 12 days." | 3.66 | [Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983) |
| "Proglumetacin was administered as a sole treatment during 15 days at 450 mg/day to 20 patients with osteoarthritis localized in several joints." | 1.27 | [Short-term effects of proglumetacin in arthrosis]. ( Fioravanti, A; Giordano, N; Marcolongo, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Floris, F | 1 |
| Fontanesi, G | 1 |
| Giancecchi, F | 1 |
| Rotini, R | 1 |
| Tartaglia, I | 1 |
| Montrone, F | 1 |
| Fumagalli, M | 1 |
| Boccassini, L | 1 |
| Greco, M | 1 |
| Caruso, I | 1 |
| Marcolongo, R | 1 |
| Giordano, N | 1 |
| Fioravanti, A | 1 |
| Ardito, S | 1 |
| Leonardi, W | 1 |
| Longo, G | 1 |
| Lorenzi, GL | 1 |
| Bertini, G | 1 |
| Peveraro, A | 1 |
| Carratelli, L | 1 |
| Antonini, P | 1 |
| Messina, E | 1 |
| Pica, B | 1 |
7 other studies available for proglumetacin and Pain
| Article | Year |
|---|---|
[Proglumetacin: a flexible and safe anti-inflammatory agent for effective clinical practice].
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Drug Eval | 1983 |
[Proglumetacin: a flexible and broad-spectrum antirheumatic agent].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Drug Evaluation; Drug Tolerance; Female; Huma | 1983 |
[Proglumetacine in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Tolerance; Female; Humans; Indoleacetic Ac | 1983 |
[Short-term effects of proglumetacin in arthrosis].
Topics: Drug Evaluation; Drug Tolerance; Humans; Indoleacetic Acids; Joint Diseases; Muscle Rigidity; Pain | 1983 |
[Proglumetacin: a simple and practical anti-inflammatory agent for the treatment of hospitalized orthopedic patients].
Topics: Adolescent; Adult; Aged; Arthritis; Bursitis; Child; Drug Evaluation; Drug Tolerance; Female; Humans | 1983 |
[Proglumetacin for fast and safe control of joint pain of orthopedic importance].
Topics: Adult; Aged; Arm; Drug Evaluation; Drug Tolerance; Female; Hand; Humans; Indoleacetic Acids; Joint D | 1983 |
Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study.
Topics: Adult; Aged; Arthritis; Female; Hip Joint; Humans; Indoleacetic Acids; Knee Joint; Male; Middle Aged | 1985 |