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proglumetacin and Pain

proglumetacin has been researched along with Pain in 7 studies

proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"An open, multicentre, outpatient study involving 77 Italian orthopaedic and rheumatology centres was conducted to evaluate the efficacy and tolerability of proglumetacin in the treatment of arthritis of the hip and of the knee."7.67Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study. ( Antonini, P; Carratelli, L; Messina, E; Pica, B, 1985)
"Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III."7.66[Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983)
"Thirty patients with articular pain had been treated with proglumetacin during average 12 days."7.66[Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983)
"An open, multicentre, outpatient study involving 77 Italian orthopaedic and rheumatology centres was conducted to evaluate the efficacy and tolerability of proglumetacin in the treatment of arthritis of the hip and of the knee."3.67Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study. ( Antonini, P; Carratelli, L; Messina, E; Pica, B, 1985)
"Fifty-five patients with osteoarthritis, rheumatoid arthritis or spondyloarthritis, joint pain and other rheumatic-inflammatory disorders were treated with proglumetacin, at different doses, during 3-60 days."3.66[Proglumetacin: a flexible and broad-spectrum antirheumatic agent]. ( Fontanesi, G; Giancecchi, F; Rotini, R; Tartaglia, I, 1983)
"Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III."3.66[Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983)
"Thirty patients with articular pain had been treated with proglumetacin during average 12 days."3.66[Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983)
"Proglumetacin was administered as a sole treatment during 15 days at 450 mg/day to 20 patients with osteoarthritis localized in several joints."1.27[Short-term effects of proglumetacin in arthrosis]. ( Fioravanti, A; Giordano, N; Marcolongo, R, 1983)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Floris, F1
Fontanesi, G1
Giancecchi, F1
Rotini, R1
Tartaglia, I1
Montrone, F1
Fumagalli, M1
Boccassini, L1
Greco, M1
Caruso, I1
Marcolongo, R1
Giordano, N1
Fioravanti, A1
Ardito, S1
Leonardi, W1
Longo, G1
Lorenzi, GL1
Bertini, G1
Peveraro, A1
Carratelli, L1
Antonini, P1
Messina, E1
Pica, B1

Other Studies

7 other studies available for proglumetacin and Pain

ArticleYear
[Proglumetacin: a flexible and safe anti-inflammatory agent for effective clinical practice].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Drug Eval

1983
[Proglumetacin: a flexible and broad-spectrum antirheumatic agent].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Drug Evaluation; Drug Tolerance; Female; Huma

1983
[Proglumetacine in rheumatoid arthritis].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Tolerance; Female; Humans; Indoleacetic Ac

1983
[Short-term effects of proglumetacin in arthrosis].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Drug Evaluation; Drug Tolerance; Humans; Indoleacetic Acids; Joint Diseases; Muscle Rigidity; Pain

1983
[Proglumetacin: a simple and practical anti-inflammatory agent for the treatment of hospitalized orthopedic patients].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Adolescent; Adult; Aged; Arthritis; Bursitis; Child; Drug Evaluation; Drug Tolerance; Female; Humans

1983
[Proglumetacin for fast and safe control of joint pain of orthopedic importance].
    Minerva medica, 1983, Jun-23, Volume: 74, Issue:26

    Topics: Adult; Aged; Arm; Drug Evaluation; Drug Tolerance; Female; Hand; Humans; Indoleacetic Acids; Joint D

1983
Proglumetacin in arthritis of the hip and the knee. Results of a post-marketing surveillance study.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4

    Topics: Adult; Aged; Arthritis; Female; Hip Joint; Humans; Indoleacetic Acids; Knee Joint; Male; Middle Aged

1985