proglumetacin has been researched along with Muscle Rigidity in 3 studies
proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III." | 7.66 | [Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983) |
| "Proglumetacin, 450 mg/day, was administered during 1 month to 32 rheumatoid arthritis patients in anatomical and functional stage II or III." | 3.66 | [Proglumetacine in rheumatoid arthritis]. ( Boccassini, L; Caruso, I; Fumagalli, M; Greco, M; Montrone, F, 1983) |
| "Proglumetacin was administered as a sole treatment during 15 days at 450 mg/day to 20 patients with osteoarthritis localized in several joints." | 1.27 | [Short-term effects of proglumetacin in arthrosis]. ( Fioravanti, A; Giordano, N; Marcolongo, R, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Floris, F | 1 |
| Montrone, F | 1 |
| Fumagalli, M | 1 |
| Boccassini, L | 1 |
| Greco, M | 1 |
| Caruso, I | 1 |
| Marcolongo, R | 1 |
| Giordano, N | 1 |
| Fioravanti, A | 1 |
3 other studies available for proglumetacin and Muscle Rigidity
| Article | Year |
|---|---|
[Proglumetacin: a flexible and safe anti-inflammatory agent for effective clinical practice].
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Drug Eval | 1983 |
[Proglumetacine in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Tolerance; Female; Humans; Indoleacetic Ac | 1983 |
[Short-term effects of proglumetacin in arthrosis].
Topics: Drug Evaluation; Drug Tolerance; Humans; Indoleacetic Acids; Joint Diseases; Muscle Rigidity; Pain | 1983 |