proglumetacin has been researched along with Joint Diseases in 9 studies
proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
Joint Diseases: Diseases involving the JOINTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty patients with articular pain had been treated with proglumetacin during average 12 days." | 7.66 | [Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983) |
| "6 +/- 12,9 years) with orthopedic-traumatologic disorders (osteoarthritis, 38; painful joints, 26; fibrositis, painful shoulder, 20; peri- and extra-articular disorders, 13) had been treated during 7 to 30 days with two suppositories (400 mg) or three capsules (450 mg) proglumetacin (Proxil Rorer)." | 5.05 | [Proglumetacin: possible first choice in the treatment of orthopedic- traumatologic disorders]. ( Gusso, MI; Guzzo, GC; Pennisi, M, 1985) |
| "Twenty-nine patients with gouty arthritis, rheumatoid arthritis and osteoarthritis were treated as outpatients with proglumetacin, at different doses, during 5-30 days." | 3.66 | [Proglumetacin for a wide spectrum of activity in clinical medicine]. ( Fossaluzza, V, 1983) |
| "Thirty patients with articular pain had been treated with proglumetacin during average 12 days." | 3.66 | [Proglumetacin for fast and safe control of joint pain of orthopedic importance]. ( Bertini, G; Lorenzi, GL; Peveraro, A, 1983) |
| "Proglumetacin was administered as a sole treatment during 15 days at 450 mg/day to 20 patients with osteoarthritis localized in several joints." | 1.27 | [Short-term effects of proglumetacin in arthrosis]. ( Fioravanti, A; Giordano, N; Marcolongo, R, 1983) |
| "Proglumetacin was well-tolerated by all patients." | 1.26 | Proglumetacin (protacine): a promising new treatment of the rheumatic joint. ( Rivera, IC, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zanoli, S | 1 |
| Pace, N | 1 |
| Raffaelli, P | 1 |
| Tonon, R | 1 |
| Simioni, M | 1 |
| Lazzarin, P | 1 |
| Bedendo, A | 1 |
| Todesco, S | 1 |
| Marcolongo, R | 1 |
| Giordano, N | 1 |
| Fioravanti, A | 1 |
| Fossaluzza, V | 1 |
| Larosa, F | 1 |
| Vittore, D | 1 |
| Mazzarisi, A | 1 |
| Molfetta, L | 1 |
| Ardito, S | 1 |
| Leonardi, W | 1 |
| Longo, G | 1 |
| Lorenzi, GL | 1 |
| Bertini, G | 1 |
| Peveraro, A | 1 |
| Rivera, IC | 1 |
| Gusso, MI | 1 |
| Guzzo, GC | 1 |
| Pennisi, M | 1 |
1 trial available for proglumetacin and Joint Diseases
| Article | Year |
|---|---|
[Proglumetacin: possible first choice in the treatment of orthopedic- traumatologic disorders].
Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Fi | 1985 |
8 other studies available for proglumetacin and Joint Diseases
| Article | Year |
|---|---|
[Short-term study of proglumetacin].
Topics: Adult; Aged; Back Pain; Brachial Plexus Neuritis; Drug Evaluation; Drug Tolerance; Female; Humans; I | 1983 |
[Proglumetacin for the treatment of inflammatory and degenerative arthropathies].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Tolerance; Female; Humans; Indoleacetic Acids; Joint Diseas | 1984 |
[Short-term effects of proglumetacin in arthrosis].
Topics: Drug Evaluation; Drug Tolerance; Humans; Indoleacetic Acids; Joint Diseases; Muscle Rigidity; Pain | 1983 |
[Proglumetacin for a wide spectrum of activity in clinical medicine].
Topics: Adult; Aged; Arthritis, Rheumatoid; Diabetes Complications; Drug Tolerance; Female; Gout; Humans; In | 1983 |
[Joint pain crises and chronic inflammatory-reactive phenomena: a unitary approach with proglumetacin].
Topics: Acute Disease; Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Tolerance; Female; Humans; | 1983 |
[Proglumetacin: a simple and practical anti-inflammatory agent for the treatment of hospitalized orthopedic patients].
Topics: Adolescent; Adult; Aged; Arthritis; Bursitis; Child; Drug Evaluation; Drug Tolerance; Female; Humans | 1983 |
[Proglumetacin for fast and safe control of joint pain of orthopedic importance].
Topics: Adult; Aged; Arm; Drug Evaluation; Drug Tolerance; Female; Hand; Humans; Indoleacetic Acids; Joint D | 1983 |
Proglumetacin (protacine): a promising new treatment of the rheumatic joint.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Humans; Indoleacetic Acids; Jo | 1982 |