proglumetacin has been researched along with Allergic Reaction in 1 studies
proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.
Excerpt | Relevance | Reference |
---|---|---|
"The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats." | 7.67 | Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987) |
"The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats." | 3.67 | Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ono, N | 1 |
Sunami, A | 1 |
Yamasaki, Y | 1 |
Yamamoto, N | 1 |
Miyake, H | 1 |
1 other study available for proglumetacin and Allergic Reaction
Article | Year |
---|---|
Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dinoprostone; | 1987 |