Page last updated: 2024-11-03

proglumetacin and Allergic Reaction

proglumetacin has been researched along with Allergic Reaction in 1 studies

proglumetacin : A carboxylic ester obtained by formal condensation of the carboxy group of indometacin with the hydroxy group of 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl N(2)-benzoyl-N,N-dipropyl-alpha-glutaminate. Used (as its dimaleate salt) to control pain and inflammation associated with musculoskeletal and joint disorders. Following oral administration, it is metabolised to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.

Research Excerpts

ExcerptRelevanceReference
"The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats."7.67Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987)
"The mechanism of the anti-inflammatory effect of proglumetacin maleate, a novel indomethacin derivative, was examined in vivo in an allergic air pouch inflammation model in rats."3.67Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats. ( Miyake, H; Ono, N; Sunami, A; Yamamoto, N; Yamasaki, Y, 1987)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ono, N1
Sunami, A1
Yamasaki, Y1
Yamamoto, N1
Miyake, H1

Other Studies

1 other study available for proglumetacin and Allergic Reaction

ArticleYear
Effects of proglumetacin maleate and its major metabolites on allergic air pouch inflammation in rats.
    European journal of pharmacology, 1987, Oct-13, Volume: 142, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dinoprostone;

1987