procyclidine has been researched along with Schizophrenia in 40 studies
Procyclidine: A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
procyclidine : A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a series of 36 patients with acute schizophrenia flupenthixol dosage was blindly adjusted to give a fixed level of sedation." | 5.05 | Adverse effects of anticholinergic medication on positive schizophrenic symptoms. ( Bourne, RC; Crow, TJ; Ferrier, IN; Frith, CD; Gamble, SJ; Johnstone, EC; Owens, DG, 1983) |
| "A double-blind, cross-over trial of the effectiveness of piribedil, procyclidine and placebo in the control of parkinsonism induced by fluphenazine decanoate was conducted in sixteen cases of chronic schizophrenia." | 5.04 | A comparison of piribedil, procyclidine and placebo in the control of phenothiazine-induced parkinsonism. ( Bradley, R; Lamb, P; Mindham, RH, 1977) |
| "To determine whether the use or the withdrawal of anticholinergic drugs (benzhexol, benztropine, biperiden, orphenadrine, procyclidine, scopolamine, or trihexylphenidyl) are clinically effective for the treatment of people with both antipsychotic-induced tardive dyskinesia and schizophrenia or other chronic mental illnesses." | 4.98 | Anticholinergic medication for antipsychotic-induced tardive dyskinesia. ( Bergman, H; Soares-Weiser, K, 2018) |
| "Procyclidine was administered to 25 chronic psychotic inpatients, stabilised on chlorpromazine, haloperidol or fluphenazine decanoate injection." | 2.66 | Interactions between procyclidine and neuroleptic drugs. Some pharmacological and clinical aspects. ( Bamrah, JS; Krska, J; Kumar, V; Soni, SD, 1986) |
| "In recent years, the complex treatment of schizophrenia has been extended by the neuroleptic large-dose therapy." | 1.26 | [Neuroleptic large dose therapy of schizophrenias]. ( Pethö, B; Ungvári, G, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (80.00) | 18.7374 |
| 1990's | 4 (10.00) | 18.2507 |
| 2000's | 3 (7.50) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergman, H | 1 |
| Soares-Weiser, K | 1 |
| Ettinger, U | 2 |
| Kumari, V | 3 |
| Zachariah, E | 3 |
| Galea, A | 2 |
| Crawford, TJ | 2 |
| Corr, PJ | 1 |
| Taylor, D | 2 |
| Das, M | 2 |
| Sharma, T | 3 |
| BLUMBERG, AG | 1 |
| Warnes, H | 1 |
| Ungvári, G | 1 |
| Pethö, B | 1 |
| Bennie, EH | 1 |
| Johnstone, EC | 2 |
| Crow, TJ | 2 |
| Ferrier, IN | 1 |
| Frith, CD | 1 |
| Owens, DG | 1 |
| Bourne, RC | 1 |
| Gamble, SJ | 1 |
| Thornton, A | 1 |
| McKenna, PJ | 1 |
| Spivak, B | 1 |
| Gonen, N | 1 |
| Mester, R | 1 |
| Averbuch, E | 1 |
| Adlersberg, S | 1 |
| Weizman, A | 1 |
| Mehrotra, R | 1 |
| Ruprah, M | 1 |
| Gründig, E | 1 |
| Weiss, J | 1 |
| Chouinard, G | 5 |
| Annable, L | 5 |
| Ross-Chouinard, A | 2 |
| Nestoros, JN | 1 |
| De Montigny, C | 1 |
| Kropsky, ML | 1 |
| Rifkin, A | 1 |
| Quitkin, F | 1 |
| Kane, J | 1 |
| Struve, F | 1 |
| Klein, DF | 2 |
| Mindham, RH | 1 |
| Lamb, P | 1 |
| Bradley, R | 1 |
| Cooper, S | 1 |
| McClelleand, HA | 1 |
| Cookson, IB | 1 |
| Owen, F | 1 |
| Ridges, AP | 1 |
| Burrell, MF | 1 |
| Fewster, C | 1 |
| Szabadi, E | 1 |
| Cashman, M | 1 |
| Schifano, F | 1 |
| di Costanzo, E | 1 |
| Perényi, A | 1 |
| Goswami, U | 1 |
| Frecska, E | 1 |
| Majláth, E | 1 |
| Barcs, G | 1 |
| Kassay-Farkas, A | 1 |
| Deahl, M | 1 |
| Bamrah, JS | 1 |
| Kumar, V | 1 |
| Krska, J | 1 |
| Soni, SD | 1 |
| Saletu, B | 1 |
| Küfferle, B | 1 |
| Grünberger, J | 1 |
| Anderer, P | 1 |
| Mercier, P | 1 |
| Turnier, L | 1 |
| Dinan, TG | 1 |
| Itil, TM | 1 |
| Gannon, P | 1 |
| Hsu, W | 2 |
| Klingenberg, H | 1 |
| Seeman, MV | 1 |
| Denber, HC | 1 |
| Goldner, F | 1 |
| Caston, JC | 1 |
| Randels, PM | 1 |
| Keeler, MA | 1 |
| Klett, CJ | 1 |
| Caffey, E | 1 |
| Honigfeld, G | 1 |
| Feldman, S | 1 |
| Bucci, L | 2 |
| Villeneuve, A | 1 |
| Pecknold, JC | 1 |
| Ananth, JV | 1 |
| Ban, TA | 1 |
| Lehmann, HE | 1 |
| Kline, NS | 1 |
| Keskiner, A | 1 |
| Itil, T | 1 |
| Han, H | 1 |
| Ulett, G | 1 |
| Silverman, M | 1 |
| Lopes, WP | 1 |
1 review available for procyclidine and Schizophrenia
| Article | Year |
|---|---|
Anticholinergic medication for antipsychotic-induced tardive dyskinesia.
Topics: Antipsychotic Agents; Biperiden; Cholinergic Antagonists; Dyskinesia, Drug-Induced; Humans; Isocarbo | 2018 |
14 trials available for procyclidine and Schizophrenia
| Article | Year |
|---|---|
Effects of procyclidine on eye movements in schizophrenia.
Topics: Adult; Analysis of Variance; Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Electroo | 2003 |
Adverse effects of anticholinergic medication on positive schizophrenic symptoms.
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Extrapyramidal Tracts; Female; F | 1983 |
Effects of oral procyclidine administration on cognitive functions in healthy subjects: implications for schizophrenia.
Topics: Administration, Oral; Adult; Cholinergic Antagonists; Cognition Disorders; Dose-Response Relationshi | 2002 |
Ethopropazine and benztropine in neuroleptic-induced parkinsonism.
Topics: Adult; Benztropine; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; Female; | 1979 |
Are prophylactic antiparkinson drugs necessary? A controlled study of procyclidine withdrawal.
Topics: Adult; Aftercare; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; D | 1978 |
A comparison of piribedil, procyclidine and placebo in the control of phenothiazine-induced parkinsonism.
Topics: Chronic Disease; Clinical Trials as Topic; Fluphenazine; Humans; Parkinson Disease; Parkinson Diseas | 1977 |
A pilot study of the role of prophylactic antiparkinson treatment during neuroleptic therapy.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; Haloperidol; Hu | 1989 |
Interactions between procyclidine and neuroleptic drugs. Some pharmacological and clinical aspects.
Topics: Adult; Aged; Antipsychotic Agents; Clinical Trials as Topic; Drug Interactions; Female; Humans; Male | 1986 |
Quantitative EEG, SPEM, and psychometric studies in schizophrenics before and during differential neuroleptic therapy.
Topics: Adult; Antipsychotic Agents; Attention; Brain; Dibenzazepines; Electroencephalography; Eye Movements | 1986 |
Long-term effects of L-dopa and procyclidine on neuroleptic-induced extrapyramidal and schizophrenic symptoms.
Topics: Adult; Antipsychotic Agents; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease, Seconda | 1987 |
Evaluating the long-term need for antiparkinson drugs by chronic schizophrenics.
Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Benztropine; Biperiden; Chronic Dis | 1972 |
Prediction of drug effect by diagnostic decision tree.
Topics: Anxiety; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Factor Analysis, St | 1968 |
The dyskenesias: a new therapeutic approach.
Topics: Chlorpromazine; Clinical Trials as Topic; Female; Humans; Isocarboxazid; Male; Middle Aged; Monoamin | 1971 |
EEG changes after fluphenazine enanthate and decanoate based on analog power spectra and digital computer period analysis.
Topics: Adult; Brain; Computers; Delayed-Action Preparations; Electroencephalography; Female; Fluphenazine; | 1971 |
25 other studies available for procyclidine and Schizophrenia
| Article | Year |
|---|---|
EFFECT OF CHLORPROMAZINE WITH PROCYCLIDINE AND IMIPRAMINE ON RADIOACTIVE IODINE UPTAKE.
Topics: Chlorpromazine; Humans; Imipramine; Iodine; Iodine Isotopes; Neurotic Disorders; Parasympatholytics; | 1963 |
Lack of association between prepulse inhibition and antisaccadic deficits in chronic schizophrenia: implications for identification of schizophrenia endophenotypes.
Topics: Adult; Aged; Blinking; Diagnostic and Statistical Manual of Mental Disorders; Electromyography; Elec | 2005 |
Toxic psychosis due to antiparkinsonian drugs.
Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Male; Middle Aged; Paranoid Disorders; Parasymp | 1967 |
[Neuroleptic large dose therapy of schizophrenias].
Topics: Acute Disease; Adult; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1981 |
Antiparkinsonian medication in depressed schizophrenics on depot neuroleptics.
Topics: Antipsychotic Agents; Humans; Procyclidine; Pyrrolidines; Schizophrenia; Trihexyphenidyl | 1982 |
Acute dystonic reactions complicated by psychotic phenomena.
Topics: Adult; Aged; Antipsychotic Agents; Chronic Disease; Diagnosis, Differential; Dose-Response Relations | 1994 |
Neuroleptic malignant syndrome associated with abrupt withdrawal of anticholinergic agents.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Male; Muscarinic Ant | 1996 |
[The influence of neuroleptic drugs on urinary excretion of non-protein nitrogen (author's transl)].
Topics: Amino Acids; Clopenthixol; Clozapine; Creatinine; Delayed-Action Preparations; Flupenthixol; Fluphen | 1976 |
Factors related to tardive dyskinesia.
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; Fluphenazine; Foll | 1979 |
Tardive dyskinesia and antiparkinsonian medication.
Topics: Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Park | 1979 |
Antiparkinsonian drug administration and plasma levels of penfluridol, a new long-acting neuroleptic.
Topics: Adult; Antiparkinson Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Penfluridol; Pi | 1977 |
The coincidence of schizophrenia and Parkinsonism: some neurochemical implications.
Topics: Aged; Delusions; Dopamine; Female; Hallucinations; Humans; Middle Aged; Parkinson Disease, Postencep | 1976 |
Platelet monoamine oxidase activity during the course of a schizophreniform psychosis.
Topics: Blood Platelets; Cognition Disorders; Delusions; Emotions; Hallucinations; Haloperidol; Humans; Male | 1975 |
Clozapine-treated NMS.
Topics: Adult; Chlorpromazine; Clopenthixol; Clozapine; Drug Therapy, Combination; Humans; Male; Neuroleptic | 1991 |
Excessive use of anticholinergic drugs in a sub-sample of Italian schizophrenics.
Topics: Adult; Biperiden; Female; Humans; Italy; Male; Middle Aged; Orphenadrine; Parasympatholytics; Patien | 1991 |
Betel nut-induced extrapyramidal syndrome: an unusual drug interaction.
Topics: Antipsychotic Agents; Areca; Arecoline; Basal Ganglia Diseases; Drug Interactions; Drug Therapy, Com | 1989 |
Neuroleptic effects on platelet aggregation: a study in normal volunteers and schizophrenics.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Delayed-Action Preparations; Flupenthixol; | 1987 |
Digital computer analyzed sleep and resting EEG during haloperidol treatment.
Topics: Adult; Analysis of Variance; Animals; Arousal; Computers; Diagnosis, Computer-Assisted; Electroencep | 1970 |
Paradoxical effects of phenothiazines.
Topics: Adult; Amitriptyline; Chlorpromazine; Diazepam; Female; Humans; Meclofenoxate; Meprobamate; Phenothi | 1968 |
Intoxication with procyclidine (kemadrin), report of three cases.
Topics: 1-Propanol; Adult; Antiparkinson Agents; Basal Ganglia Diseases; Female; Humans; Male; Procyclidine; | 1973 |
Combined intramuscular administration of depot fluphenazine and benztropinemesylate in chronic schizophrenic patients.
Topics: 1-Propanol; Adult; Fluphenazine; Humans; Injections, Intramuscular; Male; Movement Disorders; Parasy | 1971 |
The rabbit syndrome. A peculiar extrapyramidal reaction.
Topics: Aged; Anxiety; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Fatigue; Female; Humans; Male; M | 1972 |
Lack of indication for use of antiparkinson medication. A follow-up study.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Intellectual Disability; Male; Mental Disorder | 1971 |
Greater than recommended drug dosages--some effects.
Topics: Adult; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Movement Disorders; Procyclidine; | 1970 |
Fluphenazine enanthate in the maintenance treatment of schizophrenia.
Topics: Fluphenazine; Humans; Orphenadrine; Procyclidine; Schizophrenia | 1968 |