procyclidine has been researched along with Organophosphorus Poisoning in 3 studies
Procyclidine: A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
procyclidine : A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The treatment was given 1 and 5 min after exposure to a supralethal dose of nerve agents, and the results showed that the triple regimen successfully prevented or terminated seizures and preserved the lives of rats exposed to 5×LD50 of soman, sarin, cyclosarin, or VX, but solely 3×LD50 of tabun was managed by this regimen." | 3.81 | Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats. ( Aas, P; Enger, S; Mariussen, E; Myhrer, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Myhrer, T | 2 |
| Aas, P | 2 |
| Mariussen, E | 1 |
| Enger, S | 1 |
| Joosen, MJ | 1 |
| van der Schans, MJ | 1 |
| Kuijpers, WC | 1 |
| van Helden, HP | 1 |
| Noort, D | 1 |
2 reviews available for procyclidine and Organophosphorus Poisoning
| Article | Year |
|---|---|
Choice of approaches in developing novel medical countermeasures for nerve agent poisoning.
Topics: Animals; Anticonvulsants; Antidotes; Brain; Cholinergic Agents; Humans; Levetiracetam; Organophospha | 2014 |
Timing of decontamination and treatment in case of percutaneous VX poisoning: a mini review.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibi | 2013 |
1 other study available for procyclidine and Organophosphorus Poisoning
| Article | Year |
|---|---|
Supralethal poisoning by any of the classical nerve agents is effectively counteracted by procyclidine regimens in rats.
Topics: Animals; Anticonvulsants; Antidotes; Body Weight; Brain; Disease Models, Animal; Dose-Response Relat | 2015 |