procyclidine has been researched along with Muscle Rigidity in 3 studies
Procyclidine: A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
procyclidine : A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of abdominal pain with rigidity, mimicking an acute abdomen, caused by metoclopramide, a common anti-emetic drug." | 7.73 | Abdominal pain with rigidity secondary to the anti-emetic drug metoclopramide. ( Khan, NU; Razzak, JA, 2006) |
| "High dose intravenous therapy with the anticholinergic drug, procyclidine hydrochloride, temporarily diminished the muscle rigidity and reversed most of the autonomic features in a patient with NMS occurring after a single intramuscular dose of the dopamine antagonist metoclopramide." | 7.69 | Paradoxical autonomic response to procyclidine in the neuroleptic malignant syndrome. ( Balzan, MV, 1995) |
| "We report a case of abdominal pain with rigidity, mimicking an acute abdomen, caused by metoclopramide, a common anti-emetic drug." | 3.73 | Abdominal pain with rigidity secondary to the anti-emetic drug metoclopramide. ( Khan, NU; Razzak, JA, 2006) |
| "High dose intravenous therapy with the anticholinergic drug, procyclidine hydrochloride, temporarily diminished the muscle rigidity and reversed most of the autonomic features in a patient with NMS occurring after a single intramuscular dose of the dopamine antagonist metoclopramide." | 3.69 | Paradoxical autonomic response to procyclidine in the neuroleptic malignant syndrome. ( Balzan, MV, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, NU | 1 |
| Razzak, JA | 1 |
| Balzan, MV | 1 |
| Butzer, JF | 1 |
| Silver, DE | 1 |
| Sahs, AL | 1 |
1 trial available for procyclidine and Muscle Rigidity
| Article | Year |
|---|---|
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine | 1975 |
2 other studies available for procyclidine and Muscle Rigidity
| Article | Year |
|---|---|
Abdominal pain with rigidity secondary to the anti-emetic drug metoclopramide.
Topics: Abdomen, Acute; Abdominal Muscles; Abdominal Pain; Adult; Antiemetics; Antimalarials; Chloroquine; D | 2006 |
Paradoxical autonomic response to procyclidine in the neuroleptic malignant syndrome.
Topics: Autonomic Nervous System; Hernia; Humans; Injections, Intravenous; Male; Middle Aged; Muscle Rigidit | 1995 |