procyanidin has been researched along with Innate Inflammatory Response in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (10.87) | 29.6817 |
| 2010's | 54 (58.70) | 24.3611 |
| 2020's | 28 (30.43) | 2.80 |
| Authors | Studies |
|---|---|
| Midttun, HLE; Mueller-Harvey, I; Ramsay, A; Williams, AR | 1 |
| Yi, YS | 1 |
| Ardévol, A; Blay, M; Castell-Auví, A; Cedó, L; Fernández-Iglesias, A; Garcia-Vallvé, S; Pallarès, V; Pinent, M; Salvadó, MJ | 1 |
| Delvin, E; Denis, MC; Desjardins, Y; Dudonné, S; Furtos, A; Garofalo, C; Levy, E; Marcil, V; Marette, A; Montoudis, A | 1 |
| Arola, L; Arola-Arnal, A; Caimari, A; Crescenti, A; del Bas, JM; Oms-Oliu, G | 1 |
| Bitzer, ZT; Dorenkott, MR; Glisan, SL; Goodrich, KM; Lambert, JD; Neilson, AP; O'Keefe, SF; Ye, L | 1 |
| Çiçek, SS; Faraone, I; Halim, MA; Haque, MA; Milella, L; Rahman, MM; Sönnichsen, FD; Uddin, MJ; Zidorn, C | 1 |
| Andersen-Civil, AIS; Büdeyri Gökgöz, N; Engström, MT; Krych, L; Lauridsen, C; Mejer, H; Myhill, LJ; Nielsen, DS; Salminen, JP; Thamsborg, SM; Williams, AR; Zeller, WE; Zhu, L | 1 |
| Chen, H; Deng, G; Li, Y; Lin, X; Liu, Y; Shen, S; Sun, R; Wei, Y; Wu, L | 1 |
| Chen, H; Han, X; Xiaofu, Z; Yuan, J; Zhang, Z; Zhao, W; Zhou, Q | 1 |
| Cui, C; Ren, H; Wang, F; Wang, N; Xu, C; Yu, Q; Zhang, G | 1 |
| Guo, M; Li, X; Song, J; Xian, D; Xie, Y; Zhao, Y; Zhong, J | 1 |
| Chen, XY; Deng, L; Du, Y; Lv, YW; Ma, SS; Shi, YC; Xu, HC | 1 |
| Chen, S; Fu, L; Huangfu, H; Qin, Q; Ren, S; Wang, D; Wang, H; Zhang, Y; Zhou, Y | 1 |
| Andersone, A; Janceva, S; Lauberte, L; Nikolajeva, V; Ramata-Stunda, A; Rieksts, G; Telysheva, G; Zaharova, N | 1 |
| Deng, X; Dong, Y; Hu, B; Liu, S; Luo, Y; Ma, Y; Pu, J; Wang, G; Yang, F; Zhan, J; Zhou, W; Zhu, T | 1 |
| Arjsri, P; Dejkriengkraikul, P; Jamjod, S; Prom-U-Thai, C; Semmarath, W; Srisawad, K; Umsumarng, S; Yodkeeree, S | 1 |
| Li, WW; Liu, X; Liu, YQ; Qu, W | 1 |
| Aragonès, G; Ardid-Ruiz, A; Barna, L; Bladé, C; Deli, MA; Harazin, A; Suárez, M; Walter, FR | 1 |
| Gui, S; Jiang, Y; Wang, X; Yang, W | 1 |
| García-Villanova, B; Guerra-Hernández, E; Rodríguez-Pérez, C; Verardo, V | 1 |
| Chen, S; Du, LJ; Feng, J; Gao, H; Han, S; Li, J; Li, JX; Li, X; Luo, YY; Wang, Q; Yang, S; Zhao, LC | 1 |
| Hu, S; Liu, J; Shao, S; Yuan, L; Zhu, B | 1 |
| Ardévol, A; Beltrán-Debón, R; Blay, MT; González-Quilen, C; Pinent, M; Rodríguez-Gallego, E; Terra, X | 1 |
| Huang, J; Jin, S; Li, S; Liu, L; Song, A; Yang, P; Zhang, L; Zhang, Y | 1 |
| Ganeko, N; Ito, H; Kawakami, Y; Konoike, Y; Miki, Y; Murakami, M; Nagasaki, Y; Suzuki-Yamamoto, T; Takahashi, Y; Tamenobu, A; Toda, K; Tsukayama, I; Yamamoto, K | 1 |
| Lu, RH; Meng, XL; Nie, GX; Qin, CB; Yan, X; Yang, F; Yang, GK; Yang, LP; Zhang, WY; Zhang, YR | 1 |
| Dong, B; Feng, J; Gao, H; Han, S; Li, JX; Li, XX; Tang, M; Wang, QQ; Yang, S; Yuan, R; Zhao, LC | 1 |
| Jiang, C; Lu, G; Ma, X; Wang, R; Yu, S; Yu, Y | 1 |
| Jiang, M; Jiao, JY; Li, Y; Lian, LH; Lin, YC; Liu, J; Nan, JX; Piao, MH; Qiao, CY; Shang, Y; Sun, RH; Wu, YL; Ye, H; Zhan, ZY; Zhang, ZH | 1 |
| Jia, Y; Li, K; Shang, F; Shi, X; Wang, R; Zhang, Y | 1 |
| Chen, L; Huang, T; Lin, T; Wu, L; Yang, B; Yang, J; Zhang, D; Zhang, W; Zhang, Y | 1 |
| Ahmarani, L; Delvin, E; Desjardins, Y; Feldman, F; Koudoufio, M; Levy, E; Spahis, S | 1 |
| Cheng, L; Dong, R; Li, X; Shi, M; Song, C; Yang, Q; Zhang, L; Zhang, Y; Zhao, H | 1 |
| Chen, Y; Feng, N; Feng, Y; Li, S; Ouyang, Y; Wu, Q; Zhang, L; Zhao, K | 1 |
| Andersen-Civil, AIS; Leppä, MM; Salminen, JP; Thamsborg, SM; Williams, AR | 1 |
| Eid, B; El-Shitany, NA | 1 |
| Fan, YX; Gui, X; Han, Y; Hu, L; Jiang, CY; Liu, BQ; Liu, HJ; Liu, WT; Pan, XX; Tang, YL | 1 |
| Hong, J; Liu, R; Liu, W; Ning, G; Shi, J; Sun, Y; Wang, J; Wang, W; Zhao, S | 1 |
| Choi, M; Chung, N; Joo, YH; Kim, Y; Kim, YI; Lee, JW; Min, S; Yim, SV | 1 |
| Feng, GL; Li, F; Li, J; Li, SG; Li, Y; Niu, Q; Song, GL; Wang, C; Wang, HX; Xu, SZ | 1 |
| Chen, Q; Hu, P | 1 |
| Esposito, D; Grace, MH; Komarnytsky, S; Lila, MA; Wang, F; Xiong, J | 1 |
| Balci Yuce, H; Elmastas, M; Gevrek, F; Lektemur Alpan, A; Toker, H | 1 |
| Carmody, RN; Duran, RM; Kalariya, HM; Kuhn, P; Moskal, K; Poulev, A; Raskin, I; Roopchand, DE; Turnbaugh, PJ; Tveter, KM; Zhang, L | 1 |
| Baiyun, R; Jiang, H; Li, D; Li, S; Liu, B; Lu, J; Lv, Y; Qiao, S; Tan, X; Zhang, Z | 1 |
| Castellani, S; Conese, M; Di Gioia, S; di Toma, L; Jirillo, E; Magrone, T; Mandracchia, D; Spagnoletta, A; Trapani, A; Trapani, G | 1 |
| Chen, HX; Liu, J; Qin, DL; Qiu, WQ; Tang, Y; Teng, JF; Wang, XL; Wu, AG; Wu, JM; Xiong, R; Yu, CL; Zhao, Y | 1 |
| Brown, L; John, OD; Mouatt, P; Panchal, SK; Wanyonyi, S | 1 |
| Gao, D; Li, W; Ma, X; Nie, X; Wang, J; Wang, W; Xing, J; Yu, Z; Zhang, X | 1 |
| Cheng, B; Du, J; Hu, T; Jia, Y; Li, K; Peng, J; Wang, Y | 1 |
| Kim, JH; Kim, JM; Kim, M; Lee, MK; Park, KY; Seo, SJ | 1 |
| Aguilera, Y; de Mejia, EG; Martín-Cabrejas, MA; Rebollo-Hernanz, M; Zhang, Q | 1 |
| de Mejia, EG; Fan, J; Johnson, MH; Lila, MA; Yousef, GG | 1 |
| Byun, JK; Cho, ML; Hong, YS; Jhun, JY; Ju, JH; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Park, SH; Yang, EJ; Yoon, BY | 1 |
| Allan, AC; Bovy, A; Butts, CA; Espley, RV; Hedderley, D; Hellens, RP; Laing, WA; Martell, S; McGhie, TK; Paturi, G; Putterill, J; Schouten, HJ; Smith, H; Zhang, J | 1 |
| Abe, K; Deguchi, K; Hishikawa, N; Liu, N; Liu, W; Omote, Y; Yamashita, T; Yunoki, T | 1 |
| Fang, SR; Gu, W; Zhang, Q; Zhou, DY; Zou, CF | 1 |
| Chang, CF; Chen, HB; Guu, SY; Lin, WL; Prakash, E; Tsai, CC; Viswaraman, M | 1 |
| Gao, HQ; Liang, Y; Qiu, J; Wang, J; Wang, QZ; Zhang, J | 1 |
| Celik, S; Günay, E; Günay, S; Hazman, Ö; Özdemir, M; Özyürek, A; Sarinc-Ulasli, S; Ünlü, M | 1 |
| Han, JX; He, JB; Li, P; Long, M; Wang, Y; Yang, SH; Zhang, WK; Zhang, Y | 1 |
| Li, Y; Zhang, Z | 1 |
| Basu, A; Blumberg, JB; Krueger, CG; Lila, MA; Neto, CC; Novotny, JA; Reed, JD; Rodriguez-Mateos, A; Toner, CD | 1 |
| Masumoto, S; Miura, T; Mukai, T; Shoji, T; Terao, A; Yamamoto, Y | 1 |
| Difborg, R; Fryganas, C; Klaver, EJ; Kringel, H; Laan, LC; Mueller-Harvey, I; Ramsay, A; Reed, JD; Skov, S; Thamsborg, SM; van Die, I; Williams, AR | 1 |
| Cho, EJ; Kim, HJ; Yokozawa, T | 1 |
| Bralley, E; Greenspan, P; Hargrove, JL; Hartle, DK | 1 |
| Ardèvol, A; Arola, L; Bladé, C; Blay, M; Bustos, M; Fernández-Larrea, J; Llopiz, N; Montagut, G; Pujadas, G; Salvadó, J; Terra, X | 1 |
| Katiyar, SK; Meeran, SM; Punathil, T; Vaid, M | 1 |
| Ardèvol, A; Arola, L; Bladé, C; Blay, M; Fernández-Larrea, J; Pujadas, G; Salvadó, J; Terra, X | 1 |
| Anke, T; Erkel, G; Jung, M; Richling, E; Triebel, S | 1 |
| Chi, CW; Huang, PL; Liu, TY | 1 |
| Ardèvol, A; Arola, L; Bladé, C; Blay, M; Fernández-Larrea, J; Pallarés, V; Pujadas, G; Salvadó, J; Terra, X | 1 |
| Ho, CT; Lai, CS; Pan, MH; Wu, JC | 1 |
| Ardevol, A; Arola, L; Blade, C; Blay, MT; Fernandez-Larrea, J; Palozza, P; Pujadas, G; Salvado, J; Terra, X | 1 |
| Du, Q; Huang, M; Li, RR; Wei, GZ; Zhang, Q; Zhou, DY | 1 |
| Ge, B; Liu, X; Shi, JC; Wang, XX; Wang, YH; Wu, YJ; Yang, LN; Yang, XL; Zhai, J | 1 |
| Allegra, M; Angileri, F; Gentile, C; Livrea, MA; Pintaudi, AM; Tesoriere, L | 1 |
| Ardèvol, A; Blay, M; González-Abuín, N; Martinez-Micaelo, N; Pinent, M; Richart, C; Terra, X | 1 |
| Arola-Arnal, A; Bladé, C | 1 |
| Kruger, MJ; Smith, C | 1 |
| Li, CM; Xu, SF; Yang, J; Yao, P; Zou, B | 1 |
| Ardévol, A; Arola, L; Blay, M; Calay, D; Castell-Auví, A; Cedó, L; Pallarès, V; Pinent, M; Raes, M | 1 |
| Agackiran, Y; Akyurek, N; Gul, H; Gunay, E; Gunay, S; Ide, T; Memis, L; Sirin, YS | 1 |
| Feldman, M; Grenier, D | 1 |
| Bang, BR; Cho, YS; Kim, TB; Kwon, HS; Lee, KY; Lee, T; Lee, YS; Moon, HB; Moon, KA; Park, MY | 1 |
| Byun, EB; Byun, EH; Byun, MW; Kim, JH; Kim, JK; Lee, JW; Park, JH; Park, SH; Song, BS; Song, DS; Sung, NY | 1 |
| Bagchi, D; Cerinic, MM; Das, DK; Del Rosso, A; Generini, S; Kalin, R; Righi, A | 1 |
| Angenot, L; Damas, J; Garbacki, N; Tits, M | 1 |
| Frederiksen, H; Poulsen, L; Rasmussen, SE; Struntze Krogholm, K | 1 |
| Cho, EJ; Kim, YJ; Lee, YA; Yokozawa, T | 1 |
7 review(s) available for procyanidin and Innate Inflammatory Response
| Article | Year |
|---|---|
Regulatory Roles of Flavonoids on Inflammasome Activation during Inflammatory Responses.
Topics: Animals; Apigenin; Biflavonoids; Catechin; Chalcones; Drug Development; Flavonoids; Humans; Inflammasomes; Inflammation; Luteolin; Proanthocyanidins; Quercetin; Rutin | 2018 |
[Research progress on the effects of proanthochanidins in reshaping microbiota and suppressing inflammation].
Topics: Anti-Bacterial Agents; Female; Humans; Inflammation; Microbiota; Proanthocyanidins | 2023 |
Grape Seeds Proanthocyanidins: An Overview of In Vivo Bioactivity in Animal Models.
Topics: Animals; Inflammation; Metabolic Syndrome; Oxidative Stress; Proanthocyanidins; Seeds; Vitis | 2019 |
Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction.
Topics: Animals; Humans; Inflammation; Inflammatory Bowel Diseases; Obesity; Phytochemicals; Proanthocyanidins | 2020 |
Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015.
Topics: Animals; Anti-Infective Agents; Biofilms; Diet; Fruit; Gastrointestinal Microbiome; Health Promotion; Heart Diseases; Humans; Inflammation; Lipids; Metabolic Diseases; Oxidative Stress; Phytochemicals; Plant Extracts; Proanthocyanidins; Risk Factors; Vaccinium macrocarpon | 2016 |
Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds.
Topics: Anticarcinogenic Agents; Apoptosis; Carotenoids; Cell Differentiation; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Diet; Fatty Acids, Omega-3; Flavonoids; Humans; Inflammation; Life Style; Proanthocyanidins; Signal Transduction; Sphingolipids | 2011 |
Dietary proanthocyanidins: occurrence, dietary intake, bioavailability, and protection against cardiovascular disease.
Topics: Animals; Arteriosclerosis; Biological Availability; Cardiovascular Diseases; Diet; Disease Models, Animal; Endothelium, Vascular; Humans; Inflammation; Lipid Peroxidation; Lipoproteins, LDL; Pinus; Platelet Aggregation; Proanthocyanidins | 2005 |
85 other study(ies) available for procyanidin and Innate Inflammatory Response
| Article | Year |
|---|---|
Cocoa procyanidins modulate transcriptional pathways linked to inflammation and metabolism in human dendritic cells.
Topics: Adenylyl Cyclases; Biflavonoids; Cacao; Catechin; Chemokines; Dendritic Cells; Gene Expression Profiling; Humans; Inflammation; Plant Extracts; Proanthocyanidins; Soluble Guanylyl Cyclase; Transcription, Genetic | 2018 |
Grape seed procyanidin extract reduces the endotoxic effects induced by lipopolysaccharide in rats.
Topics: Animals; Biflavonoids; Catechin; Grape Seed Extract; Inflammation; Interleukins; Lipopolysaccharides; Nitric Oxide; Oxidative Stress; Proanthocyanidins; Rats; Reactive Oxygen Species; Shock, Septic; Tumor Necrosis Factor-alpha | 2013 |
Prevention of oxidative stress, inflammation and mitochondrial dysfunction in the intestine by different cranberry phenolic fractions.
Topics: Adenosine Triphosphate; Antioxidants; Apoptosis; Biflavonoids; Caco-2 Cells; Catechin; Dinoprostone; Fatty Acids; Humans; Inflammation; Intestines; Lipid Peroxidation; Mitochondria; Oxidative Phosphorylation; Oxidative Stress; Plant Extracts; Proanthocyanidins; Vaccinium macrocarpon | 2015 |
Grape seed procyanidin supplementation to rats fed a high-fat diet during pregnancy and lactation increases the body fat content and modulates the inflammatory response and the adipose tissue metabolism of the male offspring in youth.
Topics: Adipose Tissue; Animals; Animals, Newborn; Antioxidants; Biflavonoids; Body Weight; Catechin; Diet, High-Fat; Female; Grape Seed Extract; Inflammation; Lactation; Lipid Metabolism; Male; Plant Extracts; Pregnancy; Proanthocyanidins; Rats | 2015 |
Cocoa procyanidins with different degrees of polymerization possess distinct activities in models of colonic inflammation.
Topics: Anti-Inflammatory Agents; Biflavonoids; Cacao; Caco-2 Cells; Catechin; Chromatography, High Pressure Liquid; Colon; HT29 Cells; Humans; Inflammation; Interleukin-8; Molecular Weight; Permeability; Plant Extracts; Proanthocyanidins | 2015 |
Insights into the leaves of Ceriscoides campanulata: Natural proanthocyanidins alleviate diabetes, inflammation, and esophageal squamous cell cancer via in vitro and in silico models.
Topics: Acetylcholinesterase; alpha-Amylases; alpha-Glucosidases; Animals; Butyrylcholinesterase; Carcinoma, Squamous Cell; Computer Simulation; Diabetes Mellitus; Epithelial Cells; Esophageal Neoplasms; Glycoside Hydrolase Inhibitors; Humans; Inflammation; Mammals; Molecular Docking Simulation; Molecular Structure; Plant Leaves; Proanthocyanidins; Rubiaceae | 2022 |
Dietary proanthocyanidins promote localized antioxidant responses in porcine pulmonary and gastrointestinal tissues during Ascaris suum-induced type 2 inflammation.
Topics: Animals; Antioxidants; Ascaris suum; Colon; Diet; Inflammation; Lung; Proanthocyanidins; Swine | 2022 |
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Topics: Animals; Diabetes, Gestational; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Inflammasomes; Inflammation; Insulin; Insulin Resistance; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pregnancy; Proanthocyanidins | 2022 |
Procyanidins from hawthorn (
Topics: Animals; Crataegus; Diet, High-Fat; Gastrointestinal Microbiome; Humans; Inflammation; Insulin Resistance; Lipid Metabolism; Lipid Metabolism Disorders; Lipids; Mice; Mice, Inbred C57BL; Oxidative Stress; Proanthocyanidins; Rats | 2022 |
Effect and mechanism of peanut skin proanthocyanidins on gliadin-induced Caco-2 celiac disease model cells.
Topics: Arachis; Caco-2 Cells; Celiac Disease; Gliadin; Humans; Inflammation; NF-kappa B; Proanthocyanidins; Sirtuin 1 | 2022 |
The protective effect of proanthocyanidins on the psoriasis-like cell models via PI3K/AKT and HO-1.
Topics: Animals; Antioxidants; Heme Oxygenase-1; Inflammation; Mice; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Psoriasis; Signal Transduction; Tumor Necrosis Factor-alpha | 2022 |
Proanthocyanidins attenuates ferroptosis against influenza-induced acute lung injury in mice by reducing IFN-γ.
Topics: Acute Lung Injury; Animals; Ferroptosis; Humans; Inflammation; Influenza A virus; Influenza, Human; Interferon-gamma; Mice; Proanthocyanidins; Transforming Growth Factor beta1 | 2023 |
Highly efficient photothermal branched Au-Ag nanoparticles containing procyanidins for synergistic antibacterial and anti-inflammatory immunotherapy.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacteria; Gold; Immunotherapy; Inflammation; Metal Nanoparticles; Nanoparticles; Phototherapy; Proanthocyanidins; Reactive Oxygen Species; Silver | 2023 |
Anti-Inflammatory, Anti-Bacterial, and Anti-Fungal Activity of Oligomeric Proanthocyanidins and Extracts Obtained from Lignocellulosic Agricultural Waste.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Ethanol; Humans; Inflammation; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Plant Extracts; Proanthocyanidins; Water | 2023 |
Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota.
Topics: Animals; Antioxidants; Cadmium; Cytokines; Female; Gastrointestinal Microbiome; Humans; Inflammation; Oxidative Stress; Proanthocyanidins; Rats; Superoxide Dismutase; Uterus | 2023 |
Protective Effects of Proanthocyanidin-Rich Fraction from Red Rice Germ and Bran on Lung Cell Inflammation via Inhibition of NF-κB/NLRP3 Inflammasome Pathway.
Topics: Adenosine Triphosphate; Functional Food; Inflammasomes; Inflammation; Interleukin-18; Interleukin-6; Lipopolysaccharides; Lung; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oryza; Plant Extracts; Pneumonia; Proanthocyanidins | 2023 |
The effects of Vitis vinifera L. phenolic compounds on a blood-brain barrier culture model: Expression of leptin receptors and protection against cytokine-induced damage.
Topics: Animals; Animals, Newborn; Astrocytes; Blood-Brain Barrier; Catechin; Cells, Cultured; Cytokines; Drug Evaluation, Preclinical; Endothelial Cells; Endothelium, Vascular; Ethnopharmacology; Gallic Acid; Grape Seed Extract; Humans; Inflammation; Leptin; Medicine, Ayurvedic; Primary Cell Culture; Proanthocyanidins; Rats; Reactive Oxygen Species; Receptors, Leptin; Resveratrol; Vitis | 2020 |
Procyanidin B2 Suppresses Lipopolysaccharides-Induced Inflammation and Apoptosis in Human Type II Alveolar Epithelial Cells and Lung Fibroblasts.
Topics: Alveolar Epithelial Cells; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biflavonoids; Catechin; Cell Proliferation; Cells, Cultured; Cytokines; Fibroblasts; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; Lung; Proanthocyanidins | 2020 |
Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells.
Topics: Animals; Catechin; Cell Nucleus; Cytokines; Heme Oxygenase-1; Inflammation; Inflammation Mediators; Lipopolysaccharides; Membrane Potential, Mitochondrial; Mice; Mitogen-Activated Protein Kinases; Models, Biological; NF-E2-Related Factor 2; NF-kappa B; Proanthocyanidins; Protein Transport; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptors | 2019 |
Grape seed procyanidin suppresses inflammation in cigarette smoke-exposed pulmonary arterial hypertension rats by the PPAR-γ/COX-2 pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cells, Cultured; Cigarette Smoking; Cyclooxygenase 2; Disease Models, Animal; Grape Seed Extract; Inflammation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Proanthocyanidins; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling | 2020 |
Proanthocyanidins Promote Osteogenic Differentiation of Human Periodontal Ligament Fibroblasts in Inflammatory Environment Via Suppressing NF-κB Signal Pathway.
Topics: Adolescent; Cell Differentiation; Cells, Cultured; Female; Fibroblasts; Humans; Inflammation; Inflammation Mediators; Male; NF-kappa B; Osteogenesis; Periodontal Ligament; Proanthocyanidins; Signal Transduction; Young Adult | 2020 |
Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Inflammation; Lipoxygenase Inhibitors; Male; Mice, Inbred BALB C; Oryza; Proanthocyanidins; Psoriasis; Rats | 2020 |
Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulation and inflammation in grass carp (Ctenopharyngodon idella).
Topics: Animals; Carps; Grape Seed Extract; Hepatocytes; Inflammation; Lipid Metabolism; Liver; Oleic Acid; Plant Extracts; Proanthocyanidins | 2020 |
Procyanidin A2, a polyphenolic compound, exerts anti-inflammatory and anti-oxidative activity in lipopolysaccharide-stimulated RAW264.7 cells.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Catechin; Cytokines; Dinoprostone; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Proanthocyanidins; RAW 264.7 Cells; Signal Transduction | 2020 |
Anti-Inflammatory Activity of Oligomeric Proanthocyanidins Via Inhibition of NF-κB and MAPK in LPS-Stimulated MAC-T Cells.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cattle; Cell Survival; Cyclooxygenase 2; Epithelial Cells; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; MAP Kinase Signaling System; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Proanthocyanidins; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2020 |
Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages.
Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Cathepsin B; Cytokines; Dinoprostone; Gout; Inflammasomes; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; NLR Family, Pyrin Domain-Containing 3 Protein; Proanthocyanidins; Uric Acid | 2020 |
Persimmon oligomeric proanthocyanidins alleviate ultraviolet B-induced skin damage by regulating oxidative stress and inflammatory responses.
Topics: Animals; Apoptosis; Female; Humans; Inflammation; Mice; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species; Skin; Ultraviolet Rays | 2020 |
Attenuation of Perfluorooctane Sulfonate-Induced Steatohepatitis by Grape Seed Proanthocyanidin Extract in Mice.
Topics: Alkanesulfonic Acids; Animals; CD36 Antigens; Cholesterol; Fatty Acid-Binding Proteins; Fatty Liver; Fluorocarbons; Hydrogen Peroxide; Inflammation; Interleukin-6; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Proanthocyanidins; Triglycerides; Tumor Necrosis Factor-alpha | 2020 |
Intestinal protection by proanthocyanidins involves anti-oxidative and anti-inflammatory actions in association with an improvement of insulin sensitivity, lipid and glucose homeostasis.
Topics: Caco-2 Cells; Carbohydrate Metabolism; Drug Evaluation, Preclinical; Humans; Inflammation; Insulin Resistance; Intestines; Lipid Metabolism; Oxidative Stress; Proanthocyanidins | 2021 |
Combination of tea polyphenols and proanthocyanidins prevents menopause-related memory decline in rats via increased hippocampal synaptic plasticity by inhibiting p38 MAPK and TNF-α pathway.
Topics: Animals; Female; Hippocampus; Inflammation; Long-Term Potentiation; Memory Disorders; Menopause; Neuronal Plasticity; p38 Mitogen-Activated Protein Kinases; Polyphenols; Proanthocyanidins; Rats; Receptors, Tumor Necrosis Factor, Type I; Tea; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha | 2022 |
Effect of lotus seedpod oligomeric procyanidins on AGEs formation in simulated gastrointestinal tract and cytotoxicity in Caco-2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Catechin; Colonic Neoplasms; Digestion; Gastrointestinal Tract; Gene Expression; Glycation End Products, Advanced; Humans; Inflammation; Nelumbo; Pepsin A; Proanthocyanidins; Reactive Oxygen Species; Seeds; Tocopherols; Trypsin Inhibitors | 2021 |
Structure-function analysis of purified proanthocyanidins reveals a role for polymer size in suppressing inflammatory responses.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Inflammation; Macrophages; Mice; Plant Extracts; Proanthocyanidins; RAW 264.7 Cells | 2021 |
Proanthocyanidin protects against cisplatin-induced oxidative liver damage through inhibition of inflammation and NF-κβ/TLR-4 pathway.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Cisplatin; Cyclooxygenase 2; Cytokines; Inflammation; Liver; Male; NF-kappa B; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proanthocyanidins; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression.
Topics: Animals; Ankle; Anti-Inflammatory Agents; Antioxidants; Colchicine; Cytokines; Gout; Grape Seed Extract; Inflammation; Lipopolysaccharides; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; p38 Mitogen-Activated Protein Kinases; Pain; Phosphorylation; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction; Spinal Cord; Uric Acid | 2017 |
Grape seed proanthocyanidin extract ameliorates inflammation and adiposity by modulating gut microbiota in high-fat diet mice.
Topics: Adiposity; Animals; Diet, High-Fat; Gastrointestinal Microbiome; Grape Seed Extract; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Proanthocyanidins; Tumor Necrosis Factor-alpha | 2017 |
Grape seed proanthocyanidin inhibits inflammatory responses in hepatic stellate cells by modulating the MAPK, Akt and NF-κB signaling pathways.
Topics: Cell Line, Transformed; Cytokines; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hepatic Stellate Cells; Humans; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; NF-kappa B; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Seeds; Vitis | 2017 |
Grape Seed Procyanidin Extract Reduces Arsenic-Induced Renal Inflammatory Injury in Male Mice.
Topics: Animals; Arsenic; Grape Seed Extract; Inflammation; Kidney Diseases; Male; Mice; Proanthocyanidins | 2017 |
Proanthocyanidins prevent ethanol-induced cognitive impairment by suppressing oxidative and inflammatory stress in adult rat brain.
Topics: Alcoholism; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain; Central Nervous System Depressants; Cognitive Dysfunction; Cytokines; Dose-Response Relationship, Drug; Ethanol; Inflammation; Male; Maze Learning; Nootropic Agents; Oxidative Stress; Proanthocyanidins; Random Allocation; Rats, Sprague-Dawley | 2017 |
Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities.
Topics: Acacia; alpha-Amylases; alpha-Glucosidases; Animals; Anti-Inflammatory Agents; Carbohydrate Metabolism; Glycoside Hydrolase Inhibitors; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Bark; Plant Extracts; Polyphenols; Proanthocyanidins; RAW 264.7 Cells | 2017 |
Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Grape Seed Extract; Hypoxia-Inducible Factor 1; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Ligation; Male; Matrix Metalloproteinase 8; Osteoblasts; Osteoclasts; Periodontitis; Proanthocyanidins; Rats; Rats, Wistar; Streptozocin; Tartrate-Resistant Acid Phosphatase; Vascular Endothelial Growth Factor A | 2018 |
Grape proanthocyanidin-induced intestinal bloom of Akkermansia muciniphila is dependent on its baseline abundance and precedes activation of host genes related to metabolic health.
Topics: Animal Feed; Animals; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Gastrointestinal Microbiome; Glucose Tolerance Test; Inflammation; Intestines; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Plant Extracts; Polyphenols; Proanthocyanidins; RNA, Ribosomal, 16S; Soybean Proteins; Verrucomicrobia; Vitis | 2018 |
Grape seed procyanidin extract protects against Pb-induced lung toxicity by activating the AMPK/Nrf2/p62 signaling axis.
Topics: Adenylate Kinase; Animals; Apoptosis; Enzyme Activation; Gene Silencing; Grape Seed Extract; Heme Oxygenase (Decyclizing); Inflammation; Lead; Lung; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Rats, Wistar; Sequestosome-1 Protein; Signal Transduction | 2018 |
Nanoparticle delivery of grape seed-derived proanthocyanidins to airway epithelial cells dampens oxidative stress and inflammation.
Topics: Animals; Apoptosis; Biocompatible Materials; Cell Line, Tumor; Endocytosis; Epithelial Cells; Grape Seed Extract; Hydrogen Peroxide; Inflammation; Lung; Male; Mice, Inbred C57BL; Nanoparticles; Necrosis; NF-kappa B; Oxidative Stress; Particle Size; Proanthocyanidins; Protein Transport | 2018 |
Polyphenols Derived from Lychee Seed Suppress Aβ (1-42)-Induced Neuroinflammation.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Catechin; Cell Line; Inflammation; Interleukin-1beta; Interleukin-6; Litchi; Mice; Neurons; NF-kappa B; Polyphenols; Proanthocyanidins; Seeds; Tumor Necrosis Factor-alpha | 2018 |
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Topics: Animals; Blood Pressure; Cardiovascular Diseases; Citric Acid; Collagen; Diet; Dietary Supplements; Fruit; Garcinia; Heart Ventricles; Inflammation; Male; Metabolic Syndrome; Phytotherapy; Plant Epidermis; Plant Extracts; Proanthocyanidins; Rats, Wistar; Vascular Stiffness | 2018 |
Epicatechin alleviates inflammation in lipopolysaccharide-induced acute lung injury in mice by inhibiting the p38 MAPK signaling pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Proanthocyanidins; Protein Binding | 2019 |
GC-(4→8)-GCG, A Proanthocyanidin Dimer from Camellia ptilophylla, Modulates Obesity and Adipose Tissue Inflammation in High-Fat Diet Induced Obese Mice.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Camellia; Diet, High-Fat; Dimerization; Fatty Liver; Inflammation; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Obesity; Proanthocyanidins | 2019 |
Afzelin suppresses proinflammatory responses in particulate matter-exposed human keratinocytes.
Topics: Anti-Inflammatory Agents; Cell Line; Cell Survival; Cytokines; Humans; Inflammation; Keratinocytes; Mannosides; Particulate Matter; Proanthocyanidins; Reactive Oxygen Species | 2019 |
Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation between Macrophages and Adipocytes In Vitro.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biflavonoids; Cacao; Catechin; Glucose Transporter Type 4; Hydroxybenzoates; Inflammation; Insulin Resistance; Lipid Metabolism; Macrophages; Mice; Mitochondria; Phenols; Plant Extracts; Proanthocyanidins; RAW 264.7 Cells | 2019 |
Anthocyanins and proanthocyanidins from blueberry-blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate-utilizing enzymes in vitro.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Anthocyanins; Antioxidants; Beverages; Blueberry Plants; Cell Line, Tumor; Cell Proliferation; Fermentation; Fruit; Glucosides; Inflammation; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Plant Extracts; Polyphenols; Proanthocyanidins; Wine | 2013 |
Grape seed proanthocyanidin extract-mediated regulation of STAT3 proteins contributes to Treg differentiation and attenuates inflammation in a murine model of obesity-associated arthritis.
Topics: Administration, Oral; Animals; Arthritis; Arthritis, Experimental; Cell Differentiation; Cytokines; Diet, High-Fat; Disease Models, Animal; Gene Expression; Grape Seed Extract; Humans; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; Microscopy, Confocal; Obesity; Proanthocyanidins; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2013 |
Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice.
Topics: Animals; Anthocyanins; Bacteria; Biflavonoids; Biomarkers; Catechin; Colon; Diet; Dietary Supplements; Flavonoids; Food, Genetically Modified; Fruit; Genotype; Glycosides; Inflammation; Inflammation Mediators; Male; Malus; Mice; Mice, Inbred Strains; Microbiota; Phytotherapy; Plant Extracts; Plants, Genetically Modified; Proanthocyanidins; Quercetin; Reference Values; Transcription Factors; Transcription, Genetic; Transformation, Genetic | 2014 |
Anti-oxidative nutrient-rich diet protects against acute ischemic brain damage in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehydes; Animals; Antioxidants; Biomarkers; Brain Chemistry; Brain Damage, Chronic; Brain Ischemia; Cerebral Infarction; Deoxyguanosine; Diet; Glycation End Products, Advanced; Infarction, Middle Cerebral Artery; Inflammation; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar | 2014 |
Proanthocyanidin from grape seed extract inhibits airway inflammation and remodeling in a murine model of chronic asthma.
Topics: Actins; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Female; Grape Seed Extract; Hydroxyproline; Immunoglobulin E; Inflammation; Mice; Mice, Inbred BALB C; Ovalbumin; Proanthocyanidins; Transforming Growth Factor beta1 | 2015 |
Derivation of Cinnamon Blocks Leukocyte Attachment by Interacting with Sialosides.
Topics: Agglutination; Anti-Inflammatory Agents; Cell Adhesion; Cell Line, Tumor; Cinnamomum zeylanicum; Drugs, Chinese Herbal; E-Selectin; Endothelium, Vascular; Erythrocyte Aggregation; Erythrocytes; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; N-Acetylneuraminic Acid; Neutrophils; Orthomyxoviridae; Proanthocyanidins; Protein Binding; Tumor Necrosis Factor-alpha | 2015 |
Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells.
Topics: Angiotensin II; Animals; Antioxidants; Chemokine CCL2; Cofilin 1; Creatinine; Cytoskeleton; Epithelial Cells; Gene Expression Regulation; Grape Seed Extract; Humans; Hypertension; Inflammation; Interleukin-1beta; Kidney Tubules; Male; NF-kappa B p50 Subunit; Nitrogen; Proanthocyanidins; Rats; Rats, Inbred SHR; Renal Insufficiency; RNA, Small Interfering; Urea | 2015 |
Comparison of the Anti-inflammatory Effects of Proanthocyanidin, Quercetin, and Damnacanthal on Benzo(a)pyrene Exposed A549 Alveolar Cell Line.
Topics: A549 Cells; Alveolar Epithelial Cells; Anthraquinones; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzo(a)pyrene; Cell Line, Tumor; Cell Survival; Cytokines; Glutathione; Humans; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-1beta; Malondialdehyde; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proanthocyanidins; Quercetin; Tumor Necrosis Factor-alpha | 2016 |
Intervention of Grape Seed Proanthocyanidin Extract on the Subchronic Immune Injury in Mice Induced by Aflatoxin B1.
Topics: Aflatoxin B1; Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Grape Seed Extract; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Inflammation; Male; Mice; Proanthocyanidins; Spleen | 2016 |
Grape seed proanthocyanidin extracts prevent hyperglycemia-induced monocyte adhesion to aortic endothelial cells and ameliorates vascular inflammation in high-carbohydrate/high-fat diet and streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Carotid Intima-Media Thickness; Cell Adhesion; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Carbohydrates; Endothelial Cells; Glycation End Products, Advanced; Grape Seed Extract; Hyperglycemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Monocytes; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Streptozocin; Vascular Cell Adhesion Molecule-1 | 2015 |
Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes.
Topics: Animals; Bacteroidetes; Cecum; Diet, High-Fat; Dietary Sugars; Firmicutes; Gastrointestinal Microbiome; Homeostasis; Inflammation; Insulin Resistance; Lipopolysaccharides; Male; Malus; Metabolome; Metabolomics; Mice, Inbred C57BL; Obesity; Permeability; Proanthocyanidins; RNA, Ribosomal, 16S; Weight Gain | 2016 |
Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode Trichuris suis.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Helminth; Cells, Cultured; Cytokines; Dendritic Cells; Drug Therapy, Combination; Humans; Inflammation; Lymphocyte Activation; OX40 Ligand; Proanthocyanidins; RNA Interference; Swine; Th1 Cells; Th1-Th2 Balance; Th2 Cells; Trichuriasis; Trichuris; Up-Regulation | 2017 |
Gravinol ameliorates high-fructose-induced metabolic syndrome through regulation of lipid metabolism and proinflammatory state in rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Cytokines; Fructose; Grape Seed Extract; Inflammation; Lipid Metabolism; Liver; Male; Metabolic Diseases; Plant Extracts; PPAR alpha; Proanthocyanidins; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2 | 2008 |
Inhibition of hyaluronidase activity by select sorghum brans.
Topics: Anthocyanins; Dietary Fiber; Enzyme Inhibitors; Ferric Compounds; Flavonoids; Hyaluronoglucosaminidase; Inflammation; Oryza; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Sorghum | 2008 |
Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet.
Topics: Adiponectin; Adipose Tissue; Animals; C-Reactive Protein; Cytokines; Dietary Fats; Glutathione; Inflammation; Interleukin-6; Liver; Male; Proanthocyanidins; Rats; Rats, Zucker; Vitis | 2009 |
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Inhibitory effects of grape seed procyanidins on foam cell formation in vitro.
Topics: Animals; Cell Line; Cholesterol; Foam Cells; Gene Expression; Inflammation; Lipoproteins, LDL; Macrophages; Mice; Proanthocyanidins; Seeds; Triglycerides; Vitis | 2009 |
Influence of apple polyphenols on inflammatory gene expression.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biflavonoids; Catechin; Cell Line, Tumor; Cytokines; Flavonoids; Fruit; Gene Expression; Genes, Reporter; Humans; Inflammation; Inhibitory Concentration 50; Jurkat Cells; Malus; Oligonucleotide Array Sequence Analysis; Phenols; Phloretin; Plant Extracts; Polyphenols; Proanthocyanidins; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Effects of Areca catechu L. containing procyanidins on cyclooxygenase-2 expression in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Areca; Blotting, Western; Carrageenan; Cell Line, Tumor; Chromans; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Male; Nuts; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds | 2010 |
Modulatory effect of grape-seed procyanidins on local and systemic inflammation in diet-induced obesity rats.
Topics: Adipose Tissue, White; Animals; C-Reactive Protein; Dietary Fats; Female; Inflammation; Interleukin-6; NF-kappa B; Obesity; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Receptors, Cell Surface; Seeds; Tumor Necrosis Factor-alpha; Vitis | 2011 |
Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes.
Topics: Antioxidants; Biflavonoids; Catechin; Cell Line; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radicals; Humans; I-kappa B Kinase; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Monocytes; NF-kappa B; Phosphorylation; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction | 2011 |
Grape seed proanthocyanidin extract attenuates airway inflammation and hyperresponsiveness in a murine model of asthma by downregulating inducible nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Grape Seed Extract; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-13; Interleukin-4; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred BALB C; Neutrophils; Nitric Oxide Synthase Type II; Ovalbumin; Proanthocyanidins; Random Allocation; Vitis | 2011 |
Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis.
Topics: Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Humans; Immunomodulation; Inflammation; Male; NF-kappa B; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Recurrence; Seeds; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Vitis | 2011 |
Polymeric proanthocyanidins from Sicilian pistachio (Pistacia vera L.) nut extract inhibit lipopolysaccharide-induced inflammatory response in RAW 264.7 cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Cyclooxygenase 2; Inflammation; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nuts; Pistacia; Plant Extracts; Proanthocyanidins; Tumor Necrosis Factor-alpha | 2012 |
Omega-3 docosahexaenoic acid and procyanidins inhibit cyclo-oxygenase activity and attenuate NF-κB activation through a p105/p50 regulatory mechanism in macrophage inflammation.
Topics: Biflavonoids; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Docosahexaenoic Acids; Fatty Acids, Omega-3; Humans; I-kappa B Proteins; Inflammation; Interleukin-6; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Proanthocyanidins; Transcription Factor RelA | 2012 |
Proanthocyanidins modulate microRNA expression in human HepG2 cells.
Topics: Catechin; Computational Biology; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Insulin; Lipid Metabolism; MicroRNAs; Oxidative Stress; Proanthocyanidins; Reproducibility of Results; Signal Transduction; Transcriptome | 2011 |
Postcontusion polyphenol treatment alters inflammation and muscle regeneration.
Topics: Analysis of Variance; Animals; Blotting, Western; Case-Control Studies; Contusions; Image Processing, Computer-Assisted; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Polyphenols; Proanthocyanidins; Random Allocation; Rats; Rats, Wistar | 2012 |
Characterization of a highly polymeric proanthocyanidin fraction from persimmon pulp with strong Chinese cobra PLA2 inhibition effects.
Topics: Animals; Anti-Inflammatory Agents; Diospyros; Elapidae; Female; Fruit; Inflammation; Male; Mice; Molecular Structure; Phospholipase A2 Inhibitors; Plant Exudates; Polymers; Proanthocyanidins; Rats; Reptilian Proteins; Snake Venoms | 2012 |
Additive, antagonistic, and synergistic effects of procyanidins and polyunsaturated fatty acids over inflammation in RAW 264.7 macrophages activated by lipopolysaccharide.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dietary Fats; Drug Interactions; Eicosapentaenoic Acid; Gene Expression Regulation; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phytotherapy; Plant Extracts; Proanthocyanidins | 2012 |
The efficiency of proanthocyanidin in an experimental pulmonary fibrosis model: comparison with taurine.
Topics: Animals; Antioxidants; Bleomycin; Grape Seed Extract; Hydroxyproline; Inflammation; Lung; Lymphocytes; Macrophages; Male; Neutrophils; Nitric Oxide Synthase Type II; Proanthocyanidins; Pulmonary Fibrosis; Rats; Rats, Wistar; Taurine | 2012 |
Cranberry proanthocyanidins act in synergy with licochalcone A to reduce Porphyromonas gingivalis growth and virulence properties, and to suppress cytokine secretion by macrophages.
Topics: Biofilms; Cell Line; Chalcones; Epithelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Microbial Collagenase; Plant Extracts; Porphyromonas gingivalis; Proanthocyanidins; Tumor Necrosis Factor-alpha; Vaccinium macrocarpon; Virulence | 2012 |
Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chronic Disease; Disease Models, Animal; Female; Fibrosis; Gene Expression; Glutathione; Grape Seed Extract; Inflammation; Interleukin-13; Interleukin-4; Interleukin-5; Leukocytes, Mononuclear; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Proanthocyanidins | 2012 |
The procyanidin trimer C1 inhibits LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Biflavonoids; Catechin; Cell Line; Cyclooxygenase 2; Dinoprostone; Inflammation; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; NF-kappa B; Nitric Oxide; Proanthocyanidins; Toll-Like Receptor 4 | 2013 |
Activin, a grape seed-derived proanthocyanidin extract, reduces plasma levels of oxidative stress and adhesion molecules (ICAM-1, VCAM-1 and E-selectin) in systemic sclerosis.
Topics: Activins; Anthocyanins; Cell Adhesion; E-Selectin; Humans; Inflammation; Intercellular Adhesion Molecule-1; Malondialdehyde; Models, Chemical; Oxidative Stress; Pilot Projects; Plant Extracts; Proanthocyanidins; Scleroderma, Systemic; Seeds; Vascular Cell Adhesion Molecule-1; Vitis | 2002 |
Inhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats.
Topics: Animals; Carrageenan; Cytokines; Disease Models, Animal; Edema; Inflammation; Male; Nitrates; Nitrites; Plant Leaves; Pleurisy; Proanthocyanidins; Rats; Rats, Wistar; Ribes | 2004 |
Ameliorative effects of proanthocyanidin on oxidative stress and inflammation in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diospyros; Fruit; Glutathione; Inflammation; Kidney; Lipid Peroxidation; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar | 2007 |