procyanidin has been researched along with Disease Models, Animal in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 25 (19.53) | 29.6817 |
| 2010's | 81 (63.28) | 24.3611 |
| 2020's | 22 (17.19) | 2.80 |
| Authors | Studies |
|---|---|
| Bergamo, P; Bessa-Pereira, C; Dias, R; Freitas, V; Luongo, D; Maurano, F; Mazzarella, G; Pérez-Gregorio, M; Rossi, M; Rotondi Aufiero, V | 1 |
| Inagaki, Y; Kato, E; Kawabata, J; Kurokawa, M; Kushibiki, N | 1 |
| Liu, D | 1 |
| Bai, S; Du, F; Fu, X; Jiao, Y; Ma, J; Wang, L; Zhou, L | 1 |
| Bobinski, F; Buffon, LD; da Silva, GS; da Silva, TBGC; David, IMB; de Souza Fernandes, F; Dos Santos Silva Ferreira, JB; Kopper, MBR; Kviecinski, MR; Lüdtke, DD; Martins, DF; Pedrosa, RC; Zeferino, RC | 1 |
| Liu, CX; Min, LQ; Song, CG; Yang, X; Zhao, CS | 1 |
| Aswar, UM; Kandhare, AD; Mohan, V; Thakurdesai, PA | 1 |
| Ashida, H; Ito, C; Nanba, F; Toda, T; Wang, L; Yamashita, Y | 1 |
| Abadie, J; Beck, L; Gauthier, O; Guicheux, J; Hivernaud, V; Houard, X; Krisa, S; Lesoeur, J; Masson, M; Merceron, C; Mével, E; Nourissat, G; Richard, T; Urban, N; Vinatier, C; Wittrant, Y | 1 |
| Cobelli, NJ; Hardin, JA; He, Z; Hirsh, DM; Kim, SJ; Leong, DJ; Liu, L; Sun, HB; Wang, A; Xu, L | 1 |
| Fumoto, T; Imaizumi, T; Masumoto, S; Matsuda, N; Miura, T; Naraoka, M; Ohkuma, H; Shoji, T; Wang, L | 1 |
| Chen, K; Chen, L; Jia, Q; Li, Y; Sun, P; Wang, H; Wang, T | 1 |
| Cheng, CH; Kong, LD; Wang, Y; Yang, C; Zhang, X; Zhu, JX | 1 |
| Ardévol, A; Arola, L; Bladé, MC; Blay, M; Pinent, M; Salvadó, MJ | 1 |
| Kong, X; Sheng, K; Wang, J; Wang, Y; Xu, Y; Yang, J | 1 |
| Chen, S; Pan, H; Ye, X; Zhang, Y | 1 |
| Chen, Y; Gu, B; Liu, Z; Mao, Z; Qian, Y; Shi, Y; Sun, Y; Wu, D; Zhang, Q | 1 |
| Chen, H; Deng, G; Li, Y; Lin, X; Liu, Y; Shen, S; Sun, R; Wei, Y; Wu, L | 1 |
| Guo, M; Lai, R; Lei, Q; Xian, D; Xian, L; Xu, J; Yang, Y; Zhao, Y; Zhong, J | 1 |
| Chen, W; Fan, C; Li, X; Pi, X; Ren, X; Rong, S; Wang, T; Wang, Z; Xu, Y; Zhang, Y; Zhao, S | 1 |
| Li, S; Liu, C; Shi, Y; Wang, S; Xin, D; Yan, B; Zhang, H | 1 |
| Becker, MW; Bezerra, DP; Bystrom, LM; Cunningham-Rundles, S; De Leon, JP; Emmanuel, M; Gardenghi, S; Guzman, ML; Hassane, D; Hsu, HT; Lara-Martínez, LA; Méry, D; Neto, CC; Rivella, S; Zong, H | 1 |
| Hu, S; Liu, J; Shao, S; Yuan, L; Zhu, B | 1 |
| Liang, X; Liu, Y; Wang, K; Wei, H; Xu, G; Zhan, J; Zhang, C | 1 |
| Boutkrabt, L; Daoust, L; Desjardins, Y; Dudonné, S; Levy, É; Marette, A; Pilon, G; Rodríguez-Daza, MC; Roy, D; Varin, T | 1 |
| Hu, Y; Hu, Z; Huang, S; Liu, H; Shang, P; Tang, Q; Zhu, J | 1 |
| Dun, XP; Gao, WL; Jing, XK; Li, XH; Li, YK; Yang, K | 1 |
| Du, X; Fu, X; Hou, Y; Huang, Z; Li, J; Luo, Y; Zhuan, Q | 1 |
| Liu, HF; Liu, JX; Liu, ZJ; Pan, Q; Su, HY; Yang, C; Zhang, WH | 1 |
| Arola-Arnal, A; Bravo, FI; Iglesias-Carres, L; Mas-Capdevila, A; Muguerza, B; Suárez, M | 1 |
| Geng, X; Li, L; Tian, L; Wang, D; Wang, Q | 1 |
| Crescenti, A; Gibert-Ramos, A; Martín-González, MZ; Salvadó, MJ | 1 |
| Hadzik, J; Kubasiewicz-Ross, P; Matkowski, A; Nawrot-Hadzik, I | 1 |
| Choi, CW; Choi, YH; Hwang, H; Jang, MJ; Kim, MS; Lee, B; Oh, SY; Rhim, H | 1 |
| Guo, J; Ji, H; Li, C; Li, S; Lian, S; Liu, Y; Lu, J; Lv, H; Ma, L; Xu, B; Yang, H | 1 |
| Ardévol, A; Beltrán-Debón, R; Blay, M; Grau-Bové, C; Miguéns-Gómez, A; Pinent, M; Rodríguez-Gallego, E; Sierra-Cruz, M; Terra, X | 1 |
| Arola, L; Arola-Arnal, A; Bladé, C; Bravo, FI; Pascual-Serrano, A; Suárez, M; Suárez-García, S | 1 |
| Abdelhalim, SZ; Salim, EI; Sherif, AA | 1 |
| Mohammed Sadullah, SS; Niranjali Devaraj, S; Rathinavel, A; Sankar, J | 1 |
| Gao, H; Gao, Z; Hu, Z; Jiang, B; Li, B; Li, X; Peng, T; Yang, X | 1 |
| da Silva, LBR; de Freitas, ALD; de Mello, JCP; Ishida, K; Kaplum, V; Melhem, MSC; Nakamura, CV; Rossi, DCP; Taborda, CP | 1 |
| Balci Yuce, H; Elmastas, M; Gevrek, F; Lektemur Alpan, A; Toker, H | 1 |
| Carnovale, C; Dominighini, A; Frances, D; Galliano, S; Garcia, G; Gonzalvez, J; Luquita, A; Monti, J; Ronco, MT; Urli, L; Wagner, M | 1 |
| Ardévol, A; Blay, M; Casanova-Martí, À; Gil-Cardoso, K; Ginés, I; Pinent, M; Serrano, J; Terra, X | 1 |
| Asou, Y; Ishiyama, K; Jin, G; Kanno, T; Niwano, Y; Okawa, A | 1 |
| Lotha, R; Nagarajan, S; Shamprasad, BR; Sivasubramanian, A; Sundaramoorthy, NS | 1 |
| Koike, M; Masuda, I; Mizutani, Y; Nakashima, S; Nojiri, H; Ozawa, Y; Sashihara, K; Sawada, Y; Shimizu, T; Sugimoto, A; Sugiyama, H; Watanabe, K; Yokote, K | 1 |
| He, J; Sun, M; Tian, S | 1 |
| Erdem, U; Ilhan, A; Oztas, E; Yolcu, U | 1 |
| Chen, Y; Hu, L; Liu, B; Liu, WT; Pan, C; Pan, Y; Song, L; Wang, C; Zhang, L | 1 |
| Chen, P; Fang, S; Fu, X; Liu, Y; Shang, X; Wang, T; Zhou, M | 1 |
| Chen, H; He, P; Jiao, J; Li, S; Liu, C; Lv, Y; Mao, X; Xu, J; Xue, X | 1 |
| Gao, D; Li, W; Ma, X; Nie, X; Wang, J; Wang, W; Xing, J; Yu, Z; Zhang, X | 1 |
| Ardévol, A; Blay, M; Comitato, R; Gil-Cardoso, K; Ginés, I; Pinent, M; Terra, X; Virgili, F | 1 |
| Ashida, H; Natsume, M; Okabe, M; Yamashita, Y | 1 |
| Li, Y; Liu, C; Ma, C; Miao, Q; Sui, R; Wang, J; Wang, Q; Xiao, B; Yang, Z; Yu, J; Zhang, G | 1 |
| Huang, MX; Jiang, Y; Lei, GT; Wu, QH; Xing, YW | 1 |
| Gu, Z; Jia, H; Li, G; Li, Y; Liu, H; Liu, J; Liu, Y; Luo, L; Ren, X; Tu, X; Wang, M; Zhao, W | 1 |
| Alkanat, M; Mungan, S; Orem, A; Ozkan, G; Ulusoy, S; Yuluğ, E | 1 |
| Abd-Allah, AR; Abdel-Hamied, HE; Ahmad, SF; Ashour, AE; Attia, SM; Bakheet, SA; Zoheir, KM | 1 |
| Akita, M; Fujita, K; Furumoto, T; Hamada, K; Inami, Y; Kaneda, Y; Kitamura, K; Maeda, A; Nakaoji, K; Ozawa, N; Sahara, S; Tamai, K; Toyoshima, M; Zaiki, K | 1 |
| Byun, JK; Cho, ML; Hong, YS; Jhun, JY; Ju, JH; Kim, EK; Kim, HY; Min, JK; Moon, SJ; Park, SH; Yang, EJ; Yoon, BY | 1 |
| Chien, TY; Huang, GC; Lee, CJ; Tseng, SH; Wang, CC; Wang, KT; Weng, BC | 1 |
| Assis, LC; de Bem, AF; de Souza, GV; do Valle, RM; dos Santos, AR; Forner, S; Horst, H; Hort, MA; Koepp, J; Martini, AC; Martins, DF; Pizzolatti, MG; Rae, GA; Silva, JC | 1 |
| Bi, W; Dang, X; Liu, R; Shi, Z; Song, Q; Wang, K; Zhang, C | 1 |
| Arat, A; Goker, T; Polat, E; Sargon, MF; Tekiner, A; Yilmaz, MB | 1 |
| Arola, L; Bladé, C; Casanova, E; Fernández-Iglesias, A; Salvadó, MJ | 1 |
| Nie, X; Zhou, W | 1 |
| Akiyama, H; Kanda, T; Matsuoka, H; Nakamura, K; Nakashima, S; Nishimaki-Mogami, T | 1 |
| Li, GQ; Liu, YT; Xu, ZC; Yin, J; Yu, Y; Zhou, B | 1 |
| Ding, H; Li, J; Li, X; Li, Z; Niu, Y; Wu, S; Xiang, J; Yue, Y | 1 |
| Bedi, O; Deshmukh, R; Kaur, G; Kumar, P; Sharma, N; Singh, S | 1 |
| Cao, M; Dong, Y; Guo, H; Ye, B; Zou, S | 1 |
| Burlando, B; Cornara, L; Xiao, J | 1 |
| Gao, YQ; Gong, YS; Guo, J; Hou, FL; Hu, K; Sun, ZD; Xie, BJ; Yang, EN | 1 |
| Fujita, K; Hamada, K; Kaneda, Y; Kuge, K; Maeda, A; Nakaoji, K; Ozawa, N; Sahara, S; Takenaka, Y; Tamai, K; Tanahashi, T; Zaiki, K | 1 |
| Boeing, T; Cechinel-Filho, V; Cury, BJ; de Andrade, SF; de Barros, M; de Moura Burci, L; Monache, FD; Mota da Silva, L; Santin, JR; Somensi, LB | 1 |
| Katiyar, SK | 1 |
| Dasilva, G; Medina, I; Molinar-Toribio, E; Pérez-Jiménez, J; Ramos-Romero, S; Romeu, M; Taltavull, N; Torres, JL | 1 |
| Aragonès, G; Ardid-Ruiz, A; Bladé, C; Ibars, M; Muguerza, B; Suárez, M | 1 |
| Cai, YW; Cheng, M; Gao, HQ; Li, BY; Li, XL; Pei, F; Wang, QZ; Wang, YJ; Zhang, J; Zhang, Z; Zhou, Y | 1 |
| Gong, Y; Liao, Y; Liu, L; Sun, Z; Xie, B; Yang, E | 1 |
| Bauab, TM; Brito, AR; Hiruma-Lima, CA; Kushima, H; Moraes, Tde M; Pellizzon, CH; Rodrigues, CM; Villegas, W | 1 |
| Akiyama, H; Kanda, T; Maitani, T; Matsuda, R; Nakano, M; Ohtake, Y; Shoji, T; Takita, T; Yoshioka, Y | 1 |
| Akgul, O; Atim, A; Guven, A; Korkmaz, A; Kurt, E; Ozcan, A; Sizlan, A; Uysal, B; Yanarates, O | 1 |
| Li, W; Wu, XL; Xu, B; Xu, J | 1 |
| Bai, BR; Devaraj, SN; Karthikeyan, K | 2 |
| Berktas, M; Kankaya, D; Kankaya, Y; Karaaslan, GM; Karaaslan, O; Kocer, U; Tiftikcioglu, YO; Tuncer, S; Ulusoy, MG | 1 |
| Atim, A; Cosar, A; Guven, A; Korkmaz, A; Oztas, E; Sizlan, A; Uysal, B; Yanarates, O | 1 |
| Cho, ML; Heo, YJ; Ju, JH; Kim, HY; Min, JK; Oh, HJ; Park, JS; Park, MK; Park, SH; Woo, YJ | 1 |
| Liu, LG; Rong, S; Sun, ZD; Xie, BJ; Xu, JQ; Zhang, L; Zhang, YJ | 1 |
| Cho, EJ; Lee, YA; Yokozawa, T | 1 |
| Cho, EJ; Lee, YA; Matsumoto, K; Yokozawa, T; Zhao, Q | 1 |
| Hao, L; Liu, L; Rong, S; Sun, Z; Wu, H; Xie, B; Xu, J; Yao, P; Zhang, L | 1 |
| Jing, H; Lan, H; Liu, H; Niu, C; Zhang, T | 1 |
| Dong, Z; Gao, Y | 1 |
| Gao, H; Lu, W; Qiu, J; Wei, X; Zhao, G | 1 |
| Cui, X; Feng, H; Gao, H; Li, B; Lu, M; Xu, L; Zhang, C; Zhang, W | 1 |
| de Carvalho, CR; Duarte, FS; Horst, H; Moreira, EL; Pizzolatti, MG; Prediger, RD; Rial, D; Ribeiro-do-Valle, RM | 1 |
| Aguiar, AS; DalBó, S; De Bem, AF; de Oliveira, J; dos Santos, TS; Ferreira, J; Figueiredo, CP; Horst, H; Latini, A; Mancini, G; Marino-Neto, J; Moreira, EL; Pinheiro, FV; Pizzolatti, MG; Prediger, RD; Rial, D; Ribeiro-do-Valle, RM; Siqueira, JM; Villarinho, JG | 1 |
| Gao, S; Wang, XH; Zhang, Y; Zuo, YM | 1 |
| Ke, Z; Li, X; Shi, H; Wang, S; Wang, W; Xu, P; Zhang, Y; Zhong, Z | 1 |
| Kiso, Y; Matsumura, Y; Ohkita, M | 1 |
| Du, Q; Huang, M; Li, RR; Wei, GZ; Zhang, Q; Zhou, DY | 1 |
| Chen, X; Gao, H; Guo, TZ; Hou, YL; Kobayashi, H; Sun, SC; Tang, JS; Yao, XS; Ye, WC | 1 |
| Ge, B; Liu, X; Shi, JC; Wang, XX; Wang, YH; Wu, YJ; Yang, LN; Yang, XL; Zhai, J | 1 |
| Arola, L; Arola-Arnal, A; Bladé, C; Díaz, S; Fernández-Iglesias, A; Pajuelo, D; Quesada, H; Salvadó, J | 1 |
| Cho, ML; Jhun, JY; Joo, YB; Ju, JH; Jung, YO; Kang, CM; Kim, HY; Min, JK; Oh, HJ; Park, JS; Park, MK; Park, SH; Sung, MS; Woo, YJ | 1 |
| Ahn, SH; Hahn, SJ; Hong, YJ; Jeong, I; Jo, YH; Kim, HJ; Kim, MJ; Rhie, DJ; Yoon, SH | 1 |
| Du, F; Song, X; Sun, G; Sun, X; Tong, H | 1 |
| Aburada, M; Kamiya, T; Kamiya-Sameshima, M; Miyamoto, K; Nagamine, R; Sai, Y; Shimada, T; Takagaki, K; Tokuhara, D; Tsubata, M | 1 |
| Al, S; Alkanat, M; Ersöz, Ş; Kaynar, K; Orem, A; Ozkan, G; Ulusoy, S; Yucesan, FB; Yuluğ, E | 1 |
| Akcan, B; Al, S; Alkanat, M; Ersöz, S; Kaynar, K; Orem, A; Ozkan, G; Ulusoy, S; Yuluğ, E | 1 |
| Ardévol, A; Blay, M; Cedó, L; Montagut, G; Pinent, M | 1 |
| Aini, H; Asou, Y; Iwata, M; Koga, D; Ochi, H; Okawa, A; Okazaki, M; Sano, A | 1 |
| Al, S; Alkanat, M; Ersoz, S; Kaynar, K; Orem, A; Ozkan, G; Ulusoy, S; Yucesan, FB | 1 |
| Bang, BR; Cho, YS; Kim, TB; Kwon, HS; Lee, KY; Lee, T; Lee, YS; Moon, HB; Moon, KA; Park, MY | 1 |
| Bagchi, D; Bagchi, M; Mandarano, MA; Shuta, DL; Vinson, JA | 1 |
| Angenot, L; Damas, J; Garbacki, N; Tits, M | 1 |
| Ijiri, Y; Naemura, A; Oda, E; Sano, T; Yamakoshi, J; Yamamoto, J; Yamashita, T | 1 |
| Ariga, T | 1 |
| Frederiksen, H; Poulsen, L; Rasmussen, SE; Struntze Krogholm, K | 1 |
| Fischer, B; Gossé, F; Guyot, S; Lobstein, A; Raul, F; Roussi, S; Seiler, N | 1 |
| Akiyama, H; Goda, Y; Kanda, T; Maitani, T; Nagaoka, MH; Sato, Y; Sawada, J; Shoji, T; Teshima, R; Totsuka, M; Watanabe, T; Yamada, K; Yoshioka, Y | 1 |
| Bayraktar, MZ; Durukan, AH; Erdurman, C; Evereklioglu, C; Hurmeric, V; Kerimoglu, H; Mumcuoglu, T | 1 |
| Zaiachkivs'ka, OS | 1 |
| Cvetkovic, T; Mitic-Zlatkovic, M; Najman, S; Savic, V; Stefanovic, V; Vlahovic, P | 1 |
7 review(s) available for procyanidin and Disease Models, Animal
| Article | Year |
|---|---|
Proanthocyanidins and Flavan-3-ols in the Prevention and Treatment of Periodontitis-Immunomodulatory Effects, Animal and Clinical Studies.
Topics: Animals; Biomarkers; Clinical Studies as Topic; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Flavonoids; Humans; Immunomodulation; Inflammation Mediators; Matrix Metalloproteinases; Organ Specificity; Periodontitis; Proanthocyanidins; Treatment Outcome | 2021 |
Roles of proanthocyanidin rich extracts in obesity.
Topics: Adipose Tissue; Amylases; Animals; Body Weight; Disease Models, Animal; Energy Metabolism; Glucose; Humans; Lipase; Lipid Metabolism; Micronutrients; Obesity; Peptide Hydrolases; Proanthocyanidins; Protease Inhibitors | 2015 |
Therapeutic Potential of Temperate Forage Legumes: A Review.
Topics: Animals; Anti-Inflammatory Agents; Clinical Trials as Topic; Coumarins; Disease Models, Animal; Fabaceae; Fibrinolytic Agents; Flavonoids; Galega; Humans; Hypoglycemic Agents; Lespedeza; Lotus; Medicago; Medicago sativa; Melilotus; Phytochemicals; Plants, Medicinal; Proanthocyanidins; Saponins; Trifolium; Warfarin | 2016 |
Dietary proanthocyanidins inhibit UV radiation-induced skin tumor development through functional activation of the immune system.
Topics: Animals; Anticarcinogenic Agents; Antigen-Presenting Cells; Biological Availability; CD8-Positive T-Lymphocytes; Diet; Disease Models, Animal; DNA Damage; DNA Repair; Grape Seed Extract; Humans; Neoplasms, Radiation-Induced; Oxidative Stress; Proanthocyanidins; Skin Neoplasms; Ultraviolet Rays | 2016 |
Pharmacology in health foods: improvement of vascular endothelial function by French maritime pine bark extract (Flavangenol).
Topics: Acute Kidney Injury; Animals; Antioxidants; Biflavonoids; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Food, Organic; Humans; Hypertension; Nitric Oxide Synthase Type III; Plant Extracts; Proanthocyanidins; Reperfusion Injury | 2011 |
Procyanidins improve some disrupted glucose homoeostatic situations: an analysis of doses and treatments according to different animal models.
Topics: Animals; Blood Glucose; Dietary Supplements; Disease Models, Animal; Glucose; Glucose Metabolism Disorders; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Phytotherapy; Plant Extracts; Proanthocyanidins | 2012 |
Dietary proanthocyanidins: occurrence, dietary intake, bioavailability, and protection against cardiovascular disease.
Topics: Animals; Arteriosclerosis; Biological Availability; Cardiovascular Diseases; Diet; Disease Models, Animal; Endothelium, Vascular; Humans; Inflammation; Lipid Peroxidation; Lipoproteins, LDL; Pinus; Platelet Aggregation; Proanthocyanidins | 2005 |
1 trial(s) available for procyanidin and Disease Models, Animal
| Article | Year |
|---|---|
The effect of procyanidin on expression of STAT1 in type 2 diabetes mellitus SD rats with focal cerebral ischemia.
Topics: Animals; Apoptosis; Biflavonoids; Brain Ischemia; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Janus Kinases; Male; Neuroprotective Agents; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT1 Transcription Factor | 2014 |
120 other study(ies) available for procyanidin and Disease Models, Animal
| Article | Year |
|---|---|
First morphological-level insights into the efficiency of green tea catechins and grape seed procyanidins on a transgenic mouse model of celiac disease enteropathy.
Topics: Animals; Antioxidants; Biflavonoids; Catechin; Celiac Disease; Disease Models, Animal; Gliadin; Intestinal Diseases; Intestinal Mucosa; Male; Mice; Mice, Transgenic; Proanthocyanidins; Seeds; Tea; Vitis | 2021 |
Astilbe thunbergii reduces postprandial hyperglycemia in a type 2 diabetes rat model via pancreatic alpha-amylase inhibition by highly condensed procyanidins.
Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Glycoside Hydrolase Inhibitors; Hyperglycemia; Male; Proanthocyanidins; Rats; Saxifragaceae | 2017 |
Effects of procyanidin on cardiomyocyte apoptosis after myocardial ischemia reperfusion in rats.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Biflavonoids; Catechin; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Proanthocyanidins; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2018 |
Ingredients in Zijuan Pu'er Tea Extract Alleviate β-Amyloid Peptide Toxicity in a
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Biflavonoids; Caenorhabditis elegans; Caffeine; Catechin; Disease Models, Animal; Gene Expression Regulation; Humans; Oxidative Stress; Paralysis; Plant Extracts; Proanthocyanidins; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Tea | 2019 |
Dietary supplementation with procyanidin-rich Pinus pinaster extract is associated with attenuated Ehrlich tumor development in mice.
Topics: Animals; Biflavonoids; Carcinoma, Ehrlich Tumor; Catechin; Dietary Supplements; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Pinus; Plant Extracts; Proanthocyanidins | 2019 |
Anti-allergic effect of intranasal administration of type-A procyanidin polyphenols based standardized extract of cinnamon bark in ovalbumin sensitized BALB/c mice.
Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Biflavonoids; Catechin; Cinnamomum zeylanicum; Disease Models, Animal; Histamine; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Plant Bark; Plant Extracts; Polyphenols; Proanthocyanidins; Rhinitis, Allergic; Sneezing | 2015 |
Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways.
Topics: AMP-Activated Protein Kinases; Animals; Anthocyanins; Biflavonoids; Catechin; Disease Models, Animal; Glucose; Glucose Transporter Type 4; Glucosides; Humans; Hyperglycemia; Insulin; Mice; Muscle, Skeletal; Proanthocyanidins; Signal Transduction | 2016 |
Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1β activities before and after oral consumption.
Topics: Administration, Oral; Animals; Anterior Cruciate Ligament; Biflavonoids; Catechin; Cyclooxygenase 2; Diet; Dinoprostone; Disease Models, Animal; Female; Grape Seed Extract; Interleukin-1beta; Male; Mass Spectrometry; Matrix Metalloproteinase 13; Metabolome; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Olea; Osteoarthritis; Phenylethyl Alcohol; Proanthocyanidins; Rabbits; RNA, Messenger; Wounds and Injuries | 2016 |
Procyanidins Mitigate Osteoarthritis Pathogenesis by, at Least in Part, Suppressing Vascular Endothelial Growth Factor Signaling.
Topics: Animals; Biflavonoids; Catechin; Cells, Cultured; Chondrocytes; Collagen Type II; Disease Models, Animal; Female; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Osteoarthritis; Osteoporosis; Proanthocyanidins; Signal Transduction; Vascular Endothelial Growth Factor A | 2016 |
Regression of atherosclerosis with apple procyanidins by activating the ATP-binding cassette subfamily A member 1 in a rabbit model.
Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; ATP Binding Cassette Transporter 1; Biflavonoids; Cardiovascular Agents; Catechin; Cholesterol; Disease Models, Animal; Fruit; Lipoproteins, LDL; Male; Malus; Oxidative Stress; Phytotherapy; Plants, Medicinal; Plaque, Atherosclerotic; Proanthocyanidins; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Time Factors; Up-Regulation | 2017 |
Diverse mechanisms of antidiabetic effects of the different procyanidin oligomer types of two different cinnamon species on db/db mice.
Topics: Animals; Biflavonoids; Blood Glucose; Catechin; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Male; Mice; Phytotherapy; Plant Extracts; Proanthocyanidins | 2012 |
Administration of procyanidins from grape seeds reduces serum uric acid levels and decreases hepatic xanthine dehydrogenase/oxidase activities in oxonate-treated mice.
Topics: Allopurinol; Animals; Antioxidants; Biflavonoids; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gout Suppressants; Hyperuricemia; Liver; Male; Mice; Mice, Inbred ICR; Oxonic Acid; Proanthocyanidins; Seeds; Time Factors; Urate Oxidase; Uric Acid; Vitis; Xanthine Dehydrogenase; Xanthine Oxidase | 2004 |
Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Muscle Fibers, Skeletal; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Vitis | 2004 |
Alleviation effects of grape seed proanthocyanidin extract on inflammation and oxidative stress in a D-galactose-induced aging mouse model by modulating the gut microbiota.
Topics: Aging; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Galactose; Gastrointestinal Microbiome; Grape Seed Extract; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Proanthocyanidins | 2022 |
Proanthocyanidins from Chinese bayberry leaves reduce obesity and associated metabolic disorders in high-fat diet-induced obese mice through a combination of AMPK activation and an alteration in gut microbiota.
Topics: Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Disease Models, Animal; Functional Food; Gastrointestinal Microbiome; Liver; Male; Mice; Mice, Inbred C57BL; Myrica; Plant Extracts; Plant Leaves; Proanthocyanidins | 2022 |
Nrf2 regulates downstream genes by targeting miR-29b in severe asthma and the role of grape seed proanthocyanidin extract in a murine model of steroid-insensitive asthma.
Topics: Adult; Animals; Anti-Asthmatic Agents; Asthma; Case-Control Studies; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Female; Gene Expression Regulation; Grape Seed Extract; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Middle Aged; NF-E2-Related Factor 2; Ovalbumin; Proanthocyanidins; Severity of Illness Index | 2022 |
Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway.
Topics: Animals; Diabetes, Gestational; Disease Models, Animal; Female; Gastrointestinal Microbiome; Humans; Inflammasomes; Inflammation; Insulin; Insulin Resistance; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pregnancy; Proanthocyanidins | 2022 |
An Emerging Role of
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Imiquimod; Interleukin-17; Interleukin-23; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Proanthocyanidins; Psoriasis; Reactive Oxygen Species; RNA, Messenger; Skin; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2022 |
Procyanidins Extracted from the Lotus Seedpod Ameliorate Cognitive Impairment through CREB-BDNF Pathway Mediated LTP in
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Long-Term Potentiation; Lotus; Maze Learning; Mice; Mice, Transgenic; Neurodegenerative Diseases; Proanthocyanidins; Seeds | 2023 |
Procyanidin improves experimental colitis by regulating macrophage polarization.
Topics: Animals; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Inflammatory Bowel Diseases; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Proanthocyanidins; RAW 264.7 Cells | 2023 |
Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Mice; Plant Extracts; Proanthocyanidins; Vaccinium macrocarpon; Xenograft Model Antitumor Assays | 2019 |
Grape seed procyanidin suppresses inflammation in cigarette smoke-exposed pulmonary arterial hypertension rats by the PPAR-γ/COX-2 pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Proliferation; Cells, Cultured; Cigarette Smoking; Cyclooxygenase 2; Disease Models, Animal; Grape Seed Extract; Inflammation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Proanthocyanidins; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling | 2020 |
GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway.
Topics: Animals; Cells, Cultured; Complement C3; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Grape Seed Extract; HMGB1 Protein; Kidney; Kidney Diseases; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Proanthocyanidins; Rats; Signal Transduction; Transforming Growth Factor beta1 | 2020 |
Wild blueberry proanthocyanidins shape distinct gut microbiota profile and influence glucose homeostasis and intestinal phenotypes in high-fat high-sucrose fed mice.
Topics: Administration, Oral; Animals; Blood Glucose; Blueberry Plants; Colon; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Gastrointestinal Microbiome; Glucose; Glucose Intolerance; Humans; Insulin Resistance; Intestinal Mucosa; Male; Mice; Plant Extracts; Proanthocyanidins | 2020 |
Procyanidin B3 alleviates intervertebral disc degeneration via interaction with the TLR4/MD-2 complex.
Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Cell Death; Cell Survival; Disease Models, Animal; Disease Progression; Extracellular Matrix; Humans; Intervertebral Disc Degeneration; Lipopolysaccharides; Lymphocyte Antigen 96; Male; Myeloid Differentiation Factor 88; NF-kappa B; Nucleus Pulposus; Proanthocyanidins; Punctures; Rats, Sprague-Dawley; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4 | 2020 |
Grape Seed Proanthocyanidin Extract Ameliorates Streptozotocin-induced Cognitive and Synaptic Plasticity Deficits by Inhibiting Oxidative Stress and Preserving AKT and ERK Activities.
Topics: Alzheimer Disease; Animals; Antioxidants; Cognition; Cognitive Dysfunction; Disease Models, Animal; Glutathione; Grape Seed Extract; Hippocampus; Long-Term Potentiation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Neuronal Plasticity; Oxidative Stress; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase | 2020 |
Procyanidin B2 Improves Oocyte Maturation and Subsequent Development in Type 1 Diabetic Mice by Promoting Mitochondrial Function.
Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Mitochondria; Oocytes; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species; Streptozocin | 2020 |
Protection of procyanidin B2 on mitochondrial dynamics in sepsis associated acute kidney injury via promoting Nrf2 nuclear translocation.
Topics: Active Transport, Cell Nucleus; Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Biflavonoids; Catechin; Disease Models, Animal; Kidney; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Dynamics; Mitophagy; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Sepsis | 2020 |
Changes in arterial blood pressure caused by long-term administration of grape seed proanthocyanidins in rats with established hypertension.
Topics: Animals; Antihypertensive Agents; Antioxidants; Arterial Pressure; Blood Pressure; Diet; Disease Models, Animal; Drug Administration Schedule; Grape Seed Extract; Hypertension; Proanthocyanidins; Rats; Rats, Wistar; Time Factors | 2020 |
Grape seed proanthocyanidins protect retinal ganglion cells by inhibiting oxidative stress and mitochondrial alteration.
Topics: Administration, Oral; Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Glaucoma; Grape Seed Extract; Humans; Intraocular Pressure; Mice; Mice, Inbred DBA; Mitochondria; Neuroprotective Agents; Oxidative Stress; Proanthocyanidins; Retinal Ganglion Cells | 2020 |
A Mix of Natural Bioactive Compounds Reduces Fat Accumulation and Modulates Gene Expression in the Adipose Tissue of Obese Rats Fed a Cafeteria Diet.
Topics: Adipose Tissue; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anthocyanins; Diet; Disease Models, Animal; Energy Metabolism; Gene Expression; Grape Seed Extract; Linoleic Acids, Conjugated; Lipid Metabolism; Obesity; Oxidation-Reduction; Phytochemicals; Proanthocyanidins; Protein Hydrolysates; Rats | 2020 |
Central administration of afzelin extracted from Ribes fasciculatum improves cognitive and memory function in a mouse model of dementia.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognition; Cyclic AMP Response Element-Binding Protein; Dementia; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Long-Term Potentiation; Male; Mannosides; Memory; Mice, Inbred C57BL; Neuroprotective Agents; Proanthocyanidins; Ribes; Scopolamine | 2021 |
Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.
Topics: Animals; Autophagy; Biflavonoids; Catechin; Cold Temperature; Disease Models, Animal; Hedgehog Proteins; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Signal Transduction | 2021 |
Grape-Seed Proanthocyanidin Extract Reverts Obesity-Related Metabolic Derangements in Aged Female Rats.
Topics: Adiposity; Animals; Blood Glucose; Disease Models, Animal; Fatty Liver; Female; Glucagon; Grape Seed Extract; Insulin; Obesity; Proanthocyanidins; Rats; Rats, Wistar; Weight Loss | 2021 |
Grape seed proanthocyanidin supplementation reduces adipocyte size and increases adipocyte number in obese rats.
Topics: Adipocytes; Adiposity; Animals; Antioxidants; Disease Models, Animal; Fatty Acid-Binding Proteins; Gallic Acid; Gene Expression Regulation; Grape Seed Extract; Lipid Metabolism; Male; Obesity; Perilipin-1; Proanthocyanidins; Rats; Rats, Wistar | 2017 |
Immunohistochemical and biochemical alterations following administration of proanthocyanidin extract in rats hepatocellular carcinoma.
Topics: Animals; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Disease Models, Animal; Grape Seed Extract; Liver Neoplasms; Male; Oxidative Stress; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley | 2017 |
Oligomeric proanthocyanidins protect myocardium by mitigating left ventricular remodeling in isoproterenol-induced postmyocardial infarction.
Topics: Animals; Antioxidants; Bone Morphogenetic Protein 4; Cardiovascular Agents; Collagen; Disease Models, Animal; Fibrosis; Isoproterenol; Lipid Peroxidation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardium; Oxidative Stress; Proanthocyanidins; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Nephrin loss is reduced by grape seed proanthocyanidins in the experimental diabetic nephropathy rat model.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glycation End Products, Advanced; Grape Seed Extract; Humans; Kidney; Membrane Proteins; Oxidative Stress; Proanthocyanidins; Rats; Receptor for Advanced Glycation End Products | 2017 |
Proanthocyanidin polymeric tannins from Stryphnodendron adstringens are effective against Candida spp. isolates and for vaginal candidiasis treatment.
Topics: Administration, Intravaginal; Animals; Antifungal Agents; Biofilms; Candida albicans; Candida glabrata; Candidiasis, Vulvovaginal; Disease Models, Animal; Dose-Response Relationship, Drug; Fabaceae; Female; Gels; Mice, Inbred BALB C; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Proanthocyanidins | 2018 |
Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Grape Seed Extract; Hypoxia-Inducible Factor 1; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Ligation; Male; Matrix Metalloproteinase 8; Osteoblasts; Osteoclasts; Periodontitis; Proanthocyanidins; Rats; Rats, Wistar; Streptozocin; Tartrate-Resistant Acid Phosphatase; Vascular Endothelial Growth Factor A | 2018 |
The Enriched Proanthocyanidin Extract of Ligaria cuneifolia Shows a Marked Hypocholesterolemic Effect in Rats Fed with Cholesterol-Enriched Diet.
Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Lipid Droplets; Liver; Loranthaceae; Male; Phytotherapy; Plant Extracts; Plants, Medicinal; Proanthocyanidins; Rats, Wistar; Time Factors; Triglycerides | 2017 |
Effects of an Intermittent Grape-Seed Proanthocyanidin (GSPE) Treatment on a Cafeteria Diet Obesogenic Challenge in Rats.
Topics: Adiposity; Animals; Antioxidants; Blood Glucose; Body Composition; Body Weight; Calorimetry, Indirect; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Grape Seed Extract; Insulin; Insulin Resistance; Obesity; Proanthocyanidins; Rats; Rats, Wistar; Triglycerides; Tumor Necrosis Factor-alpha | 2018 |
Proanthocyanidin-Rich Grape Seed Extract Modulates Intestinal Microbiota in Ovariectomized Mice.
Topics: Animals; Bacteroidetes; Diet; Disease Models, Animal; DNA, Bacterial; Feces; Female; Firmicutes; Gastrointestinal Microbiome; Grape Seed Extract; Mice; Ovariectomy; Polyphenols; Proanthocyanidins; RNA, Ribosomal, 16S; Weight Gain | 2018 |
Plant nutraceuticals (Quercetrin and Afzelin) capped silver nanoparticles exert potent antibiofilm effect against food borne pathogen Salmonella enterica serovar Typhi and curtail planktonic growth in zebrafish infection model.
Topics: Adhesins, Bacterial; Animals; Anti-Bacterial Agents; Bacteria; Biofilms; Dietary Supplements; Disease Models, Animal; Fabaceae; Foodborne Diseases; Green Chemistry Technology; Hydrophobic and Hydrophilic Interactions; Mannosides; Membrane Potentials; Metal Nanoparticles; Microbial Sensitivity Tests; Proanthocyanidins; Pseudomonas aeruginosa; Quercetin; Salmonella typhi; Silver; Toxicity Tests; Zebrafish | 2018 |
Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes.
Topics: Animals; Cartilage, Articular; Cell Line; Chondrocytes; Disease Models, Animal; DNA, Mitochondrial; Gene Expression; Humans; Male; Malus; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Organelle Biogenesis; Osteoarthritis; Paraquat; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Primary Cell Culture; Proanthocyanidins; Proteoglycans; Superoxide Dismutase | 2018 |
Procyanidin B2 prevents lupus nephritis development in mice by inhibiting NLRP3 inflammasome activation.
Topics: Animals; Antibodies, Antinuclear; Biflavonoids; Catechin; Cells, Cultured; Disease Models, Animal; Female; Humans; Inflammasomes; Kidney; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; NLR Family, Pyrin Domain-Containing 3 Protein; Proanthocyanidins; RNA, Small Interfering; Signal Transduction | 2018 |
Therapeutic effects of proanthocyanidin and coenzyme Q10 on nitrogen mustard-induced ocular injury.
Topics: Animals; Antioxidants; Burns, Chemical; Chemical Warfare Agents; Disease Models, Animal; Eye Injuries; Male; Mechlorethamine; Proanthocyanidins; Random Allocation; Rats; Rats, Sprague-Dawley; Ubiquinone | 2018 |
Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Calcium-Binding Proteins; Cell Line, Transformed; Cytokines; Disease Models, Animal; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Microfilament Proteins; Microglia; NF-kappa B; Pain Measurement; Proanthocyanidins; Sciatic Neuropathy; Signal Transduction | 2018 |
Geographic Variation in the Chemical Composition and Antioxidant Properties of Phenolic Compounds from
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Diabetes Mellitus; Disease Models, Animal; Glucuronides; Juglandaceae; Kaempferols; Male; Mannosides; Mice; Molecular Structure; Phenols; Plant Extracts; Plant Leaves; Proanthocyanidins; Quercetin; Superoxide Dismutase | 2018 |
Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; Cell Proliferation; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinases; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; PC12 Cells; Proanthocyanidins; Rats; Reactive Oxygen Species; Signal Transduction | 2018 |
Epicatechin alleviates inflammation in lipopolysaccharide-induced acute lung injury in mice by inhibiting the p38 MAPK signaling pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Proanthocyanidins; Protein Binding | 2019 |
Protective Effect of Proanthocyanidins in a Rat Model of Mild Intestinal Inflammation and Impaired Intestinal Permeability Induced by LPS.
Topics: Administration, Oral; Animals; Cyclooxygenase 2; Disease Models, Animal; Gastroenteritis; Gene Expression Regulation; Grape Seed Extract; Intestines; Lipopolysaccharides; Male; Ovalbumin; Oxidative Stress; Permeability; Proanthocyanidins; Protective Agents; Rats, Wistar | 2019 |
Cacao liquor procyanidins prevent postprandial hyperglycaemia by increasing glucagon-like peptide-1 activity and AMP-activated protein kinase in mice.
Topics: AMP-Activated Protein Kinases; Animals; Cacao; Disease Models, Animal; Glucagon-Like Peptide 1; Glucose; Glucose Transporter Type 4; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Phosphorylation; Plant Extracts; Polyphenols; Proanthocyanidins; Signal Transduction | 2019 |
Therapeutic effect of oligomeric proanthocyanidin in cuprizone-induced demyelination.
Topics: Animals; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Mice; Oligodendroglia; Proanthocyanidins; Treatment Outcome | 2019 |
Procyanidin B2 protects against diet-induced obesity and non-alcoholic fatty liver disease
Topics: Animals; Bacteroidetes; Biflavonoids; Biomarkers; Body Weight; Catechin; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Insulin Resistance; Lipopolysaccharides; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Proanthocyanidins; Protective Agents; Rabbits; RNA, Ribosomal, 16S; Treatment Outcome; Triglycerides | 2019 |
Pretreatment of Grape Seed Proanthocyanidin Extract Exerts Neuroprotective Effect in Murine Model of Neonatal Hypoxic-ischemic Brain Injury by Its Antiapoptotic Property.
Topics: Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Brain Injuries; Disease Models, Animal; Grape Seed Extract; Hypoxia-Ischemia, Brain; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Plant Extracts; Proanthocyanidins | 2019 |
Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options.
Topics: Acute Kidney Injury; Animals; Apoptosis; Calpain; Caspase 1; Caspase 3; Disease Models, Animal; Female; Grape Seed Extract; Kidney; Necrosis; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Rhabdomyolysis; Time Factors | 2013 |
Grape seed proanthocyanidin extract protects against carrageenan-induced lung inflammation in mice through reduction of pro-inflammatory markers and chemokine expressions.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemokines; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Glucocorticoid-Induced TNFR-Related Protein; Grape Seed Extract; Inflammation Mediators; Lung; Mice; Mice, Inbred BALB C; Pleurisy; Pneumonia; Proanthocyanidins; Th1 Cells; Th17 Cells; Th2 Cells | 2014 |
Mallotus philippinensis bark extracts promote preferential migration of mesenchymal stem cells and improve wound healing in mice.
Topics: Animals; Chemotactic Factors; Chemotaxis; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Leukocytes, Mononuclear; Mallotus Plant; Mesenchymal Stem Cells; Mice; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Wound Healing; Wounds and Injuries | 2014 |
Grape seed proanthocyanidin extract-mediated regulation of STAT3 proteins contributes to Treg differentiation and attenuates inflammation in a murine model of obesity-associated arthritis.
Topics: Administration, Oral; Animals; Arthritis; Arthritis, Experimental; Cell Differentiation; Cytokines; Diet, High-Fat; Disease Models, Animal; Gene Expression; Grape Seed Extract; Humans; Inflammation; Inflammation Mediators; Mice, Inbred C57BL; Microscopy, Confocal; Obesity; Proanthocyanidins; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2013 |
Immunomodulatory effects of Hedysarum polybotrys extract in mice macrophages, splenocytes and leucopenia.
Topics: Animals; Astragalus Plant; Astragalus propinquus; Cell Line; Daunorubicin; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Immunologic Factors; Isoflavones; Leukopenia; Macrophages; Mice; Nitric Oxide; Plant Extracts; Proanthocyanidins; Quality Control; Spleen | 2013 |
Neuroprotective effect of the proanthocyanidin-rich fraction in experimental model of spinal cord injury.
Topics: Animals; Antioxidants; Cell Death; Croton; Disease Models, Animal; Ganglia, Spinal; Glutamic Acid; Male; Movement; Muscle Strength; Neuroprotective Agents; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Rats, Wistar; Reactive Oxygen Species; Receptors, Glutamate; Spinal Cord Injuries | 2014 |
Beneficial effect of grape seed proanthocyanidin extract in rabbits with steroid-induced osteonecrosis via protecting against oxidative stress and apoptosis.
Topics: Animals; Apoptosis; Disease Models, Animal; Glucocorticoids; Grape Seed Extract; Male; Methylprednisolone; Osteonecrosis; Oxidative Stress; Proanthocyanidins; Rabbits | 2015 |
The therapeutic value of proanthocyanidin in experimental cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Basilar Artery; Disease Models, Animal; Male; Proanthocyanidins; Rabbits; Radiography; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2014 |
Afzelin attenuates asthma phenotypes by downregulation of GATA3 in a murine model of asthma.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Eosinophils; GATA3 Transcription Factor; Gene Expression Regulation; Humans; Immunoglobulin E; Mannosides; Mice; Ovalbumin; Proanthocyanidins; Th2 Cells | 2015 |
Oral administration of apple condensed tannins delays rheumatoid arthritis development in mice via downregulation of T helper 17 (Th17) cell responses.
Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Cells, Cultured; Cytokines; Disease Models, Animal; Down-Regulation; Interleukin-17; Malus; Mice, Inbred DBA; Proanthocyanidins; Spleen; Th17 Cells | 2015 |
Grape seed proanthocyanidin protects liver against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Grape Seed Extract; Inflammation Mediators; Liver; Liver Diseases; Male; Oxidative Stress; Proanthocyanidins; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2015 |
Procyanidin B2 attenuates neurological deficits and blood-brain barrier disruption in a rat model of cerebral ischemia.
Topics: Animals; Biflavonoids; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Catechin; Disease Models, Animal; Glutathione Transferase; Heme Oxygenase-1; Inactivation, Metabolic; Infarction, Middle Cerebral Artery; Isoenzymes; Male; NAD(P)H Dehydrogenase (Quinone); Neuroprotective Agents; Oxidative Stress; Permeability; Proanthocyanidins; Rats, Sprague-Dawley; Tight Junctions | 2015 |
Anti-hyperalgesic and anti-nociceptive potentials of standardized grape seed proanthocyanidin extract against CCI-induced neuropathic pain in rats.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Grape Seed Extract; Hyperalgesia; Male; Morphine; Neuralgia; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar | 2016 |
Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 in Caenorhabditis elegans Model of Alzheimer's Disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; DNA-Binding Proteins; Forkhead Transcription Factors; Heat Shock Transcription Factors; Immunity, Innate; Plant Extracts; Proanthocyanidins; Protective Agents; Signal Transduction; Transcription Factors; Vaccinium macrocarpon | 2016 |
Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by D-galactose.
Topics: Age Factors; Aging; Animals; Avoidance Learning; Behavior, Animal; Biomarkers; Cognition; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Galactose; Hippocampus; Lotus; Male; Maze Learning; Memory; Mice; Neurons; Neuroprotective Agents; Phytotherapy; Plant Extracts; Plants, Medicinal; Proanthocyanidins; Seeds; Time Factors | 2016 |
Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Flavonoids; Male; Mesenchymal Stem Cells; Mice; Polyphenols; Proanthocyanidins; Wound Healing | 2015 |
Pharmacological reports about gastroprotective effects of methanolic extract from leaves of Solidago chilensis (Brazilian arnica) and its components quercitrin and afzelin in rodents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Cell Line; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fibroblasts; Gastric Mucosa; Glutathione; H(+)-K(+)-Exchanging ATPase; Hydrogen-Ion Concentration; Mannosides; Methanol; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Proanthocyanidins; Proton Pump Inhibitors; Quercetin; Rabbits; Rats, Wistar; Solidago; Solvents; Stomach Ulcer; Tumor Necrosis Factor-alpha; Wound Healing | 2016 |
The combined action of omega-3 polyunsaturated fatty acids and grape proanthocyanidins on a rat model of diet-induced metabolic alterations.
Topics: Adiponectin; Adiposity; Animals; Blood Glucose; Body Weight; Cholesterol; Diet; Dietary Supplements; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Female; Ghrelin; Glucagon; Insulin; Leptin; Metabolic Syndrome; Proanthocyanidins; Rats; Rats, Inbred WKY; Triglycerides; Vitis | 2016 |
Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity.
Topics: Animals; Body Weight; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Grape Seed Extract; Hypothalamus; Leptin; Lipid Metabolism; Male; Obesity; Pro-Opiomelanocortin; Proanthocyanidins; Rats; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor | 2017 |
Restoration of Mimecan Expression by Grape Seed Procyanidin B2 Through Regulation of Nuclear Factor-kappaB in Mice With Diabetic Nephropathy.
Topics: Albuminuria; Animals; Biflavonoids; Blotting, Western; Body Weight; Catechin; Cholesterol; Diabetes Mellitus; Diabetic Nephropathies; Disease Models, Animal; Glomerular Basement Membrane; Glycation End Products, Advanced; Grape Seed Extract; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Mesangial Cells; Mice; NF-kappa B; Oxidative Stress; Proanthocyanidins; Triglycerides | 2016 |
Ameliorative effects of lotus seedpod proanthocyanidins on cognitive deficits and oxidative damage in senescence-accelerated mice.
Topics: Aging; Aging, Premature; Analysis of Variance; Animals; Body Weight; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione Peroxidase; Lipid Peroxidation; Male; Maze Learning; Mice; Mice, Mutant Strains; Oxidative Stress; Proanthocyanidins; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
Hancornia speciosa: indications of gastroprotective, healing and anti-Helicobacter pylori actions.
Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Apocynaceae; Brazil; Disease Models, Animal; Gastric Juice; Gastric Mucosa; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Male; Medicine, Traditional; Mice; Plant Bark; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Stomach Ulcer | 2008 |
Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Cell Line; Colon; Dextran Sulfate; Disease Models, Animal; Humans; Inflammatory Bowel Diseases; Interferon-gamma; Interleukin-8; Malus; Mice; Mice, Inbred C57BL; Oxazolone; Proanthocyanidins; T-Lymphocytes | 2008 |
Ameliorative effects of proanthocyanidin on renal ischemia/reperfusion injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Aspartate Aminotransferases; Creatinine; Disease Models, Animal; Kidney Function Tests; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2008 |
Procyanidins produce significant attenuation of doxorubicin-induced cardiotoxicity via suppression of oxidative stress.
Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Cardiotonic Agents; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Interactions; Electrocardiography; Grape Seed Extract; Heart Diseases; Humans; Male; Myocytes, Cardiac; Oxidative Stress; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley | 2009 |
Efficacy of grape seed proanthocyanidins on cardioprotection during isoproterenol-induced myocardial injury in rats.
Topics: Administration, Oral; Animals; Antioxidants; Biomarkers; Blood Chemical Analysis; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Grape Seed Extract; Isoproterenol; Lipid Metabolism; Male; Myocardial Ischemia; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2009 |
Protective effect of grape seed extract against ischaemia/reperfusion injury in a rat epigastricflap model.
Topics: Animals; Antioxidants; Disease Models, Animal; Follow-Up Studies; Graft Survival; Grape Seed Extract; Male; Neovascularization, Physiologic; Proanthocyanidins; Rats; Rats, Wistar; Reperfusion Injury; Skin Transplantation; Surgical Flaps; Treatment Outcome | 2010 |
Proanthocyanidin protects intestine and remote organs against mesenteric ischemia/reperfusion injury.
Topics: Administration, Oral; Animals; Antioxidants; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Immunohistochemistry; Ischemia; Male; Mesentery; Proanthocyanidins; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Statistics, Nonparametric | 2009 |
Grape seed proanthocyanidin extract (GSPE) attenuates collagen-induced arthritis.
Topics: Acid Phosphatase; Animals; Ankle Joint; Antibodies; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Collagen Type II; Disease Models, Animal; Grape Seed Extract; Hydrogen Peroxide; Interleukin-17; Isoenzymes; Isoprostanes; Macrophage Colony-Stimulating Factor; Mice; Mice, Inbred DBA; Osteoclasts; Plant Extracts; Proanthocyanidins; RANK Ligand; Spleen; Tartrate-Resistant Acid Phosphatase; Tumor Necrosis Factor-alpha | 2009 |
The mixture of procyanidins extracted from the lotus seed pod and bilobalide ameliorates scopolamine-induced memory impairment in mice.
Topics: Animals; Behavior, Animal; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Furans; Ginkgolides; Lotus; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred Strains; Plant Extracts; Proanthocyanidins; Reaction Time; Scopolamine; Seeds; Statistics, Nonparametric | 2009 |
Oligomeric proanthocyanidins improve memory and enhance phosphorylation of vascular endothelial growth factor receptor-2 in senescence-accelerated mouse prone/8.
Topics: Aging; Animals; Brain; Cinnamates; Diospyros; Disease Models, Animal; Fruit; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; Neurofilament Proteins; Neurons; Neuroprotective Agents; Phosphorylation; Phytotherapy; Plant Extracts; Proanthocyanidins; Spatial Behavior; Synaptophysin; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
Persimmon oligomeric proanthocyanidins extend life span of senescence-accelerated mice.
Topics: Aging; Animals; Behavior, Animal; Diospyros; Disease Models, Animal; Gene Expression; Humans; Life Expectancy; Male; Mice; Plant Extracts; Proanthocyanidins; Random Allocation; Sirtuin 1 | 2009 |
Procyanidins extracted from the lotus seedpod ameliorate age-related antioxidant deficit in aged rats.
Topics: Aging; Aging, Premature; Animals; Antioxidants; Disease Models, Animal; Female; Lipid Peroxidation; Lotus; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds | 2010 |
[Vasorelaxant effects of procyanidins on rabbit pulmonic ring in vitro].
Topics: Animals; Disease Models, Animal; Female; Heart Diseases; Humans; In Vitro Techniques; Male; Proanthocyanidins; Pulmonary Artery; Rabbits; Random Allocation; Vasodilation; Vasodilator Agents | 2009 |
[Protective effect of procyanidins on experimental rats with intracerebral hemorrhage].
Topics: Animals; Brain; Cerebral Hemorrhage; Disease Models, Animal; Female; Humans; Male; Malondialdehyde; Proanthocyanidins; Protective Agents; Rats; Rats, Sprague-Dawley | 2009 |
The molecular mechanism of protective effects of grape seed proanthocyanidin extract on reperfusion arrhythmias in rats in vivo.
Topics: Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Free Radicals; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phytotherapy; Plant Extracts; Proanthocyanidins; Protein Structure, Tertiary; Proteomics; Rats; Rats, Wistar; Seeds; Sodium-Potassium-Exchanging ATPase; Staining and Labeling; Tachycardia, Ventricular; Ventricular Fibrillation; Vitis | 2010 |
Protective effects of grape seed proanthocyanidin extracts on cerebral cortex of streptozotocin-induced diabetic rats through modulating AGEs/RAGE/NF-kappaB pathway.
Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Brain Diseases, Metabolic; Cerebral Cortex; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Grape Seed Extract; Intercellular Adhesion Molecule-1; Male; NF-kappa B; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Streptozocin; Vascular Cell Adhesion Molecule-1 | 2010 |
Central nervous system activity of the proanthocyanidin-rich fraction obtained from Croton celtidifolius in rats.
Topics: Anesthetics, Inhalation; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Apomorphine; Behavior, Animal; Central Nervous System Agents; Consciousness; Croton; Disease Models, Animal; Dose-Response Relationship, Drug; Ether; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Motor Activity; Pentylenetetrazole; Plant Bark; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seizures; Stereotyped Behavior | 2010 |
Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson's disease.
Topics: Administration, Intranasal; Animals; Croton; Disease Models, Animal; Male; Neuroprotective Agents; Parkinsonian Disorders; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar | 2010 |
Oligomerized grape seed proanthocyanidins ameliorates isoproterenol-induced cardiac remodeling in rats: role of oxidative stress.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cyclooxygenase 2; Disease Models, Animal; Grape Seed Extract; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Malondialdehyde; MAP Kinase Kinase Kinase 5; NF-kappa B; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Superoxide Dismutase; Ventricular Remodeling; Vitis | 2011 |
Antithrombotic effect of grape seed proanthocyanidins extract in a rat model of deep vein thrombosis.
Topics: ADAM Proteins; ADAMTS13 Protein; Administration, Oral; Animals; Antigens, CD34; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Fibrinolytic Agents; Interleukin-6; Interleukin-8; Ligation; Male; Microscopy, Electron, Transmission; P-Selectin; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Time Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor Receptor-2; Vena Cava, Inferior; Venous Thrombosis; Vitis; von Willebrand Factor | 2011 |
Grape seed proanthocyanidin extract attenuates airway inflammation and hyperresponsiveness in a murine model of asthma by downregulating inducible nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Eosinophils; Female; Grape Seed Extract; Immunoglobulin E; Inflammation; Interferon-gamma; Interleukin-13; Interleukin-4; Lung; Lymphocytes; Macrophages; Mice; Mice, Inbred BALB C; Neutrophils; Nitric Oxide Synthase Type II; Ovalbumin; Proanthocyanidins; Random Allocation; Vitis | 2011 |
Polyphenols from Parabarium huaitingii and their positive inotropic and anti-myocardial infarction effects in rats.
Topics: Animals; Apocynaceae; Calcium; Cardiotonic Agents; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Medicine, Chinese Traditional; Myocardial Contraction; Myocardial Infarction; Plant Extracts; Plant Stems; Plants, Medicinal; Proanthocyanidins; Prohibitins; Random Allocation; Rats; Rats, Wistar; Stimulation, Chemical | 2011 |
Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis.
Topics: Animals; Colitis, Ulcerative; Colon; Disease Models, Animal; Humans; Immunomodulation; Inflammation; Male; NF-kappa B; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Recurrence; Seeds; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Vitis | 2011 |
Improvement of mitochondrial function in muscle of genetically obese rats after chronic supplementation with proanthocyanidins.
Topics: Animals; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Female; Grape Seed Extract; Humans; Mitochondria; Muscle, Skeletal; Obesity; Oxidation-Reduction; Oxidative Phosphorylation; Proanthocyanidins; Rats; Rats, Transgenic; Rats, Zucker | 2011 |
Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis.
Topics: Analgesics; Animals; Antioxidants; Bone Resorption; Disease Models, Animal; Gene Expression Regulation; Humans; Interleukin-1beta; Iodoacetates; Knee Joint; Male; Matrix Metalloproteinase 13; Osteoarthritis; Pain; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Tomography, Emission-Computed; Tyrosine; Vitis | 2011 |
Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons.
Topics: Animals; Antioxidants; Calcium Signaling; Cell Death; Cells, Cultured; Disease Models, Animal; Glutamates; Grape Seed Extract; Hippocampus; Neurons; Nitric Oxide; Proanthocyanidins; Rats | 2011 |
Immunomodulatory and antitumor activities of grape seed proanthocyanidins.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Grape Seed Extract; Humans; Immunologic Factors; Lymphocytes; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Proanthocyanidins; Sarcoma; Tumor Necrosis Factor-alpha | 2011 |
Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models.
Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus; Disease Models, Animal; Fatty Acids; Fatty Liver; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Liver Function Tests; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction; Pinus; Plant Bark; Plant Extracts; Proanthocyanidins; RNA, Messenger; Tomography, X-Ray Computed | 2012 |
Anti-apoptotic and anti-oxidant effects of grape seed proanthocyanidin extract in preventing cyclosporine A-induced nephropathy.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytoprotection; Disease Models, Animal; Female; Grape Seed Extract; Kidney; Kidney Diseases; Malondialdehyde; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Antiapoptotic and antioxidant effects of GSPE in preventing cyclosporine A-induced cardiotoxicity.
Topics: Animals; Antioxidants; Apoptosis; Cyclosporine; Disease Models, Animal; Female; Free Radical Scavengers; Grape Seed Extract; Heart; Heart Diseases; Immunosuppressive Agents; In Situ Nick-End Labeling; Myocardium; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Vitis | 2012 |
Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model.
Topics: Animals; Apoptosis; Biflavonoids; Cartilage, Articular; Catechin; Cell Differentiation; Chondrocytes; Disease Models, Animal; Knee Joint; Male; Mice; Nitric Oxide Synthase Type I; Ossification, Heterotopic; Osteoarthritis, Knee; Proanthocyanidins | 2012 |
Protective effect of the grape seed proanthocyanidin extract in a rat model of contrast-induced nephropathy.
Topics: Animals; Contrast Media; Disease Models, Animal; Female; Grape Seed Extract; Kidney Diseases; Plant Extracts; Proanthocyanidins; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Chemokine CCL11; Chronic Disease; Disease Models, Animal; Female; Fibrosis; Gene Expression; Glutathione; Grape Seed Extract; Inflammation; Interleukin-13; Interleukin-4; Interleukin-5; Leukocytes, Mononuclear; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Proanthocyanidins | 2012 |
Beneficial effects of a novel IH636 grape seed proanthocyanidin extract and a niacin-bound chromium in a hamster atherosclerosis model.
Topics: Animals; Arteriosclerosis; Cholesterol; Chromium; Cricetinae; Disease Models, Animal; Grape Seed Extract; Male; Mesocricetus; Niacin; Plant Extracts; Proanthocyanidins; Thiobarbituric Acid Reactive Substances; Triglycerides | 2002 |
Inhibitory effects of proanthocyanidins from Ribes nigrum leaves on carrageenin acute inflammatory reactions induced in rats.
Topics: Animals; Carrageenan; Cytokines; Disease Models, Animal; Edema; Inflammation; Male; Nitrates; Nitrites; Plant Leaves; Pleurisy; Proanthocyanidins; Rats; Rats, Wistar; Ribes | 2004 |
Anti-thrombotic effect of proanthocyanidin, a purified ingredient of grape seed.
Topics: Animals; Blood Coagulation Tests; Carotid Arteries; Disease Models, Animal; Fibrinolytic Agents; Mice; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Proanthocyanidins; Seeds; Stress, Mechanical; Thrombosis; Vitis; Wine | 2005 |
The antioxidative function, preventive action on disease and utilization of proanthocyanidins.
Topics: Animals; Anti-Ulcer Agents; Antioxidants; Aorta; Arteriosclerosis; Disease Models, Animal; Humans; Phytotherapy; Proanthocyanidins; Rabbits; Rats; Seeds; Vitis | 2004 |
Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis.
Topics: Administration, Oral; Animals; Apoptosis; Carcinoma; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Disease Models, Animal; Flavonoids; Male; Malus; Neoplasm Metastasis; Phenols; Polyphenols; Proanthocyanidins; Rats; Rats, Wistar; Signal Transduction | 2005 |
Dietary unripe apple polyphenol inhibits the development of food allergies in murine models.
Topics: Allergens; Animals; Body Temperature; Body Weight; Disease Models, Animal; Female; Flavonoids; Food Hypersensitivity; Histamine; Immunoglobulin E; Immunoglobulin G; Intestinal Mucosa; Malus; Mice; Mice, Inbred Strains; Ovalbumin; Phenols; Polyphenols; Proanthocyanidins; Receptors, Antigen, T-Cell, gamma-delta; T-Lymphocytes | 2005 |
Ingestion of IH636 grape seed proanthocyanidin extract to prevent selenite-induced oxidative stress in experimental cataract.
Topics: Administration, Oral; Animals; Cataract; Diet; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Grape Seed Extract; Lens, Crystalline; Male; Malondialdehyde; Oxidative Stress; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Sodium Selenite | 2006 |
Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats.
Topics: Animals; Biomarkers; Biopsy, Needle; Blood Chemical Analysis; Cardiotonic Agents; Disease Models, Animal; Grape Seed Extract; Immunohistochemistry; Isoproterenol; Male; Myocardial Ischemia; Oxidation-Reduction; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity | 2007 |
[Molecular mechanisms of cytoprotective action of the plant proanthocyanidins in gastric lesions].
Topics: Animals; Antioxidants; Citrus paradisi; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Gastritis; Male; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Seeds | 2006 |
Reversal of experimental myoglobinuric acute renal failure with bioflavonoids from seeds of grape.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Anthocyanins; Antioxidants; Disease Models, Animal; Flavonoids; Glycerol; Injections, Intraperitoneal; Kidney; Kidney Function Tests; Male; Malondialdehyde; Myoglobinuria; Proanthocyanidins; Probability; Rats; Rats, Wistar; Reference Values; Rhabdomyolysis; Rosales | 2000 |