Page last updated: 2024-09-02

procyanidin and Diabetes Mellitus, Type 2

procyanidin has been researched along with Diabetes Mellitus, Type 2 in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (15.63)29.6817
2010's17 (53.13)24.3611
2020's10 (31.25)2.80

Authors

AuthorsStudies
Du, W; Huang, X; Wang, Y; Xu, J; Yin, G; Zheng, T1
Li, S; Li, X; Sui, Y; Sun, Z; Xie, B1
Inagaki, Y; Kato, E; Kawabata, J; Kurokawa, M; Kushibiki, N1
Liu, CX; Min, LQ; Song, CG; Yang, X; Zhao, CS1
Ardevol, A; Arola, L; Blay, M; Casanova-Marti, A; Gonzalez-Abuin, N; Pinent, M1
Fujimoto, S; Fujita, N; Inagaki, N; Mukai, E; Nagashima, K; Ogura, K; Ogura, M; Sato, H; Sato, Y; Shoji, T; Sugizaki, K; Tahara, Y; Tatsuoka, H; Usui, R; Yamano, G1
Huang, C; Jia, Q; Li, Y; Lu, Z; Wang, R; Wu, X; Wu, Y1
Chen, K; Chen, L; Jia, Q; Li, Y; Sun, P; Wang, H; Wang, T1
Ardévol, A; Arola, L; Bladé, C; Blay, M; Fernández-Larrea, J; Pinent, M; Pujadas, G; Salvadó, MJ1
Chamasemani, A; Firouzabadi, N; Mousaei, M; Shirazi-Tehrani, E1
Huang, B; Liu, M; Liu, R; Lu, Q; Wang, L1
de Camargo, AC; Pinaffi, ACDC; Sampaio, GR; Shahidi, F; Soares, MJ; Torres, EAFS1
Hu, Y; Khadka, RB; Liu, M; Peng, X; Yang, J; Yun, P1
Andrade, PB; Neves, D; Rocha, L; Valentão, P; Videira, RA1
Adamska-Patruno, E; Ciborowski, M; Galli, M; Hameed, A; Krętowski, A1
Fu, R; Li, B; Li, Z; Tan, H; Teng, W; Tian, J; Zhang, Y1
Jindo, M; Kashiwada, M; Katsumoto, K; Katsura, K; Miyahara, Y; Nakaishi, S; Nakajima, S; Ochiai, W; Ogawa, S; Sugiyama, K; Terakado, I; Usuda, A1
Buys, AV; Pretorius, E; Soma, P; van Staden, PJ; Visser, J1
Chen, KX; Jia, Q; Li, YM; Wang, XP; Wang, Z1
Cheng, B; Gong, H; Huang, K; Huang, L; Jiao, L; Li, Y; Liu, Q; Sun, Y; Zhang, X; Zheng, L1
Dai, X; Ding, Y; Jiang, Y; Li, Y; Zhang, Z1
Amiano, P; Boeing, H; Bredsdorff, L; Buijsse, B; Fagherazzi, G; Feskens, EJ; Forouhi, NG; Franks, PW; González, CA; Grioni, S; Guevara, M; Katzke, V; Key, TJ; Khaw, KT; Kühn, T; Langenberg, C; Masala, G; Mattiello, A; Molina-Montes, E; Nilsson, PM; Overvad, K; Perquier, F; Redondo, ML; Riboli, E; Ricceri, F; Rolandsson, O; Romieu, I; Roswall, N; Scalbert, A; Schulze, M; Sharp, SJ; Slimani, N; Spijkerman, AM; Tjonneland, A; Tormo, MJ; Touillaud, M; Tumino, R; van der A, DL; van der Schouw, YT; van Woudenbergh, GJ; Wareham, NJ; Zamora-Ros, R1
Cai, X; Dai, X; Ding, Y; Jiang, Y; Li, Y; Ma, X; Zhang, Z1
Bao, L; Dai, X; Ding, Y; Jiang, Y; Li, Y; Zhang, Z1
Cai, Q; Cheng, M; Gao, H; Li, B; Li, X; Yin, W; Yu, F; Zhang, Z1
Afshari, G; Ahangarpour, A; Hashemitabar, M; Khodadadi, A; Mard, SA1
Cho, EJ; Lee, YA; Yokozawa, T1
Kempema, A; Kraus, GA; Yuan, Y1
Matalka, KZ; Nahrstedt, A; Petereit, F; Qa'dan, F; Verspohl, EJ1
Ardévol, A; Blay, M; Garcia-Vallvé, S; González-Abuín, N; Martínez-Micaelo, N; Pinent, M; Pujadas, G1
Sathya, A; Siddhuraju, P1
Altarejos, J; Bartegi, A; Bouaziz, A; Linares-Palomino, PJ; Rosado, JA; Salido, GM; Salido, S; Sanchez, A1

Reviews

5 review(s) available for procyanidin and Diabetes Mellitus, Type 2

ArticleYear
Procyanidins and their healthy protective effects against type 2 diabetes.
    Current medicinal chemistry, 2015, Volume: 22, Issue:1

    Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Proanthocyanidins

2015
Procyanidin effects on adipocyte-related pathologies.
    Critical reviews in food science and nutrition, 2006, Volume: 46, Issue:7

    Topics: Adipocytes; Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Obesity; Proanthocyanidins

2006
Effects of Grape Seed Proanthocyanidin Extract on Obesity.
    Obesity facts, 2020, Volume: 13, Issue:2

    Topics: Animals; Diabetes Mellitus, Type 2; Grape Seed Extract; Humans; Metabolic Syndrome; Obesity; Phytotherapy; Plant Extracts; Proanthocyanidins; Weight Loss

2020
Select Polyphenol-Rich Berry Consumption to Defer or Deter Diabetes and Diabetes-Related Complications.
    Nutrients, 2020, Aug-21, Volume: 12, Issue:9

    Topics: Anthocyanins; Antioxidants; Diabetes Mellitus, Type 2; Dietary Supplements; Eating; Flavonoids; Fruit; Functional Food; Humans; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Metabolic Syndrome; Nutritional Physiological Phenomena; Oxidative Stress; Phytotherapy; Polyphenols; Proanthocyanidins

2020
[Advances of mechanism research on procyanidin in prevention and treatment of type 2 diabetes mellitus].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:20

    Topics: Blood Glucose; Diabetes Mellitus, Type 2; Humans; Islets of Langerhans; Proanthocyanidins

2017

Trials

1 trial(s) available for procyanidin and Diabetes Mellitus, Type 2

ArticleYear
The effect of procyanidin on expression of STAT1 in type 2 diabetes mellitus SD rats with focal cerebral ischemia.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Animals; Apoptosis; Biflavonoids; Brain Ischemia; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Gene Expression Regulation; Janus Kinases; Male; Neuroprotective Agents; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT1 Transcription Factor

2014

Other Studies

26 other study(ies) available for procyanidin and Diabetes Mellitus, Type 2

ArticleYear
Procyanidine resists the fibril formation of human islet amyloid polypeptide.
    International journal of biological macromolecules, 2021, Jul-31, Volume: 183

    Topics: Alzheimer Disease; Amyloid; Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Proanthocyanidins

2021
Diabetes diminishes a typical metabolite of litchi pericarp oligomeric procyanidins (LPOPC) in urine mediated by imbalanced gut microbiota.
    Food & function, 2021, Jun-21, Volume: 12, Issue:12

    Topics: Animals; Antioxidants; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fasting; Fruit; Gastrointestinal Microbiome; Litchi; Male; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; RNA, Ribosomal, 16S

2021
Astilbe thunbergii reduces postprandial hyperglycemia in a type 2 diabetes rat model via pancreatic alpha-amylase inhibition by highly condensed procyanidins.
    Bioscience, biotechnology, and biochemistry, 2017, Volume: 81, Issue:9

    Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon-Like Peptide-1 Receptor; Glycoside Hydrolase Inhibitors; Hyperglycemia; Male; Proanthocyanidins; Rats; Saxifragaceae

2017
Oral Administration of Apple Procyanidins Ameliorates Insulin Resistance via Suppression of Pro-Inflammatory Cytokine Expression in Liver of Diabetic ob/ob Mice.
    Journal of agricultural and food chemistry, 2016, Nov-23, Volume: 64, Issue:46

    Topics: Animals; Biflavonoids; Catechin; Cytokines; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Liver; Male; Malus; Mice; Mice, Inbred C57BL; Plant Extracts; Proanthocyanidins

2016
Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Feb-15, Volume: 18, Issue:4

    Topics: Animals; Antioxidants; Biflavonoids; Blood Glucose; Catechin; Cinnamomum aromaticum; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Phytotherapy; Plant Bark; Plant Extracts; Plants, Medicinal; Proanthocyanidins; Streptozocin

2011
Diverse mechanisms of antidiabetic effects of the different procyanidin oligomer types of two different cinnamon species on db/db mice.
    Journal of agricultural and food chemistry, 2012, Sep-12, Volume: 60, Issue:36

    Topics: Animals; Biflavonoids; Blood Glucose; Catechin; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Male; Mice; Phytotherapy; Plant Extracts; Proanthocyanidins

2012
ncRNAs and polyphenols: new therapeutic strategies for hypertension.
    RNA biology, 2022, Volume: 19, Issue:1

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelial Cells; Genome-Wide Association Study; Hypertension; Hypoxia; MicroRNAs; NF-kappa B; Nitric Oxide; Phosphatidylinositol 3-Kinases; Polyphenols; Proanthocyanidins; Rats; Rats, Inbred SHR; RNA, Long Noncoding

2022
Peanut skin procyanidins ameliorate insulin resistance via modulation of gut microbiota and gut barrier in type 2 diabetic mice.
    Journal of the science of food and agriculture, 2022, Volume: 102, Issue:13

    Topics: Animals; Arachis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Insulin Resistance; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Proanthocyanidins

2022
Insoluble-Bound Polyphenols Released from Guarana Powder: Inhibition of Alpha-Glucosidase and Proanthocyanidin Profile.
    Molecules (Basel, Switzerland), 2020, Feb-05, Volume: 25, Issue:3

    Topics: alpha-Glucosidases; Brazil; Caffeine; Diabetes Mellitus, Type 2; Dietary Supplements; Glycoside Hydrolase Inhibitors; Humans; Medicine, Traditional; Paullinia; Phytochemicals; Plant Extracts; Polyphenols; Proanthocyanidins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Theobromine; Theophylline

2020
Adding value to polyvinylpolypyrrolidone winery residue: A resource of polyphenols with neuroprotective effects and ability to modulate type 2 diabetes-relevant enzymes.
    Food chemistry, 2020, Nov-01, Volume: 329

    Topics: Acetylcholinesterase; Aldehyde Reductase; Animals; Antioxidants; Cell Line; Diabetes Mellitus, Type 2; Glutamic Acid; Glycoside Hydrolase Inhibitors; GPI-Linked Proteins; Humans; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidation-Reduction; Plant Extracts; Polyphenols; Povidone; Proanthocyanidins; Rats; Wine

2020
Characteristics of the interaction mechanisms of procyanidin B1 and procyanidin B2 with protein tyrosine phosphatase-1B: Analysis by kinetics, spectroscopy methods and molecular docking.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2021, Oct-05, Volume: 259

    Topics: Biflavonoids; Catechin; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Kinetics; Molecular Docking Simulation; Proanthocyanidins; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Spectrum Analysis

2021
Analysis of anti-obesity and anti-diabetic effects of acacia bark-derived proanthocyanidins in type 2 diabetes model KKAy mice.
    Journal of natural medicines, 2021, Volume: 75, Issue:4

    Topics: Acacia; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Mice; Obesity; Plant Bark; Proanthocyanidins

2021
The stabilizing effect of an oligomeric proanthocyanidin on red blood cell membrane structure of poorly controlled Type II diabetes.
    Nutrition & diabetes, 2017, May-15, Volume: 7, Issue:5

    Topics: Aged; Diabetes Mellitus, Type 2; Elasticity; Erythrocyte Deformability; Erythrocyte Membrane; Erythrocytes; Female; Humans; Male; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Pinus; Plant Extracts; Proanthocyanidins

2017
Proanthocyanidins are the major anti-diabetic components of cinnamon water extract.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 56

    Topics: Cinnamomum zeylanicum; Circular Dichroism; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Plant Extracts; Proanthocyanidins; Protein Structure, Secondary; Water

2013
Functional and morphological effects of grape seed proanthocyanidins on peripheral neuropathy in rats with type 2 diabetes mellitus.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:7

    Topics: Adenosine Triphosphatases; Animals; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Grape Seed Extract; Male; Neural Conduction; Pain Threshold; Peripheral Nervous System Diseases; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Streptozocin

2014
Dietary intakes of individual flavanols and flavonols are inversely associated with incident type 2 diabetes in European populations.
    The Journal of nutrition, 2014, Volume: 144, Issue:3

    Topics: Adult; Diabetes Mellitus, Type 2; Diet; Europe; Female; Flavonoids; Flavonols; Follow-Up Studies; Humans; Incidence; Life Style; Male; Middle Aged; Motor Activity; Multivariate Analysis; Nutritional Status; Proanthocyanidins; Proportional Hazards Models; Prospective Studies; Risk Factors; Socioeconomic Factors; Surveys and Questionnaires; White People

2014
Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:7

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Endoplasmic Reticulum Stress; Grape Seed Extract; Male; Proanthocyanidins; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve

2014
Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats.
    Molecular medicine reports, 2015, Volume: 11, Issue:1

    Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Catalase; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glycated Hemoglobin; Grape Seed Extract; Insulin; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; Malondialdehyde; Matrix Metalloproteinase 9; Proanthocyanidins; Rats; Streptozocin; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha

2015
Anti-inflammatory effects of grape seed procyanidin B2 on a diabetic pancreas.
    Food & function, 2015, Volume: 6, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antigens, Surface; Biflavonoids; Carrier Proteins; Catechin; Diabetes Mellitus, Type 2; Humans; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Milk Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreas; Plant Extracts; Proanthocyanidins; Seeds; Vitis

2015
Preventive effects of procyanidin A2 on glucose homeostasis, pancreatic and duodenal homebox 1, and glucose transporter 2 gene expression disturbance induced by bisphenol A in male mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:2

    Topics: Animals; Apoptosis; Benzhydryl Compounds; Blood Glucose; Catechin; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 2; Homeodomain Proteins; Homeostasis; Hyperglycemia; Insulin; Islets of Langerhans; Male; Malondialdehyde; Mice; Phenols; Proanthocyanidins; RNA, Messenger; Trans-Activators

2016
Effects of proanthocyanidin preparations on hyperlipidemia and other biomarkers in mouse model of type 2 diabetes.
    Journal of agricultural and food chemistry, 2008, Sep-10, Volume: 56, Issue:17

    Topics: Animals; Cholesterol; Diabetes Mellitus, Type 2; Hyperglycemia; Hyperlipidemias; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Proanthocyanidins; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Triglycerides

2008
A convenient synthesis of Type A procyanidins.
    Molecules (Basel, Switzerland), 2009, Feb-17, Volume: 14, Issue:2

    Topics: Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Humans; Molecular Structure; Plant Extracts; Proanthocyanidins; Salts

2009
Cinchonain Ib isolated from Eriobotrya japonica induces insulin secretion in vitro and in vivo.
    Journal of ethnopharmacology, 2009, Jul-15, Volume: 124, Issue:2

    Topics: Administration, Oral; Animals; Biflavonoids; Blood Glucose; Catechin; Catechols; Cell Line; Chlorogenic Acid; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Eriobotrya; Female; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Plant Extracts; Plant Leaves; Proanthocyanidins; Pyrones; Rats; Rats, Wistar

2009
Grape seed-derived procyanidins decrease dipeptidyl-peptidase 4 activity and expression.
    Journal of agricultural and food chemistry, 2012, Sep-12, Volume: 60, Issue:36

    Topics: Animals; Blood Glucose; Caco-2 Cells; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Down-Regulation; Female; Gene Expression; Grape Seed Extract; Humans; Proanthocyanidins; Rats; Rats, Wistar; Rats, Zucker; Vitis

2012
Role of phenolics as antioxidants, biomolecule protectors and as anti-diabetic factors--evaluation on bark and empty pods of Acacia auriculiformis.
    Asian Pacific journal of tropical medicine, 2012, Volume: 5, Issue:10

    Topics: Acacia; alpha-Amylases; Antioxidants; Diabetes Mellitus, Type 2; Flavonoids; Free Radical Scavengers; Humans; Hypoglycemic Agents; Iron Chelating Agents; Oxidation-Reduction; Phenols; Phytotherapy; Plant Bark; Plant Extracts; Plant Preparations; Proanthocyanidins

2012
Cinnamtannin B-1 from bay wood reduces abnormal intracellular Ca2+ homeostasis and platelet hyperaggregability in type 2 diabetes mellitus patients.
    Archives of biochemistry and biophysics, 2007, Jan-15, Volume: 457, Issue:2

    Topics: Anthocyanins; Antioxidants; Blood Platelets; Calcium; Calcium Signaling; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Homeostasis; Humans; In Vitro Techniques; Laurus; Plant Preparations; Platelet Aggregation; Proanthocyanidins; Reactive Oxygen Species

2007