Page last updated: 2024-09-02

procyanidin and Colorectal Cancer

procyanidin has been researched along with Colorectal Cancer in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's13 (56.52)24.3611
2020's5 (21.74)2.80

Authors

AuthorsStudies
Bianca Xu, G; Chen, H; Chitrakar, B; Gao, Z; Han, X; Lin, X; Sun, Y; Zhang, Z; Zhao, W; Zhou, K; Zhou, Q1
Oteiza, PI; Zhu, W1
Choy, YY; Cremonini, E; Fraga, M; Mackenzie, GG; Oteiza, PI; Waterhouse, AL1
Bird, AR; McInerney, JK; Noakes, M; Record, IR1
Chen, Y; Han, Z; He, X; Li, J; Liu, W; Wang, Y; Wen, J; Yang, Y; Yang, Z; Zhang, K; Zhu, W1
Adamo, AM; Alfine, E; Daveri, E; Oteiza, PI; Zhu, W1
Banwait, JK; Goel, A; Sharma, GG; Sharma, P; Shimura, T1
Ball, IA; Bowen, JM; Gibson, RJ; Keefe, DMK; Van Sebille, YZA; Wardill, HR1
Cardenas, J; Goel, A; Gu, J; Ravindranathan, P; Toden, S; Yuchang, M1
Balaji, U; Cardenas, J; Goel, A; Gu, J; Pasham, D; Ravindranathan, P; Toden, S2
Chang, H; Chiang, HC; Chou, KF; Chung, YC; Hsu, CP; Lin, CC; Lo, LT; Wang, AY1
Goel, A; Pasham, D; Ravindranathan, P1
Bazzoli, F; Belluzzi, A; Bianchi, F; D'Angelo, L; Fazio, C; Fogliano, V; Graziani, G; Montanaro, L; Munarini, A; Pacilli, A; Piazzi, G; Prossomariti, A; Ricciardiello, L1
Chung, WG; Maier, CS; Miranda, CL; Stevens, JF1
Chou, CC; Chung, YC; Hsu, CP; Hsu, YC; Ku, FM; Lin, YH; Liu, CL; Zhou, SP1
Bosetti, C; Franceschi, S; Giacosa, A; La Vecchia, C; Lagiou, P; Montella, M; Negri, E; Parpinel, M; Rossi, M; Talamini, R1
Bosetti, C; La Vecchia, C; Lagiou, P; Negri, E; Rossi, M1
Ho, CT; Lai, CS; Pan, MH; Wu, JC1
Albert, PS; Bobe, G; Cross, AJ; Lanza, E; Murphy, G; Sansbury, LB; Schatzkin, A1
Da Silva, M; Erlejman, AG; Fraga, CG; Jaggers, GK; Oteiza, PI; Verstraeten, SV1
Hamada, H; Iigo, M; Kojima, S; Nomoto, H; Tsuda, H1
Chung, JH; Kim, HK; Kim, MJ; Kim, YJ; Leem, KH; Park, HJ; Yoon, SH1

Reviews

1 review(s) available for procyanidin and Colorectal Cancer

ArticleYear
Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds.
    Molecular nutrition & food research, 2011, Volume: 55, Issue:1

    Topics: Anticarcinogenic Agents; Apoptosis; Carotenoids; Cell Differentiation; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Diet; Fatty Acids, Omega-3; Flavonoids; Humans; Inflammation; Life Style; Proanthocyanidins; Signal Transduction; Sphingolipids

2011

Trials

2 trial(s) available for procyanidin and Colorectal Cancer

ArticleYear
Chocolate consumption, fecal water antioxidant activity, and hydroxyl radical production.
    Nutrition and cancer, 2003, Volume: 47, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Antioxidants; Biflavonoids; Body Water; Cacao; Catechin; Colorectal Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Feces; Female; Flavonoids; Humans; Hydroxyl Radical; Iron; Male; Middle Aged; Phenols; Polyphenols; Proanthocyanidins

2003
Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention Trial.
    International journal of cancer, 2012, Apr-01, Volume: 130, Issue:7

    Topics: Adenoma; Aged; Colonic Polyps; Colorectal Neoplasms; Diet; Female; Humans; Lignans; Logistic Models; Male; Middle Aged; Neoplasm Recurrence, Local; Odds Ratio; Proanthocyanidins; Prospective Studies; Surveys and Questionnaires

2012

Other Studies

20 other study(ies) available for procyanidin and Colorectal Cancer

ArticleYear
Characterization of procyanidin extracts from hawthorn (Crataegus pinnatifida) in human colorectal adenocarcinoma cell line Caco-2, simulated Digestion, and fermentation identified unique and novel prebiotic properties.
    Food research international (Ottawa, Ont.), 2023, Volume: 165

    Topics: Adenocarcinoma; Caco-2 Cells; Catechin; Colorectal Neoplasms; Crataegus; Digestion; Fermentation; Humans; Proanthocyanidins

2023
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion.
    Redox biology, 2023, Volume: 65

    Topics: Caco-2 Cells; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Electrocardiography; Epidermal Growth Factor; ErbB Receptors; Humans; Matrix Metalloproteinase 2; NADPH Oxidase 1; Neoplasm Invasiveness; Proanthocyanidins

2023
The PI3K/Akt pathway is involved in procyanidin-mediated suppression of human colorectal cancer cell growth.
    Molecular carcinogenesis, 2016, Volume: 55, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biflavonoids; Caco-2 Cells; Catechin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colon; Colorectal Neoplasms; Humans; Phosphatidylinositol 3-Kinases; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Rectum; Signal Transduction

2016
Proanthocyanidins inhibited colorectal cancer stem cell characteristics through Wnt/β-catenin signaling.
    Environmental toxicology, 2023, Volume: 38, Issue:12

    Topics: Animals; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Proanthocyanidins

2023
Hexameric procyanidins inhibit colorectal cancer cell growth through both redox and non-redox regulation of the epidermal growth factor signaling pathway.
    Redox biology, 2021, Volume: 38

    Topics: Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Epidermal Growth Factor; ErbB Receptors; Humans; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Phosphorylation; Proanthocyanidins; Signal Transduction

2021
Enhanced anti-cancer activity of andrographis with oligomeric proanthocyanidins through activation of metabolic and ferroptosis pathways in colorectal cancer.
    Scientific reports, 2021, 04-06, Volume: 11, Issue:1

    Topics: Andrographis; Animals; Antioxidants; Apoptosis; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; Diterpenes; Drug Therapy, Combination; Ferroptosis; Humans; Male; Mice; Mice, Nude; Organoids; Plant Extracts; Proanthocyanidins; Xenograft Model Antitumor Assays

2021
Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer.
    International journal of cancer, 2018, 01-15, Volume: 142, Issue:2

    Topics: Animals; Cell Membrane Permeability; Chlorides; Colorectal Neoplasms; Diarrhea; Electrophysiology; Gastrointestinal Tract; Humans; Male; Proanthocyanidins; Quinazolinones; Rats; Rats, Wistar; Tumor Cells, Cultured; Weight Loss

2018
Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer.
    Scientific reports, 2018, 02-20, Volume: 8, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Colorectal Neoplasms; Humans; Male; Mice; Mice, Nude; Neoplastic Stem Cells; Organoids; Proanthocyanidins; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2018
Mechanistic insights into anticancer properties of oligomeric proanthocyanidins from grape seeds in colorectal cancer.
    Carcinogenesis, 2018, 05-28, Volume: 39, Issue:6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; DNA Replication; Grape Seed Extract; HCT116 Cells; HT29 Cells; Humans; Male; Mice; Mice, Nude; Proanthocyanidins; Seeds; Vitis

2018
Longan flower proanthocyanidins induce apoptosis in HT-29 colorectal carcinoma spheroids.
    Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Colorectal Neoplasms; ErbB Receptors; Flowers; Humans; Phosphorylation; Plant Extracts; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Sapindaceae; Spheroids, Cellular; Tumor Cells, Cultured

2018
A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer.
    Scientific reports, 2018, 09-14, Volume: 8, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Curcumin; Drug Interactions; Endoplasmic Reticulum Chaperone BiP; Humans; Mice; Organoids; Polymerization; Proanthocyanidins; Safety; Xenograft Model Antitumor Assays

2018
Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells.
    Carcinogenesis, 2019, 05-14, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; HCT116 Cells; Humans; Male; Mice; Mice, Nude; Oxaliplatin; Polymers; Proanthocyanidins; Xenograft Model Antitumor Assays

2019
A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells.
    Carcinogenesis, 2014, Volume: 35, Issue:10

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Eicosapentaenoic Acid; Grape Seed Extract; Humans; Proanthocyanidins; Proto-Oncogene Proteins c-myc; Signal Transduction; TOR Serine-Threonine Kinases

2014
Hop proanthocyanidins induce apoptosis, protein carbonylation, and cytoskeleton disorganization in human colorectal adenocarcinoma cells via reactive oxygen species.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:4

    Topics: Adenocarcinoma; Amino Acid Sequence; Anticarcinogenic Agents; Apoptosis; Cell Survival; Colorectal Neoplasms; Cytoskeleton; Glutathione; HT29 Cells; Humans; Humulus; Hydrogen Peroxide; Molecular Sequence Data; Proanthocyanidins; Protein Carbonylation; Reactive Oxygen Species

2009
Mechanisms of grape seed procyanidin-induced apoptosis in colorectal carcinoma cells.
    Anticancer research, 2009, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Collagen Type XI; Colorectal Neoplasms; Grape Seed Extract; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Plant Extracts; Proanthocyanidins; Proto-Oncogene Proteins c-bcl-2

2009
Proanthocyanidins and the risk of colorectal cancer in Italy.
    Cancer causes & control : CCC, 2010, Volume: 21, Issue:2

    Topics: Adult; Aged; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Incidence; Italy; Male; Middle Aged; Odds Ratio; Proanthocyanidins; Risk Assessment; Surveys and Questionnaires

2010
Flavonoids, proanthocyanidins, and cancer risk: a network of case-control studies from Italy.
    Nutrition and cancer, 2010, Volume: 62, Issue:7

    Topics: Breast Neoplasms; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Flavonoids; Humans; Italy; Kidney Neoplasms; Logistic Models; Neoplasms; Odds Ratio; Proanthocyanidins

2010
Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells.
    Free radical biology & medicine, 2012, Jan-01, Volume: 52, Issue:1

    Topics: Antioxidants; Apoptosis; Bile; Caco-2 Cells; Calcium; Cell Membrane; Cell Survival; Colorectal Neoplasms; Deoxycholic Acid; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oxidants; p38 Mitogen-Activated Protein Kinases; Polymerization; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Signal Transduction

2012
Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis.
    Nutrition and cancer, 2004, Volume: 49, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Azoxymethane; Biflavonoids; Carcinogens; Caspase 3; Caspases; Catechin; Cell Division; Colorectal Neoplasms; Immunohistochemistry; Male; Proanthocyanidins; Random Allocation; Rats; Rats, Inbred F344

2004
Anticancer effects of oligomeric proanthocyanidins on human colorectal cancer cell line, SNU-C4.
    World journal of gastroenterology, 2005, Aug-14, Volume: 11, Issue:30

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Base Sequence; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Line, Tumor; Colorectal Neoplasms; DNA, Complementary; Genes, bcl-2; Humans; Proanthocyanidins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Neoplasm

2005