procyanidin has been researched along with Alloxan Diabetes in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (28.57) | 29.6817 |
| 2010's | 30 (61.22) | 24.3611 |
| 2020's | 5 (10.20) | 2.80 |
| Authors | Studies |
|---|---|
| Li, S; Li, X; Sui, Y; Sun, Z; Xie, B | 1 |
| Li, X; Sui, Y; Sun, Z; Wu, Q; Xie, B | 1 |
| Ardevol, A; Arola, L; Blay, M; Casanova-Marti, A; Gonzalez-Abuin, N; Pinent, M | 1 |
| Huang, C; Jia, Q; Li, Y; Lu, Z; Wang, R; Wu, X; Wu, Y | 1 |
| Azay, J; Cros, G; Gasc, F; Jenin, C; Krosniak, M; Landrault, N; Poucheret, P; Teissedre, PL | 1 |
| Ardévol, A; Arola, L; Bladé, MC; Blay, M; Pinent, M; Salvadó, MJ | 1 |
| Bayram, S; Cerkezkayabekir, A; Ersoy, O; Karaca, T; Kizilay, G; Sapmaz-Metin, M | 1 |
| Huang, B; Liu, M; Liu, R; Lu, Q; Wang, L | 1 |
| Ju, T; Liu, M; Liu, R; Lu, Q; Shen, J; Willing, BP; Wu, X; Zhu, X | 1 |
| Lai, B; Liu, J; Ma, W; Nie, X; Qian, L; Tian, Y; Wang, N; Xiao, L; Xie, X; Yang, C; Yao, Q | 1 |
| Du, X; Fu, X; Hou, Y; Huang, Z; Li, J; Luo, Y; Zhuan, Q | 1 |
| Cai, Q; Cheng, M; Gao, H; Li, B; Lu, W; Qin, W; Wang, H; Yin, M; Yu, F; Zhang, P; Zhang, Z | 1 |
| Cheng, L; Gu, Z; Hong, Y; Ji, N; Li, C; Li, Z | 1 |
| Cui, S; Diao, F; Dong, Y; Du, M; Ji, Y; Kong, L; Lu, H; Ren, X; Wang, N; Yang, K; Zhang, C | 1 |
| Gao, H; Gao, Z; Hu, Z; Jiang, B; Li, B; Li, X; Peng, T; Yang, X | 1 |
| Chen, S; Duan, H; Hou, B; Li, F; Shi, Y; Wei, J; Wu, H; Zhang, H; Zhao, L | 1 |
| Balci Yuce, H; Elmastas, M; Gevrek, F; Lektemur Alpan, A; Toker, H | 1 |
| Chen, B; Gao, Z; Hu, Z; Li, X; Liu, G; Shi, W; Zou, P | 1 |
| B K, CS; Devi, SA; Muthangi, S; Sanna, RS | 1 |
| Cai, Q; Cheng, M; Gao, HQ; Li, BY; Li, XL; Lu, WD; Shen, L; Wang, JF; Yu, F; Zhang, Z; Zhou, RH | 1 |
| Akileshwari, C; Muthenna, P; Raghu, G; Reddy, GB; Sinha, SN; Suryanarayana, P | 1 |
| Akita, M; Fujita, K; Furumoto, T; Hamada, K; Inami, Y; Kaneda, Y; Kitamura, K; Maeda, A; Nakaoji, K; Ozawa, N; Sahara, S; Tamai, K; Toyoshima, M; Zaiki, K | 1 |
| Krueger, CG; Kuhn, P; Lila, MA; Moskal, K; Raskin, I; Roopchand, DE | 1 |
| Dai, X; Ding, Y; Jiang, Y; Li, Y; Zhang, Z | 1 |
| Cai, X; Dai, X; Ding, Y; Jiang, Y; Li, Y; Ma, X; Zhang, Z | 1 |
| Bao, L; Cai, X; Dai, X; Ding, Y; Jiang, Y; Li, Y; Zhang, Z | 1 |
| Bao, L; Dai, X; Ding, Y; Jiang, Y; Li, Y; Zhang, Z | 1 |
| Chen, S; Gao, Z; Jiang, X; Li, B; Liu, Z; Meng, L; Shi, B; Yang, Y; Zhang, D; Zhang, Z; Zhu, Y | 1 |
| Fujita, K; Hamada, K; Kaneda, Y; Kuge, K; Maeda, A; Nakaoji, K; Ozawa, N; Sahara, S; Takenaka, Y; Tamai, K; Tanahashi, T; Zaiki, K | 1 |
| Li, Y; Zhang, Z | 1 |
| Morazzoni, P; Pinna, C; Sala, A | 1 |
| Cui, XP; Gao, HQ; Li, BY; Lu, M; Wang, WL; Wei, N | 1 |
| Cheng, M; Gao, HQ; Li, BY; Li, M; Li, XH; Li, XL; Ma, YB; Xu, L | 1 |
| Ardévol, A; Arola, L; Bladé, C; Blay, M; Fernández-Larrea, J; Puiggròs, F; Pujadas, G; Sala, E; Salvadó, MJ; Vaqué, M | 1 |
| Cheng, M; Gao, HQ; Li, BY; Li, XH; Li, XL; Ma, YB; Xu, L | 1 |
| Cheng, M; Gao, HQ; Hu, JW; Li, BY; Li, XH; Li, XL; Xu, L; Zhang, WD | 1 |
| Cui, X; Feng, H; Gao, H; Li, B; Lu, M; Xu, L; Zhang, C; Zhang, W | 1 |
| Barışkaner, H; Baysal, H; Belviranlı, M; Gökbel, H; Okudan, N; Sahin, AS | 1 |
| Sayed, AA | 1 |
| Bao, L; Cai, X; Dai, X; Ding, Y; Gu, J; Jiang, Y; Jing, L; Li, Y; Ma, X; Zhang, F; Zhang, Z | 1 |
| Cai, Q; Cheng, M; Gao, HQ; Li, BY; Li, XL; Lu, WD; Wang, JF; Yin, M; Yu, F; Zhang, JH; Zhang, Z; Zhou, RH | 1 |
| Natsume, M; Osakabe, N; Osawa, T; Yamagishi, M; Yasuda, A | 1 |
| Ahmed, AA; El-Alfy, AT; Fatani, AJ | 1 |
| Liu, YN; Shen, XN; Yao, GY | 1 |
| Inoue, K; Ohwatari, T; Osakabe, N; Takano, H; Tomaru, M; Uematsu, H; Yanagisawa, R; Yasuda, A | 1 |
| Cho, EJ; Kim, YJ; Lee, YA; Yokozawa, T | 1 |
| Cheng, M; Gao, HQ; Li, BY; Li, XH; Xu, L; Zhang, H | 1 |
| Cheng, M; Gao, HQ; Li, BY; Li, XH; Li, XL; Ma, YB; Xu, L; You, BA | 1 |
| Cheng, M; Gao, H; Li, B; Pan, J; Xu, L; Zhang, C; Zhang, W | 1 |
1 review(s) available for procyanidin and Alloxan Diabetes
| Article | Year |
|---|---|
Procyanidins and their healthy protective effects against type 2 diabetes.
Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Proanthocyanidins | 2015 |
48 other study(ies) available for procyanidin and Alloxan Diabetes
| Article | Year |
|---|---|
Diabetes diminishes a typical metabolite of litchi pericarp oligomeric procyanidins (LPOPC) in urine mediated by imbalanced gut microbiota.
Topics: Animals; Antioxidants; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fasting; Fruit; Gastrointestinal Microbiome; Litchi; Male; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; RNA, Ribosomal, 16S | 2021 |
Attenuated mTOR Signaling and Enhanced Glucose Homeostasis by Dietary Supplementation with Lotus Seedpod Oligomeric Procyanidins in Streptozotocin (STZ)-Induced Diabetic Mice.
Topics: Animals; Biflavonoids; Blood Glucose; Catechin; Diabetes Mellitus, Experimental; Dietary Supplements; Homeostasis; Humans; Insulin; Male; Mice; Mice, Inbred ICR; Nelumbo; Plant Extracts; Proanthocyanidins; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
Hypoglycemic activities of A- and B-type procyanidin oligomer-rich extracts from different Cinnamon barks.
Topics: Animals; Antioxidants; Biflavonoids; Blood Glucose; Catechin; Cinnamomum aromaticum; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Hep G2 Cells; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Phytotherapy; Plant Bark; Plant Extracts; Plants, Medicinal; Proanthocyanidins; Streptozocin | 2011 |
Effect of a polyphenols-enriched chardonnay white wine in diabetic rats.
Topics: Animals; Anthocyanins; Antioxidants; Biflavonoids; Caffeic Acids; Catechin; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Flavonoids; Gallic Acid; Male; Mesenteric Arteries; Oxidative Stress; Phenols; Polymers; Proanthocyanidins; Rats; Rats, Wistar; Tannins; Wine | 2003 |
Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Disease Models, Animal; Glucose; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Muscle Fibers, Skeletal; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Vitis | 2004 |
Role of JNK, TGF-β1, Akt, IL-1β and INSL-3 in proanthocyanidin protection against apoptosis in diabetic rat testis.
Topics: Animals; Antioxidants; Apoptosis; Diabetes Mellitus, Experimental; Interleukin-1beta; Male; Oxidative Stress; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Streptozocin; Testis; Transforming Growth Factor beta1 | 2022 |
Peanut skin procyanidins ameliorate insulin resistance via modulation of gut microbiota and gut barrier in type 2 diabetic mice.
Topics: Animals; Arachis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Insulin Resistance; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Proanthocyanidins | 2022 |
Peanut skin procyanidins reduce intestinal glucose transport protein expression, regulate serum metabolites and ameliorate hyperglycemia in diabetic mice.
Topics: Animals; Arachis; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Transport Proteins, Facilitative; Hyperglycemia; Proanthocyanidins | 2023 |
Procyanidin B2 Activates PPARγ to Induce M2 Polarization in Mouse Macrophages.
Topics: Animals; Anti-Inflammatory Agents; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; HEK293 Cells; Humans; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Proanthocyanidins; RAW 264.7 Cells | 2019 |
Procyanidin B2 Improves Oocyte Maturation and Subsequent Development in Type 1 Diabetic Mice by Promoting Mitochondrial Function.
Topics: Animals; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Mitochondria; Oocytes; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species; Streptozocin | 2020 |
Grape seed procyanidin B2 ameliorates hepatic lipid metabolism disorders in db/db mice.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Antioxidants; Biflavonoids; Catechin; Diabetes Complications; Diabetes Mellitus, Experimental; Enzyme Activation; Grape Seed Extract; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Proanthocyanidins | 2017 |
Binary and Tertiary Complex Based on Short-Chain Glucan and Proanthocyanidins for Oral Insulin Delivery.
Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Delivery Systems; Glucans; Humans; Hypoglycemic Agents; Insulin; Male; Proanthocyanidins; Rats; Rats, Wistar | 2017 |
Thioredoxin is implicated in the anti‑apoptotic effects of grape seed proanthocyanidin extract during hyperglycemia.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Line, Tumor; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disulfides; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation; Grape Seed Extract; Heat-Shock Proteins; Hyperglycemia; Hypoglycemic Agents; Imidazoles; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Oxidative Stress; Proanthocyanidins; Signal Transduction; Streptozocin; Thioredoxins | 2017 |
Nephrin loss is reduced by grape seed proanthocyanidins in the experimental diabetic nephropathy rat model.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Glycation End Products, Advanced; Grape Seed Extract; Humans; Kidney; Membrane Proteins; Oxidative Stress; Proanthocyanidins; Rats; Receptor for Advanced Glycation End Products | 2017 |
Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice.
Topics: Albuminuria; Animals; Anthocyanins; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Body Weight; Carrier Proteins; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Fasting; Glucose; Glucosides; Grape Seed Extract; Humans; Kidney Tubules; Male; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Oxidative Stress; Phosphorylation; Proanthocyanidins; Reactive Oxygen Species; Thioredoxins; Triglycerides; Urea | 2018 |
Morphometric and histopathological evaluation of the effect of grape seed proanthocyanidin on alveolar bone loss in experimental diabetes and periodontitis.
Topics: Alveolar Bone Loss; Alveolar Process; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Grape Seed Extract; Hypoxia-Inducible Factor 1; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Ligation; Male; Matrix Metalloproteinase 8; Osteoblasts; Osteoclasts; Periodontitis; Proanthocyanidins; Rats; Rats, Wistar; Streptozocin; Tartrate-Resistant Acid Phosphatase; Vascular Endothelial Growth Factor A | 2018 |
Grape seed proanthocyanidins protect against streptozotocin‑induced diabetic nephropathy by attenuating endoplasmic reticulum stress‑induced apoptosis.
Topics: Albumins; Animals; Antioxidants; Apoptosis; Blood Glucose; Blood Urea Nitrogen; Caspase 12; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Administration Schedule; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epithelial Cells; Gastric Absorption; Gene Expression Regulation; Grape Seed Extract; Heat-Shock Proteins; Humans; Kidney; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Streptozocin | 2018 |
Grape seed proanthocyanidin extract and insulin prevents cognitive decline in type 1 diabetic rat by impacting Bcl-2 and Bax in the prefrontal cortex.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Grape Seed Extract; Insulin; Male; Neurons; Prefrontal Cortex; Proanthocyanidins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Spatial Learning; Spatial Memory | 2019 |
Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy.
Topics: Animals; Antigens, Surface; Biflavonoids; Catechin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Grape Seed Extract; Kidney; Male; MAP Kinase Signaling System; Mice; Milk Proteins; Mitogen-Activated Protein Kinase 3; Proanthocyanidins; Proteomics; Proto-Oncogene Proteins c-akt; Up-Regulation | 2013 |
Inhibition of protein glycation by procyanidin-B2 enriched fraction of cinnamon: delay of diabetic cataract in rats.
Topics: Animals; Biflavonoids; Blood Glucose; Cataract; Catechin; Cinnamomum zeylanicum; Diabetes Complications; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Humans; Lens, Crystalline; Male; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar | 2013 |
Mallotus philippinensis bark extracts promote preferential migration of mesenchymal stem cells and improve wound healing in mice.
Topics: Animals; Chemotactic Factors; Chemotaxis; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Leukocytes, Mononuclear; Mallotus Plant; Mesenchymal Stem Cells; Mice; Phytotherapy; Plant Bark; Plant Extracts; Proanthocyanidins; Wound Healing; Wounds and Injuries | 2014 |
Concord grape pomace polyphenols complexed to soy protein isolate are stable and hypoglycemic in diabetic mice.
Topics: Animals; Blood Glucose; Chemical Fractionation; Diabetes Mellitus, Experimental; Drug Stability; Hyperglycemia; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Polyphenols; Proanthocyanidins; Soybean Proteins; Vitis | 2013 |
Functional and morphological effects of grape seed proanthocyanidins on peripheral neuropathy in rats with type 2 diabetes mellitus.
Topics: Adenosine Triphosphatases; Animals; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Grape Seed Extract; Male; Neural Conduction; Pain Threshold; Peripheral Nervous System Diseases; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Streptozocin | 2014 |
Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Endoplasmic Reticulum Stress; Grape Seed Extract; Male; Proanthocyanidins; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve | 2014 |
Grape seed proanthocyanidin extracts ameliorate podocyte injury by activating peroxisome proliferator-activated receptor-γ coactivator 1α in low-dose streptozotocin-and high-carbohydrate/high-fat diet-induced diabetic rats.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Carbohydrates; DNA, Mitochondrial; Grape Seed Extract; Male; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Podocytes; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Streptozocin; Transcription Factors | 2014 |
Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Catalase; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Glycated Hemoglobin; Grape Seed Extract; Insulin; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; Malondialdehyde; Matrix Metalloproteinase 9; Proanthocyanidins; Rats; Streptozocin; Superoxide Dismutase; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2015 |
Grape Seed Proanthocyanidin Extract Ameliorates Diabetic Bladder Dysfunction via the Activation of the Nrf2 Pathway.
Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Experimental; Female; Grape Seed Extract; NF-E2-Related Factor 2; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Signal Transduction; Urinary Bladder | 2015 |
Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice.
Topics: Animals; Cell Line; Cell Movement; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Flavonoids; Male; Mesenchymal Stem Cells; Mice; Polyphenols; Proanthocyanidins; Wound Healing | 2015 |
Grape seed proanthocyanidin extracts prevent hyperglycemia-induced monocyte adhesion to aortic endothelial cells and ameliorates vascular inflammation in high-carbohydrate/high-fat diet and streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Carotid Intima-Media Thickness; Cell Adhesion; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Carbohydrates; Endothelial Cells; Glycation End Products, Advanced; Grape Seed Extract; Hyperglycemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Monocytes; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Streptozocin; Vascular Cell Adhesion Molecule-1 | 2015 |
Proanthocyanidins from Vitis vinifera inhibit oxidative stress-induced vascular impairment in pulmonary arteries from diabetic rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Diabetes Complications; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Grape Seed Extract; Male; Nitric Oxide Donors; Nitroprusside; Oxidative Stress; Phytotherapy; Proanthocyanidins; Pulmonary Artery; Rats, Sprague-Dawley; Vasodilation; Vitis | 2017 |
Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Grape Seed Extract; Male; Oxidative Stress; Pain Threshold; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Sciatic Nerve; Vitis | 2008 |
A novel approach of proteomics to study the mechanism of action of grape seed proanthocyanidin extracts on diabetic retinopathy in rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electrophoresis, Gel, Two-Dimensional; Glycated Hemoglobin; Glycation End Products, Advanced; Grape Seed Extract; Male; Plant Extracts; Proanthocyanidins; Proteomics; Rats; Rats, Wistar | 2008 |
In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.
Topics: Animals; Binding Sites; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Liver; Male; Models, Molecular; Oxidative Stress; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seeds; Superoxide Dismutase; Vitis | 2009 |
Effects of grape seed proanthocyanidin extracts on aortic pulse wave velocity in streptozocin induced diabetic rats.
Topics: Animals; Aorta; Body Weight; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Immunohistochemistry; Microscopy, Electron; Plant Extracts; Proanthocyanidins; Rats; Seeds; Streptozocin; Vitis | 2009 |
Proteomics approach to study the mechanism of action of grape seed proanthocyanidin extracts on arterial remodeling in diabetic rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Glycation End Products, Advanced; Grape Seed Extract; Male; Muscle, Smooth, Vascular; Proanthocyanidins; Proteins; Proteomics; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
Protective effects of grape seed proanthocyanidin extracts on cerebral cortex of streptozotocin-induced diabetic rats through modulating AGEs/RAGE/NF-kappaB pathway.
Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Brain Diseases, Metabolic; Cerebral Cortex; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Grape Seed Extract; Intercellular Adhesion Molecule-1; Male; NF-kappa B; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Streptozocin; Vascular Cell Adhesion Molecule-1 | 2010 |
The effect of supplementation of grape seed proanthocyanidin extract on vascular dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Grape Seed Extract; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Nitroprusside; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2011 |
Thymoquinone and proanthocyanidin attenuation of diabetic nephropathy in rats.
Topics: Animals; Benzoquinones; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Therapy, Combination; Glutathione; Interleukin-6; Lipid Peroxidation; Male; Proanthocyanidins; Rats; Streptozocin | 2012 |
Grape seed proanthocyanidin extracts alleviate oxidative stress and ER stress in skeletal muscle of low-dose streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Carbohydrates; Endoplasmic Reticulum Stress; Grape Seed Extract; Male; Muscle, Skeletal; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Streptozocin | 2013 |
Proteomic analysis of aorta and protective effects of grape seed procyanidin B2 in db/db mice reveal a critical role of milk fat globule epidermal growth factor-8 in diabetic arterial damage.
Topics: Aged; Animals; Antigens, Surface; Aorta; Biflavonoids; Blood Glucose; Body Weight; Cardiotonic Agents; Catechin; Cholesterol; Computational Biology; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Fasting; Glycation End Products, Advanced; Grape Seed Extract; Humans; Isotope Labeling; Male; Mice; Mice, Inbred C57BL; Milk Proteins; Proanthocyanidins; Proteome; Proteomics; RNA Interference; Triglycerides | 2012 |
Ingestion of proanthocyanidins derived from cacao inhibits diabetes-induced cataract formation in rats.
Topics: Aldehydes; Amidines; Animal Feed; Animals; Blood Glucose; Body Weight; Cacao; Cataract; Diabetes Mellitus, Experimental; Fructosamine; Immunohistochemistry; Lipid Peroxides; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2004 |
Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats.
Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Insulin; Lipid Peroxidation; Male; Nitrates; Nitrites; Pancreas; Proanthocyanidins; Rats; Rats, Wistar; Seeds; Vitis | 2005 |
[Effects of grape seed proanthocyanidins extracts on experimental diabetic nephropathy in rats].
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Kidney Function Tests; Male; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Vitis | 2006 |
Dietary supplementation with cacao liquor proanthocyanidins prevents elevation of blood glucose levels in diabetic obese mice.
Topics: Aging; Animals; Blood Glucose; Body Weight; Cacao; Diabetes Mellitus, Experimental; Dietary Supplements; Dose-Response Relationship, Drug; Fructosamine; Hyperglycemia; Hypoglycemic Agents; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Postprandial Period; Proanthocyanidins | 2007 |
Ameliorative effects of proanthocyanidin on oxidative stress and inflammation in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diospyros; Fruit; Glutathione; Inflammation; Kidney; Lipid Peroxidation; Male; Oxidative Stress; Proanthocyanidins; Rats; Rats, Wistar | 2007 |
Cardioprotective effects of grape seed proanthocyanidins extracts in streptozocin induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Cardiomyopathies; Cardiotonic Agents; Diabetes Mellitus, Experimental; Gene Expression; Glycated Hemoglobin; Glycation End Products, Advanced; Grape Seed Extract; Heart; Male; Microscopy, Electron; Mitochondria; Myocardium; NF-kappa B; Organ Size; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta1 | 2007 |
Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy.
Topics: Amino Acids; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Down-Regulation; Feedback, Physiological; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Grape Seed Extract; Oxidative Stress; Plant Extracts; Proanthocyanidins; Proteins; Proteomics; Rats; Up-Regulation | 2008 |
Oral administration of grape seed proanthocyanidin extracts downregulate RAGE dependant nuclear factor- kappa BP65 expression in the hippocampus of streptozotocin induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; DNA Primers; Gene Expression Regulation; Hippocampus; Male; Plant Extracts; Proanthocyanidins; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Seeds; Transcription Factor RelA; Vitis | 2008 |