prochlorperazine has been researched along with Vomiting in 151 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prophylactic prochlorperazine seems to be ineffective in preventing opioid-induced nausea and vomiting (OINV) and may cause adverse events such as somnolence." | 9.27 | Efficacy of Prophylactic Treatment for Oxycodone-Induced Nausea and Vomiting Among Patients with Cancer Pain (POINT): A Randomized, Placebo-Controlled, Double-Blind Trial. ( Ando, M; Ando, Y; Gyawali, B; Hasegawa, Y; Kato, H; Kondo, M; Kubo, Y; Miyazaki, M; Morita, T; Murasaki, Y; Sugishita, M; Tsukuura, H; Yamada, K, 2018) |
| "The purpose of this article is to assess the comparative antiemetic efficacy of prochlorperazine, ondansetron, and dexamethasone in the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) after moderately high to highly emetogenic chemotherapy." | 9.11 | Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone. ( Amamoo, MA; Bernard, S; Goodin, S; Kane, M; Laliberte, K; Lindley, C; McCune, J; Pham, T; Schell, M; Shord, S; Socinski, MA; Yowell, S, 2005) |
| "Short-acting 5-HT-receptor antagonists are no better than is prochlorperazine in control of delayed nausea caused by doxorubicin." | 9.11 | 5-Hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: a URCC CCOP randomised controlled trial. ( Bole, CW; Dakhil, SR; Fitch, TR; Hickok, JT; Hoelzer, KL; Moore, T; Morrow, GR; Roscoe, JA; Zhao, H, 2005) |
| "A single-blind 8 week pilot study with random allocation to either GR 1 mg or prochlorperazine (Stemetil; PCh) 10 mg was undertaken in 13 patients who were taking or had taken MTX for either rheumatoid arthritis (10) or psoriatic arthritis (3)." | 9.09 | Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil). ( Arthur, V; Devlin, J; Emery, P; Wagstaff, K, 1999) |
| "The study was a randomized, double-blind comparison of prochlorperazine (Compazine) and promethazine (Phenergan) for acute ED treatment of gastritis or gastroenteritis." | 9.09 | Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial. ( Diercks, DB; Ernst, AA; Park, S; Takakuwa, KM; Weiss, SJ, 2000) |
| "This study has compared the incidences of nausea, vomiting and headache after ondansetron 0." | 9.08 | Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. ( van den Berg, AA, 1996) |
| "To determine the severity of emesis caused by ultra-high-dose cisplatin-carboplatin chemotherapy and to compare the antiemetic efficacy of an ondansetron regimen and a metoclopramide regimen." | 9.07 | Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy. ( Fanning, J; Hilgers, RD, 1994) |
| "We studied the efficacy and safety of intravenous ondansetron 4 mg for the prevention of postoperative nausea and vomiting after minor gynaecological laparoscopic surgery in Oriental women." | 9.07 | Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. ( Chen, PP; Critchley, LA; Gin, TA; Ray, AK; Rowbottom, YM; Suen, TK, 1994) |
| "This double-blind randomized cross-over study was conducted to compare the safety and efficacy of high-dose prochlorperazine infusion and dexamethasone (HDPD) with an effective and safe combination of high-dose metoclopramide and dexamethasone (HDMD) in controlling cisplatin-induced emesis." | 9.07 | A double-blind randomized cross-over comparison of high-dose prochlorperazine with high-dose metoclopramide for cisplatin-induced emesis. ( Akhtar, SS; Bano, ZA; Bhat, GM; Bhat, MA, 1991) |
| "The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer." | 9.06 | A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988) |
| "In a randomized, double-blind, crossover trial, nabilone was compared to prochlorperazine for control of cancer chemotherapy-induced emesis in 30 children 3." | 9.06 | Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. ( Chan, HS; Correia, JA; MacLeod, SM, 1987) |
| "Sixteen patients with acute myocardial infarctions who were either vomiting or nauseated were given an intravenous injection of prochlorperazine." | 9.06 | Intravenous prochlorperazine for the rapid control of nausea and vomiting in acute myocardial infarction: a clinical observation. ( Gilston, M; Herman, LS; Lau, JC; Ordog, GJ; Wasserberger, J, 1987) |
| "Forty patients with advanced lung cancer who had received chemotherapy containing cisplatin (80 mg/m2) were accrued for a randomized controlled trial to evaluate the additional effect of prochlorperazine on the combination of high-dose metoclopramide and dexamethasone for the treatment of acute cisplatin-induced emesis." | 9.06 | [A randomized controlled trial of acute and delayed cisplatin-induced emesis with metoclopramide, dexamethasone and prochlorperazine]. ( Eguchi, K; Inoue, I; Nino, S; Saijo, N; Sakurai, M; Sasaki, Y; Shinkai, T; Suemasu, K; Tamura, T; Umehara, H, 1987) |
| "The effectiveness of 10 mg IV prochlorperazine in preventing postoperative nausea and vomiting was compared with placebo when given perioperatively to 100 patients in a prospective double-blind randomized trial." | 9.06 | Intraoperative prochlorperazine for prevention of post-operative nausea and vomiting. ( Cramb, R; Fargas-Babjak, A; Hirano, G, 1989) |
| "Considering the prevailing concerns about extrapyramidal symptoms (EPS) associated with oral prochlorperazine, this study was conducted to assess the safety of oral prochlorperazine (in recommended dose/duration) in the management of acute dizziness." | 7.96 | The Real-World Safety and Effectiveness of Prochlorperazine in Indian Patients with Dizziness. ( A, B; Haldipur, D; Krishnamurthy, N, 2020) |
| " Delayed emesis following Cycle 1 of carboplatin was observed in 30% of patients." | 7.83 | Delayed nausea and vomiting from carboplatin doublet chemotherapy. ( Baggstrom, MQ; Chitneni, P; Gao, F; Govindan, R; Mann, J; Morgensztern, D; Waqar, MA; Waqar, SN; Williams, K, 2016) |
| "The incidence of nausea induced by oxycodone with prochlorperazine was 18." | 7.81 | Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients. ( Aoki, Y; Kanazawa, Y; Uchida, E; Yamada, T, 2015) |
| "Prochlorperazine is often used to prevent opioid-induced nausea; however, this drug causes extrapyramidal symptoms." | 7.79 | [A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction]. ( Kono, B; Kurosawa, H; Takei, D; Yomiya, K, 2013) |
| "The article reports a study comparing the cost-effectiveness of ondansetron tablets and prochlorperazine capsules in preventing nausea and vomiting after moderately emetogenic chemotherapy in an outpatient setting." | 7.70 | Cost-effectiveness analysis of oral ondansetron and prochlorperazine for preventing nausea and vomiting after moderately emetogenic chemotherapy. ( Kwong, WJ; Parasuraman, TV, 1999) |
| "A therapeutic regimen is described for sedative, analgesic, and anti-emetic effect in patients receiving intra-arterial carmustine (BCNU) for malignant gliomas." | 7.67 | Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion. ( Klein, DS; Klein, PW; Mahaley, MS, 1986) |
| "Intravenous metoclopramide and IM prochlorperazine and diazepam were compared in the management of vomiting occurring during treatment with cis-dichlorodiammineplatinum (cis-platinum)." | 7.67 | High-dose intravenous metoclopramide and intermittent intramuscular prochlorperazine and diazepam in the management of emesis induced by cis-dichlorodiammineplatinum. ( Chan, KK; Luesley, DM; Terry, PB, 1985) |
| " While prochlorperazine is effective in relieving nausea and vomiting, its low bioavailability following first pass metabolism in the liver and metabolism in the intestinal wall, compounded by the likelihood of regurgitation in the nauseous patient, may limit the therapeutic value of the oral preparation." | 6.69 | Comparison of buccal and oral prochlorperazine in the treatment of dizziness associated with nausea and/or vomiting. ( Bond, CM, 1998) |
| "Nausea and emesis are significant side effects in patients undergoing stereotactic radiosurgery for brain lesions in the region of the chemoreceptor trigger zone (area postrema of the brain)." | 6.67 | The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone. ( Alexander, E; Bodis, S; Kooy, H; Loeffler, JS, 1994) |
| "Nabilone was significantly superior to prochlorperazine in the reduction of vomiting episodes." | 6.66 | A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. ( Mattson, K; Niiranen, A, 1985) |
| " Optimal dosage and pharmacokinetic distribution of both drugs should be investigated further." | 6.66 | Comparative effects of intravenously administered alizapride and prochlorperazine in cisplatin-induced emesis. ( Desjardins, R; Ellison, R; Hyman, G; Nahas, G; Roché, H; Stoopler, M, 1987) |
| "Nausea was absent in 40 of 55 patients receiving THC, eight of 55 patients receiving prochlorperazine, and five of 55 in the placebo group." | 6.65 | Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. ( Bloome, B; McKernan, JF; Orr, LE, 1980) |
| "Metoclopramide was superior to placebo and to prochlorperazine in reducing the volume of emesis (P = 0." | 6.65 | Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting. ( Bordin, LA; Braun, DW; Braun, TJ; Gralla, RJ; Itri, LM; Kelsen, DP; Pisko, SE; Squillante, AE; Young, CW, 1981) |
| " High-dose metoclopramide has demonstrated efficacy in small series of patients in the treatment of cisplatin-induced vomiting." | 6.15 | Advances in anti-emetic therapy. ( Bakowski, MT, 1984) |
| " If no response was observed within 20 minutes, the dosage was repeated." | 5.27 | Intravenous prochlorperazine for the rapid control of vomiting in the emergency department. ( Balasubramaniam, S; Herman, LS; Ordog, GJ; Owashi, ND; Vann, PW; Wasserberger, J, 1984) |
| "Prophylactic prochlorperazine seems to be ineffective in preventing opioid-induced nausea and vomiting (OINV) and may cause adverse events such as somnolence." | 5.27 | Efficacy of Prophylactic Treatment for Oxycodone-Induced Nausea and Vomiting Among Patients with Cancer Pain (POINT): A Randomized, Placebo-Controlled, Double-Blind Trial. ( Ando, M; Ando, Y; Gyawali, B; Hasegawa, Y; Kato, H; Kondo, M; Kubo, Y; Miyazaki, M; Morita, T; Murasaki, Y; Sugishita, M; Tsukuura, H; Yamada, K, 2018) |
| "Short-acting 5-HT-receptor antagonists are no better than is prochlorperazine in control of delayed nausea caused by doxorubicin." | 5.11 | 5-Hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: a URCC CCOP randomised controlled trial. ( Bole, CW; Dakhil, SR; Fitch, TR; Hickok, JT; Hoelzer, KL; Moore, T; Morrow, GR; Roscoe, JA; Zhao, H, 2005) |
| "The purpose of this article is to assess the comparative antiemetic efficacy of prochlorperazine, ondansetron, and dexamethasone in the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) after moderately high to highly emetogenic chemotherapy." | 5.11 | Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone. ( Amamoo, MA; Bernard, S; Goodin, S; Kane, M; Laliberte, K; Lindley, C; McCune, J; Pham, T; Schell, M; Shord, S; Socinski, MA; Yowell, S, 2005) |
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| " Patients aged 18 years or older treated with prochlorperazine for headache, nausea, or vomiting were eligible for inclusion." | 5.09 | Intravenous administration of prochlorperazine by 15-minute infusion versus 2-minute bolus does not affect the incidence of akathisia: a prospective, randomized, controlled trial. ( Brizendine, EJ; Chisholm, CD; Collins, RW; Cordell, WH; Giles, BK; Jones, JB; Walthall, JD, 2001) |
| "The study was a randomized, double-blind comparison of prochlorperazine (Compazine) and promethazine (Phenergan) for acute ED treatment of gastritis or gastroenteritis." | 5.09 | Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial. ( Diercks, DB; Ernst, AA; Park, S; Takakuwa, KM; Weiss, SJ, 2000) |
| "The utility of intravenous prochlorperazine as an antiemetic agent and abortive therapy for headache may be limited by the frequent occurrence of akathisia, the distressing effects of which have been shown to disrupt patient care." | 5.09 | Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial. ( Drotts, DL; Vinson, DR, 2001) |
| "A single-blind 8 week pilot study with random allocation to either GR 1 mg or prochlorperazine (Stemetil; PCh) 10 mg was undertaken in 13 patients who were taking or had taken MTX for either rheumatoid arthritis (10) or psoriatic arthritis (3)." | 5.09 | Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil). ( Arthur, V; Devlin, J; Emery, P; Wagstaff, K, 1999) |
| "This study has compared the incidences of nausea, vomiting and headache after ondansetron 0." | 5.08 | Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. ( van den Berg, AA, 1996) |
| "Both metoclopramide and prochlorperazine in combination with lorazepam and diphenhydramine offer good control of nausea and vomiting although the sedation and low risk for cardiac toxicity limit the regimen to an inpatient setting with close monitoring." | 5.08 | Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation. ( Gilbert, CJ; Ohly, KV; Peters, WP; Rosner, G, 1995) |
| "This double-blind randomized cross-over study was conducted to compare the safety and efficacy of high-dose prochlorperazine infusion and dexamethasone (HDPD) with an effective and safe combination of high-dose metoclopramide and dexamethasone (HDMD) in controlling cisplatin-induced emesis." | 5.07 | A double-blind randomized cross-over comparison of high-dose prochlorperazine with high-dose metoclopramide for cisplatin-induced emesis. ( Akhtar, SS; Bano, ZA; Bhat, GM; Bhat, MA, 1991) |
| "The aim of this study was to determine the mechanism of action of radiation-induced emesis by determining the incidence of radiation-induced emesis following hemibody irradiation; the effects of specific antiemetics especially ondansetron, a 5-hydroxytryptamine receptor antagonist, and to determine the relationship between radiation-induced emesis and serotonin (5-hydroxytryptamine) through its active metabolite, 5-hydroxyindoleacetic acid (5-HIAA)." | 5.07 | On the mechanism of radiation-induced emesis: the role of serotonin. ( Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW, 1994) |
| "To determine the severity of emesis caused by ultra-high-dose cisplatin-carboplatin chemotherapy and to compare the antiemetic efficacy of an ondansetron regimen and a metoclopramide regimen." | 5.07 | Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy. ( Fanning, J; Hilgers, RD, 1994) |
| "We studied the efficacy and safety of intravenous ondansetron 4 mg for the prevention of postoperative nausea and vomiting after minor gynaecological laparoscopic surgery in Oriental women." | 5.07 | Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. ( Chen, PP; Critchley, LA; Gin, TA; Ray, AK; Rowbottom, YM; Suen, TK, 1994) |
| "The effectiveness of 10 mg IV prochlorperazine in preventing postoperative nausea and vomiting was compared with placebo when given perioperatively to 100 patients in a prospective double-blind randomized trial." | 5.06 | Intraoperative prochlorperazine for prevention of post-operative nausea and vomiting. ( Cramb, R; Fargas-Babjak, A; Hirano, G, 1989) |
| "In a randomized, double-blind, crossover trial, nabilone was compared to prochlorperazine for control of cancer chemotherapy-induced emesis in 30 children 3." | 5.06 | Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. ( Chan, HS; Correia, JA; MacLeod, SM, 1987) |
| "The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer." | 5.06 | A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988) |
| "Sixteen patients with acute myocardial infarctions who were either vomiting or nauseated were given an intravenous injection of prochlorperazine." | 5.06 | Intravenous prochlorperazine for the rapid control of nausea and vomiting in acute myocardial infarction: a clinical observation. ( Gilston, M; Herman, LS; Lau, JC; Ordog, GJ; Wasserberger, J, 1987) |
| "Forty patients with advanced lung cancer who had received chemotherapy containing cisplatin (80 mg/m2) were accrued for a randomized controlled trial to evaluate the additional effect of prochlorperazine on the combination of high-dose metoclopramide and dexamethasone for the treatment of acute cisplatin-induced emesis." | 5.06 | [A randomized controlled trial of acute and delayed cisplatin-induced emesis with metoclopramide, dexamethasone and prochlorperazine]. ( Eguchi, K; Inoue, I; Nino, S; Saijo, N; Sakurai, M; Sasaki, Y; Shinkai, T; Suemasu, K; Tamura, T; Umehara, H, 1987) |
| "Sixty-four patients receiving cancer chemotherapy known to induce severe emesis entered a randomized double-blind study of the antiemetic efficacy of haloperidol (Haldol) and benzquinamide (Emetecon)." | 5.05 | Specific antiemetics for specific cancer chemotherapeutic agents: haloperidol versus benzquinamide. ( Gagen, M; Neidhart, JA; Wilson, HE; Young, D, 1981) |
| "Lorazepam was compared to placebo to assess its control of nausea and vomiting in patients receiving cytotoxic chemotherapy and prochlorperazine." | 5.05 | Lorazepam: a randomized, double-blind, crossover study of a new antiemetic in patients receiving cytotoxic chemotherapy and prochlorperazine. ( Bingham, J; Bishop, JF; Cooper, IA; Hillcoat, BL; Long, M; Matthews, JP; Olver, IN; Wolf, MM, 1984) |
| "The authors tested the effectiveness of orally administered delta-9-tetrahydrocannabinol (THC) as compared to prochlorperazine for the alleviation of symptoms, such as vomiting and nausea, experienced by patients receiving radiotherapy." | 5.05 | Tetrahydrocannabinol vs. prochlorperazine. The effects of two antiemetics on patients undergoing radiotherapy. ( Andrysiak, TA; Fairbanks, LA; Parker, RG; Tesler, AS; Ungerleider, JT, 1984) |
| "Delta-9-tetrahydrocannabinol (THC) and prochlorperazine (Compazine) were found to be equally efficacious in reducing nausea and vomiting associated with cancer chemotherapy across a wide range of chemotherapeutic regimens and tumor types." | 5.05 | Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine. ( Andrysiak, T; Fairbanks, L; Goodnight, J; Jamison, K; Sarna, G; Ungerleider, JT, 1982) |
| " The incidence of nausea and vomiting in benzquinamide-treated patients was equal to that in placebo-treated patients and significantly higher than that in patients treated with prochlorperazine, 10 mg 3 times daily." | 5.04 | Oral benzquinamide in the treatment of nausea and vomiting. ( Hahn, RG; Moertel, CG; O'Fallon, JR; Schutt, AJ, 1975) |
| "The antinausea and antivomiting effects of delta-9-tetrahydrocannabinol (THC) in children receiving cancer chemotherapy were compared with those of metoclopramide syrup and prochlorperazine tablets in two double-blind studies." | 5.04 | Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol. ( Ekert, H; Jurk, IH; Loughnan, P; Mobilia, J; Waters, KD, 1979) |
| "Two double-blind, crossover trials comparing the antiemetic effectiveness of nabilone, a new synthetic cannabinoid, with that of prochlorperazine were conducted in patients with severe nausea and vomiting associated with anticancer chemotherapy." | 5.04 | Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy. ( Chester, AB; Dean, JC; Dorr, RT; Einhorn, LH; Furnas, B; Herman, TS; Jones, SE; Leigh, SA; Moon, TE; Nagy, C; Williams, SD, 1979) |
| "Prochlorperazine is recommended for adults with breakthrough or refractory chemotherapy-induced nausea and vomiting (CINV)." | 4.93 | The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis. ( Dupuis, LL; Flank, J; Lau Moon Lin, M; Robinson, PD; Sung, L, 2016) |
| "Based on the safety and efficacy of ondansetron, it may be used as a first-line agent for relief of nausea or vomiting for most patient populations in the ED." | 4.86 | Antiemetic therapy for nausea and vomiting in the emergency department. ( Amini, R; Hays, DP; Patanwala, AE; Rosen, P, 2010) |
| "Sumatriptan succinate and prochlorperazine maleate are a clinically proven combination for treating migraine and associated nausea and vomiting." | 4.12 | Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization. ( Anwer, UU; Bukhari, NI; Hafiz, MA; Hussain, A; Javed, S; Rasool, F; Raza, SA; Shah, PA; Shamim, R, 2022) |
| "Considering the prevailing concerns about extrapyramidal symptoms (EPS) associated with oral prochlorperazine, this study was conducted to assess the safety of oral prochlorperazine (in recommended dose/duration) in the management of acute dizziness." | 3.96 | The Real-World Safety and Effectiveness of Prochlorperazine in Indian Patients with Dizziness. ( A, B; Haldipur, D; Krishnamurthy, N, 2020) |
| " Delayed emesis following Cycle 1 of carboplatin was observed in 30% of patients." | 3.83 | Delayed nausea and vomiting from carboplatin doublet chemotherapy. ( Baggstrom, MQ; Chitneni, P; Gao, F; Govindan, R; Mann, J; Morgensztern, D; Waqar, MA; Waqar, SN; Williams, K, 2016) |
| "The incidence of nausea induced by oxycodone with prochlorperazine was 18." | 3.81 | Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients. ( Aoki, Y; Kanazawa, Y; Uchida, E; Yamada, T, 2015) |
| "Prochlorperazine is often used to prevent opioid-induced nausea; however, this drug causes extrapyramidal symptoms." | 3.79 | [A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction]. ( Kono, B; Kurosawa, H; Takei, D; Yomiya, K, 2013) |
| " These studies had used a conventional Long instrument in the prospective assessment of 360 adult ED patients aged 17-65 years who received intravenous prochlorperazine (10 mg) in the treatment of headache or nausea and vomiting." | 3.73 | Development of a simplified instrument for the diagnosis and grading of akathisia in a cohort of patients receiving prochlorperazine. ( Vinson, DR, 2006) |
| "The article reports a study comparing the cost-effectiveness of ondansetron tablets and prochlorperazine capsules in preventing nausea and vomiting after moderately emetogenic chemotherapy in an outpatient setting." | 3.70 | Cost-effectiveness analysis of oral ondansetron and prochlorperazine for preventing nausea and vomiting after moderately emetogenic chemotherapy. ( Kwong, WJ; Parasuraman, TV, 1999) |
| "An 11-year-old girl had a one-day history of nausea and vomiting for which her family physician prescribed 4 suppositories of prochlorperazine 25 mg." | 3.70 | [Diagnostic image (17). Acute dystonia induced by prochlorperazine]. ( van Gijn, J, 2000) |
| "Prochlorperazine is a centrally acting dopamine receptor antagonist that is most commonly used for the treatment of nausea and vomiting." | 3.69 | Tardive dyskinesia as a result of long-term prochlorperazine use. ( Alberts, VA; Catalano, G; Poole, MA, 1996) |
| "Lorazepam, dexamethasone and high-dose metoclopramide were given to 54 patients to prevent emesis induced by cisplatin (50-120 mg/m2) on day 1, while prochlorperazine and dexamethasone were administered on days 2 and 3 for control of delayed emesis." | 3.68 | Acute and delayed emesis after cisplatin-based regimen: description and prevention. ( Beaulieu, R; Courchesne, Y; Latreille, J; Letendre, F; Lorange, A; Louvet, C; Monte, M; Neemeh, JA; Pretty, HM, 1991) |
| " Major antiemetic activity was achieved in five patients, two patients had less nausea and vomiting as compared with prior prochlorperazine therapy, and three patients were refractory to droperidol." | 3.67 | The antiemetic activity of droperidol administered by intramuscular injection during cisplatin chemotherapy: a pilot study. ( Abrahamson, M; Bromer, R; Cersosimo, RJ; Hoffer, S; Hong, WK; Welch, J, 1985) |
| "Intravenous metoclopramide and IM prochlorperazine and diazepam were compared in the management of vomiting occurring during treatment with cis-dichlorodiammineplatinum (cis-platinum)." | 3.67 | High-dose intravenous metoclopramide and intermittent intramuscular prochlorperazine and diazepam in the management of emesis induced by cis-dichlorodiammineplatinum. ( Chan, KK; Luesley, DM; Terry, PB, 1985) |
| "A therapeutic regimen is described for sedative, analgesic, and anti-emetic effect in patients receiving intra-arterial carmustine (BCNU) for malignant gliomas." | 3.67 | Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion. ( Klein, DS; Klein, PW; Mahaley, MS, 1986) |
| " In 84 patients (control group), no prophylactic antiemetic or antidiarrheal drugs were administered, while in 46 patients (study group), an antiemetic (prochlorperazine) and an antidiarrheal (diphenoxylate hydrochloride with atropine sulfate) drug were administered prophylactically before and during prostaglandin infusion." | 3.66 | Prophylaxis against prostaglandin-induced gastrointestinal side effects. ( Fahmy, K, 1981) |
| " Patients received diazepam and prochlorperazine, and the incidence of vomiting and subjective evaluation of nausea were compared to previous courses of therapy with prochlorperazine alone." | 3.66 | Antiemetic effect of intravenous diazepam in patients receiving cis-diamminedichloroplatinum II: a pilot study. ( Carr, BI; Chang, YC; De Jongh, L; Drozdowicz, PM; Ershler, WB; Meyer, DK; Robins, HI, 1979) |
| "Sixty gravidas 8 to 20 menstrual weeks' gestation were studied to evaluate (1) the efficacy of intramuscularly administered 15(S)-15-methyl prostaglandin F2alpha tromethamine (15(S)-Me-PGF2alpha) as an abortifacient; (2) the effectiveness of prochlorperazine and Lomotil for attenuation of vomiting and diarrhea; and (3) the practicability of augmenting this prostaglandin dose schedule with intracervical laminaria tents." | 3.65 | Evaluation of intramuscular 15(s)-15-methyl prostaglandin F2 alpha tromethamine salt for induction of abortion, medications to attenuate side effects, and intracervical laminaria tents. ( Brenner, WE; Dingfelder, JR; Gruber, W; Staurovsky, LG; Wells, JS, 1976) |
| " While prochlorperazine is effective in relieving nausea and vomiting, its low bioavailability following first pass metabolism in the liver and metabolism in the intestinal wall, compounded by the likelihood of regurgitation in the nauseous patient, may limit the therapeutic value of the oral preparation." | 2.69 | Comparison of buccal and oral prochlorperazine in the treatment of dizziness associated with nausea and/or vomiting. ( Bond, CM, 1998) |
| "Headache was frequent in the control (69%), i." | 2.68 | The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison. ( van den Berg, AA, 1996) |
| "The metoclopramide regimen was five times as expensive as prochlorperazine." | 2.67 | A randomised double-blind study of high-dose intravenous prochlorperazine versus high-dose metoclopramide as antiemetics for cancer chemotherapy. ( Bishop, JF; Buchanan, L; Cooper, IA; Laidlaw, C; Matthews, J; Olver, IN; Smith, R; Wolf, M, 1992) |
| "Nausea and emesis are significant side effects in patients undergoing stereotactic radiosurgery for brain lesions in the region of the chemoreceptor trigger zone (area postrema of the brain)." | 2.67 | The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone. ( Alexander, E; Bodis, S; Kooy, H; Loeffler, JS, 1994) |
| "Nabilone was significantly superior to prochlorperazine in the reduction of vomiting episodes." | 2.66 | A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. ( Mattson, K; Niiranen, A, 1985) |
| " Optimal dosage and pharmacokinetic distribution of both drugs should be investigated further." | 2.66 | Comparative effects of intravenously administered alizapride and prochlorperazine in cisplatin-induced emesis. ( Desjardins, R; Ellison, R; Hyman, G; Nahas, G; Roché, H; Stoopler, M, 1987) |
| "Metoclopramide was superior to placebo and to prochlorperazine in reducing the volume of emesis (P = 0." | 2.65 | Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting. ( Bordin, LA; Braun, DW; Braun, TJ; Gralla, RJ; Itri, LM; Kelsen, DP; Pisko, SE; Squillante, AE; Young, CW, 1981) |
| "Nausea was absent in 40 of 55 patients receiving THC, eight of 55 patients receiving prochlorperazine, and five of 55 in the placebo group." | 2.65 | Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. ( Bloome, B; McKernan, JF; Orr, LE, 1980) |
| "Nabilone is an effective oral anti-emetic drug for moderately toxic chemotherapy, but the range and unpredictability of its side-effects warrant caution in its use." | 2.65 | Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. ( Ahmedzai, S; Calder, IT; Carlyle, DL; Moran, F, 1983) |
| " With the dosage and schedule we used, and in our patient population of largely elderly adults, THC therapy resulted in an overall more unpleasant treatment experience than that noted with prochlorperazine or placebo." | 2.65 | Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo. ( Creagan, ET; Frytak, S; Moertel, CG; O'Connell, MJ; O'Fallon, JR; Rubin, J; Schutt, AJ; Schwartau, NW, 1979) |
| "Vomiting was significantly more frequent in the placebo-treated group [0." | 2.64 | A controlled trial of antiemetics in abortion by PGF2alpha and laminaria. ( Federschneider, JM; Kaul, AF; Stubblefield, PG, 1978) |
| "Nausea and vomiting is a common and distressing presenting complaint in emergency departments (ED)." | 2.52 | Drugs for the treatment of nausea and vomiting in adults in the emergency department setting. ( Egerton-Warburton, D; Furyk, JS; Meek, RA, 2015) |
| "Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines." | 2.41 | Anti-emetics. ( MacGregor, EA, 2001) |
| "Nausea and vomiting are common, but prevalence of antiemetic use in ED patients is unknown." | 1.43 | Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective. ( Garra, G; Singer, AJ; Thode, HC, 2016) |
| "Nausea was assessed on a 1-7 scale four times a day for 4 days by diary." | 1.36 | Insight in the prediction of chemotherapy-induced nausea. ( Colagiuri, B; Colman, L; Heckler, CE; Hoelzer, K; Jacobs, A; Morrow, GR; Pudlo, BD; Roscoe, JA, 2010) |
| " Thus, controlling the adverse side effects associated with radiation therapy is critical to optimal patient care." | 1.29 | Controlling the toxicity of palliative radiotherapy: the role of 5-HT3 antagonists. ( Priestman, TJ, 1996) |
| " No adverse effects were observed in our patients." | 1.28 | Pharmacokinetics and safety of prochlorperazine in paediatric patients receiving cancer chemotherapy. ( Ford, C; Nahata, MC; Ruymann, FB, 1992) |
| "Prochlorperazine in plasma was assayed by high performance liquid chromatography with electrochemical detection and pharmacokinetics were determined for three patients at the 1." | 1.28 | A dose finding study of prochlorperazine as an antiemetic for cancer chemotherapy. ( Bishop, JF; Clarke, J; Hillcoat, BL; Olver, IN; Webster, LK, 1989) |
| " If no response was observed within 20 minutes, the dosage was repeated." | 1.27 | Intravenous prochlorperazine for the rapid control of vomiting in the emergency department. ( Balasubramaniam, S; Herman, LS; Ordog, GJ; Owashi, ND; Vann, PW; Wasserberger, J, 1984) |
| "Vomiting was observed more frequently after non intra-ocular surgery than after intra-ocular surgery (37% cf." | 1.27 | Vomiting after ophthalmic surgery. Effects of intra-operative antiemetics and postoperative oral fluid restriction. ( Laghari, NA; Lambourne, A; Van den Berg, AA; Yazji, NS, 1987) |
| "Haloperidol has the shortest onset of action, being effective within 30 minutes of intravenous administration." | 1.26 | Comparison of droperidol, haloperidol and prochlorperazine as postoperative anti-emetics. ( Bennett, G; Loeser, EA; Machin, R; Stanley, TH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (57.62) | 18.7374 |
| 1990's | 33 (21.85) | 18.2507 |
| 2000's | 12 (7.95) | 29.6817 |
| 2010's | 16 (10.60) | 24.3611 |
| 2020's | 3 (1.99) | 2.80 |
| Authors | Studies |
|---|---|
| Javed, S | 1 |
| Hussain, A | 1 |
| Shah, PA | 1 |
| Raza, SA | 1 |
| Anwer, UU | 1 |
| Shamim, R | 1 |
| Rasool, F | 1 |
| Hafiz, MA | 1 |
| Bukhari, NI | 1 |
| Haldipur, D | 1 |
| Krishnamurthy, N | 1 |
| A, B | 1 |
| Kow, CS | 1 |
| Hasan, SS | 1 |
| Tsukuura, H | 2 |
| Miyazaki, M | 1 |
| Morita, T | 1 |
| Sugishita, M | 2 |
| Kato, H | 1 |
| Murasaki, Y | 1 |
| Gyawali, B | 2 |
| Kubo, Y | 1 |
| Ando, M | 1 |
| Kondo, M | 1 |
| Yamada, K | 1 |
| Hasegawa, Y | 2 |
| Ando, Y | 2 |
| Ouellette, L | 1 |
| Judge, B | 1 |
| Zamarripa, A | 1 |
| McFadden, P | 1 |
| Jones, J | 1 |
| Yomiya, K | 1 |
| Takei, D | 1 |
| Kurosawa, H | 1 |
| Kono, B | 1 |
| Furyk, JS | 2 |
| Meek, R | 2 |
| McKenzie, S | 1 |
| Yamada, T | 1 |
| Kanazawa, Y | 1 |
| Aoki, Y | 1 |
| Uchida, E | 1 |
| Meek, RA | 1 |
| Egerton-Warburton, D | 2 |
| Matsumoto, M | 1 |
| Honda, K | 1 |
| Urakawa, H | 1 |
| Maeda, O | 1 |
| Smith, LA | 1 |
| Azariah, F | 1 |
| Lavender, VT | 1 |
| Stoner, NS | 1 |
| Bettiol, S | 1 |
| Lau Moon Lin, M | 1 |
| Robinson, PD | 1 |
| Flank, J | 1 |
| Sung, L | 1 |
| Dupuis, LL | 1 |
| Waqar, SN | 1 |
| Mann, J | 1 |
| Baggstrom, MQ | 1 |
| Waqar, MA | 1 |
| Chitneni, P | 1 |
| Williams, K | 1 |
| Gao, F | 1 |
| Morgensztern, D | 1 |
| Govindan, R | 1 |
| Singer, AJ | 1 |
| Garra, G | 1 |
| Thode, HC | 1 |
| Roscoe, JA | 2 |
| Morrow, GR | 2 |
| Colagiuri, B | 1 |
| Heckler, CE | 1 |
| Pudlo, BD | 1 |
| Colman, L | 1 |
| Hoelzer, K | 1 |
| Jacobs, A | 1 |
| Patanwala, AE | 1 |
| Amini, R | 1 |
| Hays, DP | 1 |
| Rosen, P | 1 |
| Trepanier, L | 1 |
| Mee, MJ | 1 |
| Wickham, R | 1 |
| MacGregor, EA | 1 |
| GRAY, WD | 1 |
| BERMAN, HH | 1 |
| LAZAR, M | 1 |
| NOE, O | 1 |
| SULLIVAN, CL | 1 |
| PRICE, NJ | 1 |
| HOPKINS, CE | 1 |
| GEPPERT, TV | 1 |
| DAESCHNER, GL | 1 |
| MATTHES, FT | 1 |
| DAESCHNER, CW | 1 |
| CLEVELAND, WW | 1 |
| SMITH, GF | 1 |
| CAZZOLA, D | 1 |
| SACREZ, A | 1 |
| ASCH, L | 1 |
| DOUGAN, HT | 1 |
| BELLERO, V | 1 |
| FAGNANO, G | 1 |
| CRISTOFARI, U | 1 |
| NOCCA, G | 1 |
| CIPRIANI, G | 1 |
| FASSINA, GF | 1 |
| DIAMOND, EF | 1 |
| LIMPERIS, NM | 1 |
| BEZZI, G | 1 |
| SABA, G | 1 |
| CALA, G | 1 |
| PERNIOLA, V | 1 |
| DE MARCHI, A | 1 |
| GATTO, A | 1 |
| MOERTEL, CG | 4 |
| REITEMEIER, RJ | 2 |
| GAGE, RP | 1 |
| SYLVESTER, WR | 1 |
| MORTON, WR | 1 |
| TURNBULL, W | 1 |
| WEAVER, LC | 1 |
| RAHDERT, E | 1 |
| RICHARDS, AB | 1 |
| ABREU, BE | 1 |
| HOWAT, DD | 1 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| Lindley, C | 1 |
| Goodin, S | 1 |
| McCune, J | 1 |
| Kane, M | 1 |
| Amamoo, MA | 1 |
| Shord, S | 1 |
| Pham, T | 1 |
| Yowell, S | 1 |
| Laliberte, K | 1 |
| Schell, M | 1 |
| Bernard, S | 1 |
| Socinski, MA | 1 |
| Hickok, JT | 1 |
| Bole, CW | 1 |
| Zhao, H | 1 |
| Hoelzer, KL | 1 |
| Dakhil, SR | 1 |
| Moore, T | 1 |
| Fitch, TR | 1 |
| Vinson, DR | 2 |
| Niamatali, C | 1 |
| Fallon, SD | 1 |
| Egan, EL | 1 |
| Bakowski, MT | 1 |
| Fahmy, K | 1 |
| Kotlarek-Haus, S | 1 |
| Orzechowska-Juzwenko, K | 1 |
| Gabryś, K | 1 |
| Orr, LE | 1 |
| McKernan, JF | 1 |
| Bloome, B | 1 |
| Ungerleider, JT | 2 |
| Andrysiak, T | 1 |
| Fairbanks, L | 1 |
| Goodnight, J | 1 |
| Sarna, G | 1 |
| Jamison, K | 1 |
| Johansson, R | 1 |
| Kilkku, P | 1 |
| Groenroos, M | 1 |
| Einhorn, L | 1 |
| Ahmedzai, S | 1 |
| Carlyle, DL | 1 |
| Calder, IT | 2 |
| Moran, F | 1 |
| Andrysiak, TA | 1 |
| Fairbanks, LA | 1 |
| Tesler, AS | 1 |
| Parker, RG | 1 |
| Sheidler, VR | 1 |
| Ettinger, DS | 2 |
| Diasio, RB | 1 |
| Enterline, JP | 1 |
| Brown, MD | 1 |
| Bishop, JF | 7 |
| Olver, IN | 5 |
| Wolf, MM | 2 |
| Matthews, JP | 5 |
| Long, M | 1 |
| Bingham, J | 1 |
| Hillcoat, BL | 3 |
| Cooper, IA | 3 |
| Markman, M | 1 |
| Sheidler, V | 1 |
| Quaskey, SA | 1 |
| Mellits, ED | 1 |
| Chacón, RD | 1 |
| Bruera, ED | 1 |
| Roca, E | 1 |
| Chan, SC | 1 |
| Lo, JR | 1 |
| Wong, KC | 1 |
| Ordog, GJ | 2 |
| Vann, PW | 1 |
| Owashi, ND | 1 |
| Wasserberger, J | 2 |
| Herman, LS | 2 |
| Balasubramaniam, S | 1 |
| Winokur, SH | 1 |
| Baker, JJ | 1 |
| Lokey, JL | 1 |
| Price, NA | 1 |
| Bowen, J | 1 |
| Neidhart, JA | 1 |
| Gagen, M | 1 |
| Young, D | 1 |
| Wilson, HE | 1 |
| Gralla, RJ | 1 |
| Itri, LM | 1 |
| Pisko, SE | 1 |
| Squillante, AE | 1 |
| Kelsen, DP | 1 |
| Braun, DW | 1 |
| Bordin, LA | 1 |
| Braun, TJ | 1 |
| Young, CW | 1 |
| Jacobs, AJ | 1 |
| Deppe, G | 2 |
| Cohen, CJ | 1 |
| Scarantino, CW | 1 |
| Ornitz, RD | 1 |
| Hoffman, LG | 1 |
| Anderson, RF | 1 |
| Hesketh, P | 1 |
| Allen, DL | 1 |
| Kitching, AJ | 1 |
| Nagle, C | 1 |
| van den Berg, AA | 6 |
| Bodis, S | 1 |
| Alexander, E | 1 |
| Kooy, H | 1 |
| Loeffler, JS | 1 |
| Smith, RA | 1 |
| Laidlaw, CR | 1 |
| Hayes, AM | 1 |
| Wolf, M | 3 |
| Toner, GC | 1 |
| Fanning, J | 1 |
| Hilgers, RD | 1 |
| Barrow, PM | 1 |
| Hughes, DG | 1 |
| Redfern, N | 1 |
| Urie, J | 1 |
| Fleishman, SB | 1 |
| Lavin, MR | 1 |
| Sattler, M | 1 |
| Szarka, H | 1 |
| Suen, TK | 1 |
| Gin, TA | 1 |
| Chen, PP | 1 |
| Rowbottom, YM | 1 |
| Critchley, LA | 1 |
| Ray, AK | 1 |
| Priestman, TJ | 2 |
| Roberts, JT | 1 |
| Upadhyaya, BK | 1 |
| Matsui, K | 1 |
| Fukuoka, M | 1 |
| Takada, M | 1 |
| Kusunoki, Y | 1 |
| Yana, T | 1 |
| Tamura, K | 1 |
| Yoshida, T | 1 |
| Iida, K | 1 |
| Hirashima, T | 1 |
| Tsukada, H | 1 |
| Ushijima, S | 1 |
| Miyawaki, H | 1 |
| Masuda, N | 1 |
| Gilbert, CJ | 1 |
| Ohly, KV | 1 |
| Rosner, G | 1 |
| Peters, WP | 1 |
| Alberts, VA | 1 |
| Catalano, G | 1 |
| Poole, MA | 1 |
| Bond, CM | 1 |
| Devlin, J | 1 |
| Wagstaff, K | 1 |
| Arthur, V | 1 |
| Emery, P | 1 |
| Kwong, WJ | 1 |
| Parasuraman, TV | 1 |
| Hesketh, PJ | 1 |
| Roman, A | 1 |
| Hesketh, AM | 1 |
| Perez, EA | 1 |
| Edelman, M | 1 |
| Gandara, DR | 1 |
| Ernst, AA | 1 |
| Weiss, SJ | 1 |
| Park, S | 1 |
| Takakuwa, KM | 1 |
| Diercks, DB | 1 |
| van Gijn, J | 1 |
| Drotts, DL | 1 |
| Morgan, RJ | 1 |
| Synold, T | 1 |
| Carr, BI | 2 |
| Doroshow, JH | 1 |
| Womack, EP | 1 |
| Shibata, S | 1 |
| Somlo, G | 1 |
| Raschko, J | 1 |
| Leong, L | 1 |
| McNamara, M | 1 |
| Chow, W | 1 |
| Tetef, M | 1 |
| Margolin, K | 1 |
| Akman, S | 1 |
| Longmate, J | 1 |
| Collins, RW | 1 |
| Jones, JB | 1 |
| Walthall, JD | 1 |
| Chisholm, CD | 1 |
| Giles, BK | 1 |
| Brizendine, EJ | 1 |
| Cordell, WH | 1 |
| Kaul, AF | 1 |
| Federschneider, JM | 1 |
| Stubblefield, PG | 1 |
| Ekert, H | 1 |
| Waters, KD | 1 |
| Jurk, IH | 1 |
| Mobilia, J | 1 |
| Loughnan, P | 1 |
| Herman, TS | 1 |
| Einhorn, LH | 1 |
| Jones, SE | 1 |
| Nagy, C | 1 |
| Chester, AB | 1 |
| Dean, JC | 1 |
| Furnas, B | 1 |
| Williams, SD | 1 |
| Leigh, SA | 1 |
| Dorr, RT | 1 |
| Moon, TE | 1 |
| Klener, P | 1 |
| Loeser, EA | 1 |
| Bennett, G | 1 |
| Stanley, TH | 1 |
| Machin, R | 1 |
| Frytak, S | 1 |
| O'Fallon, JR | 2 |
| Rubin, J | 1 |
| Creagan, ET | 1 |
| O'Connell, MJ | 1 |
| Schutt, AJ | 2 |
| Schwartau, NW | 1 |
| Robins, HI | 1 |
| Ershler, WB | 1 |
| De Jongh, L | 1 |
| Chang, YC | 1 |
| Drozdowicz, PM | 1 |
| Meyer, DK | 1 |
| Borison, HL | 1 |
| McCarthy, LE | 1 |
| London, SW | 1 |
| Gruber, W | 1 |
| Brenner, WE | 4 |
| Staurovsky, LG | 3 |
| Dingfelder, JR | 1 |
| Wells, JS | 1 |
| Hahn, RG | 1 |
| Dingfelder, R | 1 |
| Laidlaw, C | 1 |
| Matthews, J | 1 |
| Smith, R | 1 |
| Buchanan, L | 2 |
| Oliver, IN | 1 |
| Reynolds, S | 1 |
| Walpole, E | 1 |
| Rischin, D | 1 |
| Tan, LG | 1 |
| Nahata, MC | 1 |
| Ford, C | 1 |
| Ruymann, FB | 1 |
| Lane, M | 2 |
| Vogel, CL | 1 |
| Ferguson, J | 1 |
| Krasnow, S | 1 |
| Saiers, JL | 1 |
| Hamm, J | 1 |
| Salva, K | 1 |
| Wiernik, PH | 1 |
| Holroyde, CP | 1 |
| Hammill, S | 1 |
| Warr, D | 1 |
| Willan, A | 1 |
| Fine, S | 1 |
| Wilson, K | 1 |
| Davis, A | 1 |
| Erlichman, C | 1 |
| Rusthoven, J | 1 |
| Lofters, W | 1 |
| Osoba, D | 1 |
| Laberge, F | 1 |
| Chambers, EJ | 1 |
| Louvet, C | 1 |
| Lorange, A | 1 |
| Letendre, F | 1 |
| Beaulieu, R | 1 |
| Pretty, HM | 1 |
| Courchesne, Y | 1 |
| Neemeh, JA | 1 |
| Monte, M | 1 |
| Latreille, J | 1 |
| Akhtar, SS | 1 |
| Bano, ZA | 1 |
| Bhat, GM | 1 |
| Bhat, MA | 1 |
| Ho, RT | 1 |
| Jawan, B | 1 |
| Fung, ST | 1 |
| Cheung, HK | 1 |
| Lee, JH | 1 |
| Smith, FE | 1 |
| Sullivan, RA | 1 |
| Plasse, TF | 1 |
| Malone, JM | 1 |
| Christensen, CW | 1 |
| Yashinsky, D | 1 |
| Malviya, VK | 1 |
| Webster, LK | 1 |
| Clarke, J | 1 |
| Mishra, VN | 1 |
| Singh, D | 1 |
| Wheelock, JB | 1 |
| Goldstein, D | 1 |
| Levi, JA | 1 |
| Woods, RL | 1 |
| Russell, J | 1 |
| Morgan, J | 1 |
| Kerestes, Z | 1 |
| Cramb, R | 1 |
| Fargas-Babjak, A | 1 |
| Hirano, G | 1 |
| Cunningham, D | 2 |
| Bradley, CJ | 1 |
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| Hutcheon, AW | 1 |
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| Soukop, M | 2 |
| Kaye, SB | 1 |
| Pullar, T | 1 |
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| Gilchrist, NL | 1 |
| McArdle, CS | 1 |
| Niiranen, A | 1 |
| Mattson, K | 1 |
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| Ota, K | 1 |
| Chan, HS | 1 |
| Correia, JA | 1 |
| MacLeod, SM | 1 |
| Silvey, L | 1 |
| Carpenter, JT | 1 |
| Wheeler, RH | 1 |
| Lee, J | 1 |
| Conolley, C | 1 |
| Ward, AE | 1 |
| Nino, S | 1 |
| Umehara, H | 1 |
| Inoue, I | 1 |
| Tamura, T | 1 |
| Sasaki, Y | 1 |
| Sakurai, M | 1 |
| Shinkai, T | 1 |
| Eguchi, K | 1 |
| Saijo, N | 1 |
| Suemasu, K | 1 |
| Scott, K | 1 |
| Ackland, S | 1 |
| Yuen, K | 1 |
| Morton, C | 1 |
| Triplett, WC | 1 |
| Schroeder, JE | 1 |
| Minnick, DJ | 1 |
| Dugan, WM | 1 |
| Berry, JA | 1 |
| Lau, JC | 1 |
| Gilston, M | 1 |
| Lambourne, A | 2 |
| Yazji, NS | 1 |
| Laghari, NA | 1 |
| Roché, H | 1 |
| Hyman, G | 1 |
| Nahas, G | 1 |
| Stoopler, M | 1 |
| Ellison, R | 1 |
| Desjardins, R | 1 |
| Klein, DS | 1 |
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| Mahaley, MS | 1 |
| Cersosimo, RJ | 1 |
| Bromer, R | 1 |
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| Abrahamson, M | 1 |
| Hong, WK | 1 |
| Aasebø, U | 1 |
| Myhr, K | 1 |
| Luesley, DM | 1 |
| Terry, PB | 1 |
| Chan, KK | 1 |
| Berk, BZ | 1 |
| Hendricks, CH | 2 |
| Braaksma, JT | 2 |
| Fishburne, JI | 2 |
| Kroncke, FG | 1 |
| Staurovsky, L | 1 |
| Berry, GH | 1 |
| Duncan, W | 1 |
| Bowman, CM | 1 |
| Bardfeld, PA | 1 |
| Anderson, OW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department[NCT04464915] | 0 participants (Actual) | Interventional | 2020-07-31 | Withdrawn (stopped due to Given the COVID-19 pandemic, there has been a temporary suspension of study activities, therefore the study has not yet been initiated.) | |||
| Effect of Ketamine Versus Sevoflurane On The Right Ventricular Pressure During Congenital Pulmonary Stenosis Balloon Dilatation[NCT05582213] | 40 participants (Actual) | Interventional | 2022-10-01 | Completed | |||
| Value of Ondansetron Medication vs Inhaled Isopropyl Therapy in the Emergency Department (VOMIITED)[NCT03125811] | Early Phase 1 | 121 participants (Actual) | Interventional | 2017-07-17 | Completed | ||
| Randomized Single-Blind Study of Nometex as an Adjunct to Standard Anti-emetics in Ovarian and Advanced Endometrial and Cervical Cancer Patients Who Receive Moderately to Highly Emetogenic Chemotherapy[NCT01980160] | 0 participants (Actual) | Interventional | 2013-11-30 | Withdrawn (stopped due to Did not receive IRB approval from our institution therefore the study was closed.) | |||
| Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.[NCT03606369] | Phase 2/Phase 3 | 560 participants (Anticipated) | Interventional | 2015-11-05 | Recruiting | ||
| Treatment of Delayed Nausea: What Works Best?[NCT00020657] | Phase 3 | 0 participants | Interventional | 2001-07-31 | Completed | ||
| A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872] | Phase 4 | 500 participants (Actual) | Interventional | 2017-09-05 | Terminated (stopped due to no longer recruiting or studying) | ||
| A Phase III Randomized, Double-blind, Placebo-controlled, Cross-over Study to Evaluate Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer Receiving 5-day Cisplatin C[NCT05244577] | Phase 3 | 75 participants (Anticipated) | Interventional | 2022-01-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for prochlorperazine and Vomiting
| Article | Year |
|---|---|
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; N | 2015 |
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup | 2015 |
The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis.
Topics: Antiemetics; Antineoplastic Agents; Chemotherapy-Induced Febrile Neutropenia; Child; Child Health Se | 2016 |
Antiemetic therapy for nausea and vomiting in the emergency department.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P | 2010 |
Antiemetic therapy for nausea and vomiting in the emergency department.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P | 2010 |
Antiemetic therapy for nausea and vomiting in the emergency department.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P | 2010 |
Antiemetic therapy for nausea and vomiting in the emergency department.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; P | 2010 |
Acute vomiting in cats: rational treatment selection.
Topics: Acute Disease; Animals; Antiemetics; Cat Diseases; Cats; Chlorpromazine; Diarrhea; Famotidine; Indol | 2010 |
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting.
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2012 |
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting.
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2012 |
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting.
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2012 |
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting.
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2012 |
Anti-emetics.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Humans; Metoclopramide; Migraine Disorders; Nausea; | 2001 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do | 1984 |
Prophylaxis with oral granisetron for acute emesis induced by moderately emetogenic chemotherapy.
Topics: Acute Disease; Administration, Oral; Antiemetics; Antineoplastic Agents; Drug Administration Schedul | 1995 |
Radiotherapy in paediatric practice.
Topics: Child; Humans; Neoplasms; Palliative Care; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prochlorp | 1991 |
[Recent advances in the management of chemotherapy-induced emesis].
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy, | 1986 |
70 trials available for prochlorperazine and Vomiting
| Article | Year |
|---|---|
Efficacy of Prophylactic Treatment for Oxycodone-Induced Nausea and Vomiting Among Patients with Cancer Pain (POINT): A Randomized, Placebo-Controlled, Double-Blind Trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Cancer Pain; Double-Blind Method; F | 2018 |
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast | 2005 |
5-Hydroxytryptamine-receptor antagonists versus prochlorperazine for control of delayed nausea caused by doxorubicin: a URCC CCOP randomised controlled trial.
Topics: Antiemetics; Antineoplastic Agents; Dexamethasone; Doxorubicin; Female; Humans; Male; Middle Aged; N | 2005 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Do | 1984 |
Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis.
Topics: Adult; Aged; Antineoplastic Agents; Double-Blind Method; Dronabinol; Female; Humans; Male; Middle Ag | 1980 |
Cannabis and cancer chemotherapy: a comparison of oral delta-9-THC and prochlorperazine.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Antineoplastic Agents; Clinical Trials a | 1982 |
A double-blind, controlled trial of nabilone vs. prochlorperazine for refractory emesis induced by cancer chemotherapy.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind | 1982 |
Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cli | 1983 |
Tetrahydrocannabinol vs. prochlorperazine. The effects of two antiemetics on patients undergoing radiotherapy.
Topics: Adolescent; Adult; Antiemetics; Clinical Trials as Topic; Double-Blind Method; Dronabinol; Emotions; | 1984 |
Double-blind multiple-dose crossover study of the antiemetic effect of intramuscular levonantradol compared to prochlorperazine.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind | 1984 |
Lorazepam: a randomized, double-blind, crossover study of a new antiemetic in patients receiving cytotoxic chemotherapy and prochlorperazine.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials | 1984 |
Antiemetic efficacy of dexamethasone. Randomized, double-blind, crossover study with prochlorperazine in patients receiving cancer chemotherapy.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Dexamethasone; Double-Bli | 1984 |
Vomiting after anaesthesia for termination of pregnancy in Chinese.
Topics: Abortion, Induced; Anesthesia, Obstetrical; China; Ethnicity; Female; Humans; Metoclopramide; Preane | 1983 |
Dexamethasone in the treatment of nausea and vomiting from cancer chemotherapy.
Topics: Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Dr | 1981 |
Specific antiemetics for specific cancer chemotherapeutic agents: haloperidol versus benzquinamide.
Topics: Adult; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Doxorubicin; | 1981 |
Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting.
Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoclo | 1981 |
A comparison of the antiemetic effects of droperidol and prochlorperazine in chemotheray with cis-platinum.
Topics: Antiemetics; Cisplatin; Droperidol; Female; Genital Neoplasms, Female; Humans; Prochlorperazine; Vom | 1980 |
On the mechanism of radiation-induced emesis: the role of serotonin.
Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic | 1994 |
P6 acupressure and nausea and vomiting after gynaecological surgery.
Topics: Acupuncture Points; Acupuncture Therapy; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Fem | 1994 |
The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone.
Topics: Adult; Aged; Cerebral Ventricles; Female; Humans; Male; Middle Aged; Nausea; Ondansetron; Pilot Proj | 1994 |
The roles of patient and observer assessments in anti-emetic trials.
Topics: Cross-Over Studies; Double-Blind Method; Humans; Lorazepam; Metoclopramide; Nurses; Observer Variati | 1994 |
A randomised double blind crossover study of domperidone and prochlorperazine suppositories for controlling emesis in outpatients receiving chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Diarrhea; Domperidone; Double-Blind Method; Female; Humans; Male | 1994 |
Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Dexamethasone; Diphenh | 1994 |
Influence of droperidol on nausea and vomiting during patient-controlled analgesia.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Droperidol; Female; Humans; Middle Aged; Morphine; Nause | 1994 |
Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery.
Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Double-Blind Method; Female; Follow-Up Studi | 1994 |
A prospective randomized double-blind trial comparing ondansetron versus prochlorperazine for the prevention of nausea and vomiting in patients undergoing fractionated radiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Middle Aged; Nausea; Neop | 1993 |
Randomised trial for the prevention of delayed emesis in patients receiving high-dose cisplatin.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Agents; Carcinom | 1996 |
Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation.
Topics: Adult; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combine | 1995 |
Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy.
Topics: Adenoidectomy; Adolescent; Adult; Aged; Antiemetics; Child; Child, Preschool; Double-Blind Method; F | 1996 |
A comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after tympanoplasty.
Topics: Adolescent; Adult; Antiemetics; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Nause | 1996 |
The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison.
Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Blood Pressure; Child; Double-Blind Method; Fem | 1996 |
Comparison of buccal and oral prochlorperazine in the treatment of dizziness associated with nausea and/or vomiting.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antiemetics; Cheek; Dizziness; Double-Blind Method; F | 1998 |
Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil).
Topics: Antiemetics; Arthritis; Granisetron; Humans; Methotrexate; Nausea; Prochlorperazine; Single-Blind Me | 1999 |
Control of high-dose-cisplatin-induced emesis with an all-oral three-drug antiemetic regimen.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Cisplatin; | 2000 |
Prochlorperazine versus promethazine for uncomplicated nausea and vomiting in the emergency department: a randomized, double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antiemetics; Double-Blind Method; Emergency Service, | 2000 |
Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antiemetics; Conscious Sedation; Diphenhydramine; Double | 2001 |
Continuous infusion prochlorperazine: pharmacokinetics, antiemetic efficacy, and feasibility of high-dose therapy.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Cisplatin; Female; Humans; Infus | 2001 |
Intravenous administration of prochlorperazine by 15-minute infusion versus 2-minute bolus does not affect the incidence of akathisia: a prospective, randomized, controlled trial.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Dose-Response Relationship, Drug; Double-Blind Met | 2001 |
A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.
Topics: Abortion, Induced; Adolescent; Adult; Amnion; Analgesics, Opioid; Antiemetics; Clinical Trials as To | 1978 |
Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.
Topics: Antiemetics; Antineoplastic Agents; Child; Clinical Trials as Topic; Double-Blind Method; Dronabinol | 1979 |
Superiority of nabilone over prochlorperazine as an antiemetic in patients receiving cancer chemotherapy.
Topics: Adolescent; Adult; Aged; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Dronabinol; D | 1979 |
Delta-9-tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A comparison with prochlorperazine and a placebo.
Topics: Adult; Aged; Antiemetics; Double-Blind Method; Dronabinol; Drug Evaluation; Fluorouracil; Gastrointe | 1979 |
Oral benzquinamide in the treatment of nausea and vomiting.
Topics: Clinical Trials as Topic; Fluorouracil; Humans; Nausea; Prochlorperazine; Quinolizines; Vomiting | 1975 |
A randomised double-blind study of high-dose intravenous prochlorperazine versus high-dose metoclopramide as antiemetics for cancer chemotherapy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Cisplatin; Female; H | 1992 |
A randomised trial of dexamethasone, lorazepam and prochlorperazine for emesis in patients receiving chemotherapy.
Topics: Adult; Aged; Antiemetics; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; | 1992 |
Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting.
Topics: Adult; Aged; Antineoplastic Agents; Double-Blind Method; Dronabinol; Drug Therapy, Combination; Fema | 1991 |
Superiority of granisetron to dexamethasone plus prochlorperazine in the prevention of chemotherapy-induced emesis.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Double-Blind Method; Dru | 1991 |
A double-blind randomized cross-over comparison of high-dose prochlorperazine with high-dose metoclopramide for cisplatin-induced emesis.
Topics: Adult; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Mal | 1991 |
Electro-acupuncture and postoperative emesis.
Topics: Adolescent; Adult; Anesthesia, General; Electroacupuncture; Female; Humans; Laparoscopy; Middle Aged | 1990 |
Dronabinol and prochlorperazine alone and in combination as antiemetic agents for cancer chemotherapy.
Topics: Adult; Antineoplastic Agents; Double-Blind Method; Dronabinol; Drug Administration Schedule; Drug Th | 1990 |
Prochlorperazine and transdermal scopolamine added to a metoclopramide antiemetic regimen. A controlled comparison.
Topics: Administration, Cutaneous; Cisplatin; Female; Genital Neoplasms, Female; Humans; Infusions, Intraven | 1990 |
Pentobarbital's effect in a combination antiemetic regimen for cisplatin induced nausea and vomiting.
Topics: Cisplatin; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; | 1989 |
Double-blind randomized cross-over trial of dexamethasone and prochlorperazine as anti-emetics for cancer chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Dexamethasone; Double-Blind Method; Fe | 1989 |
Intraoperative prochlorperazine for prevention of post-operative nausea and vomiting.
Topics: Adult; Anesthesia, Intravenous; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Inj | 1989 |
A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.
Topics: Adolescent; Adult; Aged; Antiemetics; Cisplatin; Clinical Trials as Topic; Dexamethasone; Dronabinol | 1988 |
Sulphasalazine in the treatment of rheumatoid arthritis: relationship of dose and serum levels to efficacy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Dose-Response Rel | 1985 |
Nabilone and prochlorperazine: a useful combination for emesis induced by cytotoxic drugs.
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Dron | 1985 |
A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy.
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Appetite; Blood Pressure | 1985 |
Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; D | 1987 |
A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclopho | 1988 |
Studies of prochlorperazine as a buccal tablet (Buccastem) and an oral tablet (Stemetil) for the treatment of dizziness, nausea or vomiting in a general practice setting.
Topics: Administration, Buccal; Administration, Oral; Adult; Aged; Clinical Trials as Topic; Dizziness; Doub | 1988 |
[A randomized controlled trial of acute and delayed cisplatin-induced emesis with metoclopramide, dexamethasone and prochlorperazine].
Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Dexamethasone; Drug Therapy, Combination; Female; | 1987 |
Randomized, double-blind, cross-over study comparing prochlorperazine and lorazepam with high-dose metoclopramide and lorazepam for the control of emesis in patients receiving cytotoxic chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Com | 1987 |
Reliability of videotape technology in assessing the efficacy of anti-emetic drugs.
Topics: Antiemetics; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Droperidol; Humans; Prochlorp | 1986 |
Intravenous prochlorperazine for the rapid control of nausea and vomiting in acute myocardial infarction: a clinical observation.
Topics: Aged; Clinical Trials as Topic; Emergencies; Female; Humans; Injections, Intravenous; Male; Myocardi | 1987 |
Comparative effects of intravenously administered alizapride and prochlorperazine in cisplatin-induced emesis.
Topics: Adult; Aged; Cisplatin; Female; Humans; Injections, Intravenous; Male; Middle Aged; Prochlorperazine | 1987 |
Controlled studies of metopimazine for the treatment of nausea and vomiting.
Topics: Antiemetics; Clinical Trials as Topic; Fluorouracil; Humans; Isonipecotic Acids; Nausea; Neoplasms; | 1973 |
The prevention of radiation sickness. Report of a double blind random clinical trial using prochlorperazine and metopimazine.
Topics: Clinical Trials as Topic; Humans; Nausea; Phenothiazines; Prochlorperazine; Radiation Injuries; Radi | 1971 |
A controlled double-blind study of trimethobenzamide, prochlorperazine, and placebo.
Topics: Adolescent; Adult; Aged; Benzamides; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Na | 1966 |
71 other studies available for prochlorperazine and Vomiting
| Article | Year |
|---|---|
Development of Optimized Sumatriptan-Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization.
Topics: Excipients; Humans; Migraine Disorders; Nausea; Prochlorperazine; Sumatriptan; Vomiting | 2022 |
The Real-World Safety and Effectiveness of Prochlorperazine in Indian Patients with Dizziness.
Topics: Antiemetics; Dizziness; Female; Humans; India; Male; Prochlorperazine; Prospective Studies; Vomiting | 2020 |
Prochlorperazine for nausea and vomiting accompanied COVID-19.
Topics: Antiemetics; COVID-19; Humans; Nausea; Prochlorperazine; Vomiting | 2021 |
Safety and effectiveness of intravenous prochlorperazine for intractable vomiting in children with gastroenteritis.
Topics: Administration, Intravenous; Antiemetics; Child; Gastroenteritis; Humans; Patient Safety; Prochlorpe | 2019 |
[A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction].
Topics: Antiemetics; Basal Ganglia Diseases; Female; Humans; Isoindoles; Male; Middle Aged; Nausea; Neoplasm | 2013 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra | 2014 |
Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Female; Humans; Incidence; Japan; M | 2015 |
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys; | 2015 |
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Lora | 2016 |
Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective.
Topics: Adult; Antiemetics; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Metocloprami | 2016 |
Insight in the prediction of chemotherapy-induced nausea.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast | 2010 |
Treatment and assessment of emergency department nausea and vomiting in Australasia: a survey of anti-emetic management.
Topics: Antiemetics; Australia; Clinical Protocols; Cross-Sectional Studies; Dopamine Antagonists; Emergency | 2011 |
An appraisal of a new antiemetic drug: prochlorperazine.
Topics: Antiemetics; Humans; Nausea; Phenothiazines; Prochlorperazine; Vomiting | 1957 |
Prochlorperazine as an antiemetic in the severely retarded child.
Topics: Antiemetics; Child; Humans; Infant; Intellectual Disability; Phenothiazines; Prochlorperazine; Vomit | 1958 |
Prochlorperazine for the treatment of nausea and vomiting of early pregnancy.
Topics: Female; Humans; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Prochlorperazine; Vomiti | 1958 |
The treatment of nausea and vomiting of pregnancy with prochlorperazine.
Topics: Female; Humans; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Prochlorperazine; Vomiti | 1958 |
Vomiting in infancy and early childhood; treatment with prochlorperazine.
Topics: Child; Child, Preschool; Humans; Infant; Phenothiazines; Prochlorperazine; Vomiting | 1958 |
Treatment of nausea and vomiting in children with prochlorperazine.
Topics: Child; Humans; Nausea; Phenothiazines; Prochlorperazine; Vomiting | 1958 |
Complications following the use of prochlorperazine (compazine) as an antiemetic.
Topics: Antiemetics; Child; Humans; Infant; Phenothiazines; Pigmentation; Prochlorperazine; Vomiting | 1958 |
[Use of prochlorperazine in obstetrics and gynecology].
Topics: Female; Genital Diseases, Female; Gynecology; Humans; Obstetrics; Phenothiazines; Pregnancy; Pregnan | 1959 |
[Neurological complications due to prochlorperazine].
Topics: Humans; Nervous System Diseases; Phenothiazines; Prochlorperazine; Vomiting | 1959 |
Prochlorperazine.
Topics: Child; Humans; Infant; Nausea; Phenothiazines; Prochlorperazine; Vomiting | 1959 |
[Prochlorperazine in therapy of nausea and vomiting in patients of heart disease after digitalis therapy].
Topics: Barbiturates; Digitalis; Heart Diseases; Humans; Nausea; Prochlorperazine; Vomiting | 1959 |
[Use of prochlorperazine as adjuvant in therapy of secondary phenomena in cancer patients].
Topics: Humans; Neoplasms; Phenothiazines; Prochlorperazine; Spasm; Vomiting | 1959 |
[A new tranquilizing and anti-emetic drug of the phenothiazine group: prochlorperazine].
Topics: Antiemetics; Emotions; Humans; Phenothiazines; Prochlorperazine; Tranquilizing Agents; Vomiting | 1959 |
[Postanesthetic vomiting. It's treatment with a new derivative of phenothiazine: prochlorpemazine].
Topics: Phenothiazines; Prochlorperazine; Surgical Procedures, Operative; Vomiting | 1960 |
[Evaluation of injectable prochlorperazine in the treatment of postoperative vomitting].
Topics: Humans; Postoperative Care; Postoperative Period; Prochlorperazine; Vomiting | 1961 |
Motility disturbances caused by prochlorperazine.
Topics: Cell Movement; Child; Humans; Infant; Prochlorperazine; Seizures; Vomiting | 1961 |
[Action of prochlorperazine on post-anesthetic vomiting].
Topics: Anesthesia; Anesthetics; Iatrogenic Disease; Prochlorperazine; Vomiting | 1960 |
[The use of prochlorpemazine in the prevention of postoperative vomiting].
Topics: Anesthesia; Anesthesia, General; Anesthesiology; Biomedical Research; Humans; Postoperative Nausea a | 1960 |
[Prochlorperazine in obstetrics and gynecology].
Topics: Female; Genitalia; Genitalia, Female; Gynecology; Humans; Neoplasms; Obstetrics; Pregnancy; Pregnanc | 1959 |
A CONTROLLED CLINICAL EVALUATION OF ANTIEMETIC DRUGS.
Topics: Antiemetics; Benzamides; Fluorouracil; Humans; Pharmacology; Prochlorperazine; Tranquilizing Agents; | 1963 |
NAUSEA AND VOMITING IN PREGNANCY.
Topics: Female; Humans; Hydroxyzine; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Toxicolog | 1964 |
PROMAZINE AND MEPERIDINE (SPARIDOL 50), AN EFFICIENT COMBINATION FOR PREOPERATIVE MEDICATION.
Topics: Analgesics, Opioid; Antipsychotic Agents; Eye; Geriatrics; Humans; Meperidine; Nausea; Pentobarbital | 1964 |
EFFECT OF ANTIEMETICS AND OTHER COMPOUNDS ON PROTOVERATRINE INDUCED EMESIS IN DOGS.
Topics: Antiemetics; Atropine; Benzamides; Dogs; Haloperidol; Meclizine; Niacin; Perphenazine; Pharmacology; | 1964 |
Anti-emetic drugs in anaesthesia. A double blind trial of two phenothiazine derivatives.
Topics: Anesthesia; Anesthesiology; Antiemetics; Double-Blind Method; Humans; Phenothiazines; Prochlorperazi | 1960 |
Development of a simplified instrument for the diagnosis and grading of akathisia in a cohort of patients receiving prochlorperazine.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Dopamine Antagonists; Female; Headach | 2006 |
Nabilone in the management of prochlorperazine resistant cancer chemotherapy induced emesis.
Topics: Antineoplastic Agents; Dronabinol; Humans; Nausea; Prochlorperazine; Vomiting | 1984 |
Prophylaxis against prostaglandin-induced gastrointestinal side effects.
Topics: Abortion, Induced; Antiemetics; Atropine; Diarrhea; Dinoprost; Diphenoxylate; Drug Combinations; Fem | 1981 |
[Vomiting accompanying cytostatic treatment, and its control].
Topics: Antiemetics; Antineoplastic Agents; Dronabinol; Drug Evaluation; Histamine H1 Antagonists; Humans; M | 1984 |
Marihuana for nausea and vomiting due to cancer chemotherapy.
Topics: Dronabinol; Drug-Related Side Effects and Adverse Reactions; Humans; Nausea; Neoplasms; Prochlorpera | 1980 |
Nabilone: an effective antiemetic agent in patients receiving cancer chemotherapy.
Topics: Antiemetics; Antineoplastic Agents; Blood Pressure; Dronabinol; Humans; Nausea; Prochlorperazine; Vo | 1982 |
[Emesis due to cytostatic drugs. Update and review of our experiences].
Topics: Antineoplastic Agents; Dexamethasone; Haloperidol; Humans; Metoclopramide; Prochlorperazine; Vomitin | 1983 |
Intravenous prochlorperazine for the rapid control of vomiting in the emergency department.
Topics: Adolescent; Adult; Aged; Emergency Medical Services; Female; Humans; Infusions, Parenteral; Injectio | 1984 |
Which routine antiemetic: ondansetron or prochlorperazine?
Topics: Humans; Ondansetron; Postoperative Complications; Prochlorperazine; Vomiting | 1994 |
Antiemetic-induced akathisia in cancer patients receiving chemotherapy.
Topics: Akathisia, Drug-Induced; Antineoplastic Agents; Drug Therapy, Combination; Female; Humans; Male; Met | 1994 |
Controlling the toxicity of palliative radiotherapy: the role of 5-HT3 antagonists.
Topics: Antiemetics; Clinical Trials as Topic; Dopamine Antagonists; Humans; Metoclopramide; Nausea; Neoplas | 1996 |
Tardive dyskinesia as a result of long-term prochlorperazine use.
Topics: Antiemetics; Dopamine Antagonists; Dyskinesia, Drug-Induced; Fatal Outcome; Female; Granisetron; Hum | 1996 |
Cost-effectiveness analysis of oral ondansetron and prochlorperazine for preventing nausea and vomiting after moderately emetogenic chemotherapy.
Topics: Administration, Oral; Antiemetics; Antineoplastic Agents; Clinical Trials as Topic; Cost-Benefit Ana | 1999 |
Case problem: presenting conventional and complementary approaches for relieving nausea in a breast cancer patient undergoing chemotherapy.
Topics: Acupressure; Acupuncture Therapy; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols | 2000 |
[Diagnostic image (17). Acute dystonia induced by prochlorperazine].
Topics: Acute Disease; Antiemetics; Child; Dyskinesia, Drug-Induced; Female; Humans; Muscle Relaxants, Centr | 2000 |
[Prochlorperazine Spofa in the therapy and prevention of nausea and vomiting following cytostatics].
Topics: Antineoplastic Agents; Humans; Nausea; Prochlorperazine; Vomiting | 1979 |
Comparison of droperidol, haloperidol and prochlorperazine as postoperative anti-emetics.
Topics: Droperidol; Haloperidol; Humans; Postoperative Complications; Prochlorperazine; Sodium Chloride; Vom | 1979 |
Antiemetic effect of intravenous diazepam in patients receiving cis-diamminedichloroplatinum II: a pilot study.
Topics: Adolescent; Adult; Aged; Cisplatin; Diazepam; Drug Therapy, Combination; Female; Humans; Male; Pilot | 1979 |
Cannabinoids and emesis.
Topics: Animals; Antiemetics; Antineoplastic Agents; Cats; Dronabinol; Prochlorperazine; Vomiting | 1978 |
Evaluation of intramuscular 15(s)-15-methyl prostaglandin F2 alpha tromethamine salt for induction of abortion, medications to attenuate side effects, and intracervical laminaria tents.
Topics: Abortion, Induced; Adolescent; Adult; Blood Pressure; Body Temperature; Cervix Uteri; Diarrhea; Diph | 1976 |
The efficacy and safety of intramuscularly administered 15(S) 15 methyl prostaglandin E2 methyl ester for induction of artificial abortion.
Topics: Abortion, Induced; Adolescent; Adult; Aspirin; Atropine; Diarrhea; Diphenoxylate; Drug Administratio | 1975 |
Pharmacokinetics and safety of prochlorperazine in paediatric patients receiving cancer chemotherapy.
Topics: Adolescent; Child; Child, Preschool; Cisplatin; Cyclophosphamide; Humans; Infant; Neoplasms; Prochlo | 1992 |
Acute and delayed emesis after cisplatin-based regimen: description and prevention.
Topics: Acute Disease; Antiemetics; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Humans; Lora | 1991 |
A dose finding study of prochlorperazine as an antiemetic for cancer chemotherapy.
Topics: Antiemetics; Antineoplastic Agents; Drug Evaluation; Humans; Prochlorperazine; Vomiting | 1989 |
Diplopia due to phenothiazine toxicity.
Topics: Adolescent; Diplopia; Female; Humans; Prochlorperazine; Torticollis; Vomiting | 1989 |
Vomiting after ophthalmic surgery. Effects of intra-operative antiemetics and postoperative oral fluid restriction.
Topics: Adult; Antiemetics; Drinking; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Ophthal | 1987 |
Prochlorperazine and vomiting after eye surgery.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Droperidol; Drug Therapy, Combination; Humans; Inf | 1987 |
Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion.
Topics: Adult; Aged; Brain Neoplasms; Carmustine; Carotid Arteries; Diazepam; Droperidol; Drug Therapy, Comb | 1986 |
The antiemetic activity of droperidol administered by intramuscular injection during cisplatin chemotherapy: a pilot study.
Topics: Adult; Aged; Cisplatin; Droperidol; Dysgerminoma; Humans; Injections, Intramuscular; Middle Aged; Pi | 1985 |
[Cisplatin drug therapy. Antiemetic treatment. Experiences with the use of high-dose metoclopramide combined with chlopromazine and prochlorperazine].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Dose-Response Relat | 1985 |
High-dose intravenous metoclopramide and intermittent intramuscular prochlorperazine and diazepam in the management of emesis induced by cis-dichlorodiammineplatinum.
Topics: Antiemetics; Cisplatin; Diazepam; Drug Therapy, Combination; Humans; Injections, Intramuscular; Meto | 1985 |
Reaction to prochlorperazine?
Topics: Adolescent; Child; Diphenhydramine; Female; Humans; Male; Movement Disorders; Prochlorperazine; Spas | 1969 |
Intra-amniotic administration of prostaglandin F 2 for induction of therapeutic abortion. A comparison of four dosage schedules.
Topics: Abortion, Therapeutic; Adolescent; Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female; | 1972 |
Intra-amniotic administration of prostaglandin F 2 to induce therapeutic abortion. Efficacy and tolerance of two dosage schedules.
Topics: Abortion, Therapeutic; Amniotic Fluid; Blood Pressure; Body Temperature; Female; Heart Rate; Humans; | 1972 |
Antinauseant drugs in treatment of epidemic or virus gastritis?
Topics: Adolescent; Female; Gastritis; Humans; Prochlorperazine; Virus Diseases; Vomiting | 1970 |