prochlorperazine has been researched along with Recrudescence in 9 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache." | 7.70 | Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache. ( Fuh, JL; Juang, KD; Lu, SR; Wang, SJ, 2000) |
| "To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache." | 3.70 | Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache. ( Fuh, JL; Juang, KD; Lu, SR; Wang, SJ, 2000) |
| "In this double-blind, double-dummy, randomised, parallel group, multicentre study, the efficacy of dosing and re-dosing of a fixed combination of indomethacin, prochlorperazine and caffeine (Indoprocaf) was compared with encapsulated sumatriptan in the acute treatment of two migraine attacks." | 2.73 | Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu ( Cerbo, R; Del Bene, E; Ferrari, A; Genco, S; Grazioli, I; Martelletti, P; Nappi, G; Pinessi, L; Sandrini, G; Sarchielli, P; Tamburro, P; Uslenghi, C; Zanchin, G, 2007) |
| "One hundred twelve patients with migraine with or without aura according to the diagnostic criteria of the International Headache Society were randomized to treat 2 migraine attacks with a fixed combination of indomethacin, prochlorperazine, and caffeine and 2 migraine attacks with sumatriptan." | 2.71 | Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial. ( Aloisio, A; Del Bianco, P; Di Monda, V; Fonzari, M; Grazioli, I; Nicolodi, M; Sicuteri, F; Uslenghi, C; Vecchiet, L, 2003) |
| " Antiemetic effect of prochlorperazine (PCZ) is diminished by its low bioavailability owing to a significant gastric and hepatic first pass effect." | 2.69 | Evaluation of prochlorperazine buccal tablets (Bukatel) and metoclopramide oral tablets in the treatment of acute emesis. ( Chaudhary, A; Sharma, DR; Singh, S, 1999) |
| "The majority of children with migraines are successfully discharged from the ED and only 1 in 18 required a revisit within 3 days." | 1.42 | A comparison of acute treatment regimens for migraine in the emergency department. ( Bachur, RG; Monuteaux, MC; Neuman, MI, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachur, RG | 1 |
| Monuteaux, MC | 1 |
| Neuman, MI | 1 |
| Trottier, ED | 1 |
| Bailey, B | 1 |
| Lucas, N | 1 |
| Lortie, A | 1 |
| Di Monda, V | 1 |
| Nicolodi, M | 1 |
| Aloisio, A | 1 |
| Del Bianco, P | 1 |
| Fonzari, M | 1 |
| Grazioli, I | 2 |
| Uslenghi, C | 2 |
| Vecchiet, L | 1 |
| Sicuteri, F | 1 |
| Sandrini, G | 1 |
| Cerbo, R | 1 |
| Del Bene, E | 1 |
| Ferrari, A | 1 |
| Genco, S | 1 |
| Martelletti, P | 1 |
| Nappi, G | 1 |
| Pinessi, L | 1 |
| Sarchielli, P | 1 |
| Tamburro, P | 1 |
| Zanchin, G | 1 |
| Shimada, T | 1 |
| Higashi, K | 1 |
| Kimura, K | 1 |
| Shido, T | 1 |
| Tomita, K | 1 |
| Singh, S | 1 |
| Sharma, DR | 1 |
| Chaudhary, A | 1 |
| Shivkumar, K | 1 |
| Lu, SR | 1 |
| Fuh, JL | 1 |
| Juang, KD | 1 |
| Wang, SJ | 1 |
| Davis, JM | 1 |
| Gosenfeld, L | 1 |
| Tsai, CC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blinded Study Comparing Use of Prochlorperazine Versus Prochlorperazine and Ketorolac in the Treatment of Pediatric Migraine in the Emergency Department[NCT01534806] | Phase 4 | 0 participants (Actual) | Interventional | 2012-01-31 | Withdrawn (stopped due to Drug is backordered;) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for prochlorperazine and Recrudescence
| Article | Year |
|---|---|
Maintenance antipsychotic drugs do prevent relapse: a reply to Tobias and MacDonald.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Drug Evaluation; Fluphenazine; Humans; Perphe | 1976 |
4 trials available for prochlorperazine and Recrudescence
| Article | Year |
|---|---|
Prochlorperazine in children with migraine: a look at its effectiveness and rate of akathisia.
Topics: Adolescent; Akathisia, Drug-Induced; Child; Diphenhydramine; Dopamine Antagonists; Drug Therapy, Com | 2012 |
Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Caffeine; Central Nervou | 2003 |
Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu
Topics: Administration, Oral; Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combination | 2007 |
Evaluation of prochlorperazine buccal tablets (Bukatel) and metoclopramide oral tablets in the treatment of acute emesis.
Topics: Administration, Buccal; Administration, Oral; Adolescent; Adult; Aged; Antiemetics; Cholecystectomy; | 1999 |
4 other studies available for prochlorperazine and Recrudescence
| Article | Year |
|---|---|
A comparison of acute treatment regimens for migraine in the emergency department.
Topics: Adolescent; Analgesics; Analgesics, Opioid; Child; Comparative Effectiveness Research; Diphenhydrami | 2015 |
Syndrome of inappropriate antidiuresis seen twice in eight years.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Atrial Natriuretic Factor; Diur | 1995 |
Images in cardiovascular medicine. Labile repolarization from "cell to bedside".
Topics: Anti-Arrhythmia Agents; Antiemetics; Electric Countershock; Female; Humans; Long QT Syndrome; Middle | 2000 |
Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache.
Topics: Adult; Analgesics; Antipsychotic Agents; Female; Follow-Up Studies; Headache; Humans; Infusions, Int | 2000 |