prochlorperazine has been researched along with Pregnancy in 65 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| "The use of ondansetron in the ED for nausea and vomiting of pregnancy was associated with similar mean time from administration to disposition as other antiemetics." | 3.81 | Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting. ( Gray, R; Lopes, V; Matteson, KA; Mayhall, EA, 2015) |
| " In 84 patients (control group), no prophylactic antiemetic or antidiarrheal drugs were administered, while in 46 patients (study group), an antiemetic (prochlorperazine) and an antidiarrheal (diphenoxylate hydrochloride with atropine sulfate) drug were administered prophylactically before and during prostaglandin infusion." | 3.66 | Prophylaxis against prostaglandin-induced gastrointestinal side effects. ( Fahmy, K, 1981) |
| "Sixty gravidas 8 to 20 menstrual weeks' gestation were studied to evaluate (1) the efficacy of intramuscularly administered 15(S)-15-methyl prostaglandin F2alpha tromethamine (15(S)-Me-PGF2alpha) as an abortifacient; (2) the effectiveness of prochlorperazine and Lomotil for attenuation of vomiting and diarrhea; and (3) the practicability of augmenting this prostaglandin dose schedule with intracervical laminaria tents." | 3.65 | Evaluation of intramuscular 15(s)-15-methyl prostaglandin F2 alpha tromethamine salt for induction of abortion, medications to attenuate side effects, and intracervical laminaria tents. ( Brenner, WE; Dingfelder, JR; Gruber, W; Staurovsky, LG; Wells, JS, 1976) |
| "Vomiting was significantly more frequent in the placebo-treated group [0." | 2.64 | A controlled trial of antiemetics in abortion by PGF2alpha and laminaria. ( Federschneider, JM; Kaul, AF; Stubblefield, PG, 1978) |
| "Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment." | 1.72 | 2022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022) |
| "Fenfluramine was intermediate in its effects on reproduction and growth and had behavioral effects that were revealed in tests of preweaning development." | 1.26 | Psychotropic drugs as behavioral teratogens. ( Brunner, RL; Butcher, RE; Vorhees, CV, 1979) |
| "A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth." | 1.25 | Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (81.54) | 18.7374 |
| 1990's | 3 (4.62) | 18.2507 |
| 2000's | 4 (6.15) | 29.6817 |
| 2010's | 4 (6.15) | 24.3611 |
| 2020's | 1 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Lau, CI | 1 |
| Wang, YF | 1 |
| Lehmann, AS | 1 |
| Renbarger, JL | 1 |
| McCormick, CL | 1 |
| Topletz, AR | 1 |
| Rouse, C | 1 |
| Haas, DM | 1 |
| Furyk, JS | 1 |
| Meek, R | 1 |
| McKenzie, S | 1 |
| Mayhall, EA | 1 |
| Gray, R | 1 |
| Lopes, V | 1 |
| Matteson, KA | 1 |
| Coralic, Z | 1 |
| Kim, AS | 1 |
| Vinson, DR | 1 |
| Rozen, TD | 1 |
| SULLIVAN, CL | 1 |
| PRICE, NJ | 1 |
| CAZZOLA, D | 1 |
| ONGHENA, G | 1 |
| DE MARCHI, A | 1 |
| GATTO, A | 1 |
| ROGERS, JB | 1 |
| BEGHI, Q | 1 |
| MCQUEEN, EG | 1 |
| HANSON, IR | 1 |
| BAKER, RL | 1 |
| GALLAHER, JP | 1 |
| DOWLING, HF | 1 |
| LEPPER, MH | 1 |
| SYLVESTER, WR | 1 |
| WINBERG, J | 2 |
| GATLING, RR | 1 |
| MORRIS, RH | 1 |
| VASSALLI, P | 1 |
| BELLER, FK | 1 |
| MCCLUSKEY, RT | 1 |
| ASTRACHAN, JM | 1 |
| KAPPELMAN, MD | 1 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| VIGLIONE, JP | 1 |
| Beirne, M | 1 |
| Fenton, J | 1 |
| Reis, M | 1 |
| Källén, B | 1 |
| Fahmy, K | 1 |
| Chan, SC | 1 |
| Lo, JR | 1 |
| Wong, KC | 1 |
| Haynes, SR | 1 |
| Davidson, I | 1 |
| Allsop, JR | 1 |
| Dutton, DA | 1 |
| Magee, LA | 1 |
| Redman, CW | 1 |
| Rise, A | 1 |
| Kaul, AF | 1 |
| Federschneider, JM | 1 |
| Stubblefield, PG | 1 |
| Ho, CK | 1 |
| Kaufman, RL | 1 |
| McAlister, WH | 1 |
| Jarvik, ME | 1 |
| Vorhees, CV | 1 |
| Brunner, RL | 1 |
| Butcher, RE | 1 |
| Milkovich, L | 1 |
| van den Berg, BJ | 1 |
| Gruber, W | 1 |
| Brenner, WE | 5 |
| Staurovsky, LG | 4 |
| Dingfelder, JR | 1 |
| Wells, JS | 1 |
| Wolstenholme, WW | 1 |
| Gautieri, RF | 1 |
| Grimes, DA | 1 |
| Dingfelder, R | 1 |
| Wortman, J | 1 |
| Lauersen, NH | 2 |
| Wilson, KH | 1 |
| Brambati, B | 1 |
| Lanzani, A | 1 |
| Sanchioni, L | 1 |
| Tului, L | 1 |
| Platt, JE | 1 |
| Friedhoff, AJ | 1 |
| Broman, SH | 1 |
| Bond, RN | 1 |
| Laska, E | 1 |
| Lin, SP | 1 |
| Rafla, N | 1 |
| Král, A | 1 |
| Schwarzová, K | 1 |
| Hendricks, CH | 3 |
| Braaksma, JT | 3 |
| Fishburne, JI | 3 |
| Csapo, AI | 1 |
| Kivikoski, A | 1 |
| Wiest, WG | 1 |
| Mueller, RA | 1 |
| Hoffer, JL | 1 |
| Kroncke, FG | 1 |
| Staurovsky, L | 1 |
| Alexander, GJ | 1 |
| Machiz, S | 1 |
| Alexander, RB | 1 |
| Hill, RM | 1 |
| Verniaud, WM | 1 |
| Horning, MG | 1 |
| McCulley, LB | 1 |
| Morgan, NF | 1 |
| Marks, PA | 1 |
| Kammeraad, LA | 1 |
| Papp, JP | 1 |
| Conrad, P | 1 |
| Farkas, G | 2 |
| Lebensztejn, W | 1 |
| Jackiewicz, H | 1 |
| Freeman, R | 1 |
| Gauron, EF | 1 |
| Rowley, VN | 1 |
| Morra, C | 1 |
| Lanza, A | 1 |
| Marbury, BE | 1 |
| Borgstedt, AD | 1 |
| Rosen, MG | 1 |
| Failor, HJ | 1 |
| Huffman, MW | 1 |
| Berger, PA | 1 |
| Mackinnon, AM | 1 |
| Baron, A | 1 |
| Krzysztoniowa, Z | 1 |
| Reszczynski, A | 1 |
6 trials available for prochlorperazine and Pregnancy
| Article | Year |
|---|---|
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
Vomiting after anaesthesia for termination of pregnancy in Chinese.
Topics: Abortion, Induced; Anesthesia, Obstetrical; China; Ethnicity; Female; Humans; Metoclopramide; Preane | 1983 |
Comparison of epidural methadone with epidural diamorphine for analgesia following caesarean section.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Cesarean Section; Double-Blind Method; Female; Heroin; | 1993 |
An N-of-1 trial for treatment of hyperemesis gravidarum.
Topics: Adult; Antiemetics; Ascorbic Acid; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hy | 1996 |
A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.
Topics: Abortion, Induced; Adolescent; Adult; Amnion; Analgesics, Opioid; Antiemetics; Clinical Trials as To | 1978 |
An evaluation of the teratogenicity of certain antinauseant drugs.
Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylami | 1976 |
59 other studies available for prochlorperazine and Pregnancy
| Article | Year |
|---|---|
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G | 2022 |
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
Topics: Adult; Antiemetics; Female; Humans; Metoclopramide; Morning Sickness; Ondansetron; Pilot Projects; P | 2013 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra | 2014 |
Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting.
Topics: Adult; Antiemetics; Cohort Studies; Emergency Service, Hospital; Female; Humans; Hypotension, Orthos | 2015 |
Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
Topics: Adult; Diphenhydramine; Dystonia; Emergency Medicine; Female; Humans; Hyperemesis Gravidarum; Infusi | 2015 |
Aborting a prolonged migrainous aura with intravenous prochlorperazine and magnesium sulfate.
Topics: Adult; Dopamine Antagonists; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Mag | 2003 |
Prochlorperazine for the treatment of nausea and vomiting of early pregnancy.
Topics: Female; Humans; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Prochlorperazine; Vomiti | 1958 |
The treatment of nausea and vomiting of pregnancy with prochlorperazine.
Topics: Female; Humans; Nausea; Phenothiazines; Pregnancy; Pregnancy Complications; Prochlorperazine; Vomiti | 1958 |
[Use of prochlorperazine in obstetrics and gynecology].
Topics: Female; Genital Diseases, Female; Gynecology; Humans; Obstetrics; Phenothiazines; Pregnancy; Pregnan | 1959 |
[Clinical study of prochlorperazine in hyperemesis gravidarum].
Topics: Biomedical Research; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Prochlorperazine | 1960 |
[Prochlorperazine in obstetrics and gynecology].
Topics: Female; Genitalia; Genitalia, Female; Gynecology; Humans; Neoplasms; Obstetrics; Pregnancy; Pregnanc | 1959 |
The grimacing syndrome. A report of two cases.
Topics: Female; Humans; Movement Disorders; Pregnancy; Pregnancy Complications; Prochlorperazine; Spasm; Syn | 1963 |
[PSYCHIATRIC USE OF SOME PSYCHOPHARMACOLOGICAL DRUGS IN PREGNANCY].
Topics: Chlordiazepoxide; Chlorpromazine; Fetus; Haloperidol; Imipramine; Isocarboxazid; Meprobamate; Nialam | 1963 |
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundi | 1963 |
PROBLEM WEIGHT GAIN IN "WANTED" VERSUS "UNWANTED" PREGNANCIES.
Topics: Amphetamine; Emotions; Female; Humans; Infant, Newborn; Obesity; Pregnancy; Pregnancy, Unwanted; Pro | 1963 |
HEPATIC REACTIONS TO TETRACYCLINE.
Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Child; Chloramphenicol; Chlortetracyc | 1964 |
NAUSEA AND VOMITING IN PREGNANCY.
Topics: Female; Humans; Hydroxyzine; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Toxicolog | 1964 |
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Ca | 1964 |
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
EFFECT OF NICOTINE ON CHICK EMBRYO.
Topics: Abnormalities, Drug-Induced; Chick Embryo; Cortisone; Epinephrine; Hematoma; Hemorrhage; Nicotine; N | 1964 |
IMMUNOFLUORESCENT STUDIES OF RENAL BIOPSIES IN THE DIAGNOSIS OF TOXEMIA OF PREGNANCY.
Topics: Adolescent; Biopsy; Blood Coagulation Tests; Female; Fibrinolysis; Fluorescent Antibody Technique; H | 1964 |
SEVERE PSYCHOLOGIC DISORDERS OF THE PUERPERIUM. A RECOMMENDED APPROACH FOR THE CLINICAL OBSTETRICIAN.
Topics: Bipolar Disorder; Child; Depression; Female; Humans; Iatrogenic Disease; Mental Disorders; Parent-Ch | 1965 |
Prochlorperazine in labor and delivery.
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Obstetrical; Female; Humans; Labor, Obs | 1962 |
Appetite control in pregnancy using combined prochlorperazine-dextroamphetamine.
Topics: Amphetamine; Amphetamines; Appetite; Appetite Regulation; Dextroamphetamine; Female; Obesity; Pregna | 1962 |
Acute dystonic reaction secondary to prochlorperazine use in the treatment of hyperemesis gravidarum.
Topics: Acute Disease; Adult; Antiemetics; Dystonia; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Proc | 2007 |
Maternal use of antipsychotics in early pregnancy and delivery outcome.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Antiemetics; Antipsychotic Agents; Cesarean Sec | 2008 |
Prophylaxis against prostaglandin-induced gastrointestinal side effects.
Topics: Abortion, Induced; Antiemetics; Atropine; Diarrhea; Dinoprost; Diphenoxylate; Drug Combinations; Fem | 1981 |
[Neuroleptics].
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenaz | 1976 |
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip | 1975 |
Necessary risks.
Topics: Animals; Antiemetics; Dogs; Dronabinol; Drug Industry; Drug-Related Side Effects and Adverse Reactio | 1979 |
Psychotropic drugs as behavioral teratogens.
Topics: Animals; Behavior, Animal; Brain Chemistry; Dextropropoxyphene; Disease Models, Animal; Female; Fenf | 1979 |
Evaluation of intramuscular 15(s)-15-methyl prostaglandin F2 alpha tromethamine salt for induction of abortion, medications to attenuate side effects, and intracervical laminaria tents.
Topics: Abortion, Induced; Adolescent; Adult; Blood Pressure; Body Temperature; Cervix Uteri; Diarrhea; Diph | 1976 |
Effect of certain drugs in perfused human placenta XII: autacoid antagonism by phenothiazines.
Topics: Angiotensin II; Blood Pressure; Bradykinin; Chlorpromazine; Female; Humans; In Vitro Techniques; Phe | 1976 |
Letter: Use of Lomotil.
Topics: Diarrhea; Female; Humans; Pregnancy; Prochlorperazine | 1975 |
The efficacy and safety of intramuscularly administered 15(S) 15 methyl prostaglandin E2 methyl ester for induction of artificial abortion.
Topics: Abortion, Induced; Adolescent; Adult; Aspirin; Atropine; Diarrhea; Diphenoxylate; Drug Administratio | 1975 |
Female sterilization using the culdoscope.
Topics: Anesthesia, Local; Atropine; Chlorpromazine; Culdoscopy; Female; Humans; Meperidine; Postoperative C | 1975 |
Induction of midtrimester abortion by serial intravaginal administration of 15(S)-15-methyl-prostaglandin F2alpha (THAM) suppositories.
Topics: Abortion, Induced; Adolescent; Adult; Diphenoxylate; Female; Humans; Parity; Pregnancy; Pregnancy Tr | 1975 |
Conjoined twins and in utero early exposure to prochlorperazine.
Topics: Abortion, Induced; Adult; Female; Humans; Pregnancy; Prochlorperazine; Twins, Conjoined | 1990 |
Effects of prenatal exposure to neuroleptic drugs on children's growth.
Topics: Antipsychotic Agents; Birth Weight; Body Height; Body Weight; Female; Growth; Humans; Infant, Newbor | 1988 |
Limb deformities associated with prochlorperazine.
Topics: Abnormalities, Drug-Induced; Female; Humans; Hyperemesis Gravidarum; Limb Deformities, Congenital; P | 1987 |
[Repeated dislocations of the lower jaw conditioned by orofacial spasms].
Topics: Adult; Female; Humans; Joint Dislocations; Mandible; Pregnancy; Pregnancy Complications; Prochlorper | 1974 |
Intra-amniotic administration of prostaglandin F 2 for induction of therapeutic abortion. A comparison of four dosage schedules.
Topics: Abortion, Therapeutic; Adolescent; Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female; | 1972 |
Massive initial prostaglandin impact in postconceptional therapy.
Topics: Abortion, Induced; Adult; Amniotic Fluid; Estradiol; Female; Humans; Hydroxyzine; Injections; Meperi | 1972 |
Changes in human plasma catecholamines and dopamine-beta-hydroxylase produced by prostaglandin F2 alpha.
Topics: Adult; Carbon Isotopes; Central Venous Pressure; Dopamine beta-Hydroxylase; Electrophoresis; Epineph | 1972 |
Intra-amniotic administration of prostaglandin F 2 to induce therapeutic abortion. Efficacy and tolerance of two dosage schedules.
Topics: Abortion, Therapeutic; Amniotic Fluid; Blood Pressure; Body Temperature; Female; Heart Rate; Humans; | 1972 |
Phenothiazine tranquillizers: effect of prolonged intake.
Topics: Animals; Birth Weight; Chemical and Drug Induced Liver Injury; Chlorpromazine; Ethionine; Female; Fe | 1972 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro | 1974 |
Intrahepatic cholestasis in hyperemesis gravidarum: a case report.
Topics: Cholestasis; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlorperazine | 1974 |
Effect of oxytocic agents on blood loss during first trimester suction curettage.
Topics: Abortion, Legal; Curettage; Ergonovine; Extraction, Obstetrical; Female; Humans; Methods; Oxytocin; | 1974 |
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec | 1971 |
[Cerebral disorders in a pregnant woman due to acute stemetyl poisoning].
Topics: Adult; Female; Gestational Age; Humans; Neurologic Manifestations; Poisoning; Pregnancy; Pregnancy C | 1972 |
Limb deformities: possible association with drugs.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Arm; Female; Humans; Infant, Newborn; Leg; Male; Pregnan | 1972 |
Effects on offspring behavior of mothers' early chronic drug experience.
Topics: Animals; Animals, Newborn; Avoidance Learning; Breeding; Chlorpromazine; Conditioning, Psychological | 1969 |
[Recent etiopathogenetic concepts and new therapeutic trends in emesis gravidarum].
Topics: Acidosis; Adrenal Cortex Hormones; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlo | 1969 |
Anesthesia in abortions.
Topics: Abortion, Legal; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthesia, Obstetrical; Atropine; | 1971 |
Medication during labor correlated with behavior and EEG of the newborn.
Topics: Anesthesia, Obstetrical; Behavior; Electroencephalography; Female; Humans; Infant, Newborn; Meperidi | 1968 |
Dystonic reactions to phenothiazine drugs.
Topics: Adolescent; Adult; Female; Humans; Muscular Diseases; Phenothiazines; Postoperative Complications; P | 1965 |
"Stemetil" idiosyncrasy: a report of four cases.
Topics: Adult; Child; Child, Preschool; Drug Hypersensitivity; Female; Humans; Male; Neurologic Manifestatio | 1966 |
[Hyperkinetic attacks in pregnant women with prochlorperazine (stemetil)].
Topics: Adult; Female; Humans; Movement Disorders; Poland; Pregnancy; Pregnancy Complications; Prochlorperaz | 1966 |