Page last updated: 2024-11-03

prochlorperazine and Pernicious Vomiting of Pregnancy

prochlorperazine has been researched along with Pernicious Vomiting of Pregnancy in 11 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Research Excerpts

ExcerptRelevanceReference
"This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy."5.10Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003)
"A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth."1.25Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coralic, Z1
Kim, AS1
Vinson, DR1
ONGHENA, G1
Bsat, FA1
Hoffman, DE1
Seubert, DE1
Beirne, M1
Fenton, J1
Magee, LA1
Redman, CW1
Ho, CK1
Kaufman, RL1
McAlister, WH1
Milkovich, L1
van den Berg, BJ1
Rafla, N1
Marks, PA1
Kammeraad, LA1
Papp, JP1
Farkas, G2
Morra, C1
Lanza, A1

Trials

3 trials available for prochlorperazine and Pernicious Vomiting of Pregnancy

ArticleYear
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
    Journal of perinatology : official journal of the California Perinatal Association, 2003, Volume: 23, Issue:7

    Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid

2003
An N-of-1 trial for treatment of hyperemesis gravidarum.
    British journal of obstetrics and gynaecology, 1996, Volume: 103, Issue:5

    Topics: Adult; Antiemetics; Ascorbic Acid; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hy

1996
An evaluation of the teratogenicity of certain antinauseant drugs.
    American journal of obstetrics and gynecology, 1976, May-15, Volume: 125, Issue:2

    Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylami

1976

Other Studies

8 other studies available for prochlorperazine and Pernicious Vomiting of Pregnancy

ArticleYear
Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
    The western journal of emergency medicine, 2015, Volume: 16, Issue:4

    Topics: Adult; Diphenhydramine; Dystonia; Emergency Medicine; Female; Humans; Hyperemesis Gravidarum; Infusi

2015
[Clinical study of prochlorperazine in hyperemesis gravidarum].
    Bruxelles medical, 1960, Nov-06, Volume: 40

    Topics: Biomedical Research; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Prochlorperazine

1960
Acute dystonic reaction secondary to prochlorperazine use in the treatment of hyperemesis gravidarum.
    Irish journal of medical science, 2007, Volume: 176, Issue:1

    Topics: Acute Disease; Adult; Antiemetics; Dystonia; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Proc

2007
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip

1975
Limb deformities associated with prochlorperazine.
    American journal of obstetrics and gynecology, 1987, Volume: 156, Issue:6

    Topics: Abnormalities, Drug-Induced; Female; Humans; Hyperemesis Gravidarum; Limb Deformities, Congenital; P

1987
Intrahepatic cholestasis in hyperemesis gravidarum: a case report.
    Michigan medicine, 1974, Volume: 73, Issue:20

    Topics: Cholestasis; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlorperazine

1974
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
    Zentralblatt fur Gynakologie, 1971, Mar-06, Volume: 93, Issue:10

    Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec

1971
[Recent etiopathogenetic concepts and new therapeutic trends in emesis gravidarum].
    Minerva ginecologica, 1969, Jul-15, Volume: 21, Issue:13

    Topics: Acidosis; Adrenal Cortex Hormones; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlo

1969