Page last updated: 2024-11-03

prochlorperazine and Parkinson Disease, Secondary

prochlorperazine has been researched along with Parkinson Disease, Secondary in 13 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research Excerpts

ExcerptRelevanceReference
" Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18."2.64Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199012 (92.31)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sheppard, C1
Merlis, S1
Stephen, PJ1
Williamson, J1
Baker, FM1
Cook, P1
Sahoo, RN1
Mitra, GC1
Mohanty, PC1
Claveria, LE1
Teychenne, PF1
Calne, DB1
Haskayne, L1
Petrie, A1
Pallis, CA1
Lodge-Patch, IC1
Rodgers, C1
Bateman, DN3
Darling, WM1
Boys, R1
Rawlins, MD3
Edelstein, H1
Knight, RT1
Wilson, JA1
Smith, RG1
Fiorini, A1
Tallis, R1
Woodhouse, KW1
Simpson, JM1
Klawans, HL1
Bergen, D1
Bruyn, GW1

Reviews

1 review available for prochlorperazine and Parkinson Disease, Secondary

ArticleYear
Compazine complications: a review.
    Journal of the National Medical Association, 1981, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Antiemetics; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Dystonia; Female;

1981

Trials

1 trial available for prochlorperazine and Parkinson Disease, Secondary

ArticleYear
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes

1975

Other Studies

11 other studies available for prochlorperazine and Parkinson Disease, Secondary

ArticleYear
Drug-induced extrapyramidal symptoms: their incidence and treatment.
    The American journal of psychiatry, 1967, Volume: 123, Issue:7

    Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp

1967
Drug-induced parkinsonism in the elderly.
    Lancet (London, England), 1984, Nov-10, Volume: 2, Issue:8411

    Topics: Aged; Antipsychotic Agents; Diagnosis, Differential; Female; Humans; Parkinson Disease; Parkinson Di

1984
Irreversible drug induced parkinsonism (two case reports).
    The Journal of the Association of Physicians of India, 1975, Volume: 23, Issue:8

    Topics: Adult; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Phenothiazines; Prochlorperazine; Tr

1975
Extrapyramidal side effects of antiemetics presenting as psychiatric illness.
    General hospital psychiatry, 1992, Volume: 14, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Anxiety Disor

1992
Extrapyramidal reactions to metoclopramide and prochlorperazine.
    The Quarterly journal of medicine, 1989, Volume: 71, Issue:264

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Basal Ganglia Diseases; Child;

1989
Severe parkinsonism in two AIDS patients taking prochlorperazine.
    Lancet (London, England), 1987, Aug-08, Volume: 2, Issue:8554

    Topics: Acquired Immunodeficiency Syndrome; Adult; Humans; Male; Parkinson Disease, Secondary; Pneumonia, Pn

1987
Relation between elderly and AIDS patients with drug-induced Parkinson's disease.
    Lancet (London, England), 1987, Sep-19, Volume: 2, Issue:8560

    Topics: Acquired Immunodeficiency Syndrome; Aged; Humans; Parkinson Disease, Secondary; Prochlorperazine

1987
Prochlorperazine in the elderly.
    Lancet (London, England), 1988, Oct-08, Volume: 2, Issue:8615

    Topics: Aged; Humans; Parkinson Disease, Secondary; Prochlorperazine

1988
Prochlorperazine and the elderly.
    Lancet (London, England), 1988, Nov-19, Volume: 2, Issue:8621

    Topics: Age Factors; Aged; Humans; Middle Aged; Parkinson Disease, Secondary; Prochlorperazine

1988
Extrapyramidal reactions to prochlorperazine and haloperidol in the United Kingdom.
    The Quarterly journal of medicine, 1986, Volume: 59, Issue:230

    Topics: Adolescent; Adult; Age Factors; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Dystonia; Female;

1986
Prolonged drug-induced Parkinsonism.
    Confinia neurologica, 1973, Volume: 35, Issue:6

    Topics: Adult; Antipsychotic Agents; Female; Humans; Middle Aged; Parkinson Disease, Secondary; Prochlorpera

1973