prochlorperazine has been researched along with Pain in 12 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compare the effectiveness of intravenous ketorolac and intravenous prochlorperazine in the treatment of pediatric migraine headaches." | 9.11 | Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac. ( Anderson, AC; Brousseau, DC; Duffy, SJ; Linakis, JG, 2004) |
| "The incidence of nausea induced by oxycodone with prochlorperazine was 18." | 7.81 | Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients. ( Aoki, Y; Kanazawa, Y; Uchida, E; Yamada, T, 2015) |
| "Indomethacin was quicker acting, probably due to the intravenous route of administration." | 6.65 | A comparative study on the analgesic effects of indomethacin and hydromorphinechloride-atropine in acute, ureteral-stone pain. ( Berger, T; Rentzhog, L; Udén, P, 1983) |
| "We compare the effectiveness of intravenous ketorolac and intravenous prochlorperazine in the treatment of pediatric migraine headaches." | 5.11 | Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac. ( Anderson, AC; Brousseau, DC; Duffy, SJ; Linakis, JG, 2004) |
| "The incidence of nausea induced by oxycodone with prochlorperazine was 18." | 3.81 | Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients. ( Aoki, Y; Kanazawa, Y; Uchida, E; Yamada, T, 2015) |
| "Indomethacin was quicker acting, probably due to the intravenous route of administration." | 2.65 | A comparative study on the analgesic effects of indomethacin and hydromorphinechloride-atropine in acute, ureteral-stone pain. ( Berger, T; Rentzhog, L; Udén, P, 1983) |
| "Vomiting was significantly more frequent in the placebo-treated group [0." | 2.64 | A controlled trial of antiemetics in abortion by PGF2alpha and laminaria. ( Federschneider, JM; Kaul, AF; Stubblefield, PG, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chessman, AW | 1 |
| Yamada, T | 1 |
| Kanazawa, Y | 1 |
| Aoki, Y | 1 |
| Uchida, E | 1 |
| Tsukuura, H | 1 |
| Ando, Y | 1 |
| Gyawali, B | 1 |
| Matsumoto, M | 1 |
| Sugishita, M | 1 |
| Honda, K | 1 |
| Urakawa, H | 1 |
| Maeda, O | 1 |
| Hasegawa, Y | 1 |
| DUNDEE, JW | 1 |
| LOVE, WJ | 1 |
| MOORE, J | 1 |
| KASSLER, HM | 1 |
| Brousseau, DC | 1 |
| Duffy, SJ | 1 |
| Anderson, AC | 1 |
| Linakis, JG | 1 |
| Udén, P | 1 |
| Rentzhog, L | 1 |
| Berger, T | 1 |
| Trinkle, R | 1 |
| Kaul, AF | 1 |
| Federschneider, JM | 1 |
| Stubblefield, PG | 1 |
| Yosselson-Superstine, S | 1 |
| Lipman, AG | 1 |
| Sanders, SH | 1 |
| Brenner, WE | 2 |
| Hendricks, CH | 2 |
| Braaksma, JT | 2 |
| Fishburne, JI | 2 |
| Staurovsky, LG | 1 |
| Kroncke, FG | 1 |
| Staurovsky, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department[NCT03576820] | Phase 3 | 50 participants (Anticipated) | Interventional | 2018-10-15 | Recruiting | ||
| A Randomized Double Blinded Study Comparing Use of Prochlorperazine Versus Prochlorperazine and Ketorolac in the Treatment of Pediatric Migraine in the Emergency Department[NCT01534806] | Phase 4 | 0 participants (Actual) | Interventional | 2012-01-31 | Withdrawn (stopped due to Drug is backordered;) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for prochlorperazine and Pain
| Article | Year |
|---|---|
Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Double-Blind Method; Female | 2004 |
Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Double-Blind Method; Female | 2004 |
Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Double-Blind Method; Female | 2004 |
Treatment of pediatric migraine headaches: a randomized, double-blind trial of prochlorperazine versus ketorolac.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Double-Blind Method; Female | 2004 |
A comparative study on the analgesic effects of indomethacin and hydromorphinechloride-atropine in acute, ureteral-stone pain.
Topics: Adult; Analgesics; Atropine; Dihydromorphine; Humans; Indomethacin; Injections, Intravenous; Injecti | 1983 |
A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.
Topics: Abortion, Induced; Adolescent; Adult; Amnion; Analgesics, Opioid; Antiemetics; Clinical Trials as To | 1978 |
Adjunctive antianxiety agents in the management of chronic pain.
Topics: Adult; Aged; Analgesics; Anti-Anxiety Agents; Arthritis; Chlordiazepoxide; Chronic Disease; Double-B | 1985 |
8 other studies available for prochlorperazine and Pain
| Article | Year |
|---|---|
IV prochlorperazine + diphenhydramine improved migraine pain relief more than IV hydromorphone in the ED.
Topics: Diphenhydramine; Humans; Hydromorphone; Migraine Disorders; Pain; Prochlorperazine | 2018 |
Incidence of nausea and vomiting induced by oxycodone administered with prochlorperazine in Japanese cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Female; Humans; Incidence; Japan; M | 2015 |
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys; | 2015 |
ALTERATIONS IN RESPONSE TO SOMATIC PAIN ASSOCIATED WITH ANAESTHESIA. XV. FURTHER STUDIES WITH PHENOTHIAZINE DERIVATIVES AND SIMILAR DRUGS.
Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Antiemetics; Antipyretics; Chlorpromazine; Chlorpr | 1963 |
THE NECK-FACE SYNDROME FOLLOWING THE USE OF PHENOTHIAZINE DRUGS.
Topics: Chlorpromazine; Face; Neck; Pain; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Prom | 1964 |
Compatibility of hydromorphone and prochlorperazine, and irritation due to subcutaneous prochlorperazine infusion.
Topics: Analgesics, Opioid; Antiemetics; Breast Neoplasms; Drug Incompatibility; Female; Humans; Hydromorpho | 1997 |
Intra-amniotic administration of prostaglandin F 2 for induction of therapeutic abortion. A comparison of four dosage schedules.
Topics: Abortion, Therapeutic; Adolescent; Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female; | 1972 |
Intra-amniotic administration of prostaglandin F 2 to induce therapeutic abortion. Efficacy and tolerance of two dosage schedules.
Topics: Abortion, Therapeutic; Amniotic Fluid; Blood Pressure; Body Temperature; Female; Heart Rate; Humans; | 1972 |