Compounds > prochlorperazine
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prochlorperazine and Movement Disorders

prochlorperazine has been researched along with Movement Disorders in 23 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
" Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18."2.64Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975)
"Fenfluramine was intermediate in its effects on reproduction and growth and had behavioral effects that were revealed in tests of preweaning development."1.26Psychotropic drugs as behavioral teratogens. ( Brunner, RL; Butcher, RE; Vorhees, CV, 1979)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199022 (95.65)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendhekar, DN1
Andrade, C1
CHRISTIAN, CD1
PAULSON, G1
GERAUD, J1
RASCOL, A1
ROGERS, JB1
POKRAS, NM1
KINGSBURY, BC1
HUNTER, R1
EARL, CJ1
THRONICROFT, S1
MARZUOLI, U1
GRASSANO, MC1
RUBINO, R1
Weitzman, DO1
Rosfnfeld, C1
Korenyl, C1
Whittier, JR1
Claveria, LE1
Teychenne, PF1
Calne, DB1
Haskayne, L1
Petrie, A1
Pallis, CA1
Lodge-Patch, IC1
Vorhees, CV1
Brunner, RL1
Butcher, RE1
Kamen, S1
Marcotte, DB1
Berk, BZ1
Hussey, HH1
Markham, CH1
Klawans, HL1
Bergen, D1
Bruyn, GW1
Paulson, GW1
Schnell, RG1
Bush, RT1
Richter, HR1
Briellmann, A1
Gurovich, IIa1
Grossman, LA1
Davidovich, E1
Kaplan, HJ1
Baron, A1
Krzysztoniowa, Z1
Reszczynski, A1

Trials

1 trial available for prochlorperazine and Movement Disorders

ArticleYear
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes

1975

Other Studies

22 other studies available for prochlorperazine and Movement Disorders

ArticleYear
Prochlorperazine-induced tardive dystonia and its worsening with clozapine in a non-mentally ill patient with migraine.
    The Annals of pharmacotherapy, 2011, Volume: 45, Issue:4

    Topics: Adult; Clozapine; Humans; Male; Migraine Disorders; Movement Disorders; Prochlorperazine

2011
Severe motility disturbance after small doses of prochlorperazine.
    The New England journal of medicine, 1958, Oct-23, Volume: 259, Issue:17

    Topics: Humans; Movement Disorders; Phenothiazines; Prochlorperazine

1958
[2 Observations of nervous accidents due to prochlorperazine (presence of the Babinski sing)].
    Toulouse medical, 1959, Volume: 60

    Topics: Accidents; Anxiety; Humans; Movement; Movement Disorders; Prochlorperazine

1959
The grimacing syndrome. A report of two cases.
    The Practitioner, 1963, Volume: 190

    Topics: Female; Humans; Movement Disorders; Pregnancy; Pregnancy Complications; Prochlorperazine; Spasm; Syn

1963
EXTRAPYRAMIDAL REACTIONS TO PROCHLORPERAZINE AND SIMILAR ANTIEMETIC DRUGS.
    Oral surgery, oral medicine, and oral pathology, 1963, Volume: 16

    Topics: Antiemetics; Extrapyramidal Tracts; Humans; Movement Disorders; Postoperative Complications; Prochlo

1963
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Brain; Brain Damage, Chronic; Brain Diseases; Chlorpromazine; Chorea; Diagnosis, Differential; Elect

1964
[EXTRAPYRAMIDAL SYNDROME WITH SUBINTRANT OCULOGYRIC CRISES DUE TO PROCHLORPEMAZINE THERAPY. APROPOS OF A CASE].
    Minerva medica, 1965, Jan-13, Volume: 56

    Topics: Basal Ganglia Diseases; Extrapyramidal Tracts; Eye Movements; Humans; Influenza, Human; Movement Dis

1965
Quantification of chorea in Huntington's disease by power spectral analysis.
    Diseases of the nervous system, 1976, Volume: 37, Issue:5

    Topics: Adult; Aged; Diazepam; Haloperidol; Humans; Huntington Disease; Mesoridazine; Methods; Middle Aged;

1976
Psychotropic drugs as behavioral teratogens.
    Science (New York, N.Y.), 1979, Sep-21, Volume: 205, Issue:4412

    Topics: Animals; Behavior, Animal; Brain Chemistry; Dextropropoxyphene; Disease Models, Animal; Female; Fenf

1979
Tardive dyskinesia. A significant syndrome for geriatric dentistry.
    Oral surgery, oral medicine, and oral pathology, 1975, Volume: 39, Issue:1

    Topics: Aged; Arteriosclerosis; Bruxism; Chlorpromazine; Dementia; Denture, Complete; Depression; Depressive

1975
Neuroleptics and neurologic reactions.
    Southern medical journal, 1973, Volume: 66, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Athetosis; Basal Ganglia Diseases; Female; Humans; Mesorida

1973
Drug-induced extrapyramidal symptoms. A cooperative study.
    JAMA, 1973, May-07, Volume: 224, Issue:6

    Topics: Antidepressive Agents; Antipsychotic Agents; Basal Ganglia Diseases; Butyrophenones; Chlorpromazine;

1973
Reaction to prochlorperazine?
    Lancet (London, England), 1969, Apr-12, Volume: 1, Issue:7598

    Topics: Adolescent; Child; Diphenhydramine; Female; Humans; Male; Movement Disorders; Prochlorperazine; Spas

1969
Editorial: Tardive dyskinesias.
    JAMA, 1974, May-20, Volume: 228, Issue:8

    Topics: Adult; Age Factors; Aged; Anxiety Disorders; Chlorpromazine; Chronic Disease; Female; Gastritis; Hum

1974
The "on-off" side effect of L-DOPA.
    Advances in neurology, 1974, Volume: 5

    Topics: Age Factors; Amitriptyline; Aromatic Amino Acid Decarboxylase Inhibitors; Athetosis; Carbidopa; Cate

1974
Neuroleptic-induced tardiave dyskinesias in nonpsychotic patients.
    Archives of neurology, 1974, Volume: 30, Issue:4

    Topics: Adult; Aged; Anxiety Disorders; Chlorpromazine; Female; Gastritis; Humans; Male; Middle Aged; Moveme

1974
Drug-induced dyskinesia treated with intravenous diazepam.
    The Journal of the Florida Medical Association, 1972, Volume: 59, Issue:1

    Topics: Adolescent; Diazepam; Female; Humans; Injections, Intravenous; Movement Disorders; Prochlorperazine

1972
Acute reactions to prochlorperazine ("Stemetil") in children. A report of four cases.
    The New Zealand medical journal, 1966, Volume: 65, Issue:404

    Topics: Child, Preschool; Diagnosis, Differential; Extrapyramidal Tracts; Female; Humans; Infant; Male; Meni

1966
[Acute dyskinesia following short-term antiemetic medication].
    Schweizerische medizinische Wochenschrift, 1969, Jul-26, Volume: 99, Issue:31

    Topics: Acute Disease; Adult; Diagnosis, Differential; Female; Humans; Movement Disorders; Prochlorperazine;

1969
[Transitory exacerbations arising during the course of neuroleptic therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:6

    Topics: Adult; Catatonia; Extrapyramidal Tracts; Humans; Movement Disorders; Paranoid Disorders; Prochlorper

1970
Extrapyramidal reactions, tranquilizers, and diagnostic difficulties.
    Journal of the Tennessee Medical Association, 1966, Volume: 59, Issue:1

    Topics: Adolescent; Diagnosis, Differential; Extrapyramidal Tracts; Female; Humans; Hysteria; Male; Movement

1966
[Hyperkinetic attacks in pregnant women with prochlorperazine (stemetil)].
    Revue francaise de gynecologie et d'obstetrique, 1966, Volume: 61, Issue:11

    Topics: Adult; Female; Humans; Movement Disorders; Poland; Pregnancy; Pregnancy Complications; Prochlorperaz

1966