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prochlorperazine and Motion Sickness

prochlorperazine has been researched along with Motion Sickness in 12 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Motion Sickness: Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness.

Research Excerpts

ExcerptRelevanceReference
"We studied the efficacy and safety of intravenous ondansetron 4 mg for the prevention of postoperative nausea and vomiting after minor gynaecological laparoscopic surgery in Oriental women."9.07Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. ( Chen, PP; Critchley, LA; Gin, TA; Ray, AK; Rowbottom, YM; Suen, TK, 1994)
"L-sulpiride, at a dose of 4 mg/kg, essentially abolished motion-induced emesis in a group of 6 squirrel monkeys undergoing horizontal rotation at 25 rpm, a terrestrial model of space motion sickness (SMS)."7.67The anti-emetic properties of 1-sulpiride in a ground-based model of space motion sickness. ( Brizzee, KR; Miller, JD, 1987)
"We studied the efficacy and safety of intravenous ondansetron 4 mg for the prevention of postoperative nausea and vomiting after minor gynaecological laparoscopic surgery in Oriental women."5.07Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery. ( Chen, PP; Critchley, LA; Gin, TA; Ray, AK; Rowbottom, YM; Suen, TK, 1994)
"Flunarizine is a calcium antagonist which has proved clinically useful in controlling chronic vertigo."5.06Calcium antagonists in the prevention of motion sickness. ( Boothby, G; Lee, JA; Watson, LA, 1986)
"L-sulpiride, at a dose of 4 mg/kg, essentially abolished motion-induced emesis in a group of 6 squirrel monkeys undergoing horizontal rotation at 25 rpm, a terrestrial model of space motion sickness (SMS)."3.67The anti-emetic properties of 1-sulpiride in a ground-based model of space motion sickness. ( Brizzee, KR; Miller, JD, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BACKENSTOE, GS1
WHEELER, WL1
HOWLAND, JM1
SMITH, W1
CORSO, JE1
WOOD, CD4
GRAYBIEL, A5
MCDONOUGH, RG1
KENNEDY, RS2
Deane, FR1
Suen, TK1
Gin, TA1
Chen, PP1
Rowbottom, YM1
Critchley, LA1
Ray, AK1
Lee, JA1
Watson, LA1
Boothby, G1
Miller, JD1
Brizzee, KR1
Borghesan, C1
Caporale, R1
Benson, AJ1

Trials

6 trials available for prochlorperazine and Motion Sickness

ArticleYear
Effect of drugs in altering susceptibility to motion sickness in aerobatics and the slow rotation room.
    Aerospace medicine, 1967, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Aerospace Medicine; Antiemetics; Cyclizine; Dextroamphetamine; Humans; Male; Mecl

1967
Ondansetron 4 mg for the prevention of nausea and vomiting after minor laparoscopic gynaecological surgery.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Double-Blind Method; Female; Follow-Up Studi

1994
Calcium antagonists in the prevention of motion sickness.
    Aviation, space, and environmental medicine, 1986, Volume: 57, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Double-Blind Method; Electro

1986
Evaluation of sixteen anti-motion sickness drugs under controlled laboratory conditions.
    Aerospace medicine, 1968, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Amphetamine; Antiemetics; Benzamides; Chlorpromazine; Clinical Trials as Topic; C

1968
Effect of diphenidol and prochlorperazine on semicircular canal function in man.
    Aerospace medicine, 1969, Volume: 40, Issue:6

    Topics: Adult; Antiemetics; Clinical Trials as Topic; Female; Humans; Male; Motion Sickness; Piperidines; Pl

1969
A comparison of effectiveness of some antimotion sickness drugs using recommended and larger than recommended doses as tested in the slow rotation room. NSAM-945.
    Research report. Naval School of Aviation Medicine (U.S.), 1965

    Topics: Benzamides; Clinical Trials as Topic; Dextroamphetamine; Humans; Male; Meclizine; Motion Sickness; P

1965

Other Studies

6 other studies available for prochlorperazine and Motion Sickness

ArticleYear
Prochlorperazine in airsickness.
    Pennsylvania medical journal (1928), 1959, Volume: 62

    Topics: Humans; Motion Sickness; Prochlorperazine

1959
The use of prochlorperazine in seasickness.
    Industrial medicine & surgery, 1959, Volume: 28

    Topics: Biomedical Research; Humans; Motion Sickness; Prochlorperazine

1959
EVALUATION OF SOME ANTIMOTION SICKNESS DRUGS ON THE SLOW ROTATION ROOM (NO. 1). NSAM-922.
    Research report. Naval School of Aviation Medicine (U.S.), 1965, Volume: 15

    Topics: Biomedical Research; Dextroamphetamine; Drug Therapy; Humans; Meclizine; Motion Sickness; Pharmacolo

1965
Prevention and treatment of space sickness in shuttle-orbiter missions.
    Aviation, space, and environmental medicine, 1979, Volume: 50, Issue:2

    Topics: Adult; Delayed-Action Preparations; Dimenhydrinate; Drug Combinations; Ephedrine; Humans; Meclizine;

1979
The anti-emetic properties of 1-sulpiride in a ground-based model of space motion sickness.
    Life sciences, 1987, Oct-12, Volume: 41, Issue:15

    Topics: Animals; Antiemetics; Chlorpromazine; Disease Models, Animal; Domperidone; Female; Male; Motion Sick

1987
[On the prevention of air sickness in pilots].
    Rivista di medicina aeronautica e spaziale, 1966, Volume: 29

    Topics: Adult; Aerospace Medicine; Barbiturates; Benzamides; Histamine H1 Antagonists; Humans; Motion Sickne

1966