prochlorperazine has been researched along with Malignant Melanoma in 3 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cutaneous melanoma is least common (only about 1% of skin cancers) but is the deadliest malignant tumor." | 5.51 | Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. ( Otręba, M; Pajor, M; Warncke, JD, 2019) |
| "Two drugs known to inhibit the action of calmodulin, prochlorperazine offP) and N-(6-aminohexyl)-5-chloro-1-napthalene sulfonamide (W7), were investigated for their ability to control cell proliferation in murine B16 melanoma cells in culture." | 3.67 | Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth. ( Bleehen, SS; Mac Neil, S; Senior, HJ; Tomlinson, S; Walker, SW, 1984) |
| "Cutaneous melanoma is least common (only about 1% of skin cancers) but is the deadliest malignant tumor." | 1.51 | Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines. ( Otręba, M; Pajor, M; Warncke, JD, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Otręba, M | 1 |
| Pajor, M | 1 |
| Warncke, JD | 1 |
| POTTS, AM | 1 |
| Mac Neil, S | 1 |
| Walker, SW | 1 |
| Senior, HJ | 1 |
| Bleehen, SS | 1 |
| Tomlinson, S | 1 |
3 other studies available for prochlorperazine and Malignant Melanoma
| Article | Year |
|---|---|
Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines.
Topics: Antineoplastic Agents; Antipsychotic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Re | 2019 |
TRACER STUDIES ON A TRANSPLANTABLE HAMSTER MELANOMA.
Topics: Animals; Chlorpromazine; Cricetinae; Eye Neoplasms; Fluoresceins; Idoxuridine; Iodine Isotopes; Mela | 1964 |
Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth.
Topics: Animals; Calmodulin; Cell Line; Cells, Cultured; Culture Media; DNA, Neoplasm; Dose-Response Relatio | 1984 |