prochlorperazine has been researched along with Malaria, Falciparum in 2 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyproheptadine and verapamil were not effective in reversing chloroquine resistance and probable drug toxicity was observed with these drugs in combination with chloroquine." | 1.29 | Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys. ( Kyle, DE; Milhous, WK; Rossan, RN, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watt, G | 1 |
| Na-Nakorn, A | 1 |
| Bateman, DN | 1 |
| Plubha, N | 1 |
| Mothanaprakoon, P | 1 |
| Edstein, M | 1 |
| Webster, HK | 1 |
| Kyle, DE | 1 |
| Milhous, WK | 1 |
| Rossan, RN | 1 |
1 trial available for prochlorperazine and Malaria, Falciparum
| Article | Year |
|---|---|
Amplification of quinine cardiac effects by the resistance-reversing agent prochlorperazine in falciparum malaria.
Topics: Electrocardiography; Heart; Humans; Infusions, Intravenous; Injections, Intramuscular; Malaria, Falc | 1993 |
1 other study available for prochlorperazine and Malaria, Falciparum
| Article | Year |
|---|---|
Reversal of Plasmodium falciparum resistance to chloroquine in Panamanian Aotus monkeys.
Topics: Animals; Aotus trivirgatus; Calcium Channel Blockers; Chloroquine; Chlorpromazine; Cyproheptadine; D | 1993 |