Compounds > prochlorperazine
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prochlorperazine and Injuries, Radiation

prochlorperazine has been researched along with Injuries, Radiation in 6 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to determine the mechanism of action of radiation-induced emesis by determining the incidence of radiation-induced emesis following hemibody irradiation; the effects of specific antiemetics especially ondansetron, a 5-hydroxytryptamine receptor antagonist, and to determine the relationship between radiation-induced emesis and serotonin (5-hydroxytryptamine) through its active metabolite, 5-hydroxyindoleacetic acid (5-HIAA)."5.07On the mechanism of radiation-induced emesis: the role of serotonin. ( Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW, 1994)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SOLAN, MJ1
BERGONZINI, R2
VENDRAME, L2
DEMARIA, D2
CANOSSI, C1
MORINI, M2
REGGIANI, R1
Scarantino, CW1
Ornitz, RD1
Hoffman, LG1
Anderson, RF1
Ward, HW1
Berry, GH1
Duncan, W1
Bowman, CM1

Trials

3 trials available for prochlorperazine and Injuries, Radiation

ArticleYear
On the mechanism of radiation-induced emesis: the role of serotonin.
    International journal of radiation oncology, biology, physics, 1994, Nov-15, Volume: 30, Issue:4

    Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic

1994
Metoclopramide and prochlorperazine in radiation sickness.
    British medical journal, 1973, Apr-07, Volume: 2, Issue:5857

    Topics: Amides; Anisoles; Benzoates; Ethylamines; Humans; Prochlorperazine; Radiation Injuries

1973
The prevention of radiation sickness. Report of a double blind random clinical trial using prochlorperazine and metopimazine.
    Clinical radiology, 1971, Volume: 22, Issue:4

    Topics: Clinical Trials as Topic; Humans; Nausea; Phenothiazines; Prochlorperazine; Radiation Injuries; Radi

1971

Other Studies

3 other studies available for prochlorperazine and Injuries, Radiation

ArticleYear
Prochlorperazine and irradiation sickness.
    British medical journal, 1959, Nov-21, Volume: 2, Issue:5159

    Topics: Humans; Prochlorperazine; Psychotherapy; Radiation; Radiation Injuries; Research

1959
[ON THE RADIOPROTECTIVE POWER OF PROCHLORPERAZINE IN EXPERIMENTAL PANIRRADIATION WITH COBALT 60].
    Minerva radiologica, fisioterapica e radiobiologica, 1964, Volume: 30

    Topics: Animals; Cobalt; Cobalt Isotopes; Cobalt Radioisotopes; Cysteamine; Mice; Pharmacology; Prochlorpera

1964
[WEIGHT VARIATIONS OF ALBINO MICE SUBJECTED TO PANIRRADIATION WITH COBALT 60 AND VARIOUS AMOUNTS OF PROCHLORPERAZINE].
    Minerva radiologica, fisioterapica e radiobiologica, 1964, Volume: 30

    Topics: Animals; Body Weight; Cobalt; Cobalt Isotopes; Cobalt Radioisotopes; Mice; Pharmacology; Prochlorper

1964