prochlorperazine has been researched along with Hyperemesis Gravidarum in 11 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Hyperemesis Gravidarum: Intractable VOMITING that develops in early PREGNANCY and persists. This can lead to DEHYDRATION and WEIGHT LOSS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| "A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth." | 1.25 | Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coralic, Z | 1 |
| Kim, AS | 1 |
| Vinson, DR | 1 |
| ONGHENA, G | 1 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| Beirne, M | 1 |
| Fenton, J | 1 |
| Magee, LA | 1 |
| Redman, CW | 1 |
| Ho, CK | 1 |
| Kaufman, RL | 1 |
| McAlister, WH | 1 |
| Milkovich, L | 1 |
| van den Berg, BJ | 1 |
| Rafla, N | 1 |
| Marks, PA | 1 |
| Kammeraad, LA | 1 |
| Papp, JP | 1 |
| Farkas, G | 2 |
| Morra, C | 1 |
| Lanza, A | 1 |
3 trials available for prochlorperazine and Hyperemesis Gravidarum
| Article | Year |
|---|---|
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
An N-of-1 trial for treatment of hyperemesis gravidarum.
Topics: Adult; Antiemetics; Ascorbic Acid; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hy | 1996 |
An evaluation of the teratogenicity of certain antinauseant drugs.
Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylami | 1976 |
8 other studies available for prochlorperazine and Hyperemesis Gravidarum
| Article | Year |
|---|---|
Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
Topics: Adult; Diphenhydramine; Dystonia; Emergency Medicine; Female; Humans; Hyperemesis Gravidarum; Infusi | 2015 |
[Clinical study of prochlorperazine in hyperemesis gravidarum].
Topics: Biomedical Research; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Prochlorperazine | 1960 |
Acute dystonic reaction secondary to prochlorperazine use in the treatment of hyperemesis gravidarum.
Topics: Acute Disease; Adult; Antiemetics; Dystonia; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Proc | 2007 |
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip | 1975 |
Limb deformities associated with prochlorperazine.
Topics: Abnormalities, Drug-Induced; Female; Humans; Hyperemesis Gravidarum; Limb Deformities, Congenital; P | 1987 |
Intrahepatic cholestasis in hyperemesis gravidarum: a case report.
Topics: Cholestasis; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlorperazine | 1974 |
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec | 1971 |
[Recent etiopathogenetic concepts and new therapeutic trends in emesis gravidarum].
Topics: Acidosis; Adrenal Cortex Hormones; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlo | 1969 |