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prochlorperazine and Cholestasis

prochlorperazine has been researched along with Cholestasis in 4 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"A patient with prochlorperazine-induced cholestasis that persisted for more than 2 years is reported."7.67Prochlorperazine-induced chronic cholestasis. ( Lok, AS; Ng, IO, 1988)
"A patient with prochlorperazine-induced cholestasis that persisted for more than 2 years is reported."3.67Prochlorperazine-induced chronic cholestasis. ( Lok, AS; Ng, IO, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WEINSTEIN, A1
ALPER, BJ1
DADE, JR1
O'Brien, CB1
Shields, DS1
Saul, SH1
Reddy, KR1
Lok, AS1
Ng, IO1
Marks, PA1
Kammeraad, LA1
Papp, JP1

Reviews

1 review available for prochlorperazine and Cholestasis

ArticleYear
Drug-induced vanishing bile duct syndrome: response to ursodiol.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:7

    Topics: Antipsychotic Agents; Bile Duct Diseases; Cholagogues and Choleretics; Cholestasis; Chronic Disease;

1996

Other Studies

3 other studies available for prochlorperazine and Cholestasis

ArticleYear
Cholestasis due to prochlorperazine.
    Journal of the American Medical Association, 1959, Aug-01, Volume: 170, Issue:14

    Topics: Bile; Cholestasis; Humans; Phenothiazines; Prochlorperazine

1959
Prochlorperazine-induced chronic cholestasis.
    Journal of hepatology, 1988, Volume: 6, Issue:3

    Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Biopsy; Cholestasis; Cholesterol; Human

1988
Intrahepatic cholestasis in hyperemesis gravidarum: a case report.
    Michigan medicine, 1974, Volume: 73, Issue:20

    Topics: Cholestasis; Female; Humans; Hyperemesis Gravidarum; Liver; Pregnancy; Prochlorperazine

1974