Page last updated: 2024-11-03

prochlorperazine and Breast Neoplasms

prochlorperazine has been researched along with Breast Neoplasms in 12 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this article is to assess the comparative antiemetic efficacy of prochlorperazine, ondansetron, and dexamethasone in the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) after moderately high to highly emetogenic chemotherapy."9.11Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone. ( Amamoo, MA; Bernard, S; Goodin, S; Kane, M; Laliberte, K; Lindley, C; McCune, J; Pham, T; Schell, M; Shord, S; Socinski, MA; Yowell, S, 2005)
"The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer."9.06A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988)
"The purpose of this article is to assess the comparative antiemetic efficacy of prochlorperazine, ondansetron, and dexamethasone in the prevention of delayed chemotherapy-induced nausea and vomiting (CINV) after moderately high to highly emetogenic chemotherapy."5.11Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone. ( Amamoo, MA; Bernard, S; Goodin, S; Kane, M; Laliberte, K; Lindley, C; McCune, J; Pham, T; Schell, M; Shord, S; Socinski, MA; Yowell, S, 2005)
"The antiemetic effectiveness of haloperidol plus dexamethasone was compared with that of prochlorperazine plus dexamethasone in a prospective study of patients receiving chemotherapy for breast cancer."5.06A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer. ( Carpenter, JT; Conolley, C; Lee, J; Silvey, L; Wheeler, RH, 1988)
"sensitive breast tumors were identified from three different publically available microarray datasets."1.37An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors. ( Dai, Y; Frasor, JM; Huang, L; Zhao, S, 2011)
"Nausea was assessed on a 1-7 scale four times a day for 4 days by diary."1.36Insight in the prediction of chemotherapy-induced nausea. ( Colagiuri, B; Colman, L; Heckler, CE; Hoelzer, K; Jacobs, A; Morrow, GR; Pudlo, BD; Roscoe, JA, 2010)
" The temporal and dose-response relationships suggested a possible association between the depressive symptoms and corticosteroid."1.36Suicide associated with corticosteroid use during chemotherapy: case report. ( Kinoshita, H; Matsumoto, Y; Shimizu, C; Shimizu, K; Uchitomi, Y, 2010)
"PONV is a significant problem in breast surgical patients."1.33Prevention of nausea and vomiting following breast surgery. ( Colvert, M; Henry-Tillman, RS; Kass, R; Klimberg, VS; Layeeque, R; Mancino, A; Siegel, E, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's2 (16.67)18.2507
2000's4 (33.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roscoe, JA1
Morrow, GR1
Colagiuri, B1
Heckler, CE1
Pudlo, BD1
Colman, L1
Hoelzer, K1
Jacobs, A1
Matsumoto, Y1
Shimizu, K1
Kinoshita, H1
Shimizu, C1
Uchitomi, Y1
Huang, L1
Zhao, S1
Frasor, JM1
Dai, Y1
Sprung, J1
Choudhry, FM1
Hall, BA1
Lindley, C1
Goodin, S1
McCune, J1
Kane, M1
Amamoo, MA1
Shord, S1
Pham, T1
Yowell, S1
Laliberte, K1
Schell, M1
Bernard, S1
Socinski, MA1
Layeeque, R1
Siegel, E1
Kass, R1
Henry-Tillman, RS1
Colvert, M1
Mancino, A1
Klimberg, VS1
Trinkle, R1
Garrido, SM1
Chauncey, TR1
Silvey, L1
Carpenter, JT1
Wheeler, RH1
Lee, J1
Conolley, C1
Thorner, MO1
Volans, G1
Besser, GM1
McNeilly, AS1
Ward, HW1

Trials

2 trials available for prochlorperazine and Breast Neoplasms

ArticleYear
Prevention of delayed chemotherapy-induced nausea and vomiting after moderately high to highly emetogenic chemotherapy: comparison of ondansetron, prochlorperazine, and dexamethasone.
    American journal of clinical oncology, 2005, Volume: 28, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast

2005
A randomized comparison of haloperidol plus dexamethasone versus prochlorperazine plus dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1988, Volume: 6, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclopho

1988

Other Studies

10 other studies available for prochlorperazine and Breast Neoplasms

ArticleYear
Insight in the prediction of chemotherapy-induced nausea.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:7

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast

2010
Suicide associated with corticosteroid use during chemotherapy: case report.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Antineo

2010
An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Biological Phenomena; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Computational Biology;

2011
Extrapyramidal reactions to ondansetron: cross-reactivity between ondansetron and prochlorperazine?
    Anesthesia and analgesia, 2003, Volume: 96, Issue:5

    Topics: Adult; Antiemetics; Basal Ganglia Diseases; Breast Neoplasms; Cross Reactions; Female; Humans; Maste

2003
Prevention of nausea and vomiting following breast surgery.
    American journal of surgery, 2006, Volume: 191, Issue:6

    Topics: Administration, Oral; Administration, Rectal; Adult; Antiemetics; Breast Neoplasms; Cohort Studies;

2006
Compatibility of hydromorphone and prochlorperazine, and irritation due to subcutaneous prochlorperazine infusion.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:6

    Topics: Analgesics, Opioid; Antiemetics; Breast Neoplasms; Drug Incompatibility; Female; Humans; Hydromorpho

1997
Neuroleptic malignant syndrome following autologous peripheral blood stem cell transplantation.
    Bone marrow transplantation, 1998, Volume: 21, Issue:4

    Topics: Antipsychotic Agents; Breast Neoplasms; Droperidol; Female; Haloperidol; Hematopoietic Stem Cell Tra

1998
Case problem: presenting conventional and complementary approaches for relieving nausea in a breast cancer patient undergoing chemotherapy.
    Journal of the American Dietetic Association, 2000, Volume: 100, Issue:2

    Topics: Acupressure; Acupuncture Therapy; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols

2000
Letter: Antiemetics, prolactin, and breast cancer.
    British medical journal, 1974, Aug-17, Volume: 3, Issue:5928

    Topics: Breast Neoplasms; Cyclizine; Humans; Nausea; Prochlorperazine; Prolactin

1974
Letter: Metaclopramide and prolactin.
    British medical journal, 1974, Jul-20, Volume: 3, Issue:5924

    Topics: Breast Neoplasms; Humans; Metoclopramide; Prochlorperazine; Prolactin

1974