Page last updated: 2024-11-03

prochlorperazine and Bilateral Headache

prochlorperazine has been researched along with Bilateral Headache in 27 studies

Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.

Research Excerpts

ExcerptRelevanceReference
"We conducted a single site, randomized, double-blind, placebo-controlled trial investigating the clinical efficacy of IV acetaminophen as an adjunct to a standard therapy with prochlorperazine and diphenhydramine for the treatment of patients who present to the ED with a chief complaint of "headache" or variants thereof."9.24Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department. ( Hysell, MK; Meyering, SH; Stringer, RW, 2017)
"Previous uncontrolled, nonrandomized trials suggest that magnesium sulfate (MgSO(4)) is effective in the treatment of headache."9.09A prospective study of i.v. magnesium and i.v. prochlorperazine in the treatment of headaches. ( Ginder, S; Oatman, B; Pollack, M, 2000)
"Droperidol was more effective than prochlorperazine in relieving pain associated with benign headaches."9.09Droperidol vs. prochlorperazine for benign headaches in the emergency department. ( Biros, MH; Fish, SJ; Miner, JR; Smith, SW, 2001)
"In a prospective, randomized, double-blind clinical trial, intravenous prochlorperazine edisylate (Compazine Edisylate) was compared with a placebo in the treatment of severe headaches."9.06Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache. ( Dougherty, J; Jones, J; Sklar, D; White, W, 1989)
" Inclusion criteria was age ≥ 18 who presented to the emergency department with a chief complaint of headache who received either olanzapine, metoclopramide or prochlorperazine."8.31Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023)
"Intravenous subdissociative-dose ketamine has been shown to be effective for pain management, but has not been specifically studied for headaches in the emergency department (ED)."7.88A Comparison of Headache Treatment in the Emergency Department: Prochlorperazine Versus Ketamine. ( Bartlett, A; Clark, JM; Forred, W; Gates, M; Patel, J; Pitotti, C; Rahbar, A; Sontgerath, JS; Zitek, T, 2018)
"To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache."7.70Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache. ( Fuh, JL; Juang, KD; Lu, SR; Wang, SJ, 2000)
"Prochlorperazine was superior to promethazine in the rate of headache reduction and rate of home drowsiness, with similar rates of akathesia, nausea resolution, patient satisfaction, and headache recurrence within 5 days of discharge."6.73Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial. ( Bachrach, EA; Callan, JE; Kostic, MA; Rieg, TS, 2008)
" Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need."5.41The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023)
"Headaches were aborted using four different intravenous regimens containing 0."5.28Abortive headache therapy in the office with intravenous dihydroergotamine plus prochlorperazine. ( Saadah, HA, 1992)
"We conducted a single site, randomized, double-blind, placebo-controlled trial investigating the clinical efficacy of IV acetaminophen as an adjunct to a standard therapy with prochlorperazine and diphenhydramine for the treatment of patients who present to the ED with a chief complaint of "headache" or variants thereof."5.24Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department. ( Hysell, MK; Meyering, SH; Stringer, RW, 2017)
"Previous uncontrolled, nonrandomized trials suggest that magnesium sulfate (MgSO(4)) is effective in the treatment of headache."5.09A prospective study of i.v. magnesium and i.v. prochlorperazine in the treatment of headaches. ( Ginder, S; Oatman, B; Pollack, M, 2000)
"The utility of intravenous prochlorperazine as an antiemetic agent and abortive therapy for headache may be limited by the frequent occurrence of akathisia, the distressing effects of which have been shown to disrupt patient care."5.09Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial. ( Drotts, DL; Vinson, DR, 2001)
"Droperidol was more effective than prochlorperazine in relieving pain associated with benign headaches."5.09Droperidol vs. prochlorperazine for benign headaches in the emergency department. ( Biros, MH; Fish, SJ; Miner, JR; Smith, SW, 2001)
" Patients aged 18 years or older treated with prochlorperazine for headache, nausea, or vomiting were eligible for inclusion."5.09Intravenous administration of prochlorperazine by 15-minute infusion versus 2-minute bolus does not affect the incidence of akathisia: a prospective, randomized, controlled trial. ( Brizendine, EJ; Chisholm, CD; Collins, RW; Cordell, WH; Giles, BK; Jones, JB; Walthall, JD, 2001)
"In a prospective, randomized, double-blind clinical trial, intravenous prochlorperazine edisylate (Compazine Edisylate) was compared with a placebo in the treatment of severe headaches."5.06Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache. ( Dougherty, J; Jones, J; Sklar, D; White, W, 1989)
" For hemicrania we used cinnarizine, cyproheptadine, clonidine, histamine, pizotifene and reserpine; for cluster headache, cinnarizine, cyproheptadine, clonidine, histamine and reserpine; for tension headache, cyproheptadine; for psychogenic headache, allylpropylmalonylurea."5.04[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)]. ( Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G, 1975)
" Inclusion criteria was age ≥ 18 who presented to the emergency department with a chief complaint of headache who received either olanzapine, metoclopramide or prochlorperazine."4.31Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients. ( Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL, 2023)
"Intravenous subdissociative-dose ketamine has been shown to be effective for pain management, but has not been specifically studied for headaches in the emergency department (ED)."3.88A Comparison of Headache Treatment in the Emergency Department: Prochlorperazine Versus Ketamine. ( Bartlett, A; Clark, JM; Forred, W; Gates, M; Patel, J; Pitotti, C; Rahbar, A; Sontgerath, JS; Zitek, T, 2018)
" These studies had used a conventional Long instrument in the prospective assessment of 360 adult ED patients aged 17-65 years who received intravenous prochlorperazine (10 mg) in the treatment of headache or nausea and vomiting."3.73Development of a simplified instrument for the diagnosis and grading of akathisia in a cohort of patients receiving prochlorperazine. ( Vinson, DR, 2006)
"To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache."3.70Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache. ( Fuh, JL; Juang, KD; Lu, SR; Wang, SJ, 2000)
"Prochlorperazine was superior to promethazine in the rate of headache reduction and rate of home drowsiness, with similar rates of akathesia, nausea resolution, patient satisfaction, and headache recurrence within 5 days of discharge."2.73Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial. ( Bachrach, EA; Callan, JE; Kostic, MA; Rieg, TS, 2008)
"Headache was frequent in the control (69%), i."2.68The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison. ( van den Berg, AA, 1996)
"Prochlorperazine injection has been upgraded to a highly recommended level because of the rich clinical experience for this treatment."1.722022 Taiwan Guidelines for Acute Treatment of Migraine. ( Lau, CI; Wang, YF, 2022)
"Cerebral venous thrombosis (CVT) is a rare, difficult-to-diagnose form of venous thromboembolic disease and is considered a type of stroke."1.51Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound. ( Arthur, J; Chadwick, S; Duran-Gehring, P; Kumetz, C; McIntosh, M, 2019)
"Headaches were aborted using four different intravenous regimens containing 0."1.28Abortive headache therapy in the office with intravenous dihydroergotamine plus prochlorperazine. ( Saadah, HA, 1992)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's3 (11.11)18.2507
2000's10 (37.04)29.6817
2010's3 (11.11)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Lau, CI1
Wang, YF1
Chinn, E1
Brunette, ND1
Driver, BE1
Klein, LR1
Stang, JL1
DeVries, P1
Mojica, E1
Raiter, A1
Miner, JR2
Cole, JB1
Abdelmonem, H1
Abdelhay, HM1
Abdelwadoud, GT1
Alhosini, ANM1
Ahmed, AE1
Mohamed, SW1
Al-Dardery, NM1
Abd-ElGawad, M1
Kamel, MA1
Zitek, T2
Sigal, T1
Sun, G1
Martin Manuel, C1
Tran, K1
Meyering, SH1
Stringer, RW1
Hysell, MK1
Gates, M1
Pitotti, C1
Bartlett, A1
Patel, J1
Rahbar, A1
Forred, W1
Sontgerath, JS1
Clark, JM1
Arthur, J1
Duran-Gehring, P1
Kumetz, C1
Chadwick, S1
McIntosh, M1
Callan, JE1
Kostic, MA1
Bachrach, EA1
Rieg, TS1
Vinson, DR3
Hurtado, TR1
Vandenberg, JT1
Banwart, L1
Weaver, CS1
Jones, JB2
Chisholm, CD2
Foley, MJ1
Giles, BK2
Somerville, GG1
Brizendine, EJ2
Cordell, WH2
Twigg, J1
van den Berg, AA1
Ginder, S1
Oatman, B1
Pollack, M1
Lu, SR1
Fuh, JL1
Juang, KD1
Wang, SJ1
Drotts, DL1
Morgenstern, LB1
Huber, JC1
Luna-Gonzales, H1
Saldin, KR1
Grotta, JC1
Shaw, SG1
Knudson, L1
Frankowski, RF1
Fish, SJ1
Smith, SW1
Biros, MH1
Collins, RW1
Walthall, JD1
Nattero, G3
Agostoni, A1
Brandi, G1
Cottino, A1
Gai, V3
Gastaldi, L3
Lisino, F1
Saadah, HA1
Jones, J1
Sklar, D1
Dougherty, J1
White, W1
Clåirmont, AA1
Turner, JS1
Jackson, RT1
Barrie, MA1
Fox, WR1
Weatherall, M1
Wilkinson, MI1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130]Phase 458 participants (Actual)Interventional2017-05-16Completed
The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine. A Multi-Center, Randomized, Double-Blind, Clinical Control Trial[NCT02735343]Phase 35 participants (Actual)Interventional2016-08-31Terminated (stopped due to only recruited 5 patients at this location)
The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031]Phase 454 participants (Actual)Interventional2016-03-17Completed
A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872]Phase 4500 participants (Actual)Interventional2017-09-05Terminated (stopped due to no longer recruiting or studying)
Improving the Headache Management Care in the Emergency Unit by Using a Biological Marker: S100B Protein.[NCT03490500]63 participants (Actual)Observational2018-10-24Completed
A Randomized Double Blinded Study Comparing Use of Prochlorperazine Versus Prochlorperazine and Ketorolac in the Treatment of Pediatric Migraine in the Emergency Department[NCT01534806]Phase 40 participants (Actual)Interventional2012-01-31Withdrawn (stopped due to Drug is backordered;)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Anxiety

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm33.7
Study Arm21.2

Headache Following Intervention

Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm63.5
Study Arm43.5

Nausea

Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes

Interventionmm (Mean)
Control Arm38.9
Study Arm22.9

The Number of Participants Experiencing Vomiting

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm2
Study Arm3

The Number of Patients Experiencing Restlessness

Yes/No (NCT02657031)
Timeframe: 0-60 minutes

Interventionparticipants (Number)
Control Arm3
Study Arm3

Reviews

1 review available for prochlorperazine and Bilateral Headache

ArticleYear
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
    BMC neurology, 2023, Jun-08, Volume: 23, Issue:1

    Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea

2023

Trials

12 trials available for prochlorperazine and Bilateral Headache

ArticleYear
I-FiBH trial: intravenous fluids in benign headaches-a randomised, single-blinded clinical trial.
    Emergency medicine journal : EMJ, 2020, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Diphenhydramine; Dopamine Antagonists; Female; Fluid Therapy; Headac

2020
Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department.
    The western journal of emergency medicine, 2017, Volume: 18, Issue:3

    Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics; Diphenhydramine; Double-Blind Method;

2017
Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial.
    The Journal of emergency medicine, 2008, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Female; H

2008
Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial.
    The Journal of emergency medicine, 2008, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Female; H

2008
Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial.
    The Journal of emergency medicine, 2008, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Female; H

2008
Prochlorperazine vs. promethazine for headache treatment in the emergency department: a randomized controlled trial.
    The Journal of emergency medicine, 2008, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Female; H

2008
Droperidol vs prochlorperazine for the treatment of acute headache.
    The Journal of emergency medicine, 2004, Volume: 26, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Dopamine Antagonists;

2004
The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Antiemetics; Blood Pressure; Child; Double-Blind Method; Fem

1996
A prospective study of i.v. magnesium and i.v. prochlorperazine in the treatment of headaches.
    The Journal of emergency medicine, 2000, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Analgesics; Chi-Square Distribution; Emergency Service, Hospital; Female; Headach

2000
Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial.
    Annals of emergency medicine, 2001, Volume: 37, Issue:2

    Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antiemetics; Conscious Sedation; Diphenhydramine; Double

2001
Droperidol vs. prochlorperazine for benign headaches in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:9

    Topics: Adult; Analysis of Variance; Dopamine Antagonists; Droperidol; Emergency Service, Hospital; Female;

2001
Droperidol vs. prochlorperazine for benign headaches in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:9

    Topics: Adult; Analysis of Variance; Dopamine Antagonists; Droperidol; Emergency Service, Hospital; Female;

2001
Droperidol vs. prochlorperazine for benign headaches in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:9

    Topics: Adult; Analysis of Variance; Dopamine Antagonists; Droperidol; Emergency Service, Hospital; Female;

2001
Droperidol vs. prochlorperazine for benign headaches in the emergency department.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2001, Volume: 8, Issue:9

    Topics: Adult; Analysis of Variance; Dopamine Antagonists; Droperidol; Emergency Service, Hospital; Female;

2001
Intravenous administration of prochlorperazine by 15-minute infusion versus 2-minute bolus does not affect the incidence of akathisia: a prospective, randomized, controlled trial.
    Annals of emergency medicine, 2001, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Dose-Response Relationship, Drug; Double-Blind Met

2001
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Sep-19, Volume: 117, Issue:38

    Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, C

1975
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache.
    JAMA, 1989, Feb-24, Volume: 261, Issue:8

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Headache; Humans; Injections, Intravenous; Male;

1989
Analysis of symptoms of patients with headaches and their response to treatment with ergot derivatives.
    The Quarterly journal of medicine, 1968, Volume: 37, Issue:146

    Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Ergonovine; Ergotamine; Female; Headache

1968

Other Studies

14 other studies available for prochlorperazine and Bilateral Headache

ArticleYear
2022 Taiwan Guidelines for Acute Treatment of Migraine.
    Acta neurologica Taiwanica, 2022, Jun-30, Volume: 31(2)

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin G

2022
Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients.
    The American journal of emergency medicine, 2023, Volume: 65

    Topics: Cohort Studies; Double-Blind Method; Dystonia; Emergency Service, Hospital; Headache; Humans; Metocl

2023
A Comparison of Headache Treatment in the Emergency Department: Prochlorperazine Versus Ketamine.
    Annals of emergency medicine, 2018, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Dopamine Antagonists; Dose-Response Relationship

2018
Cerebral Venous Thrombosis: An Uncommon Cause of Papilledema on Bedside Ocular Ultrasound.
    The Journal of emergency medicine, 2019, Volume: 56, Issue:3

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Cerebral Veins; Computed Tomogra

2019
Variations among emergency departments in the treatment of benign headache.
    Annals of emergency medicine, 2003, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Aged; Algorithms; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Bino

2003
Development of a simplified instrument for the diagnosis and grading of akathisia in a cohort of patients receiving prochlorperazine.
    The Journal of emergency medicine, 2006, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Dopamine Antagonists; Female; Headach

2006
Unrecognized drug reaction.
    Nursing, 1996, Volume: 26, Issue:7

    Topics: Dysarthria; Headache; Humans; Prochlorperazine; Sialorrhea; Tachycardia

1996
Repetitive intravenous prochlorperazine treatment of patients with refractory chronic daily headache.
    Headache, 2000, Volume: 40, Issue:9

    Topics: Adult; Analgesics; Antipsychotic Agents; Female; Follow-Up Studies; Headache; Humans; Infusions, Int

2000
Headache in the emergency department.
    Headache, 2001, Volume: 41, Issue:6

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Diagnosis, Differential; Drug T

2001
Abortive headache therapy in the office with intravenous dihydroergotamine plus prochlorperazine.
    Headache, 1992, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Dihydroergotamine; Drug Therapy, Combination; Female; Headache; Humans; Inj

1992
Intravenous prochlorperazine for acute headache.
    JAMA, 1989, Jul-28, Volume: 262, Issue:4

    Topics: Acute Disease; Emergencies; Headache; Humans; Infusions, Intravenous; Migraine Disorders; Prochlorpe

1989
Dizziness: a logical approach to diagnosis and treatment.
    Postgraduate medicine, 1974, Volume: 56, Issue:2

    Topics: Adult; Anemia; Audiometry; Carotid Artery Diseases; Dimenhydrinate; Female; Headache; Humans; Hypert

1974
[Study of a test of active headache extinction].
    Rivista critica di clinica medica, 1968, Volume: 68, Issue:4

    Topics: Caffeine; Diagnosis, Differential; Headache; Humans; Indomethacin; Migraine Disorders; Prochlorperaz

1968
[Changes in hemodynamics observed during the extinction phase of headache attacks].
    Rivista critica di clinica medica, 1968, Volume: 68

    Topics: Blood Pressure; Brachial Artery; Caffeine; Headache; Hemodynamics; Humans; Indomethacin; Migraine Di

1968