prochlorperazine has been researched along with Basal Ganglia Diseases in 22 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prochlorperazine is often used to prevent opioid-induced nausea; however, this drug causes extrapyramidal symptoms." | 7.79 | [A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction]. ( Kono, B; Kurosawa, H; Takei, D; Yomiya, K, 2013) |
| "We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine." | 7.68 | Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991) |
| "Prochlorperazine is often used to prevent opioid-induced nausea; however, this drug causes extrapyramidal symptoms." | 3.79 | [A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction]. ( Kono, B; Kurosawa, H; Takei, D; Yomiya, K, 2013) |
| "We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine." | 3.68 | Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991) |
| "Pediatric migraine is a common, chronic, and disabling neurological disorder in children and adolescents." | 2.66 | Intravenous Migraine Treatment in Children and Adolescents. ( Hershey, AD; Kabbouche, M; Maconochie, I; Murphy, B; Qaiser, S; Werner, K, 2020) |
| "Prochlorperazine was used in all EPS patients." | 1.36 | [Antiemetic-induced extrapyramidal symptoms seen by our palliative care team]. ( Ito, T; Kawamoto, M; Matsunaga, A; Nakanuno, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Werner, K | 1 |
| Qaiser, S | 1 |
| Kabbouche, M | 1 |
| Murphy, B | 1 |
| Maconochie, I | 1 |
| Hershey, AD | 1 |
| Yomiya, K | 1 |
| Takei, D | 1 |
| Kurosawa, H | 1 |
| Kono, B | 1 |
| Nakanuno, R | 1 |
| Ito, T | 1 |
| Matsunaga, A | 1 |
| Kawamoto, M | 1 |
| Sprung, J | 1 |
| Choudhry, FM | 1 |
| Hall, BA | 1 |
| DELAY, J | 1 |
| DENIKER, P | 1 |
| FOURMENT, J | 1 |
| GREEN, A | 1 |
| ROPERT, M | 1 |
| FREYHAN, FA | 1 |
| LYNCH, B | 1 |
| HOOVER, DE | 1 |
| DARLING, HF | 1 |
| BORENSTEIN, P | 1 |
| DABBAH, M | 1 |
| BLES, G | 1 |
| MARZUOLI, U | 1 |
| GRASSANO, MC | 1 |
| RUBINO, R | 1 |
| SCIME, IA | 1 |
| TALLANT, EJ | 1 |
| Baker, FM | 1 |
| Cook, P | 1 |
| Carey, MJ | 1 |
| Aitken, ME | 1 |
| Muñiz, AE | 1 |
| Poster, DS | 1 |
| Rodgers, C | 1 |
| Factor, SA | 1 |
| Matthews, MK | 1 |
| Bateman, DN | 2 |
| Darling, WM | 1 |
| Boys, R | 1 |
| Rawlins, MD | 2 |
| Skorin, L | 1 |
| Onofrey, BE | 1 |
| DeWitt, JD | 1 |
| Simpson, JM | 1 |
| Marcotte, DB | 1 |
2 reviews available for prochlorperazine and Basal Ganglia Diseases
| Article | Year |
|---|---|
Intravenous Migraine Treatment in Children and Adolescents.
Topics: Administration, Intravenous; Adolescent; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Inflammat | 2020 |
Compazine complications: a review.
Topics: Adolescent; Adult; Antiemetics; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Dystonia; Female; | 1981 |
20 other studies available for prochlorperazine and Basal Ganglia Diseases
| Article | Year |
|---|---|
[A study on the antiemetic effect and extrapyramidal symptoms of prochlorperazine versus perospirone for the control of nausea and vomiting due to opioid introduction].
Topics: Antiemetics; Basal Ganglia Diseases; Female; Humans; Isoindoles; Male; Middle Aged; Nausea; Neoplasm | 2013 |
[Antiemetic-induced extrapyramidal symptoms seen by our palliative care team].
Topics: Aged; Analgesics, Opioid; Antiemetics; Basal Ganglia Diseases; Female; Humans; Male; Middle Aged; Pa | 2010 |
Extrapyramidal reactions to ondansetron: cross-reactivity between ondansetron and prochlorperazine?
Topics: Adult; Antiemetics; Basal Ganglia Diseases; Breast Neoplasms; Cross Reactions; Female; Humans; Maste | 2003 |
[New types of neurological complications caused by a new neuroleptic drug, prochlorperazine].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Disease; Extrapyramidal Tracts; Humans; Phenothiazines | 1957 |
[Psychomotility, extrapyramidal syndrome and mode of action of neuroleptic therapies; chlorpromazine, reserpine and prochlorperazine].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans | 1957 |
Extrapyramidal syndrome due to compazine therapy. Review of a case.
Topics: Basal Ganglia Diseases; Disease; Extrapyramidal Tracts; Humans; Prochlorperazine | 1961 |
Extrapyramidal symptoms of triflupromazine, mepazine, prochlorperazine.
Topics: Basal Ganglia Diseases; Extrapyramidal Tracts; Humans; Phenothiazines; Prochlorperazine; Tranquilizi | 1959 |
[Apropos of the ultimate specificity of terrain in the appearance of extrapyramidal syndromes induced by neuroleptic agents].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Extrapyramidal Tracts; Haloperidol; Humans; Parkinson | 1962 |
[EXTRAPYRAMIDAL SYNDROME WITH SUBINTRANT OCULOGYRIC CRISES DUE TO PROCHLORPEMAZINE THERAPY. APROPOS OF A CASE].
Topics: Basal Ganglia Diseases; Extrapyramidal Tracts; Eye Movements; Humans; Influenza, Human; Movement Dis | 1965 |
Tetanus-like reactions to prochlorperazine (compazine): report of eight cases exhibiting extrapyramidal disturbances after small doses.
Topics: Basal Ganglia Diseases; Disease; Extrapyramidal Tracts; Humans; Prochlorperazine; Tetanus; Tetanus T | 1959 |
Diverse effects of antiemetics in children.
Topics: Antiemetics; Basal Ganglia Diseases; Child; Child, Preschool; Drug Overdose; Female; Gastroenteritis | 1994 |
Prochlorperazine-induced extrapyramidal effects mimicking meningitis in a child.
Topics: Antiemetics; Basal Ganglia Diseases; Child, Preschool; Diagnosis, Differential; Female; Humans; Meni | 2000 |
Procarbazine-prochlorperazine interaction: an underreported phenomenon.
Topics: Adult; Basal Ganglia Diseases; Drug Interactions; Humans; Lymphoma, Non-Hodgkin; Male; Procarbazine; | 1978 |
Extrapyramidal side effects of antiemetics presenting as psychiatric illness.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Anxiety Disor | 1992 |
Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy.
Topics: Basal Ganglia Diseases; Cerebral Palsy; Dystonia; Female; Humans; Intellectual Disability; Metoclopr | 1991 |
Extrapyramidal reactions to metoclopramide and prochlorperazine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Basal Ganglia Diseases; Child; | 1989 |
Phenothiazine-induced oculogyric crisis.
Topics: Adult; Basal Ganglia Diseases; Colonic Diseases, Functional; Drug Combinations; Female; Humans; Proc | 1987 |
Extrapyramidal reactions to prochlorperazine and haloperidol in the United Kingdom.
Topics: Adolescent; Adult; Age Factors; Basal Ganglia Diseases; Dyskinesia, Drug-Induced; Dystonia; Female; | 1986 |
Neuroleptics and neurologic reactions.
Topics: Adolescent; Adult; Antipsychotic Agents; Athetosis; Basal Ganglia Diseases; Female; Humans; Mesorida | 1973 |
Drug-induced extrapyramidal symptoms. A cooperative study.
Topics: Antidepressive Agents; Antipsychotic Agents; Basal Ganglia Diseases; Butyrophenones; Chlorpromazine; | 1973 |