prochlorperazine has been researched along with Adverse Drug Event in 8 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prochlorperazine is recommended for adults with breakthrough or refractory chemotherapy-induced nausea and vomiting (CINV)." | 4.93 | The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis. ( Dupuis, LL; Flank, J; Lau Moon Lin, M; Robinson, PD; Sung, L, 2016) |
| "Prescribers should consider the possible contributing role of newly initiated medicines with the potential to cause of dizziness, and where possible address this through dose reduction or cessation of the medicine, rather than prescribing prochlorperazine." | 3.76 | Increased risk of hip fracture in the elderly associated with prochlorperazine: is a prescribing cascade contributing? ( Caughey, GE; Gilbert, AL; Pratt, N; Roughead, EE; Shakib, S; Vitry, AI, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Kirkpatrick, L | 1 |
| Sogawa, Y | 1 |
| Cleves, C | 1 |
| Lau Moon Lin, M | 1 |
| Robinson, PD | 1 |
| Flank, J | 1 |
| Sung, L | 1 |
| Dupuis, LL | 1 |
| Caughey, GE | 1 |
| Roughead, EE | 1 |
| Pratt, N | 1 |
| Shakib, S | 1 |
| Vitry, AI | 1 |
| Gilbert, AL | 1 |
| Jarvik, ME | 1 |
1 review available for prochlorperazine and Adverse Drug Event
| Article | Year |
|---|---|
The Safety of Prochlorperazine in Children: A Systematic Review and Meta-Analysis.
Topics: Antiemetics; Antineoplastic Agents; Chemotherapy-Induced Febrile Neutropenia; Child; Child Health Se | 2016 |
7 other studies available for prochlorperazine and Adverse Drug Event
| Article | Year |
|---|---|
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Acute Dystonic Reactions in Children Treated for Headache With Prochlorperazine or Metoclopramide.
Topics: Adolescent; Child; Dopamine Antagonists; Drug-Related Side Effects and Adverse Reactions; Dystonia; | 2020 |
Increased risk of hip fracture in the elderly associated with prochlorperazine: is a prescribing cascade contributing?
Topics: Aged; Aged, 80 and over; Antiemetics; Australia; Databases, Factual; Dizziness; Drug-Related Side Ef | 2010 |
Marihuana for nausea and vomiting due to cancer chemotherapy.
Topics: Dronabinol; Drug-Related Side Effects and Adverse Reactions; Humans; Nausea; Neoplasms; Prochlorpera | 1980 |
Necessary risks.
Topics: Animals; Antiemetics; Dogs; Dronabinol; Drug Industry; Drug-Related Side Effects and Adverse Reactio | 1979 |