prochlorperazine has been researched along with Abnormalities, Drug-Induced in 14 studies
Prochlorperazine: A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
prochlorperazine : A member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth." | 1.25 | Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WINBERG, J | 2 |
| BIAGI, GL | 1 |
| GATLING, RR | 1 |
| Reis, M | 1 |
| Källén, B | 1 |
| Rise, A | 1 |
| Ho, CK | 1 |
| Kaufman, RL | 1 |
| McAlister, WH | 1 |
| Milkovich, L | 1 |
| van den Berg, BJ | 1 |
| Rafla, N | 1 |
| Hill, RM | 1 |
| Verniaud, WM | 1 |
| Horning, MG | 1 |
| McCulley, LB | 1 |
| Morgan, NF | 1 |
| Vichi, F | 1 |
| Farkas, G | 2 |
| Roizin, L | 1 |
| Kaufman, MA | 1 |
| Gold, G | 1 |
| Iyengar, VK | 1 |
| Liu, JC | 1 |
| Keoseian, S | 1 |
| Freeman, R | 1 |
2 reviews available for prochlorperazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[CONGENITAL ABNORMALITIES CAUSED BY CHEMICAL AGENTS AND DEFICIENCIES. I].
Topics: Abnormalities, Drug-Induced; Alkaloids; Amino Acids; Anti-Bacterial Agents; Antibodies; Congenital A | 1964 |
[Neuroleptics in experimental teratogenesis].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chlorpromazine; Fluphenazine; Haloperidol; Mice; | 1968 |
1 trial available for prochlorperazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
An evaluation of the teratogenicity of certain antinauseant drugs.
Topics: Abnormalities, Drug-Induced; Antiemetics; Clinical Trials as Topic; Cyclizine; Dicyclomine; Doxylami | 1976 |
11 other studies available for prochlorperazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Ca | 1964 |
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
EFFECT OF NICOTINE ON CHICK EMBRYO.
Topics: Abnormalities, Drug-Induced; Chick Embryo; Cortisone; Epinephrine; Hematoma; Hemorrhage; Nicotine; N | 1964 |
Maternal use of antipsychotics in early pregnancy and delivery outcome.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Antiemetics; Antipsychotic Agents; Cesarean Sec | 2008 |
[Neuroleptics].
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenaz | 1976 |
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip | 1975 |
Limb deformities associated with prochlorperazine.
Topics: Abnormalities, Drug-Induced; Female; Humans; Hyperemesis Gravidarum; Limb Deformities, Congenital; P | 1987 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro | 1974 |
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec | 1971 |
A multidisciplinary investigation of the phenothiazines.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Cardiovascular System; Chlorpromazine; Digestive System | 1966 |
Limb deformities: possible association with drugs.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Arm; Female; Humans; Infant, Newborn; Leg; Male; Pregnan | 1972 |